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Volumn 157, Issue 1, 2015, Pages 65-77

Modulation of STAT3 and STAT5 activity rectifies the imbalance of Th17 and Treg cells in patients with acute coronary syndrome

Author keywords

Acute coronary syndrome; STAT3; STAT5; Th17 cells; Treg cells

Indexed keywords

FEDRATINIB; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; JANUS KINASE 2; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR FOXP3; CYTOKINE;

EID: 84921461763     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2014.12.012     Document Type: Article
Times cited : (43)

References (43)
  • 1
    • 0030996001 scopus 로고    scopus 로고
    • Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
    • Murray C.J., Lopez A.D. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet 1997, 349:1436-1442.
    • (1997) Lancet , vol.349 , pp. 1436-1442
    • Murray, C.J.1    Lopez, A.D.2
  • 2
    • 71549121695 scopus 로고    scopus 로고
    • Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies
    • Klingenberg R., Hansson G.K. Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies. Eur. Heart J. 2009, 30:2838-2844.
    • (2009) Eur. Heart J. , vol.30 , pp. 2838-2844
    • Klingenberg, R.1    Hansson, G.K.2
  • 7
    • 35548944961 scopus 로고    scopus 로고
    • SnapShot: JAK-STAT signaling
    • Mertens C., Darnell J.E. SnapShot: JAK-STAT signaling. Cell 2007, 131:612.
    • (2007) Cell , vol.131 , pp. 612
    • Mertens, C.1    Darnell, J.E.2
  • 8
    • 0242468041 scopus 로고    scopus 로고
    • Regulation of JAK-STAT signalling in the immune system
    • Shuai K., Liu B. Regulation of JAK-STAT signalling in the immune system. Nat. Rev. Immunol. 2003, 3:900-911.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 900-911
    • Shuai, K.1    Liu, B.2
  • 11
    • 84877134225 scopus 로고    scopus 로고
    • SIRT1 activation protects against autoimmune T cell-driven retinal disease in mice via inhibition of IL-2/Stat5 signaling
    • Gardner P.J., Joshi L., Lee R.W., Dick A.D., Adamson P., Calder V.L. SIRT1 activation protects against autoimmune T cell-driven retinal disease in mice via inhibition of IL-2/Stat5 signaling. J. Autoimmun. 2013, 42:117-129.
    • (2013) J. Autoimmun. , vol.42 , pp. 117-129
    • Gardner, P.J.1    Joshi, L.2    Lee, R.W.3    Dick, A.D.4    Adamson, P.5    Calder, V.L.6
  • 12
    • 33845702595 scopus 로고    scopus 로고
    • Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: implications for the NOD STAT5B mutation in diabetes pathogenesis
    • Murawski M.R., Litherland S.A., Clare-Salzler M.J., Davoodi-Semiromi A. Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: implications for the NOD STAT5B mutation in diabetes pathogenesis. Ann. N. Y. Acad. Sci. 2006, 1079:198-204.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1079 , pp. 198-204
    • Murawski, M.R.1    Litherland, S.A.2    Clare-Salzler, M.J.3    Davoodi-Semiromi, A.4
  • 13
    • 77955890092 scopus 로고    scopus 로고
    • Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses
    • Vogtenhuber C., Bucher C., Highfill S.L., Koch L.K., Goren E., Panoskaltsis-Mortari A., Taylor P.A., Farrar M.A., Blazar B.R. Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses. Blood 2010, 116:466-474.
    • (2010) Blood , vol.116 , pp. 466-474
    • Vogtenhuber, C.1    Bucher, C.2    Highfill, S.L.3    Koch, L.K.4    Goren, E.5    Panoskaltsis-Mortari, A.6    Taylor, P.A.7    Farrar, M.A.8    Blazar, B.R.9
  • 17
    • 85064289101 scopus 로고    scopus 로고
    • Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application
    • Furqan M., Mukhi N., Lee B., Liu D. Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application. Biomark. Res. 2013, 1:5.
    • (2013) Biomark. Res. , vol.1 , pp. 5
    • Furqan, M.1    Mukhi, N.2    Lee, B.3    Liu, D.4
  • 19
    • 77957025756 scopus 로고    scopus 로고
    • Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I
    • Xu L., Kitani A., Stuelten C., McGrady G., Fuss I., Strober W. Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I. Immunity 2010, 33:313-325.
    • (2010) Immunity , vol.33 , pp. 313-325
    • Xu, L.1    Kitani, A.2    Stuelten, C.3    McGrady, G.4    Fuss, I.5    Strober, W.6
  • 21
    • 84874472167 scopus 로고    scopus 로고
    • Interleukin-17 in atherosclerosis and cardio vascular disease the good, the bad, and the unknown
    • Liuzzo G., Trotta F., Pedicino D. Interleukin-17 in atherosclerosis and cardio vascular disease the good, the bad, and the unknown. Eur. Heart J. 2013, 34:556-559.
    • (2013) Eur. Heart J. , vol.34 , pp. 556-559
    • Liuzzo, G.1    Trotta, F.2    Pedicino, D.3
  • 22
    • 33750314730 scopus 로고    scopus 로고
    • Altered status of CD4(+)CD25(+) regulatory T cells in patients with acute coronary syndromes
    • Mor A., Luboshits G., Planer D., Keren G., George J. Altered status of CD4(+)CD25(+) regulatory T cells in patients with acute coronary syndromes. Eur. Heart J. 2006, 27:2530-2537.
    • (2006) Eur. Heart J. , vol.27 , pp. 2530-2537
    • Mor, A.1    Luboshits, G.2    Planer, D.3    Keren, G.4    George, J.5
  • 24
    • 84860630975 scopus 로고    scopus 로고
    • Targeting the interleukin-6/Jak/stat pathway in human malignancies
    • Sansone P., Bromberg J. Targeting the interleukin-6/Jak/stat pathway in human malignancies. J. Clin. Oncol. 2012, 30:1005-1014.
    • (2012) J. Clin. Oncol. , vol.30 , pp. 1005-1014
    • Sansone, P.1    Bromberg, J.2
  • 25
    • 55149087226 scopus 로고    scopus 로고
    • From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited
    • Boniface Katia, Blom Bianca, Liu Yong-Jun, de Waal Malefyt René From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited. Immunol. Rev. 2008, 226:132-146.
    • (2008) Immunol. Rev. , vol.226 , pp. 132-146
    • Boniface, K.1    Blom, B.2    Liu, Y.-J.3    de Waal Malefyt, René4
  • 26
    • 81055126760 scopus 로고    scopus 로고
    • Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell-stimulated T cells yet preserves immunity to recall antigen
    • Betts B.C., Abdel-Wahab O., Curran S.A., St Angelo E.T., Koppikar P., Heller G., Levine R.L., Young J.W. Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell-stimulated T cells yet preserves immunity to recall antigen. Blood 2011, 118:5330-5339.
    • (2011) Blood , vol.118 , pp. 5330-5339
    • Betts, B.C.1    Abdel-Wahab, O.2    Curran, S.A.3    St Angelo, E.T.4    Koppikar, P.5    Heller, G.6    Levine, R.L.7    Young, J.W.8
  • 27
    • 77749245810 scopus 로고    scopus 로고
    • C-Rel: a pioneer in directing regulatory T-cell lineage commitment
    • Hori S. c-Rel: a pioneer in directing regulatory T-cell lineage commitment. Eur. J. Immunol. 2010, 40:664-667.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 664-667
    • Hori, S.1
  • 30
    • 76749133610 scopus 로고    scopus 로고
    • Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
    • Zheng Y., Josefowicz S., Chaudhry A., Peng X.P., Forbush K., Rudensky A.Y. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 2010, 463:808-812.
    • (2010) Nature , vol.463 , pp. 808-812
    • Zheng, Y.1    Josefowicz, S.2    Chaudhry, A.3    Peng, X.P.4    Forbush, K.5    Rudensky, A.Y.6
  • 31
    • 84865367294 scopus 로고    scopus 로고
    • STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease
    • Laurence A., Amarnath S., Mariotti J., Kim Y.C., Foley J., Eckhaus M., O'Shea J.J., Fowler D.H. STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease. Immunity 2012, 37:209-222.
    • (2012) Immunity , vol.37 , pp. 209-222
    • Laurence, A.1    Amarnath, S.2    Mariotti, J.3    Kim, Y.C.4    Foley, J.5    Eckhaus, M.6    O'Shea, J.J.7    Fowler, D.H.8
  • 33
    • 55149094300 scopus 로고    scopus 로고
    • Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
    • Koenen H.J., Smeets R.L., Vink P.M., van Rijssen E., Boots A.M., Joosten I. Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 2008, 112:2340-2352.
    • (2008) Blood , vol.112 , pp. 2340-2352
    • Koenen, H.J.1    Smeets, R.L.2    Vink, P.M.3    van Rijssen, E.4    Boots, A.M.5    Joosten, I.6
  • 34
    • 84867211431 scopus 로고    scopus 로고
    • Osteopontin promotes inflammation in patients with acute coronary syndrome through its activity on IL-17 producing cells
    • Zheng Y., Wang Z., Deng L., Yuan X.L., Ma Y., Zhang G., Gantier M.P., Liu J.P., Shen L., Xu D. Osteopontin promotes inflammation in patients with acute coronary syndrome through its activity on IL-17 producing cells. Eur. J. Immunol. 2012, 42:2803-2814.
    • (2012) Eur. J. Immunol. , vol.42 , pp. 2803-2814
    • Zheng, Y.1    Wang, Z.2    Deng, L.3    Yuan, X.L.4    Ma, Y.5    Zhang, G.6    Gantier, M.P.7    Liu, J.P.8    Shen, L.9    Xu, D.10
  • 36
    • 78049318852 scopus 로고    scopus 로고
    • Developmental plasticity of Foxp3+ regulatory T cells
    • Hori S. Developmental plasticity of Foxp3+ regulatory T cells. Curr. Opin. Immunol. 2010, 22:575-582.
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 575-582
    • Hori, S.1
  • 37
    • 34249799285 scopus 로고    scopus 로고
    • Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta
    • Xu L., Kitani A., Fuss I., Strober W. Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. J. Immunol. 2007, 178:6725-6729.
    • (2007) J. Immunol. , vol.178 , pp. 6725-6729
    • Xu, L.1    Kitani, A.2    Fuss, I.3    Strober, W.4
  • 39
    • 80054834740 scopus 로고    scopus 로고
    • IL-17 induces apoptosis of vascular endothelial cells: a potential mechanism for human acute coronary syndrome
    • Zhu F., Wang Q., Guo C., Wang X., Cao X., Shi Y., Gao F., Ma C., Zhang L. IL-17 induces apoptosis of vascular endothelial cells: a potential mechanism for human acute coronary syndrome. Clin. Immunol. 2011, 141:152-160.
    • (2011) Clin. Immunol. , vol.141 , pp. 152-160
    • Zhu, F.1    Wang, Q.2    Guo, C.3    Wang, X.4    Cao, X.5    Shi, Y.6    Gao, F.7    Ma, C.8    Zhang, L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.