메뉴 건너뛰기




Volumn 11, Issue 4, 2015, Pages 2947-2952

MicroRNA-100 functions as a tumor suppressor by inhibiting Lgr5 expression in colon cancer cells

Author keywords

Colon cancer; G protein coupled receptor 5; MicroRNA; MicroRNA 100; catenin

Indexed keywords

BETA CATENIN; G PROTEIN COUPLED RECEPTOR; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 5; MICRORNA 100; UNCLASSIFIED DRUG; WNT PROTEIN; 3' UNTRANSLATED REGION; LGR5 PROTEIN, HUMAN; MICRORNA; MIRN100 MICRORNA, HUMAN;

EID: 84921367730     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.3052     Document Type: Article
Times cited : (28)

References (24)
  • 1
    • 84886706680 scopus 로고    scopus 로고
    • Impact of physical activity on cancer-specific and overall survival of patients with colorectal cancer
    • Des Guetz G, Uzzan B, Bouillet T., et al.: Impact of physical activity on cancer-specific and overall survival of patients with colorectal cancer. Gastroenterol Res Pract 2013: 340851, 2013.
    • (2013) Gastroenterol Res Pract , vol.2013
    • Des Guetz, G.1    Uzzan, B.2    Bouillet, T.3
  • 5
    • 84880921276 scopus 로고    scopus 로고
    • Adult-specific functions of animal microRNAs
    • Sun K and Lai EC: Adult-specific functions of animal microRNAs. Nat Rev Genet 14: 535-548, 2013.
    • (2013) Nat Rev Genet , vol.14 , pp. 535-548
    • Sun, K.1    Lai, E.C.2
  • 6
    • 84880770383 scopus 로고    scopus 로고
    • Diversifying microRNA sequence and function
    • Ameres SL and Zamore PD: Diversifying microRNA sequence and function. Nat Rev Mol Cell Biol 14: 475-488, 2013.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 475-488
    • Ameres, S.L.1    Zamore, P.D.2
  • 9
    • 84876696774 scopus 로고    scopus 로고
    • Microrna-32 (miR-32) regulates phosphatase and tensin homologue (PTEN) expression and promotes growth, migration, and invasion in colorectal carcinoma cells
    • Wu W, Yang J, Feng X., Wang H, Ye S, Yang P., Tan W, Wei G and Zhou Y: MicroRNA-32 (miR-32) regulates phosphatase and tensin homologue (PTEN) expression and promotes growth, migration, and invasion in colorectal carcinoma cells. Mol Cancer 12: 30, 2013.
    • (2013) Mol Cancer , vol.12 , pp. 30
    • Wu, W.1    Yang, J.2    Feng, X.3    Wang, H.4    Ye, S.5    Yang, P.6    Tan, W.7    Wei, G.8    Zhou, Y.9
  • 10
    • 84884414160 scopus 로고    scopus 로고
    • Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice
    • Yuan K, Xie K, Fox J., Zeng H, Gao H, Huang C and Wu M: Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice. Gastroenterology 145: 853-864, 2013.
    • (2013) Gastroenterology , vol.145 , pp. 853-864
    • Yuan, K.1    Xie, K.2    Fox, J.3    Zeng, H.4    Gao, H.5    Huang, C.6    Wu, M.7
  • 11
    • 38749089854 scopus 로고    scopus 로고
    • MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
    • Schetter AJ, Leung SY, Sohn J.J., Zanetti KA et al.: MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 299: 425-436, 2008.
    • (2008) JAMA , vol.299 , pp. 425-436
    • Schetter, A.J.1    Leung, S.Y.2    Sohn, J.J.3    Zanetti, K.A.4
  • 12
    • 62549118631 scopus 로고    scopus 로고
    • Wnt signaling, lgr5, and stem cells in the intestine and skin
    • Haegebarth A and Clevers H: Wnt signaling, lgr5, and stem cells in the intestine and skin. Am J Pathol 174: 715-721, 2009.
    • (2009) Am J Pathol , vol.174 , pp. 715-721
    • Haegebarth, A.1    Clevers, H.2
  • 13
    • 84882715086 scopus 로고    scopus 로고
    • Diabetes: Human β-cell proliferation by promoting wnt signalling
    • Wilson C: Diabetes: Human β-cell proliferation by promoting Wnt signalling. Nat Rev Endocrinol 9: 502, 2013.
    • (2013) Nat Rev Endocrinol , vol.9 , pp. 502
    • Wilson, C.1
  • 14
    • 84899044888 scopus 로고    scopus 로고
    • MicroRNA-100 inhibits osteosarcoma cell proliferation by targeting cyr61
    • Huang J, Gao K, Lin J and Wang Q: MicroRNA-100 inhibits osteosarcoma cell proliferation by targeting Cyr61. Tumour Biol 35: 1095-1100, 2014.
    • (2014) Tumour Biol , vol.35 , pp. 1095-1100
    • Huang, J.1    Gao, K.2    Lin, J.3    Wang, Q.4
  • 15
    • 84855349331 scopus 로고    scopus 로고
    • MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid Leukemia
    • Zheng YS, Zhang H, Zhang X.J., Feng DD, et al.: MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia. Oncogene 31: 80-92, 2012.
    • (2012) Oncogene , vol.31 , pp. 80-92
    • Zheng, Y.S.1    Zhang, H.2    Zhang, X.J.3    Feng, D.D.4
  • 16
    • 84885428640 scopus 로고    scopus 로고
    • Downregulation of microRNA-100 correlates with tumor progression and poor prognosis in hepato-cellular carcinoma
    • Chen P, Zhao X and Ma L: Downregulation of microRNA-100 correlates with tumor progression and poor prognosis in hepato-cellular carcinoma. Mol Cell Biochem 383: 49-58, 2013.
    • (2013) Mol Cell Biochem , vol.383 , pp. 49-58
    • Chen, P.1    Zhao, X.2    Ma, L.3
  • 17
    • 84868675551 scopus 로고    scopus 로고
    • Micro RNA-100 is a potential molecular marker of non-small cell lung cancer and functions as a tumor suppressor by targeting polo-like kinase 1
    • Liu J, Lu KH, Liu Z L, Sun M, De W and Wang ZX: Micro RNA-100 is a potential molecular marker of non-small cell lung cancer and functions as a tumor suppressor by targeting polo-like kinase 1. BMC Cancer 12: 519, 2012.
    • (2012) BMC Cancer , vol.12 , pp. 519
    • Liu, J.1    Lu, K.H.2    Liu, Z.L.3    Sun, M.4    De, W.5    Wang, Z.X.6
  • 18
    • 84880305345 scopus 로고    scopus 로고
    • Mir-100 suppresses IGF2 and inhibits Breast tumorigenesis by interfering with proliferation and survival signaling
    • Gebeshuber CA and Martinez J: miR-100 suppresses IGF2 and inhibits breast tumorigenesis by interfering with proliferation and survival signaling. Oncogene 32: 3306-3310, 2013.
    • (2013) Oncogene , vol.32 , pp. 3306-3310
    • Gebeshuber, C.A.1    Martinez, J.2
  • 19
    • 84862666215 scopus 로고    scopus 로고
    • Lgr5 and lgr6 as markers to study adult stem cell roles in self-renewal and cancer
    • Leushacke M and Barker N: Lgr5 and Lgr6 as markers to study adult stem cell roles in self-renewal and cancer. Oncogene 31: 3009-3022, 2012.
    • (2012) Oncogene , vol.31 , pp. 3009-3022
    • Leushacke, M.1    Barker, N.2
  • 20
    • 84872408527 scopus 로고    scopus 로고
    • Leucine-rich repeat-containing G protein-c o uple d receptor 5 regulates epithelial cell phenotype and survival of hepato-cellular carcinoma cells
    • Fukuma M, Tanese K, Effendi K., Yamazaki K, Masugi Y, Suda M and Sakamoto M: Leucine-rich repeat-containing G protein-c o uple d receptor 5 regulates epithelial cell phenotype and survival of hepato-cellular carcinoma cells. Exp Cell Res 319: 113-121, 2013.
    • (2013) Exp Cell Res , vol.319 , pp. 113-121
    • Fukuma, M.1    Tanese, K.2    Effendi, K.3    Yamazaki, K.4    Masugi, Y.5    Suda, M.6    Sakamoto, M.7
  • 22
    • 84862230930 scopus 로고    scopus 로고
    • Adult Mammalian stem cells: The role of wnt, lgr5 and R-spondins
    • Schuijers J and Clevers H: Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins. EMBO J 31: 2685-2696, 2012.
    • (2012) EMBO J , vol.31 , pp. 2685-2696
    • Schuijers, J.1    Clevers, H.2
  • 23
    • 78649896525 scopus 로고    scopus 로고
    • Severe polyposis in apc(1322T) mice is associated with submaximal wnt signalling and increased expression of the stem cell marker lgr5
    • Lewis A, Segditsas S, Deheragoda M., et al.: Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5. Gut 59: 1680-1686, 2010.
    • (2010) Gut , vol.59 , pp. 1680-1686
    • Lewis, A.1    Segditsas, S.2    Deheragoda, M.3
  • 24
    • 84893156862 scopus 로고    scopus 로고
    • Over-expression of LGR5 correlates with poor survival of colon cancer in mice as well as in patients
    • Liu Z, Dai W, Jiang L and Cheng Y: Over-expression of LGR5 correlates with poor survival of colon cancer in mice as well as in patients. Neoplasma 61: 177-185, 2014.
    • (2014) Neoplasma , vol.61 , pp. 177-185
    • Liu, Z.1    Dai, W.2    Jiang, L.3    Cheng, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.