Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis

Journal of the American Chemical Society

Volumn 137, Issue 1, 2015, Pages 86-89

  Wong, Fong T ^b   Hotta, Kinya ^a,d   Chen, Xi ^a   Fang, Minyi ^a   Watanabe, Kenji ^c   Kim, Chu Young ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b Agency for Science   (Singapore)

^c UNIVERSITY OF SHIZUOKA   (Japan)

^d UNIVERSITY OF NOTTINGHAM MALAYSIA CAMPUS   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CELL IMMOBILIZATION; CYCLIZATION; ETHERS; HYDROLASES; IONOPHORES; KETONES;

C-TERMINAL DOMAINS; CYCLIC ETHER; EPOXIDE HYDROLASES; EPOXIDE OPENINGS; IONOPHORE ANTIBIOTIC; NATURAL PRODUCTS; POLYKETIDES; TETRAHYDROPYRAN;

CRYSTAL STRUCTURE;

EPOXIDE HYDROLASE; LASALOCID; POLYETHER; BIOLOGICAL PRODUCT; ETHER DERIVATIVE; POLYMER;

ARTICLE; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYCLIZATION; HYDROGEN BOND; PHYLOGENETIC TREE; PROTEIN INTERACTION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; METABOLISM;

BIOLOGICAL PRODUCTS; CYCLIZATION; EPOXIDE HYDROLASES; ETHERS; LASALOCID; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; POLYMERS;

EID: 84921038461     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja511374k     Document Type: Article

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