Synthesis and adrenergic activity of a new series of N-aryl dicyclopropyl ketone oxime ethers: SAR and stereochemical aspects

Journal of Medicinal Chemistry

Volumn 41, Issue 10, 1998, Pages 1613-1618

  Blanc, Madeleine ^a   Tamir, Abderrafii ^a   Aubriot, Silvère ^a   Michel, Marie Claude ^b   Bouzoubaa, Mohamed ^a   Leclerc, Gérard ^a   Demenge, Pierre ^b  

^a UNIV GRENOBLE ALPES   (France)

^b University of Casablanca   (Morocco)

Author keywords

[No Author keywords available]

Indexed keywords

O [3 (4 BUTYLAMINOPHENYL) 2 HYDROXYPROPYL]DICYCLOPROPYL KETONE OXIME; UNCLASSIFIED DRUG;

ADRENERGIC ACTIVITY; ANIMAL TISSUE; ARTICLE; CHRONOTROPISM; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; GUINEA PIG; HEART ATRIUM; HEART VENTRICLE; INOTROPISM; NONHUMAN; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TISSUE HOMOGENATE;

ADRENERGIC AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CYCLOPROPANES; GUINEA PIGS; HEART RATE; LIGANDS; MALE; MYOCARDIAL CONTRACTION; OPTICAL ROTATION; OXIMES; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032492934     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970338c     Document Type: Article

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