Dectin-2 deficiency promotes Th2 response and mucin production in the lungs after pulmonary infection with Cryptococcus neoformans

Infection and Immunity

Volumn 83, Issue 2, 2015, Pages 671-681

  Nakamura, Yuri ^a,c   Sato, Ko ^a   Yamamoto, Hideki ^a   Matsumura, Kana ^a   Matsumoto, Ikumi ^a   Nomura, Toshiki ^a   Miyasaka, Tomomitsu ^a,e   Ishii, Keiko ^a   Kanno, Emi ^a   Tachi, Masahiro ^a   Yamasaki, Sho ^b   Saijo, Shinobu ^c   Iwakura, Yoichiro ^d   Kawakami, Kazuyoshi ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d TOKYO UNIVERSITY OF SCIENCE   (Japan)

^e TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN 1; CATHELICIDIN; CD86 ANTIGEN; DECTIN 2; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 4 ANTIBODY; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; MUCIN; SURFACTANT PROTEIN A; SURFACTANT PROTEIN D; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR ALPHA; ANTIMICROBIAL CATIONIC PEPTIDE; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; CD86 PROTEIN, MOUSE; DECTIN-2, MOUSE; DEFENSIN; HLA ANTIGEN CLASS 2; INTERLEUKIN 12P40; INTERLEUKIN 4; LECTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW DERIVED DENDRITIC CELL; CELL ASSAY; CELL DISRUPTION; CELL LYSATE; CONTROLLED STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; CYTOKINE PRODUCTION; FEMALE; GENE DISRUPTION; HISTOPATHOLOGY; HOST RESISTANCE; IMMUNE RESPONSE; INFLAMMATION; LEUKOCYTE; LUNG ALVEOLUS MACROPHAGE; LUNG INFECTION; MALE; MOUSE; NONHUMAN; PATHOGEN CLEARANCE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; TH2 CELL; WILD TYPE; YEAST CELL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; DENDRITIC CELL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG; LUNG MYCOSIS; MICROBIOLOGY; PATHOLOGY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD86; ANTIMICROBIAL CATIONIC PEPTIDES; CELLS, CULTURED; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DEFENSINS; DENDRITIC CELLS; FEMALE; GREEN FLUORESCENT PROTEINS; HISTOCOMPATIBILITY ANTIGENS CLASS II; INFLAMMATION; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-4; LECTINS, C-TYPE; LUNG; LUNG DISEASES, FUNGAL; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUCINS; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; PULMONARY SURFACTANT-ASSOCIATED PROTEIN D; TH1 CELLS; TH17 CELLS; TH2 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84921417482     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.02835-14     Document Type: Article

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