Incidence of hospital admissions due to adverse drug reactions in France: The EMIR study

Fundamental and Clinical Pharmacology

Volumn 29, Issue 1, 2015, Pages 106-111

  Bénard Laribière, Anne ^a   Miremont Salamé, Ghada ^a,b   Pérault Pochat, Marie Christine ^c   Noize, Pernelle ^a,b   Haramburu, Françoise ^a,b   Andrejak, Michel ^d   Autret Leca, Elisabeth ^d   Babai, Samy ^d   Baldin, Bernadette ^d   Baricault, Sophie ^d   Barjhoux, Claude Elisabeth ^d   Bavoux, Françoise ^e   de Paul, Vincent ^d   Bernard, Nathalie ^d   Berthet, Stéphanie ^d   Beyens, Marie Noëlle ^d   Biour, Michel ^f   Blayac, Jean Pierre ^d   Boyer, Marie ^d   Brenet Dufour, Valérie ^d   Brocvieille, Hélène ^g   Bruel, Meri ^d   Carlhant, Dominique ^d   Caron, Jacques ^d   Chichmanian, Rose Marie ^d   Chiffoleau, Anne ^d   Colin, Frédérique ^d   Coquerel, Antoine ^d   Cosserat, Françoise ^d   Coullet, Valérie ^d   Darsonval Spiesser, Astrid ^d   Davani, Siamak ^d   Default, Anne ^d   Devémy, Marie ^d   Drici, Milou Daniel ^d   Droz Perroteau, Cécile ^d   Eftekhari, Pirayeh ^h   Eschalier, Alain ^d   Favrelière, Sylvie ^d   Fournier Choma, Christine ^d   Germain, Marie Laure ^d   Gillet, Pierre ^d   Ginisty, Sixtine ^h   Gosselet, Julien ^d   Grandvuillemin, Aurélie ^d   Gras Champel, Valérie ^d   Guitton, Emmanuelle ^d   Guy, Claire ^d   Hilaire Buys, Dominique ^d   Horowicz, Sylvie ^h   Imbs, Jean Louis ^d   Jantzem, Hélène ^d   Jean Pastor, Marie Josèphe ^d   Jolimoy, Geneviève ^d   Jolliet, Pascale ^d   Jonville Béra, Annie Pierre ^d   Jové, Jérémy ^d   Kantelip, Jean Pierre ^d   Kopp, Michel ^d   Lainé Cessac, Pascale ^d   Lamaison, Dominique ^d   Laroche, Marie Laure ^d   Lassalle, Régis ^d   Lates, Silviana ^d   Le Louet, Hervé ^g   Lebeller, Christine ^d   Lebrun Vignes, Bénédicte ⁱ   Liège, Ludovic ^d   Lillo Le Louet, Agnès ^d   Mallaret, Michel ^d   Massy, Nathalie ^d   Merle, Louis ^d   Mismetti, Patrick ^d   Montastruc, Jean Louis ^d   Mosquet, Brigitte ^d   Mounier, Geneviève ^d   Noblet, Catherine ^d   Nouaille, Yves ^d   Novella, Jean Luc ^d   Olivier, Pascale ^d   Ollagnier, Michel ^d   Ouk, Tavarak ^d   Parry, Eve ^d   Petitpain, Nadine ^d   Peyrière, Hélène ^d   Pinzani, Véronique ^d   Polard, Elisabeth ^d   Riché, Christian ^d   Rougeot, Estelle ^d   Schlienger, Jean Louis ^d   Sgro, Catherine ^d   Silvoz, Nathalie ^d   Spreux, Anne ^d   Tebacher, Martine ^d   Thierry, Maryne ^e   Thuillez, Christian ^d   Tréchot, Philippe ^d   Trenque, Thierry ^d   Valnet Rabier, Marie Blanche ^d   Vial, Thierry ^d   Vion, Virginie ^d   Welsch, Marie ^d   more..

^a BORDEAUX UNIVERSITY HOSPITAL   (France)

^b INSERM   (France)

^c POITIERS UNIVERSITY HOSPITAL   (France)

^d NONE   (France)

^e Saint Louis Institute Paris Diderot   (France)

^f Saint Antoine Paris University Hospital Center   (France)

^g Service d'Immunologie Clinique   (France)

^h HÔPITAL FERNAND WIDAL   (France)

ⁱ PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Adverse drug reactions; Hospitalization; Incidence; Pharmacovigilance; Prospective studies

Indexed keywords

ANALGESIC AGENT; ANTICOAGULANT AGENT; ANTINEOPLASTIC AGENT; ANTIVITAMIN K; ANXIOLYTIC AGENT; DIURETIC AGENT; HYPNOTIC AGENT; NEUROLEPTIC AGENT;

ADOLESCENT; ADULT; ADVERSE DRUG REACTION; AGED; ARTICLE; BLEEDING; BRAIN HEMORRHAGE; CAUSE OF DEATH; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DRUG SAFETY; DRUG SURVEILLANCE PROGRAM; FEMALE; FOLLOW UP; FRANCE; GASTROINTESTINAL DISEASE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MEDICATION ERROR; MULTICENTER STUDY; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PUBLIC HOSPITAL; SELF MEDICATION; VASCULAR DISEASE; DRUG INTERACTION; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; MIDDLE AGED; YOUNG ADULT;

ADOLESCENT; ADULT; ADVERSE DRUG REACTION REPORTING SYSTEMS; AGED; ANTICOAGULANTS; DRUG INTERACTIONS; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; FRANCE; HOSPITALIZATION; HUMANS; INCIDENCE; MIDDLE AGED; PROSPECTIVE STUDIES; YOUNG ADULT;

EID: 84921025968     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/fcp.12088     Document Type: Article

References (18)

1. Alexopoulou A., Dourakis S.P., Mantzoukis D. et al. Adverse drug reactions as a cause of hospital admissions: a 6-month experience in a single center in Greece. Eur. J. Intern. Med. (2008) 19 505-510.
2. Carrasco-Garrido P., de Andres L.A., Barrera V.H., de Miguel G.A., Jimenez-Garcia R. Trends of adverse drug reactions related-hospitalizations in Spain (2001-2006). BMC Health Serv. Res. (2010) 10 287.
3. Einarson T.R. Drug-related hospital admissions. Ann. Pharmacother. (1993) 27 832-840.
4. Kongkaew C., Noyce P.R., Ashcroft D.M. Hospital admissions associated with adverse drug reactions: a systematic review of prospective observational studies. Ann. Pharmacother. (2008) 42 1017-1025.
5. Lazarou J., Pomeranz B.H., Corey P.N. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA (1998) 279 1200-1205.
6. Moore N., Lecointre D., Noblet C., Mabille M. Frequency and cost of serious adverse drug reactions in a department of general medicine. Br. J. Clin. Pharmacol. (1998) 45 301-308.
7. Patel H., Bell D., Molokhia M. et al. Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998-2005. BMC Clin. Pharmacol. (2007) 7 9.
8. Pirmohamed M., James S., Meakin S. et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ (2004) 329 15-19.
9. Pouyanne P., Haramburu F., Imbs J.L., Begaud B. Admissions to hospital caused by adverse drug reactions: cross sectional incidence study. French Pharmacovigilance Centres. BMJ (2000) 320 1036.
10. Roughead E.E., Gilbert A.L., Primrose J.G., Sansom L.N. Drug-related hospital admissions: a review of Australian studies published 1988-1996. Med. J. Aust. (1998) 168 405-408.
11. van der Hooft C.S., Dieleman J.P., Siemes C. et al. Adverse drug reaction-related hospitalisations: a population-based cohort study. Pharmacoepidemiol. Drug Saf. (2008) 17 365-371.
12. van der Hooft C.S., Sturkenboom M.C., van Grootheest K., Kingma H.J., Stricker B.H. Adverse drug reaction-related hospitalisations: a nationwide study in The Netherlands. Drug Saf. (2006) 29 161-168.
13. Haramburu F., Miremont-Salamé G., Bénard A., Perault M.C., Imbs J. Incidence of hospital admissions due to adverse drug reactions: the EMIR study. Fundam. Clin. Pharmacol. (2008) 22 20.
14. Miremont-Salamé G., Bénard-Laribière A., Perault Pochat M., Imbs J., Haramburu F. Hospital admissions due to adverse drug reactions: EMIR, a Nationwide Study. Drug Saf. (2008) 31 885.
15. World Health Organization. Safety of medicines - a guide to detecting and reporting adverse drug reactions - why health professionals need to take action. WHO/EDM/QSM/2002.2. Available from: http://apps.who.int/medicinedocs/en/d/Jh2992e/1.html-Jh2992e [accessed 11 December 2013].
16. Olivier P., Caron J., Haramburu F. et al. Validation of a measurement scale: example of a French Adverse Drug Reactions Preventability Scale. Therapie (2005) 60 39-45.
17. Agence nationale de sécurité du médicament et des produits de santé. Les anticoagulants en France en 2012: Etat des lieux et surveillance. Available from: http://ansm.sante.fr/content/download/42641/553644/version/1/file/Rapport_Anticoagulants_Juillet2012.pdf [accessed 27 May 2014].
18. Gonsalves W.I., Pruthi R.K., Patnaik M.M. The new oral anticoagulants in clinical practice. Mayo Clin. Proc. (2013) 88 495-511.