An evaluation of the correlation between hepcidin serum levels and disease activity in inflammatory bowel disease

Gastroenterology Research and Practice

Volumn 2015, Issue , 2015, Pages

  Paköz, Zehra Betül ^a   Çekiç, Cem ^a   Arabul, Mahmut ^a   Sartaş Yüksel, Elif ^a   Ipek, Serkan ^a   Vatansever, Sezgin ^a   Ünsal, Belks ^a  

^a IZMIR KATIP CELEBI UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; FERRITIN; HEMOGLOBIN; HEPCIDIN; INTERLEUKIN 6;

ADULT; ARTICLE; BLOOD SAMPLING; CLINICAL EVALUATION; CORRELATIONAL STUDY; CROHN DISEASE; DEMOGRAPHY; DISEASE ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FERRITIN BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; REMISSION; ULCERATIVE COLITIS;

EID: 84921038815     PISSN: 16876121     EISSN: 1687630X     Source Type: Journal    
DOI: 10.1155/2015/810942     Document Type: Article

References (16)

1. J. Stein, F. Hartmann, and A. U. Dignass, "Diagnosis and management of iron deficiency anemia in patients with IBD," Nature Reviews Gastroenterology and Hepatology, vol. 7, no. 11, pp. 599- 610, 2010.
2. N. Zhao, A.-S. Zhang, and C. A. Enns, "Iron regulation by hepcidin," The Journal of Clinical Investigation, vol. 123, no. 6, pp. 2337-2343, 2013.
3. J.-C. Deschemin and S. Vaulont, "Role of hepcidin in the setting of hypoferremia during acute inflammation," PLoS ONE, vol. 8, no. 4, Article ID e61050, 2013.
4. J. L. Babitt, F. W. Huang, D. M. Wrighting et al. , "Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression," Nature Genetics, vol. 38, no. 5, pp. 531-539, 2006.
5. D. M. Wrighting and N. C. and rews, "Interleukin-6 induces hepcidin expression through STAT3," Blood, vol. 108, no. 9, pp. 3204-3209, 2006.
6. M. S. Silverberg, J. Satsangi, T. Ahmad et al. , "Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005MontrealWorldCongress ofGastroenterology,"TheCanadian Journal of Gastroenterology, vol. 19, supplement A, pp. 5A- 36A, 2005.
7. K. W. Schroeder, W. J. Tremaine, and D. M. Ilstrup, "Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study," The New England Journal of Medicine, vol. 317, no. 26, pp. 1625-1629, 1987.
8. G. DHaens, W. J. Sandborn, B. G. Feagan et al. , "A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis," Gastroenterology, vol. 132, no. 2, pp. 763-786, 2007.
9. M. Arabul, M. Celik, O. Aslan et al. , "Hepcidin as a predictor of disease severity in acute pancreatitis: a single center prospective study," Hepato-Gastroenterology, vol. 60, no. 123, pp. 595-600, 2013.
10. M. A. Abdel-Khalek, A. M. El-Barbary, S. A.-M. Essa, and A. S. Ghobashi, "Serum hepcidin: a direct link between anemia of inflammation and coronary artery atherosclerosis in patients with rheumatoid arthritis,"The Journal of Rheumatology, vol. 38, no. 10, pp. 2153-2159, 2011.
11. R. J. Basseri, E. Nemeth, M. E. Vassilaki et al. , "Hepcidin is a key mediator of anemia of inflammation in Crohns disease," Journal of Crohns and Colitis, vol. 7, no. 8, pp. e286-e291, 2013.
12. J. Arnold, A. Sangwaiya, B. Bhatkal, F. Geoghegan, and M. Busbridge, "Hepcidin and inflammatory bowel disease: dual role in host defence and iron homoeostasis," European Journal of Gastroenterology and Hepatology, vol. 21, no. 4, pp. 425-429, 2009.
13. P. Oustamanolakis, I. E. Koutroubakis, I. Messaritakis, N. Malliaraki, A. Sfiridaki, and E. A. Kouroumalis, "Serum hepcidin and prohepcidin concentrations in inflammatory bowel disease," European Journal of Gastroenterology and Hepatology, vol. 23, no. 3, pp. 262-268, 2011.
14. L. Wang, E. Trebicka, Y. Fu et al. , "The bonemorphogenetic protein- hepcidin axis as a therapeutic target in inflammatory bowel disease," Inflammatory Bowel Diseases, vol. 18, no. 1, pp. 112-119, 2012.
15. J. Nagy, L. Lakner, V. S. Poór et al. , "Serum prohepcidin levels in chronic inflammatory bowel diseases," Journal of Crohns and Colitis, vol. 4, no. 6, pp. 649-653, 2010.
16. G. Semrin, D. S. Fishman, A. Bousvaros et al. , "Impaired intestinal iron absorption in Crohns disease correlates with disease activity and markers of inflammation," Inflammatory Bowel Diseases, vol. 12, no. 12, pp. 1101-1106, 2006.