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Volumn 23, Issue 5, 2007, Pages 508-514

Progress on molecular markers of pancreatic cancer

Author keywords

Biomarker; Molecular marker; Pancreatic cancer

Indexed keywords

ACTZ 14011; BIOLOGICAL MARKER; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; INDIUM 111; MOLECULAR MARKER; UNCLASSIFIED DRUG;

EID: 34548401651     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOG.0b013e3282ba5724     Document Type: Review
Times cited : (45)

References (43)
  • 1
    • 33747065800 scopus 로고    scopus 로고
    • Cancer biomarkers: A systems approach
    • This excellent review discusses the various applications of biomarkers and their different requirements
    • Hartwell L, Mankoff D, Paulovich A, et al. Cancer biomarkers: a systems approach. Nat Biotechnol 2006; 24:905-908. This excellent review discusses the various applications of biomarkers and their different requirements.
    • (2006) Nat Biotechnol , vol.24 , pp. 905-908
    • Hartwell, L.1    Mankoff, D.2    Paulovich, A.3
  • 2
    • 26944496117 scopus 로고    scopus 로고
    • REporting recommendations for tumor MARKer prognostic studies (REMARK)
    • McShane LM, Altman DG, Sauerbrei W, et al. REporting recommendations for tumor MARKer prognostic studies (REMARK). Nat Clin Pract Oncol 2005; 2:416-422.
    • (2005) Nat Clin Pract Oncol , vol.2 , pp. 416-422
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3
  • 3
    • 33646550512 scopus 로고    scopus 로고
    • Molecular biomarkers: Their increasing role in the diagnosis, characterization, and therapy guidance in pancreatic cancer
    • This comprehensive review provides an overview about the same topic as the current article
    • Jimeno A, Hidalgo M. Molecular biomarkers: their increasing role in the diagnosis, characterization, and therapy guidance in pancreatic cancer. Mol Cancer Ther 2006; 5:787-796. This comprehensive review provides an overview about the same topic as the current article.
    • (2006) Mol Cancer Ther , vol.5 , pp. 787-796
    • Jimeno, A.1    Hidalgo, M.2
  • 4
    • 33644815924 scopus 로고    scopus 로고
    • Gold DV, Modrak DE, Ying Z, et al. New MUC1 serum immunoassay differentiates pancreatic cancer from pancreatitis. J Clin Oncol 2006; 24:252-258. This article reports studies with an improved immunoassay for MUC1 that shows promising results and supports the idea that biomarkers better than CA19-9 can be developed.
    • Gold DV, Modrak DE, Ying Z, et al. New MUC1 serum immunoassay differentiates pancreatic cancer from pancreatitis. J Clin Oncol 2006; 24:252-258. This article reports studies with an improved immunoassay for MUC1 that shows promising results and supports the idea that biomarkers better than CA19-9 can be developed.
  • 5
    • 34248187583 scopus 로고    scopus 로고
    • Simeone DM, Ji B, Banerjee M, et al. CEACAM1, a novel serum biomarker for pancreatic cancer. Pancreas 2007; 34:436-443. This article describes the characterization of CEACAM1 as a biomarker with some promise. This molecule was originally discovered as overexpressed in pancreatic cancer during analysis of gene expression with microarrays and is an example of moving from gene discovery to practical application.
    • Simeone DM, Ji B, Banerjee M, et al. CEACAM1, a novel serum biomarker for pancreatic cancer. Pancreas 2007; 34:436-443. This article describes the characterization of CEACAM1 as a biomarker with some promise. This molecule was originally discovered as overexpressed in pancreatic cancer during analysis of gene expression with microarrays and is an example of moving from gene discovery to practical application.
  • 6
    • 31544450588 scopus 로고    scopus 로고
    • Koopmann J, Rosenzweig CN, Zhang Z, et al. Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9. Clin Cancer Res 2006; 12:442-446. The authors tested a panel of five markers and report the results thoroughly, unfortunately none proved to be superior to CA19-9 even in combination.
    • Koopmann J, Rosenzweig CN, Zhang Z, et al. Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9. Clin Cancer Res 2006; 12:442-446. The authors tested a panel of five markers and report the results thoroughly, unfortunately none proved to be superior to CA19-9 even in combination.
  • 7
    • 33847120804 scopus 로고    scopus 로고
    • Identification of potential markers for the detection of pancreatic cancer through comparative serum protein expression profiling
    • This study took a proteomic approach and found new potential markers and validated two of them with a commercially available ELISA
    • Ehmann M, Felix K, Hartmann D, et al. Identification of potential markers for the detection of pancreatic cancer through comparative serum protein expression profiling. Pancreas 2007; 34:205-214. This study took a proteomic approach and found new potential markers and validated two of them with a commercially available ELISA.
    • (2007) Pancreas , vol.34 , pp. 205-214
    • Ehmann, M.1    Felix, K.2    Hartmann, D.3
  • 8
    • 33748932541 scopus 로고    scopus 로고
    • Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4
    • Takehara A, Eguchi H, Ohigashi H, et al. Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4. Cancer Sci 2006; 97:1191-1197.
    • (2006) Cancer Sci , vol.97 , pp. 1191-1197
    • Takehara, A.1    Eguchi, H.2    Ohigashi, H.3
  • 9
    • 33645680173 scopus 로고    scopus 로고
    • Overexpression and elevated serum levels of phosphoglycerate kinase 1 in pancreatic ductal adenocarcinoma
    • Hwang TL, Liang Y, Chien KY, Yu JS. Overexpression and elevated serum levels of phosphoglycerate kinase 1 in pancreatic ductal adenocarcinoma. Proteomics 2006; 6:2259-2272.
    • (2006) Proteomics , vol.6 , pp. 2259-2272
    • Hwang, T.L.1    Liang, Y.2    Chien, K.Y.3    Yu, J.S.4
  • 10
    • 33748319460 scopus 로고    scopus 로고
    • Significance of serum receptor-binding cancer antigen (RCAS1) in pancreatic cancer and benign pancreatobiliary diseases
    • Özkan H, Akar T, Koklu S, Coban S. Significance of serum receptor-binding cancer antigen (RCAS1) in pancreatic cancer and benign pancreatobiliary diseases. Pancreatology 2006; 6:268-272.
    • (2006) Pancreatology , vol.6 , pp. 268-272
    • Özkan, H.1    Akar, T.2    Koklu, S.3    Coban, S.4
  • 11
    • 33646530977 scopus 로고    scopus 로고
    • Serological immune response to cancer testis antigens in patients with pancreatic cancer
    • Wadle A, Kubuschok B, Imig J, et al. Serological immune response to cancer testis antigens in patients with pancreatic cancer. Int J Cancer 2006; 119:117-125.
    • (2006) Int J Cancer , vol.119 , pp. 117-125
    • Wadle, A.1    Kubuschok, B.2    Imig, J.3
  • 12
    • 33646909090 scopus 로고    scopus 로고
    • Quantification of fragments of human serum inter-alpha-trypsin inhibitor heavy chain 4 by a surface-enhanced laser desorption/ionization-based immunoassay
    • Song J, Patel M, Rosenzweig CN, et al. Quantification of fragments of human serum inter-alpha-trypsin inhibitor heavy chain 4 by a surface-enhanced laser desorption/ionization-based immunoassay. Clin Chem 2006; 52:1045-1053.
    • (2006) Clin Chem , vol.52 , pp. 1045-1053
    • Song, J.1    Patel, M.2    Rosenzweig, C.N.3
  • 13
    • 33645056682 scopus 로고    scopus 로고
    • Fibrinogen gamma overexpression in pancreatic cancer identified by large-scale proteomic analysis of serum samples
    • Bloomston M, Zhou JX, Rosemurgy AS, et al. Fibrinogen gamma overexpression in pancreatic cancer identified by large-scale proteomic analysis of serum samples. Cancer Res 2006; 66:2592-2599.
    • (2006) Cancer Res , vol.66 , pp. 2592-2599
    • Bloomston, M.1    Zhou, J.X.2    Rosemurgy, A.S.3
  • 14
    • 33646044427 scopus 로고    scopus 로고
    • Low correspondence between K-ras mutations in pancreatic cancer tissue and detection of K-ras mutations in circulating DNA
    • The authors could not detect any K-ras mutation in circulating DNA from pancreatic cancer patients
    • Marchese R, Muleti A, Pasqualetti P, et al. Low correspondence between K-ras mutations in pancreatic cancer tissue and detection of K-ras mutations in circulating DNA. Pancreas 2006; 32:171-177. The authors could not detect any K-ras mutation in circulating DNA from pancreatic cancer patients.
    • (2006) Pancreas , vol.32 , pp. 171-177
    • Marchese, R.1    Muleti, A.2    Pasqualetti, P.3
  • 15
    • 33644926984 scopus 로고    scopus 로고
    • Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer
    • This publication reports an interesting and promising approach even though sensitivity and specificity are not high enough for a single marker
    • Ishizone S, Yamauchi K, Kawa S, et al. Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer. Cancer Sci 2006; 97:119-126. This publication reports an interesting and promising approach even though sensitivity and specificity are not high enough for a single marker.
    • (2006) Cancer Sci , vol.97 , pp. 119-126
    • Ishizone, S.1    Yamauchi, K.2    Kawa, S.3
  • 16
    • 33846934267 scopus 로고    scopus 로고
    • Detection of disseminated pancreatic cells by amplification of cytokeratin-19 with quantitative RT-PCR in blood, bone marrow and peritoneal lavage of pancreatic carcinoma patients
    • Hoffmann K, Kerner C, Wilfert W, et al. Detection of disseminated pancreatic cells by amplification of cytokeratin-19 with quantitative RT-PCR in blood, bone marrow and peritoneal lavage of pancreatic carcinoma patients. World J Gastroenterol 2007; 13:257-263.
    • (2007) World J Gastroenterol , vol.13 , pp. 257-263
    • Hoffmann, K.1    Kerner, C.2    Wilfert, W.3
  • 17
    • 33646343959 scopus 로고    scopus 로고
    • Fucosylated haptoglobin is a novel marker for pancreatic cancer: A detailed analysis of the oligosaccharide structure and a possible mechanism for fucosylation
    • Okuyama N, Ide Y, Nakano M, et al. Fucosylated haptoglobin is a novel marker for pancreatic cancer: a detailed analysis of the oligosaccharide structure and a possible mechanism for fucosylation. Int J Cancer 2006; 118:2803-2808.
    • (2006) Int J Cancer , vol.118 , pp. 2803-2808
    • Okuyama, N.1    Ide, Y.2    Nakano, M.3
  • 18
    • 33748809567 scopus 로고    scopus 로고
    • Screening of glycosylation patterns in serum using natural glycoprotein microarrays and multilectin fluorescence detection
    • This proof of principle study seems to be a promising new approach to detect glycosylation patterns with a microarray platform
    • Patwa TH, Zhao J, Anderson MA, et al. Screening of glycosylation patterns in serum using natural glycoprotein microarrays and multilectin fluorescence detection. Anal Chem 2006; 78:6411-6421. This proof of principle study seems to be a promising new approach to detect glycosylation patterns with a microarray platform.
    • (2006) Anal Chem , vol.78 , pp. 6411-6421
    • Patwa, T.H.1    Zhao, J.2    Anderson, M.A.3
  • 19
    • 33947581026 scopus 로고    scopus 로고
    • N-linked glycosylation profiling of pancreatic cancer serum using capillary liquid phase separation coupled with mass spectrometric analysis
    • This article supports the previous one, that glycosylation patterns might be useful as a new type of biomarker
    • Zhao J, Qiu W, Simeone DM, Lubman DM. N-linked glycosylation profiling of pancreatic cancer serum using capillary liquid phase separation coupled with mass spectrometric analysis. J Proteome Res 2007; 6:1126-1138. This article supports the previous one, that glycosylation patterns might be useful as a new type of biomarker.
    • (2007) J Proteome Res , vol.6 , pp. 1126-1138
    • Zhao, J.1    Qiu, W.2    Simeone, D.M.3    Lubman, D.M.4
  • 20
    • 33846595479 scopus 로고    scopus 로고
    • ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer
    • This article provides guidelines for the clinical use of biomarkers in colorectal and pancreatic cancer
    • Locker GY, Hamilton S, Harris J, et al. ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer. J Clin Oncol 2006; 24:5313-5327. This article provides guidelines for the clinical use of biomarkers in colorectal and pancreatic cancer.
    • (2006) J Clin Oncol , vol.24 , pp. 5313-5327
    • Locker, G.Y.1    Hamilton, S.2    Harris, J.3
  • 21
    • 33344473620 scopus 로고    scopus 로고
    • Chang CY, Huang SP, Chiu HM, et al. Low efficacy of serum levels of CA 19-9 in prediction of malignant diseases in asymptomatic population in Taiwan. Hepatogastroenterology 2006; 53:1-4. The authors provided evidence that CA19-9 is not useful as a population screening marker.
    • Chang CY, Huang SP, Chiu HM, et al. Low efficacy of serum levels of CA 19-9 in prediction of malignant diseases in asymptomatic population in Taiwan. Hepatogastroenterology 2006; 53:1-4. The authors provided evidence that CA19-9 is not useful as a population screening marker.
  • 22
    • 33745552215 scopus 로고    scopus 로고
    • Perioperative CA19-9 levels can predict stage and survival in patients with resectable pancreatic adenocarcinoma
    • Ferrone CR, Finkelstein DM, Thayer SP, et al. Perioperative CA19-9 levels can predict stage and survival in patients with resectable pancreatic adenocarcinoma. J Clin Oncol 2006; 24:2897-2902.
    • (2006) J Clin Oncol , vol.24 , pp. 2897-2902
    • Ferrone, C.R.1    Finkelstein, D.M.2    Thayer, S.P.3
  • 23
    • 33748941924 scopus 로고    scopus 로고
    • Value of preoperative serum CA 19-9 levels in predicting resectability for pancreatic cancer
    • Kilic M, Gocmen E, Tez M, et al. Value of preoperative serum CA 19-9 levels in predicting resectability for pancreatic cancer. Can J Surg 2006; 49:241-244.
    • (2006) Can J Surg , vol.49 , pp. 241-244
    • Kilic, M.1    Gocmen, E.2    Tez, M.3
  • 24
    • 33750552959 scopus 로고    scopus 로고
    • Boeck S, Stieber P, Holdenrieder S, et al. Prognostic and therapeutic significance of carbohydrate antigen 19-9 as tumor marker in patients with pancreatic cancer. Oncology 2006; 70:255-264. This review gives a nice summary about recent publications on the role of CA19-9 as a prognostic marker.
    • Boeck S, Stieber P, Holdenrieder S, et al. Prognostic and therapeutic significance of carbohydrate antigen 19-9 as tumor marker in patients with pancreatic cancer. Oncology 2006; 70:255-264. This review gives a nice summary about recent publications on the role of CA19-9 as a prognostic marker.
  • 25
    • 33846649482 scopus 로고    scopus 로고
    • Assessing prognosis in metastatic pancreatic cancer by the serum tumor marker CA 19-9: Pretreatment levels or kinetics during chemotherapy?
    • Boeck S, Schulz C, Stieber P, et al. Assessing prognosis in metastatic pancreatic cancer by the serum tumor marker CA 19-9: pretreatment levels or kinetics during chemotherapy? Onkologie 2007; 30:39-42.
    • (2007) Onkologie , vol.30 , pp. 39-42
    • Boeck, S.1    Schulz, C.2    Stieber, P.3
  • 26
    • 31444447627 scopus 로고    scopus 로고
    • Predictors of cancer in patients with suspected pancreatic malignancy without a tissue diagnosis
    • Tessler DA, Catanzaro A, Velanovich V, et al. Predictors of cancer in patients with suspected pancreatic malignancy without a tissue diagnosis. Am J Surg 2006; 191:191-197.
    • (2006) Am J Surg , vol.191 , pp. 191-197
    • Tessler, D.A.1    Catanzaro, A.2    Velanovich, V.3
  • 27
    • 11144353917 scopus 로고    scopus 로고
    • Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers
    • Koopmann J, Buckhaults P, Brown DA, et al. Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers. Clin Cancer Res 2004; 10:2386-2392.
    • (2004) Clin Cancer Res , vol.10 , pp. 2386-2392
    • Koopmann, J.1    Buckhaults, P.2    Brown, D.A.3
  • 28
    • 31544477679 scopus 로고    scopus 로고
    • DNA methylation alterations in the pancreatic juice of patients with suspected pancreatic disease
    • This solid study might be the basis for the development of a seminal tool in using pancreatic juice for diagnosis
    • Matsubayashi H, Canto M, Sato N, et al. DNA methylation alterations in the pancreatic juice of patients with suspected pancreatic disease. Cancer Res 2006; 66:1208-1217. This solid study might be the basis for the development of a seminal tool in using pancreatic juice for diagnosis.
    • (2006) Cancer Res , vol.66 , pp. 1208-1217
    • Matsubayashi, H.1    Canto, M.2    Sato, N.3
  • 29
    • 33745993022 scopus 로고    scopus 로고
    • Quantitative proteomic profiling of pancreatic cancer juice
    • Chen R, Pan S, Yi EC, et al. Quantitative proteomic profiling of pancreatic cancer juice. Proteomics 2006; 6:3871-3879.
    • (2006) Proteomics , vol.6 , pp. 3871-3879
    • Chen, R.1    Pan, S.2    Yi, E.C.3
  • 30
    • 33845974916 scopus 로고    scopus 로고
    • Comparison of pancreas juice proteins from cancer versus pancreatitis using quantitative proteomic analysis
    • Chen R, Pan S, Cooke K, et al. Comparison of pancreas juice proteins from cancer versus pancreatitis using quantitative proteomic analysis. Pancreas 2007; 34:70-79.
    • (2007) Pancreas , vol.34 , pp. 70-79
    • Chen, R.1    Pan, S.2    Cooke, K.3
  • 31
    • 33646365856 scopus 로고    scopus 로고
    • Proteomic classification of pancreatic adenocarcinoma tissue using protein chip technology
    • This well conducted study shows that proteomic techniques can identify peak panels that help to differentiate cancer from benign tissue
    • Scarlett CJ, Smith RC, Saxby A, et al. Proteomic classification of pancreatic adenocarcinoma tissue using protein chip technology. Gastroenterology 2006; 130:1670-1678. This well conducted study shows that proteomic techniques can identify peak panels that help to differentiate cancer from benign tissue.
    • (2006) Gastroenterology , vol.130 , pp. 1670-1678
    • Scarlett, C.J.1    Smith, R.C.2    Saxby, A.3
  • 32
    • 33646574941 scopus 로고    scopus 로고
    • Tsiambas E, Karameris A, Dervenis C, et al. HER2/neu expression and gene alterations in pancreatic ductal adenocarcinoma: a comparative immunohistochemistry and chromogenic in situ hybridization study based on tissue microarrays and computerized image analysis. JOP 2006; 7:283-294. The authors highlight the importance of correlating gene and protein expression. Also they discuss the benefits of computer assisted analysis of immunohistochemistry.
    • Tsiambas E, Karameris A, Dervenis C, et al. HER2/neu expression and gene alterations in pancreatic ductal adenocarcinoma: a comparative immunohistochemistry and chromogenic in situ hybridization study based on tissue microarrays and computerized image analysis. JOP 2006; 7:283-294. The authors highlight the importance of correlating gene and protein expression. Also they discuss the benefits of computer assisted analysis of immunohistochemistry.
  • 33
    • 33645731188 scopus 로고    scopus 로고
    • Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine
    • This study investigated gemcitabine resistance by analysis of resistance gene expression using PCR, which might be an important step towards personalized medicine
    • Giovannetti E, Del TM, Mey V, et al. Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine. Cancer Res 2006; 66:3928-3935. This study investigated gemcitabine resistance by analysis of resistance gene expression using PCR, which might be an important step towards personalized medicine.
    • (2006) Cancer Res , vol.66 , pp. 3928-3935
    • Giovannetti, E.1    Del, T.M.2    Mey, V.3
  • 34
    • 0141960797 scopus 로고    scopus 로고
    • Yield of endoscopic ultrasoundguided fine-needle aspiration biopsy in patients with suspected pancreatic carcinoma
    • Eloubeidi MA, Jhala D, Chhieng DC, et al. Yield of endoscopic ultrasoundguided fine-needle aspiration biopsy in patients with suspected pancreatic carcinoma. Cancer 2003; 99:285-292.
    • (2003) Cancer , vol.99 , pp. 285-292
    • Eloubeidi, M.A.1    Jhala, D.2    Chhieng, D.C.3
  • 35
    • 33645241968 scopus 로고    scopus 로고
    • Determination of qualitative telomerase activity as an adjunct to the diagnosis of pancreatic adenocarcinoma by EUS-guided fine-needle aspiration
    • The combination of cytology with cancer specific markers can increase sensitivity and specificity for diagnosis
    • Mishra G, Zhao Y, Sweeney J, et al. Determination of qualitative telomerase activity as an adjunct to the diagnosis of pancreatic adenocarcinoma by EUS-guided fine-needle aspiration. Gastrointest Endosc 2006; 63:648-654. The combination of cytology with cancer specific markers can increase sensitivity and specificity for diagnosis.
    • (2006) Gastrointest Endosc , vol.63 , pp. 648-654
    • Mishra, G.1    Zhao, Y.2    Sweeney, J.3
  • 37
    • 33846813656 scopus 로고    scopus 로고
    • Expression profiling identifies microRNA signature in pancreatic cancer
    • This is an adjacent publication in the same field as the previous article
    • Lee EJ, Gusev Y, Jiang J, et al. Expression profiling identifies microRNA signature in pancreatic cancer. Int J Cancer 2007; 120:1046-1054. This is an adjacent publication in the same field as the previous article.
    • (2007) Int J Cancer , vol.120 , pp. 1046-1054
    • Lee, E.J.1    Gusev, Y.2    Jiang, J.3
  • 38
    • 4544301890 scopus 로고    scopus 로고
    • Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: A review of 418 cases and a classification proposal
    • Kosmahl M, Pauser U, Peters K, et al. Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: a review of 418 cases and a classification proposal. Virchows Arch 2004; 445:168-178.
    • (2004) Virchows Arch , vol.445 , pp. 168-178
    • Kosmahl, M.1    Pauser, U.2    Peters, K.3
  • 39
    • 33644858894 scopus 로고    scopus 로고
    • Cyst fluid analysis to diagnose pancreatic cystic lesions: An as yet unfulfilled promise
    • This selected summary provides a good discussion about recent articles in the field
    • Pelaez-Luna M, Chari ST. Cyst fluid analysis to diagnose pancreatic cystic lesions: an as yet unfulfilled promise. Gastroenterology 2006; 130:1007-1009. This selected summary provides a good discussion about recent articles in the field.
    • (2006) Gastroenterology , vol.130 , pp. 1007-1009
    • Pelaez-Luna, M.1    Chari, S.T.2
  • 40
    • 23944431914 scopus 로고    scopus 로고
    • Cyst fluid analysis in the differential diagnosis of pancreatic cystic lesions: A pooled analysis
    • van der Waaij LA, van Dullemen HM, Porte RJ. Cyst fluid analysis in the differential diagnosis of pancreatic cystic lesions: a pooled analysis. Gastrointest Endosc 2005; 62:383-389.
    • (2005) Gastrointest Endosc , vol.62 , pp. 383-389
    • van der Waaij, L.A.1    van Dullemen, H.M.2    Porte, R.J.3
  • 41
    • 33645999371 scopus 로고    scopus 로고
    • Kobayashi M, Ueyama Y, Nakanishi H, et al. Immunocytochemical detection using CDX2: An aid for discerning tumor involvement in ascites cytology. Cancer 2006; 108:114-118. This article focuses on a little observed source for biomarker studies.
    • Kobayashi M, Ueyama Y, Nakanishi H, et al. Immunocytochemical detection using CDX2: An aid for discerning tumor involvement in ascites cytology. Cancer 2006; 108:114-118. This article focuses on a little observed source for biomarker studies.
  • 42
    • 33846199620 scopus 로고    scopus 로고
    • The role of endoscopic ultrasound and endoscopic ultrasound-guided fine-needle aspiration in distinguishing pancreatic cystic lesions
    • Moparty B, Logrono R, Nealon WH, et al. The role of endoscopic ultrasound and endoscopic ultrasound-guided fine-needle aspiration in distinguishing pancreatic cystic lesions. Diagn Cytopathol 2007; 35:18-25.
    • (2007) Diagn Cytopathol , vol.35 , pp. 18-25
    • Moparty, B.1    Logrono, R.2    Nealon, W.H.3
  • 43
    • 33646551746 scopus 로고    scopus 로고
    • Development of a 111In-labeled peptide derivative targeting a chemokine receptor, CXCR4, for imaging tumors
    • This study provides profound data for the use of molecular markers for imaging applications
    • Hanaoka H, Mukai T, Tamamura H, et al. Development of a 111In-labeled peptide derivative targeting a chemokine receptor, CXCR4, for imaging tumors. Nucl Med Biol 2006; 33:489-494. This study provides profound data for the use of molecular markers for imaging applications.
    • (2006) Nucl Med Biol , vol.33 , pp. 489-494
    • Hanaoka, H.1    Mukai, T.2    Tamamura, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.