Sex differences in acute coronary syndrome symptom presentation in young patients

JAMA Internal Medicine

Volumn 173, Issue 20, 2013, Pages 1863-1871

  Khan, Nadia A ^a   Daskalopoulou, Stella S ^b,f   Karp, Igor ^c   Eisenberg, Mark J ^d   Pelletier, Roxanne ^b,f   Tsadok, Meytal Avgil ^b,f   Dasgupta, Kaberi ^b,f   Norris, Colleen M ^e   Pilote, Louise ^b,f  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITY OF ALBERTA   (Canada)

^f MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

TROPONIN;

ACUTE CORONARY SYNDROME; ADULT; ARTICLE; COHORT ANALYSIS; CORONARY ARTERY DISEASE; CORONARY ARTERY OBSTRUCTION; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GENDER IDENTITY; HEALTH SURVEY; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEX DIFFERENCE; SEX ROLE; SOCIAL PSYCHOLOGY; SOCIOECONOMICS; TACHYCARDIA; THORAX PAIN;

ACUTE CORONARY SYNDROME; AGE FACTORS; CANADA; CHEST PAIN; COMORBIDITY; FEMALE; GENDER IDENTITY; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SEX CHARACTERISTICS; SOCIOECONOMIC FACTORS;

EID: 84888364156     PISSN: 21686106     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamainternmed.2013.10149     Document Type: Article

References (24)

1. Canto JG, Rogers WJ, Goldberg RJ, et al NRMI Investigators. Association of age and sex with myocardial infarction symptom presentation and in-hospital mortality. JAMA. 2012;307(8):813-822.
2. Brieger D, Eagle KA, Goodman SG, et al GRACE Investigators. Acute coronary syndromes without chest pain, an underdiagnosed and undertreated high-risk group: insights from the Global Registry of Acute Coronary Events. Chest. 2004;126(2):461-469.
3. Canto JG, Goldberg RJ, Hand MM, et al. Symptom presentation of women with acute coronary syndromes: myth vs reality. Arch Intern Med. 2007;167(22):2405-2413.
4. Pope JH, Aufderheide TP, Ruthazer R, et al. Missed diagnoses of acute cardiac ischemia in the emergency department. N Engl J Med. 2000;342(16):1163- 1170.
5. Kaul P, Chang WC, Westerhout CM, Graham MM, Armstrong PW. Differences in admission rates and outcomes between men and women presenting to emergency departments with coronary syndromes. CMAJ. 2007;177(10):1193-1199.
6. Vaccarino V, Parsons L, Peterson ED, Rogers WJ, Kiefe CI, Canto J. Sex differences in mortality after acutemyocardial infarction: changes from 1994 to 2006. Arch Intern Med. 2009;169(19):1767-1774.
7. Pilote L, Karp I. GENESIS-PRAXY (GENdEr and Sex determInantS of cardiovascular disease: From bench to beyond-Premature Acute Coronary SYndrome). Am Heart J. 2012;163(5):741-746; e2.
8. GRACE Variable Definitions-Version of March 2006. www.outcomes-umassmed. org/grace/Files/Standard-Definitions.pdf. Accessed November 18, 2012.
9. McSweeney JC, O'Sullivan P, Cody M, Crane PB. Development of the McSweeney Acute and Prodromal Myocardial Infarction Symptom Survey. J Cardiovasc Nurs. 2004;19(1):58-67.
10. Oswald PA. An examination of the current usefulness of the Bem Sex-Role Inventory. Psychol Rep. 2004;94(3 Pt 2):1331-1336.
11. Bem SL. The measurement of psychological androgyny. J Consult Clin Psychol. 1974;42(2):155-162.
12. Doyle F, McGee HM, De La Harpe D, Shelley E, Conroy R. The Hospital Anxiety and Depression Scale depression subscale, but not the Beck Depression Inventory-Fast Scale, identifies patients with acute coronary syndrome at elevated risk of 1-year mortality. J Psychosom Res. 2006;60(5):461-467.
13. Eagle KA, Lim MJ, Dabbous OH, et al GRACE Investigators. A validated prediction model for all forms of acute coronary syndrome: estimating the risk of 6-month postdischarge death in an international registry. JAMA. 2004;291(22):2727-2733.
14. Arslanian-Engoren C, Patel A, Fang J, et al. Symptoms of men and women presenting with acute coronary syndromes. Am J Cardiol. 2006;98(9):1177-1181.
15. DeVon HA, Zerwic JJ. Symptoms of acute coronary syndromes: are there gender differences? a review of the literature. Heart Lung. 2002;31(4):235-245.
16. Chen W, Woods SL, Puntillo KA. Gender differences in symptoms associated with acute myocardial infarction: a review of the research. Heart Lung. 2005;34(4):240-247.
17. de Torbal A, Boersma E, Kors JA, et al. Incidence of recognized and unrecognizedmyocardial infarction in men and women aged 55 and older: the Rotterdam Study. Eur Heart J. 2006;27(6):729-736.
18. El-Menyar A, Zubaid M, Sulaiman K, et al Gulf Registry of Acute Coronary Events (Gulf RACE) Investigators. Atypical presentation of acute coronary syndrome: a significant independent predictor of in-hospital mortality. J Cardiol. 2011;57(2):165-171.
19. Egiziano G, Akhtari S, Pilote L, Daskalopoulou SS; GENESIS (GENdEr and Sex DetermInants of Cardiovascular Disease) Investigators. Sex differences in young patients with acutemyocardial infarction. Diabet Med. 2013;30(3):e108- e114.
20. Langer A, Freeman MR, Josse RG, Armstrong PW. Metaiodobenzylguanidine imaging in diabetes mellitus: assessment of cardiac sympathetic denervation and its relation to autonomic dysfunction and silent myocardial ischemia. J Am Coll Cardiol. 1995;25(3):610-618.
21. Myers CD, Robinson ME, Riley JL III, Sheffield D. Sex, gender, and blood pressure: contributions to experimental pain report. Psychosom Med. 2001;63(4):545-550.
22. DeVon HA, Ryan CJ, Ochs AL, Shapiro M. Symptoms across the continuum of acute coronary syndromes: differences between women and men. Am J Crit Care. 2008;17(1):14-24.
23. Steptoe A, Brydon L. Emotional triggering of cardiac events. Neurosci Biobehav Rev. 2009;33(2):63-70.
24. Méthot J, Hamelin BA, Bogaty P, Arsenault M, Plante S, Poirier P. Does hormonal status influence the clinical presentation of acute coronary syndromes in women? J Womens Health (Larchmt). 2004;13(6):695-702.