Improved cytotoxicity of paclitaxel loaded in nanosized lipid carriers by intracellular delivery

Journal of Nanoparticle Research

Volumn 17, Issue 1, 2015, Pages

  Miao, Jing ^a   Du, Yongzhong ^b   Yuan, Hong ^b   Zhang, Xingguo ^a   Li, Qian ^a   Rao, Yuefeng ^a   Zhao, Mengdan ^c   Hu, Fuqiang ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cellular uptake; Cytotoxicity; Intracellular delivery; Nanomedicine; Nanosized lipid carriers; Paclitaxel

Indexed keywords

CONTROLLED DRUG DELIVERY; CYTOTOXICITY; MEDICAL NANOTECHNOLOGY; TANTALUM COMPOUNDS;

CELLULAR GROWTH; CELLULAR UPTAKE; DRUG CONCENTRATION; INTRACELLULAR DELIVERY; LIPID CARRIERS; PACLITAXEL; SOLID LIPID NANOPARTICLE (SLN); SOLVENT DIFFUSION METHODS;

TARGETED DRUG DELIVERY;

GLYCEROL STEARATE; NANOCARRIER; NANOSIZED LIPID CARRIER; OLEIC ACID; PACLITAXEL; UNCLASSIFIED DRUG;

A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DRUG RELEASE; DRUG TUMOR LEVEL; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; INTRACELLULAR TRANSPORT; NANOPHARMACEUTICS; PARTICLE SIZE; PRIORITY JOURNAL;

EID: 84921325869     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-014-2852-x     Document Type: Article

References (34)

1. Benis S, Chapey C, Couvreur P, Robert J (1994) Enhanced cytotoxicity of doxorubicin encapsulated in polyisohexylcyanoacrylate nanospheres against multi-drug resistant cells in culture. Eur J Cancer 30A:89–93
2. Brigger I, Dubernet C, Couvreur P (2002) Nanoparticles in cancer therapy and diagnosis. Adv Drug Deliv Rev 54:631–651
3. Castelli F, Puglia C, Sarpietro MG, Rizza L, Bonina F (2005) Characterization of indomethacin-loaded lipid nanoparticles by differential scanning calorimetry. Int J Pharm 304:231–238
4. Chávez JL, Wong JL, Duran RS (2008) Core-Shell Nanoparticles: characterization and study of their use for the encapsulation of hydrophobic fluorescent dyes. Langmuir 24:2064–2071
5. Ding JC, Hu FQ, Yuan H (2004) Uptake of monostearin solid lipid nanoparticles by A549 cells. Acta Pharm Sin 39:876–880
6. Drummond DC, Meyer O, Hong K, Kirpotin DB, Papahadjopoulos D (1999) Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacol Rev 51:691–744
7. Garrec DL, Ranger M, Leroux JC (2004) Micelles in anticancer drug delivery. Am J Drug Deliv 2:15–42
8. Gelderblom H, Verweij J, Nooter K, Sparreboom A (2001) Sparreboom. Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur J Cancer 37:1590–1598
9. Gualbert J, Shahgaldian P, Coleman AW (2003) Interactions of amphiphilic calix[4] arene-based solid lipid nanoparticles with bovine serum albumin. Adv Drug Deliv Rev 57:69–73
10. Heo DN, Yang DH, Moon HJ, Lee JB, Bae MS, Lee SC, Lee WJ, Sun IC, Kwon IK (2012) Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy. Biomaterials 33:856–866
11. Hu FQ, Jiang SP, Du YZ, Yuan H, Ye YQ, Zeng S (2005) Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system. Colloids Surf B 45:167–173
12. Hu FQ, Ren GF, Yuan H, Du YZ, Zeng S (2006) Shell cross-linked stearic acid grafted chitosan oligosaccharide self-aggregated micelles for controlled release of paclitaxel. Colloids Surf B 50:97–103
13. Hu Y, Zheng XT, Chen JS, Zhou MJ, Li CM, Lou XW (2011) Silica-based complex nanorattles as multifunctional carrier for anticancer drug. J Mater Chem 21:8052–8056
14. Jenning V, Gohla SH (2001) Encapsulation of retinoids in solid lipid nanoparticles (SLN). J Microencapsul 18:149–158
15. Jenning V, Andreas FT, Gohla SH (2000a) Characterisation of a novel solid lipid nanoparticle carrier system based on binary mixtures of liquid and solid lipids. Int J Pharm 199:167–177
16. Jenning V, Mader K, Gohla SH (2000b) Solid lipid nanoparticles (SLNTM) based on binary mixtures of liquid and solid lipids: a 1HNMR study. Int J Pharm 20:15–21
17. Jores K, Mehnert W, Drechsler M, Bunjes H, Johann C, Mäder K (2004) Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy. J Control Release 95:217–227
18. Maschke A, Becker C, Eyrich D, Kiermaier J, Blunka T, Göpferich A (2007) Development of a spray congealing process for the preparation of insulin-loaded lipid microparticles and characterization. Eur J Pharm Biopharm 65:175–187
19. Miao J, Du YZ, Yuan H, Zhang XG, Hu FQ (2013) Drug resistance reversal activity of anticancer drug loaded solid lipid nanoparticles in multi-drug resistant cancer cells. Colloids Surf B 110:74–80
20. Montasser I, Fessi H, Coleman AW (2002) AFM imaging of novel type of polymeric colloidal nanostructures. Eur J Pharm Biopharm 54:281–284
21. Mu L, Feng SS (2002) Vitamin E TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheresfor controlled release of paclitaxel (Taxol). J Control Release 80:129–144
22. Mühlen AZ, Mühlen EZ, Niehus H, Mehnert W (1996) Atomic force microscopy studies of solid lipid nanoparticles. Pharma Res 13:1411–1416
23. Müller RH, Jacobs C, Kayser O (2001) Nanosuspensions as particulate drug formulations in therapy Rationale for development and what we can expect for the future. Adv Drug Deliv Rev 47:3–19
24. Müller RH, Radtke M, Wissing SA (2002a) Nanostructured lipid matrices for improved microencapsulation of drugs. Int J Pharm 242:121–128
25. Müller RH, Radtke M, Wissing SA (2002b) Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Adv Drug Deliv Rev 54:S131–S155
26. Serpe L, Catalano MG, Cavalli R, Ugazio E, Bosco O, Canaparo R, Muntoni E, Frairia R, Gasco MR, Eandi M, Zara GP (2004) Cytotoxicity of anticancer drugs incorporated in solid lipid nanoparticles on HT-29 colorectal cancer cell line. Eur J Pharm Biopharm 58:673–680
27. Shahgaldian P, Silva ED, Anthony W (2003) Para-acyl-calix-arene based solid lipid nanoparticles (SLNs): a detailed study of preparation and stability parameters. Int J Pharm 253:23–28
28. Souto EB, Wissing SA, Barbosa CM (2004a) Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery. Int J Pharm 278:71–77
29. Souto EB, Wissing SA, Barbosa CM, Müller RH (2004b) Evaluation of the physical stability of SLN and NLC before and after incorporation into hydrogel formulations. Eur J Pharm Biopharm 58:83–90
30. Tranchant T, Besson P, Hoinard C, Delarue J, Antoine JM, Couet C, Goré J (1997) Mechanisms and kinetics of α-linolenic acid uptake in Caco-2 clone TC7. Biochim Biophys Acta 1345:151–161
31. Yang XY, Li YX, Li M, Zhang L, Feng LX, Zhang N (2013) Hyaluronic acid-coated nanostructured lipid carriers for targeting paclitaxel to cancer. Cancer Lett 334:338–345
32. Yuan H, Miao J, Du YZ, You J, Hu FQ, Zeng S (2008) Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells. Int J Pharm 348:137–145
33. Zhan CY, Gu B, Xie C, Li J, Liu Y, Lu WY (2010) Cyclic RGD conjugated poly(ethylene glycol)-co-poly(lactic acid) micelle enhances paclitaxel antiglioblastoma effect. J Control Release 143:136–142
34. Zhang XG, Miao J, Dai YQ, Du YZ, Yuan H, Hu FQ (2008) Reversal activity of nanostructured lipid carriers loading cytotoxic drug in multi-drug resistant cancer cells. Int J Pharm 361:239–244