The diagnostic value of clinical symptoms in women and men presenting with chest pain at the emergency department, a prospective cohort study

PLoS ONE

Volumn 10, Issue 1, 2015, Pages

  Van Der Meer, Manon G ^a   Backus, Barbra E ^a   Van Der Graaf, Yolanda ^a   Cramer, Maarten J ^a   Appelman, Yolande ^a   Doevendans, Pieter A ^a   Six, A Jacob ^b   Nathoe, Hendrik M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b Zuwe Hofpoort Ziekenhuis   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CARDIOVASCULAR RISK; CLINICAL FEATURE; CORONARY ARTERY DISEASE; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DIAPHORESIS; DISEASE ASSOCIATION; DIZZINESS; DYSLIPIDEMIA; EMERGENCY WARD; FAINTNESS; FAMILY HISTORY; FEMALE; HEART PALPITATION; HUMAN; LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; NAUSEA AND VOMITING; PAIN ASSESSMENT; PAIN SEVERITY; PREDICTIVE VALUE; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEX DIFFERENCE; SYMPTOM; THORAX PAIN; AGED; CARDIOVASCULAR DISEASES; CHEST PAIN; COMPLICATION; EMERGENCY HEALTH SERVICE; MIDDLE AGED; RISK FACTOR; SYMPTOM ASSESSMENT;

ADULT; AGED; CARDIOVASCULAR DISEASES; CHEST PAIN; CORONARY ARTERY DISEASE; EMERGENCY SERVICE, HOSPITAL; FEMALE; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SYMPTOM ASSESSMENT;

EID: 84921058830     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116431     Document Type: Article

References (37)

1. Nawar EW, Niska RW, Xu J (2007) National hospital ambulatory medical care survey: 2005 emergency department summary. Adv Data (386:): 1-32. PMID: 17703794
2. Wright RS, Anderson JL, Adams CD, Bridges CR, Casey DE Jr, et al. (2011) 2011 ACCF/AHA focused update incorporated into the ACC/AHA 2007 guidelines for the management of patients with unstable Angina/Non-ST-elevation myocardial infarction: A report of the american college of cardiology Foundation/American heart association task force on practice guidelines developed in collaboration with the american academy of family physicians, society for cardiovascular angiography and interventions, and the society of thoracic surgeons. J Am Coll Cardiol 57: e215-367. PMID: 21545940
3. Hamm CW, Bassand JP, Agewall S, Bax J, Boersma E, et al. (2011) ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The task force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the european society of cardiology (ESC). Eur Heart J 32: 2999-3054. PMID: 21873419
4. Panju AA, Hemmelgarn BR, Guyatt GH, Simel DL (1998) The rational clinical examination. is this patient having a myocardial infarction? JAMA 280: 1256-1263. doi: 10.1001/jama.280.14.1256 PMID: 9786377
5. Swap CJ, Nagurney JT (2005) Value and limitations of chest pain history in the evaluation of patients with suspected acute coronary syndromes. JAMA 294: 2623-2629. doi: 10.1001/jama.294.20.2623 PMID: 16304077
6. Pope JH, Aufderheide TP, Ruthazer R, Woolard RH, Feldman JA, et al. (2000) Missed diagnoses of acute cardiac ischemia in the emergency department. N Engl J Med 342: 1163-1170. doi: 10.1056/NEJM200004203421603 PMID: 10770981
7. Dey S, Flather MD, Devlin G, Brieger D, Gurfinkel EP, et al. (2009) Sex-related differences in the presentation, treatment and outcomes among patients with acute coronary syndromes: The global registry of acute coronary events. Heart 95: 20-26. doi: 10.1136/hrt.2007.138537 PMID: 18463200
8. Culic V, Eterovic D, Miric D, Silic N (2002) Symptom presentation of acute myocardial infarction: Influence of sex, age, and risk factors. Am Heart J 144: 1012-1017. doi: 10.1067/mhj.2002.125625 PMID: 12486425
9. Milner KA, Vaccarino V, Arnold AL, Funk M, Goldberg RJ (2004) Gender and age differences in chief complaints of acute myocardial infarction (worcester heart attack study). Am J Cardiol 93: 606-608. doi: 10.1016/j.amjcard.2003.11.028 PMID: 14996588
10. Patel H, Rosengren A, Ekman I (2004) Symptoms in acute coronary syndromes: Does sex make a difference? Am Heart J 148: 27-33. doi: 10.1016/j.ahj.2004.03.005 PMID: 15215788
11. Khan NA, Daskalopoulou SS, Karp I, Eisenberg MJ, Pelletier R, et al. (2013) Sex differences in acute coronary syndrome symptom presentation in young patients. JAMA Intern Med 173: 1863-71. PMID: 24043208
12. Canto JG, Goldberg RJ, Hand MM, Bonow RO, Sopko G, et al. (2007) Symptom presentation of women with acute coronary syndromes: Myth vs reality. Arch Intern Med 167: 2405-2413. doi: 10.1001/archinte.167.22.2405 PMID: 18071161
13. Backus BE, Six AJ, Kelder JC, Bosschaert MA, Mast EG, et al. (2013) A prospective validation of the HEART score for chest pain patients at the emergency department. Int J Cardiol 168: 2153-8. doi: 10.1016/j.ijcard.2013.01.255 PMID: 23465250
14. O'Gara PT, Kushner FG, Ascheim DD, Casey DE Jr, Chung MK, et al. (2013) 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: A report of the american college of cardiology Foundation/American heart association task force on practice guidelines. Circulation 127: e362-425.
15. Rutherford J, Braunwald E (1992) Chronic ischemic heart disease. In: Anonymous Heart Disease: A Textbook of Cardiovascular Medicines. Philadelphia: W.B. Saunders. pp. 1293-5.
16. Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, et al. (1999) ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: A report of the american college of Cardiology/American heart association task force on practice guidelines (committee on management of patients with chronic stable angina). J Am Coll Cardiol 33: 2092-2197. PMID: 10362225
17. Thygesen K, Alpert JS, White HD, Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction. (2007) Universal definition of myocardial infarction. Eur Heart J 28: 2525-2538. doi: 10.1093/eurheartj/ehm355 PMID: 17951287
18. Steyerberg EW (2008) Clinical prediction models.: Springer-Verlag New York Inc.
19. Canto JG, Rogers WJ, Goldberg RJ, Peterson ED, Wenger NK, et al. (2012) Association of age and sex with myocardial infarction symptom presentation and in-hospital mortality. JAMA 307: 813-822. doi: 10.1001/jama.2012.199 PMID: 22357832
20. Milner KA, Funk M, Richards S, Vaccarino V, Krumholz HM (2001) Symptom predictors of acute coronary syndromes in younger and older patients. Nurs Res 50: 233-241. doi: 10.1097/00006199-200107000-00007 PMID: 11480532
21. Rubini Gimenez M, Reiter M, Twerenbold R, Reichlin T, Wildi K, et al. (2013) Sex-specific chest pain characteristics in the early diagnosis of acute myocardial infarction. JAMA Intern Med 174: 241-9. doi: 10.1001/jamainternmed.2013.12199
22. Milner KA, Funk M, Arnold A, Vaccarino V (2002) Typical symptoms are predictive of acute coronary syndromes in women. Am Heart J 143: 283-288. doi: 10.1067/mhj.2002.119759 PMID: 11835032
23. Devon HA, Rosenfeld A, Steffen AD, Daya M (2014) Sensitivity, specificity, and sex differences in symptoms reported on the 13-item acute coronary syndrome checklist. J Am Heart Assoc 3: e000586. doi: 10.1161/JAHA.113.000586 PMID: 24695650
24. D'Agostino RBS, Grundy S, Sullivan LM, Wilson P, CHD Risk Prediction Group (2001) Validation of the framingham coronary heart disease prediction scores: Results of a multiple ethnic groups investigation. JAMA 286: 180-187. doi: 10.1001/jama.286.2.180 PMID: 11448281
25. Antman EM, Cohen M, Bernink PJ, McCabe CH, Horacek T, et al. (2000) The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making. JAMA 284: 835-842. doi: 10.1001/jama.284.7.835 PMID: 10938172
26. Forest RS, Shofer FS, Sease KL, Hollander JE (2004) Assessment of the standardized reporting guidelines ECG classification system: The presenting ECG predicts 30-day outcomes. Ann Emerg Med 44: 206-212. doi: 10.1016/j.annemergmed.2004.08.013 PMID: 15332059
27. Halpern EJ, Deutsch JP, Hannaway MM, Estepa AT, Kenia AS, et al. (2013) Cardiac risk factors and risk scores vs cardiac computed tomography angiography: A prospective cohort study for triage of ED patients with acute chest pain. Am J Emerg Med 31: 1479-1485. doi: 10.1016/j.ajem.2013.08.001 PMID: 24035047
28. Searle J, Shih J, Muller R, Vollert JO, Muller C, et al. (2013) The role of myeloperoxidase (MPO) for prognostic evaluation in sensitive cardiac troponin I negative chest pain patients in the emergency department. Eur Heart J Acute Cardiovasc Care 2: 203-210. doi: 10.1177/2048872613484688 PMID: 24222831
29. Sanchis J, Bodi V, Llacer A, Nunez J, Consuegra L, et al. (2005) Risk stratification of patients with acute chest pain and normal troponin concentrations. Heart 91: 1013-1018. doi: 10.1136/hrt.2004.041673 PMID: 16020586
30. Shaw LJ, Shaw RE, Merz CN, Brindis RG, Klein LW, et al. (2008) Impact of ethnicity and gender differences on angiographic coronary artery disease prevalence and in-hospital mortality in the american college of cardiology-national cardiovascular data registry. Circulation 117: 1787-1801. doi: 10.1161/CIRCULATIONAHA.107.726562 PMID: 18378615
31. Johnston N, Schenck-Gustafsson K, Lagerqvist B (2011) Are we using cardiovascular medications and coronary angiography appropriately in men and women with chest pain? Eur Heart J 32: 1331-1336. doi: 10.1093/eurheartj/ehr009 PMID: 21317147
32. Milner KA, Funk M, Richards S, Wilmes RM, Vaccarino V, et al. (1999) Gender differences in symptom presentation associated with coronary heart disease. Am J Cardiol 84: 396-399. doi: 10.1016/S0002-9149(99)00322-7 PMID: 10468075
33. Assiri AS (2011) Gender differences in clinical presentation and management of patients with acute coronary syndrome in southwest of saudi arabia. J Saudi Heart Assoc 23: 135-141. doi: 10.1016/j.jsha.2011.01.007 PMID: 24146527
34. Bruins Slot MH, Rutten FH, van der Heijden GJ, Doevendans PA, Mast EG, et al. (2012) Gender differences in pre-hospital time delay and symptom presentation in patients suspected of acute coronary syndrome in primary care. Fam Pract 29: 332-337. doi: 10.1093/fampra/cmr089 PMID: 22006039
35. Bosner S, Haasenritter J, Hani MA, Keller H, Sonnichsen AC, et al. (2009) Gender differences in presentation and diagnosis of chest pain in primary care. BMC Fam Pract 10: 79. doi: 10.1186/1471-2296-10-79 PMID: 20003406
36. Naaktgeboren CA, de Groot JA, van Smeden M, Moons KG, Reitsma JB (2013) Evaluating diagnostic accuracy in the face of multiple reference standards. Ann Intern Med 159: 195-202. doi: 10.7326/0003-4819-159-3-201308060-00009 PMID: 23922065
37. Roger VL, Farkouh ME, Weston SA, Reeder GS, Jacobsen SJ, et al. (2000) Sex differences in evaluation and outcome of unstable angina. JAMA 283: 646-652. doi: 10.1001/jama.283.5.646 PMID: 10665705