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Volumn 92, Issue , 2015, Pages 672-681

Indenopyrazole oxime ethers: Synthesis and β1-adrenergic blocking activity

(13) Angelone, Tommaso a Caruso, Anna a Rochais, Christophe b Caputo, Angela Maria a Cerra, Maria Carmela a Dallemagne, Patrick b Filice, Elisabetta a Genest, David b Pasqua, Teresa a Puoci, Francesco a Saturnino, Carmela c Sinicropi, Maria Stefania a El Kashef, Hussein d

a UNIVERSITY OF CALABRIA (Italy)

b CENTRE D ETUDES ET DE RECHERCHE SUR LE MÉDICAMENT DE NORMANDIE (France)

c UNIVERSITY OF SALERNO (Italy)

d Assiut University (Egypt)

Author keywords

Hydroxypropanolamines; Indenopyrazole oximes; Indenopyrazoles; Adrenergic blocking agents; adrenoceptors

Indexed keywords

1 METHYL 1H INDENO[1,2 C]PYRAZOL 4 ONE; 1 METHYL 1H INDENO[1,2 C]PYRAZOL 4 ONE O (OXIRANYLMETHYL)OXIME; 1 METHYL 1H INDENO[1,2 C]PYRAZOL 4 ONE O [(2 HYDROXY 3 (ISOPROPYLAMINO)PROPYL]OXIME; 1 METHYL 1H INDENO[1,2 C]PYRAZOL 4 ONE O [(3 N BUTYLAMINO) 2 HYDROXYPROPYL]OXIME; 1 METHYL 1H INDENO[1,2 C]PYRAZOL 4 ONE OXIME; 1 PHENYL 1H INDENO[1,2 C]PYRAZOL 4 ONE; 1 PHENYL 1H INDENO[1,2 C]PYRAZOL 4 ONE O (OXIRANYLMETHYL)OXIME; 1 PHENYL 1H INDENO[1,2 C]PYRAZOL 4 ONE O [(2 HYDROXY 3 (ISOPROPYLAMINO)PROPYL]OXIME; 1 PHENYL 1H INDENO[1,2 C]PYRAZOL 4 ONE O [(3 N BUTYLAMINO) 2 HYDROXYPROPYL]OXIME; 2 (N' METHYLHYDRAZINOMETHYLENE)INDANE 1,3 DIONE; 2 (N' PHENYLHYDRAZINOMETHYLENE)INDANE 1,3 DIONE; ALIPHATIC AMINE; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; EPICHLOROHYDRIN; ETHER DERIVATIVE; OXIME DERIVATIVE; PROPRANOLOL; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG; 1-PHENYL-1H-INDENO(1,2-C)PYRAZOL-4-ONE O-((3-N-BUTYLAMINO)-2-HYDROXYPROPYL)OXIME; BETA 1 ADRENERGIC RECEPTOR; ESTER; OXIME;

ANTI ADRENERGIC ACTION; ARTICLE; BETA 1 ADRENERGIC BLOCKING ACTIVITY; BETA ADRENERGIC STIMULATION; COMPETITIVE INHIBITION; CONTROLLED STUDY; CORONARY ARTERY PRESSURE; DRUG ACTIVITY; DRUG SYNTHESIS; EC50; HEART; HEART CONTRACTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CONTRACTILITY; HEART PERFORMANCE; HEART RATE; IC50; INOTROPISM; INTRINSIC ACTIVITY; MALE; MOLECULE; NONHUMAN; RAT; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; WISTAR RAT;

ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTERS; MALE; MOLECULAR STRUCTURE; OXIMES; PYRAZOLES; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84921683147 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2015.01.037 Document Type: Article

Times cited : (21)

References (37)

1
- 0023839226
- D.H. Barer, J.M. Cruickshank, S.B. Ebraim, J.R.A. Mitchell, B. M. J. 296 (1988) 737-741.
- (1988) B.M.J. , vol.296 , pp. 737-741
- Barer, D.H.¹ Cruickshank, J.M.² Ebraim, S.B.³ Mitchell, J.R.A.⁴

2
- 0024379968
- K.B. Walsh, T.B. Beganisich, R.S. Kass, J. Gen. Physiol. 93 (1989) 841-854.
- (1989) J. Gen. Physiol. , vol.93 , pp. 841-854
- Walsh, K.B.¹ Beganisich, T.B.² Kass, R.S.³

3
- 0034104732
- L. Di Nunno, C. Franchini, A. Scilimati, M.S. Sinicropi, P. Tortorella, Tetrahedron: Asymmetry 11 (2000) 1571-1583.
- (2000) Tetrahedron: Asymmetry , vol.11 , pp. 1571-1583
- Di Nunno, L.¹ Franchini, C.² Scilimati, A.³ Sinicropi, M.S.⁴ Tortorella, P.⁵

4
- 0028147715
- A. Charaf, M. Bouzoubaa, A. Bouzoubaa, M. Blanc, G. Leclerc, Eur. J. Med. Chem. 29 (1994) 69-74.
- (1994) Eur. J. Med. Chem. , vol.29 , pp. 69-74
- Charaf, A.¹ Bouzoubaa, M.² Bouzoubaa, A.³ Blanc, M.⁴ Leclerc, G.⁵

5
- 84886444707
- A.M. Soriano-Ursu ? a, J.G. Trujillo-Ferrara, J. Correa-Basurto, S. Vilar, J. Med. Chem. 56 (2013) 8207-8223.
- (2013) J. Med. Chem. , vol.56 , pp. 8207-8223
- Soriano-Ursua, A.M.¹ Trujillo-Ferrara, J.G.² Correa-Basurto, J.³ Vilar, S.⁴

6
- 0017731606
- G. Leclerc, A. Mann, C.G. Wermuth, J. Med. Chem. 20 (1977) 1657-1662.
- (1977) J. Med. Chem. , vol.20 , pp. 1657-1662
- Leclerc, G.¹ Mann, A.² Wermuth, C.G.³

7
- 0024594564
- B. Jamart-Gregoire, P. Caubere, M. Blanc, J.P. Gnassounou, C. Advenier, J. Med. Chem. 32 (1989) 315-320.
- (1989) J. Med. Chem. , vol.32 , pp. 315-320
- Jamart-Gregoire, B.¹ Caubere, P.² Blanc, M.³ Gnassounou, J.P.⁴ Advenier, C.⁵

8
- 0021148697
- M. Bouzoubaa, G. Leclerc, N. Decker, J. Schwartz, G. Andermann, J. Med. Chem. 27 (1984) 1291-1294.
- (1984) J. Med. Chem. , vol.27 , pp. 1291-1294
- Bouzoubaa, M.¹ Leclerc, G.² Decker, N.³ Schwartz, J.⁴ Andermann, G.⁵

9
- 0021965957
- B. Macchia, A. Balsamo, A. Lapucci, F. Macchia, M.C. Breschi, B. Fantoni, E. Martinotti, J. Med. Chem. 28 (1985) 153-160.
- (1985) J. Med. Chem. , vol.28 , pp. 153-160
- Macchia, B.¹ Balsamo, A.² Lapucci, A.³ Macchia, F.⁴ Breschi, M.C.⁵ Fantoni, B.⁶ Martinotti, E.⁷

10
- 0032492934
- M. Blanc, A. Tamir, S. Aubriot, M.C. Michel, M. Bouzoubaa, G. Leclerc, P. Demenge, J. Med. Chem. 41 (1998) 1613-1618.
- (1998) J. Med. Chem. , vol.41 , pp. 1613-1618
- Blanc, M.¹ Tamir, A.² Aubriot, S.³ Michel, M.C.⁴ Bouzoubaa, M.⁵ Leclerc, G.⁶ Demenge, P.⁷

11
- 0018186058
- A. Fravolini, F. Schiaffella, G. Orzalesi, R. Selleri, I. Volpato, Eur. J. Med. Chem. 13 (1978) 347-350.
- (1978) Eur. J. Med. Chem. , vol.13 , pp. 347-350
- Fravolini, A.¹ Schiaffella, F.² Orzalesi, G.³ Selleri, R.⁴ Volpato, I.⁵

12
- 0016750198
- A. Martani, M. Magli, G. Orzalesi, R. Selleri, Farm. Ed. Sci. 30 (1975) 370-379.
- (1975) Farm. Ed. Sci. , vol.30 , pp. 370-379
- Martani, A.¹ Magli, M.² Orzalesi, G.³ Selleri, R.⁴

13
- 0020458548
- J.J. Baldwin, D.E. McClure, D.M. Gross, M. Williams, J. Med. Chem. 25 (1982) 931-936.
- (1982) J. Med. Chem. , vol.25 , pp. 931-936
- Baldwin, J.J.¹ McClure, D.E.² Gross, D.M.³ Williams, M.⁴

14
- 0021221312
- N. Amlaiky, G. Leclerc, N. Decker, J. Schwartz, Eur. J. Med. Chem. 19 (1984) 341-346.
- (1984) Eur. J. Med. Chem. , vol.19 , pp. 341-346
- Amlaiky, N.¹ Leclerc, G.² Decker, N.³ Schwartz, J.⁴

15
- 0024987402
- P.L. Ferrarini, C. Mori, G. Primofiore, A. Da Settimo, M.C. Breschi, E. Martinotti, P. Nieri, M.A. Ciucci, Eur. J. Med. Chem. 25 (1990) 489-496.
- (1990) Eur. J. Med. Chem. , vol.25 , pp. 489-496
- Ferrarini, P.L.¹ Mori, C.² Primofiore, G.³ Da Settimo, A.⁴ Breschi, M.C.⁵ Martinotti, E.⁶ Nieri, P.⁷ Ciucci, M.A.⁸

16
- 0031470790
- P.L. Ferrarini, C. Mori, M. Badawneh, C. Manera, G. Saccomanni, V. Calderone, R. Scatizzi, P.L. Barili, Eur. J. Med. Chem. 32 (1997) 955-963.
- (1997) Eur. J. Med. Chem. , vol.32 , pp. 955-963
- Ferrarini, P.L.¹ Mori, C.² Badawneh, M.³ Manera, C.⁴ Saccomanni, G.⁵ Calderone, V.⁶ Scatizzi, R.⁷ Barili, P.L.⁸

17
- 0033822808
- P.L. Ferrarini, C. Mori, M. Badawneh, V. Calderone, R. Greco, C. Manera, A. Martinelli, P. Nieri, G. Saccomanni, Eur. J. Med. Chem. 35 (2000) 815-826.
- (2000) Eur. J. Med. Chem. , vol.35 , pp. 815-826
- Ferrarini, P.L.¹ Mori, C.² Badawneh, M.³ Calderone, V.⁴ Greco, R.⁵ Manera, C.⁶ Martinelli, A.⁷ Nieri, P.⁸ Saccomanni, G.⁹

18
- 0027092743
- A. Balsamo, M.C. Breschi, M. Chini, P. Domiano, G. Giannaccini, A. Lucacchini, B. Macchia, M. Macchia, C. Manera, A. Martinelli, C. Martini, E. Martinotti, P. Nieri, A. Rossello, Eur. J. Med. Chem. 27 (1992) 751-764.
- (1992) Eur. J. Med. Chem. , vol.27 , pp. 751-764
- Balsamo, A.¹ Breschi, M.C.² Chini, M.³ Domiano, P.⁴ Giannaccini, G.⁵ Lucacchini, A.⁶ Macchia, B.⁷ Macchia, M.⁸ Manera, C.⁹ Martinelli, A.¹⁰ Martini, C.¹¹ Martinotti, E.¹² Nieri, P.¹³ Rossello, A.¹⁴

19
- 0028334669
- B. Macchia, A. Balsamo, M.C. Breschi, G. Chiellini, M. Macchia, A. Martinelli, C. Martini, C. Nardini, S. Nencetti, A. Rossello, R. Scatizzi, J. Med. Chem. 37 (1994) 1518-1525.
- (1994) J. Med. Chem. , vol.37 , pp. 1518-1525
- Macchia, B.¹ Balsamo, A.² Breschi, M.C.³ Chiellini, G.⁴ Macchia, M.⁵ Martinelli, A.⁶ Martini, C.⁷ Nardini, C.⁸ Nencetti, S.⁹ Rossello, A.¹⁰ Scatizzi, R.¹¹

20
- 0028585863
- A. Balsamo, D. Gentili, A. Lapucci, M. Macchia, A. Martinelli, E. Orlandini, Farmaco 49 (1994) 759-766.
- (1994) Farmaco , vol.49 , pp. 759-766
- Balsamo, A.¹ Gentili, D.² Lapucci, A.³ Macchia, M.⁴ Martinelli, A.⁵ Orlandini, E.⁶

21
- 0029046852
- A. Balsamo, A. Lapucci, B. Macchia, M. Macchia, E. Orlandini, A. Rossello, Farmaco 50 (1995) 239-243.
- (1995) Farmaco , vol.50 , pp. 239-243
- Balsamo, A.¹ Lapucci, A.² Macchia, B.³ Macchia, M.⁴ Orlandini, E.⁵ Rossello, A.⁶

22
- 0029163186
- D. Gentili, A. Lapucci, B. Macchia, M. Macchia, A. Martinelli, S. Nencetti, E. Orlandini, G. Ferni, M. Pinza, Farmaco 50 (1995) 519-526.
- (1995) Farmaco , vol.50 , pp. 519-526
- Gentili, D.¹ Lapucci, A.² Macchia, B.³ Macchia, M.⁴ Martinelli, A.⁵ Nencetti, S.⁶ Orlandini, E.⁷ Ferni, G.⁸ Pinza, M.⁹

23
- 0022970112
- S. Rakhit, M. Bouzoubaa, G. Leclerc, J.M. Leger, A. Carpy, Eur. J. Med. Chem. 21 (1986) 411-416.
- (1986) Eur. J. Med. Chem. , vol.21 , pp. 411-416
- Rakhit, S.¹ Bouzoubaa, M.² Leclerc, G.³ Leger, J.M.⁴ Carpy, A.⁵

24
- 84986524472
- P. Schenone, L. Mosti, G. Menozzi, J. Heterocycl. Chem. 19 (1982) 1355-1361.
- (1982) J. Heterocycl. Chem. , vol.19 , pp. 1355-1361
- Schenone, P.¹ Mosti, L.² Menozzi, G.³

25
- 0016683628
- J. Coltart, E.L. Alderman, S.C. Robison, D.C. Harrison, Br. Heart J. 37 (1975) 357-364.
- (1975) Br. Heart J. , vol.37 , pp. 357-364
- Coltart, J.¹ Alderman, E.L.² Robison, S.C.³ Harrison, D.C.⁴

26
- 0018976421
- M. Briley, I. Cavero, S.Z. Langer, A.G. Roach, Br. J. Pharmacol. 69 (1980) 669-673.
- (1980) Br. J. Pharmacol. , vol.69 , pp. 669-673
- Briley, M.¹ Cavero, I.² Langer, S.Z.³ Roach, A.G.⁴

27
- 47349129993
- B. Tota, T. Angelone, R. Mazza, M.C. Cerra, Curr. Med. Chem. 15 (2008) 1444-1451.
- (2008) Curr. Med. Chem. , vol.15 , pp. 1444-1451
- Tota, B.¹ Angelone, T.² Mazza, R.³ Cerra, M.C.⁴

28
- 84921626855
- Q. Ma, A.Y.H. Lu, Pharmacol. Rev. 63 (2011) 2437-2459.
- (2011) Pharmacol. Rev. , vol.63 , pp. 2437-2459
- Ma, Q.¹ Lu, A.Y.H.²

29
- 84863096615
- S.B. Wachter, E.M. Gilbert, Cardiology 122 (2012) 104-112.
- (2012) Cardiology , vol.122 , pp. 104-112
- Wachter, S.B.¹ Gilbert, E.M.²

30
- 84889668219
- V. Barrese, M. Taglialatela, Front. Physiol. 14 (2013) 323.
- (2013) Front. Physiol. , vol.14 , pp. 323
- Barrese, V.¹ Taglialatela, M.²

31
- 0029665961
- C. Gauthier, G. Tavernier, F. Charpentier, D. Langin, H. Le Marec, J. Clin. Investig. 98 (1996) 556-562.
- (1996) J. Clin. Investig. , vol.98 , pp. 556-562
- Gauthier, C.¹ Tavernier, G.² Charpentier, F.³ Langin, D.⁴ Le Marec, H.⁵

32
- 0142026961
- G. Tavernier, G. Toumaniantz, M. Erfanian, M.F. Heymann, K. Laurent, D. Langin, C. Gauthier, Cardiovasc. Res. 59 (2003) 288-296.
- (2003) Cardiovasc. Res. , vol.59 , pp. 288-296
- Tavernier, G.¹ Toumaniantz, G.² Erfanian, M.³ Heymann, M.F.⁴ Laurent, K.⁵ Langin, D.⁶ Gauthier, C.⁷

33
- 44649133431
- T. Angelone, E. Filice, A.M. Quintieri, S. Imbrogno, A. Recchia, E. Puler-A, C. Mannarino, D. Pellegrino, M.C. Cerra, Acta Physiol. (Oxf) 193 (2008) 229-239.
- (2008) Acta Physiol. (Oxf , vol.193 , pp. 229-239
- Angelone, T.¹ Filice, E.² Quintieri, A.M.³ Imbrogno, S.⁴ Recchia, A.⁵ Pulera, E.⁶ Mannarino, C.⁷ Pellegrino, D.⁸ Cerra, M.C.⁹

34
- 0032189129
- C. Gauthier, V. Leblais, L. Kobzik, J.N. Trochu, N. Khandoudi, A. Bril, J.L. Balligand, H. Le Marec, J. Clin. Investig. 102 (1998) 1377-1384.
- (1998) J. Clin. Investig. , vol.102 , pp. 1377-1384
- Gauthier, C.¹ Leblais, V.² Kobzik, L.³ Trochu, J.N.⁴ Khandoudi, N.⁵ Bril, A.⁶ Balligand, J.L.⁷ Le Marec, H.⁸

35
- 8444219757
- F. Campagna, F. Palluotto, A. Carotti, E. Maciocco, Il Farm. 59 (2004) 849-856.
- (2004) Il Farm. , vol.59 , pp. 849-856
- Campagna, F.¹ Palluotto, F.² Carotti, A.³ Maciocco, E.⁴

36
- 84921628545
- P.L. Ferrarini, C. Mori, M. Badawneh, V. Calderone, R. Greco, C. Manera, A. Martinelli, A. Nieri, G. Saccomanni, Eur. J. Chem. 35 (1999) 315-826.
- (1999) Eur. J. Chem. , vol.35 , pp. 315-826
- Ferrarini, P.L.¹ Mori, C.² Badawneh, M.³ Calderone, V.⁴ Greco, R.⁵ Manera, C.⁶ Martinelli, A.⁷ Nieri, A.⁸ Saccomanni, G.⁹

37
- 0027281255
- V.K. Tandon, A. Chandra, P.R. Dua, R.C. Srimal, Arckiv Pharm. 326 (1992) 221-225.
- (1992) Arckiv Pharm. , vol.326 , pp. 221-225
- Tandon, V.K.¹ Chandra, A.² Dua, P.R.³ Srimal, R.C.⁴

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