Synthesis and anti-cancer activity evaluation of new dimethoxylated chalcone and flavanone analogs

Archiv der Pharmazie

Volumn 347, Issue 11, 2014, Pages 853-860

  Ketabforoosh, Shima H M E ^a   Kheirollahi, Asma ^b   Safavi, Maliheh ^c   Esmati, Nasim ^d   Ardestani, Sussan K ^b   Emami, Saeed ^e   Firoozpour, Loghman ^d   Shafiee, Abbas ^f   Foroumadi, Alireza ^d,f  

^a LORESTAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF TEHRAN   (Iran)

^c IRANIAN RESEARCH ORGANIZATION FOR SCIENCE AND TECHNOLOGY IROST   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^f TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Anti cancer agents; Apoptosis; Chalcone; Cytotoxicity; Flavanone

Indexed keywords

1 (2 HYDROXY 4 [2 (PYRROLIDIN 1 YL)ETHOXY]PHENYL) 3 (3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 (2 HYDROXYPHENYL) 3 (3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 2 (3 CHLORO 4,5 DIMETHOXYPHENYL) 2,3 DIHYDROCHROMEN 4 ONE; 2 (3,4 DIMETHOXYPHENYL) 2,3 DIHYDROCHROMEN 4 ONE; 2 (3,4 DIMETHOXYPHENYL) 7 [2 (PYRROLIDIN 1 YL)ETHOXY] 2,3 DIHYDROCHROMEN 4 ONE; 2 (3,4,5 TRIMETHOXYPHENYL) 2,3 DIHYDROCHROMEN 4 ONE; 3 (3 BROMO 4,5 DIMETHOXYPHENYL) 1 (2 HYDROXYPHENYL) PROP 2 EN 1 ONE; 3 (3 CHLORO 4,5 DIMETHOXYPHENYL) 1 (2 HYDROXYPHENYL) PROP 2 EN 1 ONE; 3 (3,4 DIMETHOXYPHENYL) 1 (2-HYDROXYPHENYL)PROP 2 EN 1 ONE; 3 (3,4 DIMETHOXYPHENYL) 1 [2 HYDROXY 4 [2 (PYRROLIDIN 1 YL)ETHOXY]PHENYL]PROP 2 EN 1 ONE; 7 [2 (PYRROLIDIN 1 YL)ETHOXY] 2 (3,4,5 TRIMETHOXYPHENYL) 2,3 DIHYDROCHROMEN 4 ONE; ANTINEOPLASTIC AGENT; CHALCONE DERIVATIVE; DIMETHOXYLATED CHALCONE; FLAVANONE DERIVATIVE; UNCLASSIFIED DRUG; FLAVANONE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL LINE; CANCER INHIBITION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC50; INFRARED SPECTROSCOPY; MTT ASSAY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; APOPTOSIS; CELL SURVIVAL; CHEMICAL STRUCTURE; DOSE RESPONSE; DRUG DESIGN; DRUG EFFECTS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; MCF 7 CELL LINE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL SURVIVAL; CHALCONES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; FLAVANONES; FLOW CYTOMETRY; HUMANS; INHIBITORY CONCENTRATION 50; MCF-7 CELLS; MICROSCOPY, FLUORESCENCE; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84921686478     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201400215     Document Type: Article

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