Adverse drug reaction-related hospitalisations: A population-based cohort study

Pharmacoepidemiology and Drug Safety

Volumn 17, Issue 4, 2008, Pages 365-371

  van der Hooft, Cornells S ^a,b,c   Dieleman, Jeanne P ^a   Siemes, Claire ^a   Aarnoudse, Albert Jan L H J ^a,b   Verhamme, Katia M C ^a   Strieker, Bruno H C H ^a,b   Sturkenboom, Miriam C J M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Inspectorate for Health Care   (Netherlands)

^c MEDICAL CENTER LEEUWARDEN   (Netherlands)

Author keywords

Adverse effects; Causality; Hospitalization; Incidence; Prevalence; Public health

Indexed keywords

ACETYLSALICYLIC ACID; AGENTS ACTING ON THE GENITAL SYSTEM; ANTIARRHYTHMIC AGENT; ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIDIABETIC AGENT; ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; ANTINEOPLASTIC AGENT; ANTIPARASITIC AGENT; ANTIVITAMIN K; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARDIOVASCULAR AGENT; CENTRAL NERVOUS SYSTEM AGENTS; CONTRACEPTIVE AGENT; CORTICOSTEROID; CYTOTOXIC AGENT; DERMATOLOGICAL AGENT; DIURETIC AGENT; HEMATOLOGIC AGENT; IMMUNOSUPPRESSIVE AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE DERIVATIVE; PROKINETIC AGENT; RESPIRATORY TRACT AGENT; SEX HORMONE; UNINDEXED DRUG; URINARY TRACT AGENT;

ADOLESCENT; ADULT; ADVERSE DRUG REACTION; AGED; AGING; ALGORITHM; ARTICLE; BRADYCARDIA; BRAIN HEMORRHAGE; COHORT ANALYSIS; DATA BASE; DISEASE SEVERITY; DRUG FATALITY; DRUG SAFETY; ELECTRONIC MEDICAL RECORD; FEBRILE NEUTROPENIA; FEMALE; GASTROINTESTINAL HEMORRHAGE; GENERAL PRACTITIONER; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; HYPOTENSION; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; NETHERLANDS; PHARMACOEPIDEMIOLOGY; POPULATION RESEARCH; PRACTICE GUIDELINE; PREVALENCE; PRIORITY JOURNAL; UNSPECIFIED SIDE EFFECT; WORLD HEALTH ORGANIZATION; DRUG THERAPY; HEALTH SURVEY; MEDICAL RECORD; METHODOLOGY; MIDDLE AGED; STATISTICS;

ADOLESCENT; ADULT; AGED; COHORT STUDIES; DRUG THERAPY; FEMALE; HOSPITALIZATION; HUMANS; MALE; MEDICAL RECORDS SYSTEMS, COMPUTERIZED; MIDDLE AGED; NETHERLANDS; PHARMACOEPIDEMIOLOGY; POPULATION SURVEILLANCE; PREVALENCE;

EID: 42149085112     PISSN: 10538569     EISSN: 10991557     Source Type: Journal    
DOI: 10.1002/pds.1565     Document Type: Article

References (33)

1. Kohn LT, Corrigan JM, Donaldson MS. To Err is Human: Building a Safer Health System. Institute of Medicine: Washington DC, 2000.
2. Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 1998; 279(15): 1200-1205.
3. Roughead EE, Gilbert AL, Primrose JG, Sansom LN. Drug-related hospital admissions: a review of Australian studies published 1988-1996. Med J Aust 1998; 169(8): 405-408.
4. Beijer HJ, de Blaey CJ. Hospitalisations caused by adverse drug reactions (ADR): a meta-analysis of observational studies. Pharam World Sci 2002; 24(2): 46-54.
5. Muehlberger N, Schneeweiss S, Hasford J. Adverse drug reaction monitoring-cost and benefit considerations. Part 1: frequency of adverse drug reactions causing hospital admissions. Pharmacoepidemiol Drug Saf 1997; 6(Suppl 3): S71-S77.
6. Onder G, Pedone C, Landi F, et al. Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). J Am Geriatr Soc 2002; 50(12): 1962-1968.
7. Pirmohamed M, James S, Meakin S, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. Br Med J 2004; 329(7456): 15-19.
8. Hallas J, Gram LF, Grodurn E, et al. Drug related admissions to medical wards: a population based survey. Br J Clin Pharmacol 1992; 33(1): 61-68.
9. Schneeweiss S, Hasford J, Gottler M, Hoffmann A, Riethling AK, Avom J. Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study. Eur J Clin Pharmacol 2002; 58(4): 285-291.
10. van der Lei J, Duisterhout JS, Westerhof HP, et al. The introduction of computer-based patient records in The Netherlands. Ann Intern Med 1993; 119(10): 1036-1041.
11. Vlug AE, van der Lei J, Mosseveld BM, et al. Postmarketing surveillance based on electronic patient records: the EPCI project. Methods Inf Med 1999; 38(4-5): 339-344.
12. Lamberts H, Wood M, Hoftnans-Okkes IM. International primary care classifications: the effect of fifteen years of evolution. Fam Pract 1992; 9(3): 330-339.
13. World Health Organization. International drug monitoring. The role of the hospital. World Health Organ Tech Rep Ser 1969; 425: 5-24.
14. Morimoto T, Gandhi TK, Seger AC, Hsieh TC, Bates DW. Adverse drug events and medication enmrs: detection and classification methods. Qual Saf Health Care 2004; 13(4): 306-314.
15. Hallas J, Harvald B, Gram LF, et al. Drug related hospital admissions: the role of definitions and intensity of data collection, and the possibility of prevention. J Intern Med 1990; 228(2): 83-90.
16. van der Hooft CS, Sturkenboom MC, van Grootheest K, Kingma HJ, Stricker BH. Adverse drug reaction-related hospitalisations: a nationwide study in The Netherlands. Drug Saf 2006; 29(2): 161-168.
17. Mannesse CK, Derkx FH, de Ridder MA, Man in't Veld AJ, vander Cammen TJ. Contribution of adverse drug reactions to hospital admission of older patients. Age Ageing 2000; 29(1): 35-39.
18. Hallas J, Haghfelt T. Gram LF, Grodum E, Damsbo N. Drug related adirdssions to a cardiology department; frequency and avoidability. J Intern Med 1990; 228(4): 379-384.
19. Mjorndal T, Boman MD, Hagg S, et al. Adverse drug reactions as a cause for admissions to a department of internal medicine. Pharmacoepidemiol Drug Saf 2002; 11(1): 65-72.
20. van Kraaij DJ, Haagsma CJ, Go IH, Gribnau FW. Drug use and adverse drug reactions in 105 elderly patients admitted to a general medical ward. Neth J Med 1994; 44(5): 166473.
21. McDonnell PJ, Jacobs MR. Hospital admissions resulting from preventable adverse drug reactions. Ann Pharmacother 2002; 36(9): 1331-1336.
22. Moore N, Lecointre D, Noblet C, Mabille M. Frequency and cost of serious adverse drug reactions in a department of general medicine. Br J Clin Pharmacol 1998; 45(3): 301-308.
23. Lagnaoui R, Moore N, Fach J, Longy-Boursier M, Begaud B. Adverse drug reactions in a department of systemic diseases-oriented internal medicine: prevalence, incidence, direct costs and avoidability. Eur J Clin Pharmacol 2000; 56(2): 181-186.
24. Green CF, Mottram DR, Rowe PH, Pirmohamed M. Adverse drug reactions as a cause of admission to an acute medical assessment unit: a pilot study. J Clin Pharm Ther 2000; 25(5): 355-361.
25. Bates DW, Leape LL, Petrycki S. Incidence and preventability of adverse drug events in hospitalized adults. J Gen Intern Med 1993; 8(6): 289-294.
26. Gholami K, Shalvid G. Factors associated with preventability, predictability, and severity of adverse drug reactions. Ann Pharmacother 1999; 33(2): 236-240.
27. Pearson TF, Pittman DG, Longley JM, Grapes ZT, Vigliotti DJ, Mullis SR. Factors associated with preventable adverse drug reactions. Am J Hosp Pharm 1994; 51(18): 2268-2272.
28. Schumock GT, Thornton JP. Focusing on the preventability of adverse drug reactions. Hosp Pharm 1992; 27(6): 538.
29. Buurma H, de Smet PA, van den Hoff OP, Egberts AC. Nature, frequency and determinants of prescription modifications in Dutch community pharmacies. Br J Clin Pharmacol 2001; 52(l): 85-891.
30. Pouyanne P, Haramburu F, Imbs JL, Begaud B. Admissions to hospital caused by adverse drug reactions: cross sectional incidence study. French Pharmacovigilance Centres. Br Med J 2000; 320(7241): 1036.
31. Capuano A, Motola G, Russo F, et al. Adverse drug events in two emergency departments in Naples, Italy: an observational study. Pharmacol Res 2004; 50(6): 631-6316.
32. Naranjo CA, BustD U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981; 30(2): 239-245.
33. Kramer MS, Leventhal JM, Hutchinson TA, Feinstein AR. An algorithm for the operational assessment of adverse drug reactions. I. Background, description, and instructions for use. JAMA 1979; 242(7): 623-632.