-
1
-
-
84863097110
-
-
doi: 10.1371/journal.pone.0039768
-
Arnusch, C. J., Pieters, R. J., and Breukink, E. (2012). Enhanced membrane pore formation through high-affnity targeted antimicrobial peptides. PLoS ONE 7, e39768. doi: 10.1371/journal.pone.0039768
-
(2012)
Enhanced membrane pore formation through high-affnity targeted antimicrobial peptides. PLoS ONE
, vol.7
-
-
Arnusch, C.J.1
Pieters, R.J.2
Breukink, E.3
-
2
-
-
0037667047
-
Large-scale manufacture of peptide therapeutics by chemical synthesis
-
Bray, L. B. (2003). Large-scale manufacture of peptide therapeutics by chemical synthesis. Nat. Rev. Drug Discov. 2, 587-593.
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 587-593
-
-
Bray, L.B.1
-
3
-
-
80051546187
-
Wil l new generations of modifed antimicrobial peptides improve their potential as pharmaceuticals
-
Brogden, N. K., and Brogden, K. A. (2011). Wil l new generations of modifed antimicrobial peptides improve their potential as pharmaceuticals? Int. J. Antimicrob. Agents 38, 217- 225.
-
(2011)
Int J. Antimicrob. Agents
, vol.38
, pp. 217-225
-
-
Brogden, N.K.1
Brogden, K.A.2
-
4
-
-
34249709500
-
Complexities of targeting innate immunity to treat infection
-
Brown, K. L., Cosseau, C., Gardy, J. L., and Hancock, R. E. W. (2007). Complexities of targeting innate immunity to treat infection. Trends Immunol. 28, 260-266.
-
(2007)
Trends Immunol
, vol.28
, pp. 260-266
-
-
Brown, K.L.1
Cosseau, C.2
Gardy, J.L.3
Hancock, R.E.W.4
-
5
-
-
79961095617
-
Control of bacterial persister cells by trp/ arg-containing antimicrobial peptides
-
Chen, X., Zhang, M., Zhou, C., Kallenbach, N. R., and Ren, D. (2011). Control of bacterial persister cells by trp/ arg-containing antimicrobial peptides. Appl. Environ. Microbiol. 77, 4878-4885.
-
(2011)
Appl. Environ. Microbiol.
, vol.77
, pp. 4878-4885
-
-
Chen, X.1
Zhang, M.2
Zhou, C.3
Kallenbach, N.R.4
Ren, D.5
-
6
-
-
79955540343
-
In vitro activities against cystic fbrosis pathogens of synthetic host defence pro-peptides processed by neutrophil elastase
-
Desgranges, S., Le Prieult, F., Daly, A., Lydon, J., Brennan, M., Rai, D. K., et al. (2011). In vitro activities against cystic fbrosis pathogens of synthetic host defence pro-peptides processed by neutrophil elastase. Antimicrob. Agents Chemother. 55, 2487-2489.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 2487-2489
-
-
Desgranges, S.1
Le Prieult, F.2
Daly, A.3
Lydon, J.4
Brennan, M.5
Rai, D.K.6
-
7
-
-
84859133287
-
β-Lactam-host defence peptide conjugates as antibiotic prodrug candidates targeting resistant bacteria
-
Desgranges, S., Ruddle, C. C., Burke, L. P., McFadden, T. M., O'Brien, J. E., Fitzgerald-Hughes, D., et al. (2012). β-Lactam-host defence peptide conjugates as antibiotic prodrug candidates targeting resistant bacteria. RSC Adv. 2, 2480-2492.
-
(2012)
RSC Adv
, vol.2
, pp. 2480-2492
-
-
Desgranges, S.1
Ruddle, C.C.2
Burke, L.P.3
McFadden, T.M.4
O'Brien, J.E.5
Fitzgerald-Hughes, D.6
-
8
-
-
33750584025
-
Targeted killing of Streptococcus mutans by a pheromone-guided "Smart" antimicrobial peptide
-
Eckert, R., He, J., Yarbrough, D. K., Qi, F., Anderson, M. H., and Shi, W. (2006). Targeted killing of Streptococcus mutans by a pheromone-guided "Smart" antimicrobial peptide. Antimicrob. Agents Chemother. 50, 3651-3657.
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 3651-3657
-
-
Eckert, R.1
He, J.2
Yarbrough, D.K.3
Qi, F.4
Anderson, M.H.5
Shi, W.6
-
9
-
-
2942670459
-
Can innate immunity be enhanced to treat microbial infections
-
Finlay, B. B., and Hancock, R. E. W. (2004). Can innate immunity be enhanced to treat microbial infections? Nat. Rev. Microbiol. 2, 497-504.
-
(2004)
Nat Rev. Microbiol.
, vol.2
, pp. 497-504
-
-
Finlay, B.B.1
Hancock, R.E.W.2
-
10
-
-
84857411069
-
Designing antimicrobial peptides: form follows function
-
Fjell, C. D., Hiss, J. A., Hancock, R. E. W., and Schneider, G. (2012). Designing antimicrobial peptides: form follows function. Nat. Rev. Drug Discov. 11, 37-51.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 37-51
-
-
Fjell, C.D.1
Hiss, J.A.2
Hancock, R.E.W.3
Schneider, G.4
-
11
-
-
59349093299
-
Targeted antimicrobial activity of a specifc IgG-SMAP28 conjugate against Porphyromonas gin-givalis in a mixed culture
-
Franzman, M. R., Burnell, K. K., Dehkordi-Vakil, F. H., Guthmiller, J. M., Dawson, D. V., and Brogden, K. A. (2009). Targeted antimicrobial activity of a specifc IgG-SMAP28 conjugate against Porphyromonas gin-givalis in a mixed culture. Int. J. Antimicrob. Agents 33, 14-20.
-
(2009)
Int. J. Antimicrob. Agents
, vol.33
, pp. 14-20
-
-
Franzman, M.R.1
Burnell, K.K.2
Dehkordi-Vakil, F.H.3
Guthmiller, J.M.4
Dawson, D.V.5
Brogden, K.A.6
-
12
-
-
0034036205
-
In vitro activities of membrane-active peptides alone and in combination with clinically used antimicrobial agents against Stenotrophomonas maltophilia
-
Giacometti, A., Cirioni, O., Del Prete, M. S., Barchiesi, F., Fortuna, M., Drenaggi, D., et al. (2000). In vitro activities of membrane-active peptides alone and in combination with clinically used antimicrobial agents against Stenotrophomonas maltophilia. Antimicrob. Agents Chemother. 44, 1716-1719.
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 1716-1719
-
-
Giacometti, A.1
Cirioni, O.2
Del Prete, M.S.3
Barchiesi, F.4
Fortuna, M.5
Drenaggi, D.6
-
13
-
-
84858381864
-
Modulating immunity as a therapy for bacterial infections
-
Hancock, R. E., Nijnik, A., and Philpott, D. J. (2012). Modulating immunity as a therapy for bacterial infections. Nat. Rev. Microbiol. 10, 243-254.
-
(2012)
Nat. Rev. Microbiol.
, vol.10
, pp. 243-254
-
-
Hancock, R.E.1
Nijnik, A.2
Philpott, D.J.3
-
14
-
-
0035496012
-
Cationic peptides: effectors in innate immunity and novel antimicrobials
-
Hancock, R. E. W. (2001). Cationic peptides: effectors in innate immunity and novel antimicrobials. Lancet Infect. Dis. 1, 156-164.
-
(2001)
Lancet Infect. Dis.
, vol.1
, pp. 156-164
-
-
Hancock, R.E.W.1
-
15
-
-
33845699790
-
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
-
Hancock, R. E. W., and Sahl, H.-G. (2006). Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat. Biotechnol. 24, 1551-1557.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1551-1557
-
-
Hancock, R.E.W.1
Sahl, H.-G.2
-
16
-
-
0037362655
-
Effect of pegyla-tion on pharmaceuticals
-
Harris, J. M., and Chess, R. B. (2003). Effect of pegyla-tion on pharmaceuticals. Nat. Rev. Drug Discov. 2, 214-221.
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 214-221
-
-
Harris, J.M.1
Chess, R.B.2
-
17
-
-
34948886156
-
Action mechanism of PEGylated magainin 2 analogue pep-tide
-
Imura, Y., Nishida, M., and Matsuzaki, K. (2007). Action mechanism of PEGylated magainin 2 analogue pep-tide. Biochim. Biophys. Acta 1768, 2578-2585.
-
(2007)
Biochim. Biophys. Acta
, vol.1768
, pp. 2578-2585
-
-
Imura, Y.1
Nishida, M.2
Matsuzaki, K.3
-
18
-
-
82255179791
-
Synthesis of mutual azo prodrugs of anti-infammatory agents and peptides facilitated by α-aminoisobutyric acid
-
Kennedy, D. A., Vembu, N., Fronczek, F. R., and Devocelle, M. (2011). Synthesis of mutual azo prodrugs of anti-infammatory agents and peptides facilitated by α-aminoisobutyric acid. J. Org. Chem. 76, 9641-9647.
-
(2011)
J. Org. Chem.
, vol.76
, pp. 9641-9647
-
-
Kennedy, D.A.1
Vembu, N.2
Fronczek, F.R.3
Devocelle, M.4
-
19
-
-
16844381949
-
"Overview: antimicrobial peptides, as seen from a rearview mirror," in Mammalian Host Defense Peptides, eds D
-
Lehrer, R. I. (2004). "Overview: antimicrobial peptides, as seen from a rearview mirror," in Mammalian Host Defense Peptides, eds D. A. Devine and R. E. W. Hancock (Cambridge: Cambridge University Press), 5-8.
-
(2004)
A. Devine and R. E. W. Hancock (Cambridge: Cambridge University Press)
, pp. 5-8
-
-
Lehrer, R.I.1
-
20
-
-
71449112958
-
Design and characterization of an acid-activated antimicrobial peptide
-
Li, L., He, J., Eckert, R., Yarbrough, D., Lux, R., Anderson, M., et al. (2010). Design and characterization of an acid-activated antimicrobial peptide. Chem. Biol. Drug Des. 75, 127-132.
-
(2010)
Chem. Biol. Drug Des.
, vol.75
, pp. 127-132
-
-
Li, L.1
He, J.2
Eckert, R.3
Yarbrough, D.4
Lux, R.5
Anderson, M.6
-
21
-
-
80054062747
-
Recombinant production of antimicrobial peptides in Escherichia coli: a review
-
Li, Y. (2011). Recombinant production of antimicrobial peptides in Escherichia coli: a review. Protein Expr. Purif. 80, 260-267.
-
(2011)
Protein Expr. Purif.
, vol.80
, pp. 260-267
-
-
Li, Y.1
-
22
-
-
33746842648
-
Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment
-
Mader, J. S., and Hoskin, D. W. (2006). Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment. Expert Opin. Investig. Drugs 15, 933-946.
-
(2006)
Expert Opin. Investig. Drugs
, vol.15
, pp. 933-946
-
-
Mader, J.S.1
Hoskin, D.W.2
-
23
-
-
80255137006
-
Bioactivity of WLBU2 peptide antibiotic in combination with bioerodible polymer
-
McClanahan, J. R., Peyyala, R., Mahajan, R., Montelaro, R. C., Novak, K. F., and Puleo, D. A. (2011). Bioactivity of WLBU2 peptide antibiotic in combination with bioerodible polymer. Int. J. Antimicrob. Agents 38, 530-533.
-
(2011)
Int. J. Antimicrob. Agents
, vol.38
, pp. 530-533
-
-
McClanahan, J.R.1
Peyyala, R.2
Mahajan, R.3
Montelaro, R.C.4
Novak, K.F.5
Puleo, D.A.6
-
24
-
-
27144504220
-
Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus
-
Mygind, P. H., Fischer, R. L., Schnorr, K. M., Hansen, M. T., Sönksen, C. P., Ludvigsen, S., et al. (2005). Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus. Nature 437, 975-980.
-
(2005)
Nature
, vol.437
, pp. 975-980
-
-
Mygind, P.H.1
Fischer, R.L.2
Schnorr, K.M.3
Hansen, M.T.4
Sönksen, C.P.5
Ludvigsen, S.6
-
25
-
-
18544366816
-
Host defense peptides as new weapons in cancer treatment
-
Papo, N., and Shai, Y. (2005). Host defense peptides as new weapons in cancer treatment. Cell. Mol. Life Sci. 62, 784-790.
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 784-790
-
-
Papo, N.1
Shai, Y.2
-
26
-
-
0342437513
-
Improvement of oral peptide bioavailability: peptidomimetics and prodrug strategies
-
Pauletti, G. M., Gangwar, S., Siahaan, T. J., Aubé, J., and Borchardt, R. T. (1997). Improvement of oral peptide bioavailability: peptidomimetics and prodrug strategies. Ad v. D r u g D e liv. Re v. 27, 235-256.
-
(1997)
Ad v. D r u g D e liv. Re
, vol.27
, pp. 235-256
-
-
Pauletti, G.M.1
Gangwar, S.2
Siahaan, T.J.3
Aubé, J.4
Borchardt, R.T.5
-
27
-
-
33745217570
-
The co-evolution of host cationic antimicrobial peptides and microbial resistance
-
Peschel, A., and Sahl, H.-G. (2006). The co-evolution of host cationic antimicrobial peptides and microbial resistance. Nat. Rev. Microbiol. 4, 529-536.
-
(2006)
Nat. Rev. Microbiol.
, vol.4
, pp. 529-536
-
-
Peschel, A.1
Sahl, H.-G.2
-
28
-
-
2542630471
-
Fusion proteins comprising a Fusarium-specifc antibody linked to antifungal peptides protect plants against a fungal pathogen
-
Peschen, D., Li, H.-P., Fischer, R., Kreuzaler, F., and Liao, Y.-C. (2004). Fusion proteins comprising a Fusarium-specifc antibody linked to antifungal peptides protect plants against a fungal pathogen. Nat. Biotechnol. 22, 732-738.
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 732-738
-
-
Peschen, D.1
Li, H.-P.2
Fischer, R.3
Kreuzaler, F.4
Liao, Y.-C.5
-
29
-
-
77955967899
-
Dual-acting hybrid antibiotics: a promising strategy to combat bacterial resistance
-
Pokrovskaya, V., and Baasov, T. (2010). Dual-acting hybrid antibiotics: a promising strategy to combat bacterial resistance. Expert Opin. Drug Discov. 5, 883-902.
-
(2010)
Expert Opin. Drug Discov.
, vol.5
, pp. 883-902
-
-
Pokrovskaya, V.1
Baasov, T.2
-
30
-
-
10744228928
-
An engineered multidomain bactericidal peptide as a model for targeted antibiotics against specific bacteria
-
Qiu, X.-Q., Wang, H., Lu, X.-F., Zhang, J., Li, S.-F., Cheng, G., et al. (2003). An engineered multidomain bactericidal peptide as a model for targeted antibiotics against specific bacteria. Nat. Biotechnol. 21, 1480-1485.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1480-1485
-
-
Qiu, X.-Q.1
Wang, H.2
Lu, X.-F.3
Zhang, J.4
Li, S.-F.5
Cheng, G.6
-
31
-
-
40149088986
-
Prodrugs: design and clinical applications
-
Rautio, J., Kumpulainen, H., Heimbach, T., Oliyai, R., Oh, D., Järvinen, T., et al. (2008). Prodrugs: design and clinical applications. Nat. Rev. Drug Discov. 7, 255-270.
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 255-270
-
-
Rautio, J.1
Kumpulainen, H.2
Heimbach, T.3
Oliyai, R.4
Oh, D.5
Järvinen, T.6
-
33
-
-
33746141286
-
Design of a peptibody consisting of the antimicrobial peptide dhvar5 and a llama variable heavy-chain antibody fragment
-
Szynol, A., de Haard, J. J. W., Veerman, E. C., de Soet, J. J., and van Nieuw Amerongen, A. V. (2006). Design of a peptibody consisting of the antimicrobial peptide dhvar5 and a llama variable heavy-chain antibody fragment. Chem. Biol. Drug Des. 67, 425-431.
-
(2006)
Chem. Biol. Drug Des.
, vol.67
, pp. 425-431
-
-
Szynol, A.1
de Haard, J.J.W.2
Veerman, E.C.3
de Soet, J.J.4
van Nieuw Amerongen, A.V.5
-
34
-
-
84864538606
-
Nanotools for the delivery of antimicrobial peptides
-
Urbán, P., Valle-Delgado, J. J., Moles, E., Marques, J., Díez, C., and Fernàndez-Busquets, X. (2012). Nanotools for the delivery of antimicrobial peptides. Curr. Drug Targets 13, 1158-1172.
-
(2012)
Curr. Drug Targets
, vol.13
, pp. 1158-1172
-
-
Urbán, P.1
Valle-Delgado, J.J.2
Moles, E.3
Marques, J.4
Díez, C.5
Fernàndez-Busquets, X.6
-
35
-
-
34548045312
-
Unifying themes in host defence effector polypeptides
-
Yeaman, M. R., and Yount, N. Y. (2007). Unifying themes in host defence effector polypeptides. Nat. Rev. Microbiol. 5, 727-740.
-
(2007)
Nat. Rev. Microbiol.
, vol.5
, pp. 727-740
-
-
Yeaman, M.R.1
Yount, N.Y.2
-
36
-
-
84855865471
-
Emerging themesand therapeutic prospects for anti-infective peptides
-
Yount, N. Y., and Yeaman, M. R. (2012). Emerging themesand therapeutic prospects for anti-infective peptides. Annu. Rev. Pharmacol. Toxicol. 52, 337-360.
-
(2012)
Annu. Rev. Pharmacol. Toxicol.
, vol.52
, pp. 337-360
-
-
Yount, N.Y.1
Yeaman, M.R.2
-
37
-
-
0037165196
-
Antimicrobial peptides of multicel-lular organisms
-
Zasloff, M. (2002). Antimicrobial peptides of multicel-lular organisms. Nature 415, 389-395.
-
(2002)
Nature
, vol.415
, pp. 389-395
-
-
Zasloff, M.1
|