Inhibition of ERK1/2 signaling prevents epileptiform behavior in rats prone to audiogenic seizures

Journal of Neurochemistry

Volumn 132, Issue 2, 2015, Pages 218-229

  Glazova, Margarita V ^a   Nikitina, Liubov S ^a,b   Hudik, Kirill A ^a   Kirillova, Olga D ^a   Dorofeeva, Nadezhda A ^a   Korotkov, Anatoly A ^a   Chernigovskaya, Elena V ^a  

^a SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

^b ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

Author keywords

SL 327; SNAP25; synapsin I; VAMP2; VGLUT2

Indexed keywords

4 AMINOBUTYRIC ACID; ALPHA [AMINO(4 AMINOPHENYLTHIO)METHYLENE] 2 (TRIFLUOROMETHYL)PHENYLACETONITRILE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 42; MITOGEN ACTIVATED PROTEIN KINASE 44; SYNAPSIN I; SYNAPTOBREVIN 2; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER 2; AMINOACETONITRILE; CREBBP PROTEIN, RAT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE PROTEIN; PROTEIN KINASE INHIBITOR; SLC17A6 PROTEIN, RAT; SNAP25 PROTEIN, RAT; SYNAPSIN; VAMP2 PROTEIN, RAT;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDIOGENIC SEIZURE; AUDITORY STIMULATION; CONTROLLED STUDY; DENTATE GYRUS; DISEASE SEVERITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPILEPSY; EXOCYTOSIS; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LATENT PERIOD; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; TEMPORAL CORTEX; TEMPORAL LOBE EPILEPSY; TONIC CLONIC SEIZURE; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BRAIN; DRUG EFFECTS; ENZYMOLOGY; EPILEPSY, REFLEX; FEMALE; GENETICS; MALE; METABOLISM; MUTANT RAT STRAIN; PHYSIOLOGY; PROTEIN PROCESSING; REACTION TIME; SECRETION (PROCESS); SYNAPSE;

ANIMALIA; RATTUS;

ACOUSTIC STIMULATION; AMINOACETONITRILE; ANIMALS; BRAIN; CREB-BINDING PROTEIN; EPILEPSY, REFLEX; EXOCYTOSIS; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NERVE TISSUE PROTEINS; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, MUTANT STRAINS; REACTION TIME; SYNAPSES; SYNAPSINS; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25; VESICLE-ASSOCIATED MEMBRANE PROTEIN 2; VESICULAR GLUTAMATE TRANSPORT PROTEIN 2;

EID: 84921365737     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12982     Document Type: Article

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