Frequency and cost of serious adverse drug reactions in a department of general medicine

British Journal of Clinical Pharmacology

Volumn 45, Issue 3, 1998, Pages 301-308

  Moore, Nicholas ^a   Lecointre, Dominique ^c   Noblet, Catherine ^b   Mabille, Michel ^c  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b ROUEN UNIVERSITY HOSPITAL   (France)

^c LE HAVRE HOSPITAL   (France)

Author keywords

Adverse drug reactions

Indexed keywords

ANTIBIOTIC AGENT; ANTIHYPERTENSIVE AGENT; DIGOXIN; FLUOXETINE; HEPARIN CALCIUM; INSULIN; LOW MOLECULAR WEIGHT HEPARIN; NEUROLEPTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; TRICYCLIC ANTIDEPRESSANT AGENT; TRIHEXYPHENIDYL; VILOXAZINE;

ADOLESCENT; ADULT; ADVERSE DRUG REACTION; AGE; AGED; ARTICLE; CLINICAL TRIAL; FEMALE; GENERAL PRACTICE; HEALTH CARE COST; HOSPITAL ADMISSION; HOSPITAL COST; HOSPITALIZATION; HUMAN; INCIDENCE; INTERNAL MEDICINE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; SEX DIFFERENCE; SUICIDE ATTEMPT;

ADOLESCENT; ADULT; ADVERSE DRUG REACTION REPORTING SYSTEMS; AGED; AGED, 80 AND OVER; DRUG THERAPY; FEMALE; FRANCE; HOSPITALS, GENERAL; HUMANS; INCIDENCE; LENGTH OF STAY; MALE; MIDDLE AGED; PREVALENCE; PROSPECTIVE STUDIES;

EID: 0031941382     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1998.00667.x     Document Type: Article

References (32)

1. Einarson TR. Drug-related hospital admissions. Ann Pharmacother 1993; 27: 832-840.
2. Hallas J, Gram LF, Grodum E, et al. Drug related admissions to medical wards: a population based survey. Br J Clin Pharmacol 1992; 33: 61-68.
3. Classen DC, Pestotnik SL, Evans RS, Burke JP. Computerized surveillance of adverse drug events in hospital patients. JAMA 1991; 266: 2847-2851.
4. Harb GE, Alldredge BK, Coleman R, Jacobson MA. Pharmacoepidemiology of adverse drug reactions in hospitalized patients with human immunodeficiency virus disease. J Acquir Immune Defic Syndr 1993; 6: 919-926.
5. Moore N, Briffaut C, Noblet C, Augustin-Normand C, Thuillez C. Indirect drug related costs. Lancet 1995; 345: 588-589.
6. Rawlins MD, Thompson JW. Pathogenesis of adverse drug reactions. In Textbook of Adverse Drug Reactions, ed Davies DM. Oxford University Press, 1977: pp 10-31.
7. Dictionnaire Vidal, OVP editions, Paris, 1996.
8. Hallas J, Harvald B, Gram LF, et al. Drug related hospital admissions: the role of definitions and intensity of data collection, and the possibility of prevention. J Intern Med 1990; 228: 83-90.
9. Chrischilles EA, Segar ET, Wallace RB. Self-reported adverse drug reactions and related resource use. A study of community-dwelling persons 65 years of age and older [see comments]. Ann Intern Med 1992; 117: 634-640.
10. Prince BS, Goetz CM, Rihn TL, Olsky M. Drug-related emergency department visits and hospital admissions. Am J Hosp Pharm 1992; 49: 1696-1700.
11. Schneider JK, Mion LC, Frengley JD. Adverse drug reactions in an elderly outpatient population. Am J Hosp Pharm 1992; 49: 90-96.
12. Kernan W, Castellsague J, Perlman GD, Ostfeld A. Incidence of hospitalization for digitalis toxicity among elderly Americans. Am J Med 1994; 96: 426-431.
13. Warren JL, McBean AM, Hass SL, Babish JD. Hospitalizations with adverse events caused by digitalis therapy among elderly Medicare beneficiaries. Arch Intern Med 1994; 154: 1482-1487.
14. Mahdyoon H, Battilana G, Rosman H, Goldstein S, Gheorghiade M. The evolving pattern of digoxin intoxication: observations at a large urban hospital from 1980 to 1988. Am Heart J 1990; 120: 1189-1194.
15. Chan TY, Chan JC, Tomlinson B, Critchley JA. Adverse reactions to drugs as a cause of admissions to a general teaching hospital in Hong Kong. Drug Safety 1992; 7: 235-240.
16. Col N, Fanale JE, Kronholm P. The role of medication noncompliance and adverse drug reactions in hospitalizations of the elderly. Arch Intern Med 1990; 150: 841-845.
17. Garijo B, de Abajo FJ, Castro MA, Lopo CR, Carcas A, Frias J. Hospitalizations because of drugs: a prospective study. Revista Clinica Espanola. 1991; 188: 7-12.
18. Hallas J, Davidsen O, Grodum E, Damsbo N, Gram LF. Drug-related illness as a cause of admission to a department of respiratory medicine. Respiration. 1992; 59: 30-34.
19. Hallas J, Haghfelt T, Gram LF, Grodum E, Damsbo N. Drug related admissions to a cardiology department: frequency and avoidability. J Intern Med 1990; 228: 379-384.
20. Hallas J, Harvald B, Worm J, et al. Drug related hospital admissions. Results from an intervention program. Eur J Clin Pharmacol 1993; 45: 199-203.
21. Hallas J, Jensen KB, Grodum E, Damsbo N, Gram LF. Drug-related admissions to a department of medical gastroenterology. The role of self-medicated and prescribed drugs. Scand J Gastroenterol 1991; 26: 174-180.
22. Hallas J, Worm J, Beck-Nielsen J, et al. Drug related events and drug utilization in patients admitted to a geriatric hospital department. Dan Med Bull 1991; 38: 417-420.
23. Lin SH, Lin MS. A survey on drug-related hospitalization in a community teaching hospital. Int J Clin Pharmacol Ther Toxicol 1993; 31: 66-69.
24. Lindley CM, Tully MP, Paramsothy V, Tallis RC. Inappropriate medication is a major cause of adverse drug reactions in elderly patients. Age Ageing 1992; 21: 294-300.
25. Smucker WD, Kontak JR. Adverse drug reactions causing hospital admission in an elderly population: experience with a decision algorithm. J Am Board Fam Pract 1990; 3: 105-109.
26. van Kraaij DJ, Haagsma CJ, Go IH, Gribnau FW. Drug use and adverse drug reactions in 105 elderly patients admitted to a general medical ward. Neth J Med 1994; 44: 166-173.
27. Carbonin P, Pahor M, Bernabei R, Sgadari A. Is age an independent risk fator of adverse drug reactions in hospitalized medical patients? J Am Geriatr Soc 1991; 39: 1093-1099.
28. Foreman MD, Theis SL, Anderson MA. Adverse events in the hospitalized elderly. Clin Nurs Res 1993; 2: 360-370.
29. O'Neil AC, Petersen LA, Cook EF, Bates DW, Lee TH, Brennan TA. Physician reporting compared with medical-record review to identify adverse medical events. Ann Intern Med 1993; 119: 370-376.
30. Classen DC, Pestotnik SL, Evans RS, Lloyd JF, Burke JP. Adverse drug events in hospitalized patients: excess length of stay, extra costs, and attributable mortality. JAMA 1997; 277: 301-306.
31. Bates DW, Spell N, Cullen DJ, et al. The costs of adverse drug events in hospitalized patients. JAMA, 1997; 277: 307-311.
32. Dartnell JG, Anderson RP, Chohan V, et al. Hospitalisation for adverse event related to drug therapy: incidence, avoidability and costs. Med J Aust 1996; 164: 659-662.