Identification of potential pancreatic cancer serum markers: Increased sialyl-Lewis X on ceruloplasmin

Clinica Chimica Acta

Volumn 442, Issue , 2015, Pages 56-62

  Balmaña, Meritxell ^a   Sarrats, Ariadna ^a   Llop, Esther ^a   Barrabés, Sílvia ^a   Saldova, Radka ^b   Ferri, María José ^c   Figueras, Joan ^d   Fort, Esther ^c   de Llorens, Rafael ^a   Rudd, Pauline M ^b   Peracaula, Rosa ^a  

^a UNIVERSITY OF GIRONA   (Spain)

^b NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH AND TRAINING   (Ireland)

^c Dr Josep Trueta University Hospital   (Spain)

^d HOSPITAL JOSEP TRUETA   (Spain)

Author keywords

Acute phase proteins; Biomarker; Ceruloplasmin; Pancreatic cancer; Pancreatitis; Sialyl Lewis X

Indexed keywords

ACUTE PHASE PROTEIN; CERULOPLASMIN; CERULOPLASMIN ANTIBODY; EPITOPE; PROTEIN ANTIBODY; SIALYL LEWIS X ANTIGEN; TRYPSIN; TUMOR MARKER; UNCLASSIFIED DRUG; 5-ACETYLNEURAMINYL-(2-3)-GALACTOSYL-(1-4)-(FUCOPYRANOSYL-(1-3))-N-ACETYLGLUCOSAMINE; GLYCOPROTEIN; OLIGOSACCHARIDE; POLYSACCHARIDE;

ADULT; AGED; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; BLOOD ANALYSIS; CHRONIC PANCREATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROPHORESIS; ELECTROSPRAY; FEMALE; HUMAN; HUMAN CELL; IMMUNODETECTION; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; MALE; PANCREAS ADENOCARCINOMA; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN SECRETION; PROTEIN STRUCTURE; QUADRUPOLE MASS SPECTROMETRY; SEQUENCE ANALYSIS; WESTERN BLOTTING; ADENOCARCINOMA; BLOOD; CASE CONTROL STUDY; CHEMISTRY; GENE EXPRESSION REGULATION; METABOLISM; MIDDLE AGED; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE;

ADENOCARCINOMA; ADULT; AGED; BIOMARKERS, TUMOR; CASE-CONTROL STUDIES; CELL LINE, TUMOR; CERULOPLASMIN; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; MALE; MIDDLE AGED; OLIGOSACCHARIDES; PANCREATIC NEOPLASMS; PANCREATITIS, CHRONIC; POLYSACCHARIDES;

EID: 84921524523     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2015.01.007     Document Type: Article

References (33)

1. Siegel R., Ma J., Zou Z., Jemal A. Cancer statistics, 2014. CA Cancer J Clin 2014, 64:9-29.
2. Ferlay J., Steliarova-Foucher E., Lortet-Tieulent J., et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012. Eur J Cancer 2013, 49:1374-1403.
3. Grote T., Logsdon C.D. Progress on molecular markers of pancreatic cancer. Curr Opin Gastroenterol 2007, 23:508-514.
4. Misek D.E., Patwa T.H., Lubman D.M., Simeone D.M. Early detection and biomarkers in pancreatic cancer. J Natl Compr Cancer Netw 2007, 5:1034-1041.
5. Glycosylation Changes in Cancer. Essentials of Glycobiology 2009, Cold Spring Harbour Laboratory Press, New Yord. 2nd ed. A.K.R. Varki, B.P. Toole (Eds.).
6. Hosono J., Narita T., Kimura N., et al. Involvement of adhesion molecules in metastasis of SW1990, human pancreatic cancer cells. J Surg Oncol 1998, 67:77-84.
7. Peracaula R., Tabares G., Lopez-Ferrer A., Brossmer R., de Bolos C., de Llorens R. Role of sialyltransferases involved in the biosynthesis of Lewis antigens in human pancreatic tumour cells. Glycoconj J 2005, 22:135-144.
8. Kim Y.S., Itzkowitz S.H., Yuan M., et al. Lex and Ley antigen expression in human pancreatic cancer. Cancer Res 1988, 48:475-482.
9. Satomura Y., Sawabu N., Takemori Y., et al. Expression of various sialylated carbohydrate antigens in malignant and nonmalignant pancreatic tissues. Pancreas 1991, 6:448-458.
10. Sinn H.P., Brown S.A., Oberle E., Thompson J.S. Analysis of the Lewisx epitope in human pancreas and pancreatic adenocarcinomas. Int J Pancreatol 1992, 11:125-135.
11. Li C., Simeone D.M., Brenner D.E., et al. Pancreatic cancer serum detection using a lectin/glyco-antibody array method. J Proteome Res 2009, 8:483-492.
12. Sawada T., Ho J.J., Chung Y.S., Sowa M., Kim Y.S. E-selectin binding by pancreatic tumor cells is inhibited by cancer sera. Int J Cancer 1994, 57:901-907.
13. Zhao J., Patwa T.H., Qiu W., et al. Glycoprotein microarrays with multi-lectin detection: unique lectin binding patterns as a tool for classifying normal, chronic pancreatitis and pancreatic cancer sera. J Proteome Res 2007, 6:1864-1874.
14. Sarrats A., Saldova R., Pla E., et al. Glycosylation of liver acute-phase proteins in pancreatic cancer and chronic pancreatitis. Proteomics Clin Appl 2010, 4:432-448.
15. Kunapuli S.P., Singh H., Singh P., Kumar A. Ceruloplasmin gene expression in human cancer cells. Life Sci 1987, 40:2225-2228.
16. Lowndes S.A., Harris A.L. Copper chelation as an antiangiogenic therapy. Oncol Res 2004, 14:529-539.
17. Harazono A., Kawasaki N., Itoh S., et al. Site-specific N-glycosylation analysis of human plasma ceruloplasmin using liquid chromatography with electrospray ionization tandem mass spectrometry. Anal Biochem 2006, 348:259-268.
18. Harazono A., Kawasaki N., Itoh S., et al. Simultaneous glycosylation analysis of human serum glycoproteins by high-performance liquid chromatography/tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2008, 869:20-30.
19. Royle L., Radcliffe C.M., Dwek R.A., Rudd P.M. Detailed structural analysis of N-glycans released from glycoproteins in SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions. Methods Mol Biol 2006, 347:125-143.
20. Bigge J.C., Patel T.P., Bruce J.A., Goulding P.N., Charles S.M., Parekh R.B. Nonselective and efficient fluorescent labeling of glycans using 2-amino benzamide and anthranilic acid. Anal Biochem 1995, 230:229-238.
21. Pu X.P., Iwamoto A., Nishimura H., Nagasawa S. Purification and characterization of a novel substrate for plasma kallikrein (PK-120) in human plasma. Biochim Biophys Acta 1994, 1208:338-343.
22. Blanchong C.A., Chung E.K., Rupert K.L., et al. Genetic, structural and functional diversities of human complement components C4A and C4B and their mouse homologues, Slp and C4. Int Immunopharmacol 2001, 1:365-392.
23. Abd-el-Fattah M., Scherer R., Fouad F.M., Ruhenstroth-Bauer G. Kinetics of the acute-phase reaction in rats after tumor transplantation. Cancer Res 1981, 41:2548-2555.
24. Ros-Bullon M.R., Sanchez-Pedreno P., Martinez-Liarte J.H. Serum ceruloplasmin in melanoma patients. Anticancer Res 2001, 21:629-632.
25. Senra Varela A., Lopez Saez J.J., Quintela Senra D. Serum ceruloplasmin as a diagnostic marker of cancer. Cancer Lett 1997, 121:139-145.
26. Liu Y., He J., Li C., et al. Identification and confirmation of biomarkers using an integrated platform for quantitative analysis of glycoproteins and their glycosylations. J Proteome Res 2010, 9:798-805.
27. Mann B., Madera M., Klouckova I., et al. A quantitative investigation of fucosylated serum glycoproteins with application to esophageal adenocarcinoma. Electrophoresis 2010, 31:1833-1841.
28. Hansen J.E., Iversen J., Lihme A., Bog-Hansen T.C. Acute phase reaction, heterogeneity, and microheterogeneity of serum proteins as nonspecific tumor markers in lung cancer. Cancer 1987, 60:1630-1635.
29. Heo S.H., Lee S.J., Ryoo H.M., Park J.Y., Cho J.Y. Identification of putative serum glycoprotein biomarkers for human lung adenocarcinoma by multilectin affinity chromatography and LC-MS/MS. Proteomics 2007, 7:4292-4302.
30. Mohamed E., Abdul-Rahman P.S., Doustjalali S.R., et al. Lectin-based electrophoretic analysis of the expression of the 35kDa inter-alpha-trypsin inhibitor heavy chain H4 fragment in sera of patients with five different malignancies. Electrophoresis 2008, 29:2645-2650.
31. Qiu Y., Patwa T.H., Xu L., et al. Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectin glycoarray and lectin blot. J Proteome Res 2008, 7:1693-1703.
32. Dempsey E., Rudd P.M. Acute phase glycoproteins: bystanders or participants in carcinogenesis?. Ann N Y Acad Sci 2012, 1253:122-132.
33. Perez-Garay M., Arteta B., Pages L., et al. alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo. PLoS One 2010, 5.