The participation of cortical amygdala in innate, odour-driven behaviour

Nature

Volumn 515, Issue 7526, 2014, Pages 269-273

  Root, Cory M ^a   Denny, Christine A ^b   Hen, René ^b   Axel, Richard ^a  

^a Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; HALORHODOPSIN; ION CHANNEL; PROTEIN C FOS;

ANATOMY; NEUROLOGY; ODOR; OLFACTORY CUE; PHYSIOLOGICAL RESPONSE; STEREOTYPIC BEHAVIOR;

ADULT; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; APPETITE; ARTICLE; AVERSIVE BEHAVIOR; AVOIDANCE BEHAVIOR; CONNECTOME; CONTROLLED STUDY; CORTICAL AMYGDALA; ENTORHINAL CORTEX; HYPERPOLARIZATION; LOCOMOTION; LOXP SITE; MEDIAL AMYGDALA; MOUSE; NONHUMAN; ODOR; OLFACTORY BULB; OLFACTORY CORTEX; OLFACTORY DISCRIMINATION; OLFACTORY NUCLEUS; OLFACTORY RECEPTOR; OPTOGENETICS; PHOTOACTIVATION; PHOTOSTIMULATION; PRIORITY JOURNAL; PROMOTER REGION; PYRIFORM CORTEX; SMELLING; SOCIAL BEHAVIOR; STATE DEPENDENT LEARNING; STEREOTYPY; STIMULUS RESPONSE; SYNAPTIC TRANSMISSION; AMYGDALOID NUCLEUS; ANALYSIS; ANIMAL; BEHAVIOR; CYTOLOGY; LEARNING; NERVE CELL; OLFACTORY SYSTEM; PHYSIOLOGY;

ANIMALIA;

AMYGDALA; ANIMALS; BEHAVIOR; LEARNING; MICE; NEURONS; ODORS; OLFACTORY BULB; OLFACTORY PATHWAYS; OLFACTORY PERCEPTION;

EID: 84921529481     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13897     Document Type: Article

References (34)

1. Sosulski, D. L., Bloom, M. L., Cutforth, T., Axel, R. & Datta, S. R. Distinct representations of olfactory information in different cortical centres. Nature 472, 213-216 (2011).
2. Miyamichi, K. et al. Cortical representations of olfactory input by trans-synaptic tracing. Nature 472, 191-196 (2011).
3. Ghosh, S. et al. Sensory maps in the olfactory cortex defined by long-range viral tracing of single neurons. Nature 472, 217-220 (2011).
4. Stowers, L. & Logan, D. W. Olfactory mechanisms of stereotyped behavior: on the scent of specialized circuits. Curr. Opin. Neurobiol. 20, 274-280 (2010).
5. Chamero, P. et al. Identification of protein pheromones that promote aggressive behaviour. Nature 450, 899-902 (2007).
6. Nodari, F. et al. Sulfated steroids as natural ligands of mouse pheromone-sensing neurons. J. Neurosci. 28, 6407-6418 (2008).
7. Kobayakawa, K. et al. Innate versus learned odour processing in the mouse olfactory bulb. Nature 450, 503-508 (2007).
8. Dewan, A., Pacifico, R., Zhan, R., Rinberg, D. & Bozza, T. Non-redundant coding of aversive odours in the main olfactory pathway. Nature 497, 486-489 (2013).
9. Li, Q. et al. Synchronous evolution of an odor biosynthesis pathway and behavioral response. Curr. Biol. 23, 11-20 (2013).
10. Buck, L. & Axel, R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65, 175-187 (1991).
11. Godfrey, P. A., Malnic, B. & Buck, L. B. The mouse olfactory receptor gene family. Proc. Natl Acad. Sci. USA 101, 2156-2161 (2004).
12. Zhang, X. & Firestein, S. The olfactory receptor gene superfamily of the mouse. Nature Neurosci. 5, 124-133 (2002).
13. Ressler, K. J., Sullivan, S. L.&Buck, L. B. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitopemap in the olfactorybulb. Cell 79, 1245-1255 (1994).
14. Mombaerts, P. et al. Visualizing an olfactory sensorymap. Cell 87, 675-686 (1996).
15. Vassar, R. et al. Topographic organization of sensory projections to the olfactory bulb. Cell 79, 981-991 (1994).
16. Rubin, B. D. & Katz, L. C. Optical imaging of odorant representations in the mammalian olfactory bulb. Neuron 23, 499-511 (1999).
17. Gradinaru, V., Thompson, K. R. & Deisseroth, K. eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications. Brain Cell Biol. 36, 129-139 (2008).
18. Tye, K. M. et al. Amygdala circuitrymediating reversible andbidirectional control of anxiety. Nature 471, 358-362 (2011).
19. Link, W. et al. Somatodendritic expression of an immediate early gene is regulated by synaptic activity. Proc. Natl Acad. Sci. USA 92, 5734-5738 (1995).
20. Boyden, E. S., Zhang, F., Bamberg, E., Nagel, G. & Deisseroth, K. Millisecondtimescale, genetically targeted optical control of neural activity. Nature Neurosci. 8, 1263-1268 (2005).
21. Denny, C. A. et al. Hippocampal memory traces are differentially modulated by experience, time, and adult neurogenesis. Neuron 83, 189-201 (2014).
22. Choi, G. B. et al. Driving opposing behaviors with ensembles of piriform neurons. Cell 146, 1003-1014 (2011).
23. Stettler, D. D. & Axel, R. Representations of odor in the piriform cortex. Neuron 63, 854-864 (2009).
24. Poo, C. & Isaacson, J. S. Odor representations in olfactory cortex: "sparse" coding, global inhibition, and oscillations. Neuron 62, 850-861 (2009).
25. Illig, K. R. & Haberly, L. B. Odor-evoked activity is spatially distributed in piriform cortex. J. Comp. Neurol. 457, 361-373 (2003).
26. Schwabe, K., Ebert, U. & Loscher, W. The central piriform cortex: anatomical connections and anticonvulsant effect of GABA elevation in the kindling model. Neuroscience 126, 727-741 (2004).
27. Tonegawa, S.&McHugh, T. J. The ins and outs of hippocampal circuits. Neuron 57, 175-177 (2008).
28. Tanaka, N. K., Tanimoto, H. & Ito, K. Neuronal assemblies of the Drosophila mushroom body. J. Comp. Neurol. 508, 711-755 (2008).
29. Louise, E. M., Vet, J. C. V. L., Heymans, M. & Meelis, E. An airflow olfactometer for measuring olfactory responses of hymenopterous parasitoids and other small insects. Physiol. Entomol. 8, 97-106 (1983).
30. Faucher, C., Forstreuter, M., Hilker, M. & de Bruyne, M. Behavioral responses of Drosophila to biogenic levels of carbon dioxide depend on life-stage, sex and olfactory context. J. Exp. Biol. 209, 2739-2748 (2006).
31. Semmelhack, J. L. & Wang, J. W. Select Drosophila glomeruli mediate innate olfactory attraction and aversion. Nature 459, 218-223 (2009).
32. Vo-Dinh, T. Biomedical Photonics Handbook Ch. 2, 37 (CRC, 2003).
33. Yizhar, O., Fenno, L. E., Davidson, T. J., Mogri, M. & Deisseroth, K. Optogenetics in neural systems. Neuron 71, 9-34 (2011).
34. Aravanis, A. M. et al. An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. J. Neural Eng. 4, S143-S156 (2007).