Antimicrobial, antioxidant, and cytotoxic properties of Vasicine acetate synthesized from Vasicine isolated from adhatoda vasica l.

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Duraipandiyan, V ^a,b   Al Dhabi, N A ^a   Balachandran, C ^b   Ignacimuthu, S ^a,b   Sankar, C ^b   Balakrishna, K ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b LOYOLA COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

UNCLASSIFIED DRUG; VASICINE; VASICINE ACETATE; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; ALKALOID; ANTIINFECTIVE AGENT; ANTIOXIDANT; BIPHENYL DERIVATIVE; PICRIC ACID; PLANT EXTRACT; QUINAZOLINE DERIVATIVE;

A549 CELL LINE; ACETYLATION; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DPPH RADICAL SCAVENGING ASSAY; DRUG DEVELOPMENT; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; DRY WEIGHT; ENTEROBACTER AEROGENES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; JUSTICIA ADHATODA; LUNG ADENOCARCINOMA; MICROCOCCUS LUTEUS; MINIMUM INHIBITORY CONCENTRATION; PLANT LEAF; PSEUDOMONAS AERUGINOSA; QUANTITATIVE ANALYSIS; STAPHYLOCOCCUS EPIDERMIDIS; BACTERIUM; CELL DEATH; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; JUSTICIA (PLANT); MICROBIAL SENSITIVITY TEST; TUMOR CELL LINE; ULTRAVIOLET SPECTROPHOTOMETRY;

ACANTHACEAE; JUSTICIA ADHATODA; STAPHYLOCOCCUS EPIDERMIDIS;

ALKALOIDS; ANTI-BACTERIAL AGENTS; ANTIOXIDANTS; BACTERIA; BIPHENYL COMPOUNDS; CELL DEATH; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; JUSTICIA; MICROBIAL SENSITIVITY TESTS; PICRATES; PLANT EXTRACTS; QUINAZOLINES; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84921417208     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/727304     Document Type: Article

References (25)

1. A. L. Demain and S. Sanchez, and quot;Microbial drug discovery: 80 Years of progress, and " Journal of Antibiotics, vol. 62, no. 1, pp. 5-16, 2009.
2. R. Wise, and quot;The worldwide threat of antimicrobial resistance, and " Current Science, vol. 95, no. 2, pp. 181-187, 2008.
3. J. Ferlay, H.-R. Shin, F. Bray, D. Forman, C. Mathers, and D. M. Parkin, and quot;Estimates of worldwide burden of cancer in 2008: GLOBOCAN, and " International Journal of Cancer, vol. 127, no. 12, pp. 2893-2917, 2010.
4. R. N. Chopra, S. L. Nayar, and I. C. Chopra, Glossary of Indian Medicinal Plants, Council of Scientific and Industrial Research, New Delhi, India, 1956.
5. L. D. Kapoor, Handbook of AyurvedicMedicinal Plants, pp. 416-417, CRC Press, Boca Raton, Fla, USA, 2001.
6. P. V. Sharma, Classical Uses of Medicinal Plants, Chaukhambha Visvabharti, Varanasi, India, 1st edition, 1996.
7. R. L. Wakhloo, D. Wakhloo, O. P. Gupta, and C. K. Atal, and quot;Vasicine hydrochloride, a new drug for interruption of pregnancy, and " Journal of Obstetrics and Gynaecology of India, vol. 29, pp. 939-940, 1979.
8. J. J. Doshi, V. K. Patel, and H. Venkatakrishna-Batt, and quot;Effect of Adhatoda vasica massage in pyorrhoea, and " International Journal of Crude Drug Research, vol. 21, no. 4, pp. 173-176, 1983.
9. A. S. Mathew, K. N. Patel, and B. K. Shah, and quot;Investigation on antifeedant and anthelmentic potential of Adhatoda vasica nees, and " Indian Journal of Natural Products and Resources, vol. 14, pp. 11-16, 1998.
10. J. N. Dhuley, and quot;Antitussive effect of Adhatoda vasica extract on mechanical or chemical stimulation-induced coughing in animals, and " Journal of Ethnopharmacology, vol. 67, no. 3, pp. 361-365, 1999.
11. M. M. Sadek, and quot;Antifeedant and toxic activity of Adhatoda vasica leaf extract against Spodoptera littoralis (Lep., Noctuidae), and " Journal of Applied Entomology, vol. 127, no. 7, pp. 396-404, 2003.
12. U. P. Claeson, T. Malmfors, G. Wikman, and J. G. Bruhn, and quot;Adhatoda vasica: a critical reviewof ethnopharmacological and toxicological data, and " Journal of Ethnopharmacology, vol. 72, no. 1-2, pp. 1-20, 2000
13. Wealth of India A Dictionary of Indian Raw Materials: Volume II: B (revised), Publications and Information Directorate, New Delhi, India, 1998.
14. O. P. Gupta, M. L. Sharma, B. J. R. Ghatak, and C. K. Atal, and quot;Potent uterine activity of alkaloid vasicine, and " Indian Journal of Medical Research, vol. 66, no. 5, pp. 865-871, 1977.
15. S. Ignacimuthu and N. Shanmugam, and quot;Antimycobacterial activity of two natural alkaloids, vasicine acetate and 2-acetyl benzylamine, isolated fromIndian shrub Adhatoda vasica Ness. leaves, and " Journal of Biosciences, vol. 35, no. 4, pp. 565-570, 2010.
16. C. Balachandran, V. Duraipandiyan, N. A. Al-Dhabi et al., and quot;Antimicrobial and antimycobacterial activities of methyl caffeate isolated from Solanum torvum Swartz. Fruit, and " Indian Journal of Microbiology, vol. 52, no. 4, pp. 676-681, 2012.
17. C. Balachandran, Y. Arun, V. Duraipandiyan, S. Ignacimuthu, K. Balakrishna, and N. A. Al-Dhabi, and quot;Antimicrobial and cytotoxicity properties of 2, 3-dihydroxy-9, 10-anthraquinone isolated from Streptomyces galbus (ERINLG-127), and " Applied Biochemistry and Biotechnology, vol. 172, no. 7, pp. 3513-3528, 2014.
18. Clinical and Laboratory Standards Institute (CLSI), Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi; Approved Standard, CLSI Document M38-A2, Clinical and Laboratory Standards Institute, Wayne, Pa, USA, 2nd edition, 2008.
19. X. Wang, X. Li, and D. Chen, and quot;Evaluation of antioxidant activity of isoferulic acid in vitro, and quot;Natural Product Communications, vol. 6, no. 9, pp. 1285-1288, 2011.
20. C. Balachandran, V. Duraipandiyan, and S. Ignacimuthu, and quot;Cytotoxic (A549) and antimicrobial effects of Methylobacterium sp. isolate (ERI-135) from Nilgiris forest soil, India, and " Asian Pacific Journal of Tropical Biomedicine, vol. 2, no. 9, pp. 712-716, 2012.
21. B. S. Joshi, Y. Bai, M. S. Puar, K. K. Dubose, and S. W. Pelletier, and " 1H-and 13C-NMR assignments for some pyrrolo(2, 1b)-quinazoline alkaloids of Adhatoda vasica, and " Journal of Natural Products, vol. 57, no. 7, pp. 953-962, 1994.
22. M. A. El-Shanawany, H. M. Sayed, S. R. M. Ibrahim, and M. A. A. Fayed, and quot;5-hydroxy vasentine, a new pyrroloquinazoline alkaloids from Anisotes trisulcus (Forssk. ) Nees, and " Journal of Natural Product and Plant Resources, vol. 1, pp. 80-85, 2011.
23. A. Karthikeyan, V. Shanthi, and A. Nagasathaya, and quot;Preliminary phytochemical and antibacterial screening of crude extract of the leaf of Adhatoda vasica. L, and " International Journal of Green Pharmacy, vol. 3, no. 1, pp. 78-80, 2009.
24. A. A. Kulkarni, and quot;Ray of hope for cancer patients, and " in Proceedings of the International Seminar on Holistic Management of Cancer, Ayurvedic Education: Series No. 67, pp. 5-11, 1998.
25. G. Roja, B. H. Vikrant, S. K. Sandur, A. Sharma, and K. K. Pushpa, and quot;Accumulation of vasicine and vasicinone in tissue cultures of Adhatoda vasica and evaluation of the free radicalscavenging activities of the various crude extracts, and " Food Chemistry, vol. 126, no. 3, pp. 1033-1038, 2011.