Chemoprotection of MNNG-initiated gastric cancer in rats using Iranian propolis

Archives of Iranian Medicine

Volumn 18, Issue 1, 2015, Pages 18-23

  Alizadeh, Ali Mohammad ^a   Afrouzan, Houshang ^b   Dinparast Djadid, Navid ^c   Sawaya, Alexandra C H F ^d   Azizian, Saleh ^a   Hemmati, Hamid Reza ^a   Mohagheghi, Mohammad Ali ^a   Erfani, Soheila ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Honeybee Department   (Iran)

^c PASTEUR INSTITUTE OF IRAN   (Iran)

^d UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Apoptosis; Gastric cancer; Iranian propolis; Rat

Indexed keywords

AROMATIC CARBOXYLIC ACID; BETA CATENIN; METHYLNITRONITROSOGUANIDINE; PHENOL DERIVATIVE; PROPOLIS; PROTEIN BCL 2; ANTINEOPLASTIC AGENT; CTNNB1 PROTEIN, RAT; PROTEIN BAX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; CANCER GRADING; CANCER INCIDENCE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; MASS SPECTROMETRY; METASTASIS; NONHUMAN; PROTEIN EXPRESSION; RAT; SCORING SYSTEM; STOMACH CANCER; TUMOR VOLUME; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ADENOCARCINOMA; ANIMAL; APOPTOSIS; CELL PROLIFERATION; CHEMICALLY INDUCED; DRUG EFFECTS; EXPERIMENTAL NEOPLASM; GASTRIC MUCOSA; IRAN; METABOLISM; PATHOLOGY; STOMACH TUMOR; WISTAR RAT;

ADENOCARCINOMA; ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BETA CATENIN; CELL PROLIFERATION; GASTRIC MUCOSA; IRAN; MALE; METHYLNITRONITROSOGUANIDINE; NEOPLASMS, EXPERIMENTAL; PROPOLIS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; STOMACH NEOPLASMS;

EID: 84920999052     PISSN: 10292977     EISSN: 17353947     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Pisani P, Parkin DM, Bray F, Ferlay J. Estimates of the worldwide mortality from 25 cancers in 1990. IntJ Cancer. 1999; 83: 18-29.
2. Lima B, Tapia A, Luna L, Fabani MP, Schmeda-Hirschmann G, Po- dio, et al. Main flavonoids, DPPH activity, and metal content allow determination of the geographical origin of propolis from the Province of San Juan (Argentina). J Agric FoodChem. 2009; 57: 2691-2698.
3. Marcucci MC. Propolis: chemical composition, biological properties and therapeutic activity. Apidologie. 1995; 26: 83-99.
4. Josipovic P, Orsolic N. Cytotoxicity of polyphenolic/flavonoid compounds in a leukaemia cell culture. ArhHigRada Toksikol. 2008; 59: 299-308.
5. Siegfried A, Dirk R, Uwe L. Propolis and Some of its Constituents Down-Regulate DNA Synthesis and Inflammatory Cytokine Production but Induce TGF-pi Production of Human Immune Cells. Z Naturforsch. 2003; 58: 580-589.
6. Xiang D, Wang D, He Y, Xie J, Zhong Z, Li Z, et al. Caffeic acid phenethyl ester induces growth arrest and apoptosis of colon cancer cells via the beta-catenin/T-cell factor signaling. Anticancer Drugs. 2006; 17: 753-762.
7. Ribeiro U Jr, Safatle-Ribeiro AV. Caffeic acid phenethyl ester may be a promising adjuvant treatment in gastric cancer. J Clin Gastroenterol. 2007; 41: 871-873.
8. Orsi RO, Sforcin JM, Funari SRC, Bankova V. Effects of propolis from Brazil and Bulgaria on bactericidal activity of macrophages against Salmonella typhimurium. Int Immunopharmacol. 2005; 5: 359-368.
9. Gonsales GZ, Orsi RO, Fernandes Junior A, Rodrigues P, Funari SRC. Antibacterial activity of propolis collected in different regions of Brazil. J Venom Toxins. 2006; 12: 276-284.
10. Kiyota E, Mazzafera P, Sawaya AC. Analysis of soluble lignin in sugarcane by ultrahigh performance liquid chromatography-tandem mass spectrometry with a do-it-yourself oligomer database. Anal Chem. 2012; 84: 7015-7020.
11. Gardana C, Scaglianti M, Pietta P, Simonetti P. Analysis of the poly- phenolic fraction of propolis from different sources by liquid chro- matography-tandem mass spectrometry. JPharm BiomedAnal. 2007; 45: 390-399.
12. Abe M, Yamashita S, Kuramoto T, Hirayama Y, Tsukamoto T, Ohta T, et al. Global expression analysis of Nmethyl-N'-nitro-N- nitrosoguanidine-induced rat stomach carcinomas using oligonucleotide microarrays. Carcinogenesis. 2003; 24: 861-867.
13. Alizadeh AM, Khaniki M, Azizian S, Mohaghgheghi MA, Sadeghiza- deh M, Najafi F. Chemoprevention of azoxymethane-initiated colon cancer in rat by using a novel polymeric nanocarrier-curcumin. Eur J Pharmacol. 2012; 689: 226-232.
14. Alizadeh AM, Faghihi M, Khori V, Sohanaki H, Pourkhalili K, Mo- hammadghasemi F, et al. Oxytocin protects cardiomyocytes from apoptosis induced by ischemia-reperfusion in rat heart: role of mitochondrial ATP-dependent potassium channel and permeability transition pore. Peptides. 2012; 36: 71-77.
15. Padmavathi R, Senthilnathan P, Chodon D, Sakthisekaran D. Therapeutic effect of paclitaxel and propolis on lipid peroxidation and antioxidant system in 7, 12 dimethyl benz(a)anthracene-induced breast cancer in female Sprague Dawley rats. Life Sci. 2006; 78: 2820-2825.
16. Khalil ML. Biological activity of bee propolis in health and disease. Asian Pac J Cancer Prev. 2006; 7: 22-31.
17. Tsao Y. Chemistry and biochemistry of dietary polyphenols. Nutrients. 2010; 2: 1231-1246.
18. Chen MJ, Chang WH, Lin CC, Liu CY, Wang TE, Chu CH, et al. Caffeic acid phenethyl ester induces apoptosis of human pancreatic cancer cells involving caspase and mitochondrial dysfunction. Pan- creatology. 2008; 8: 566-576.
19. Hishikawa K, Nakaki T, Fujita T. Oral flavonoid supplementation attenuates atherosclerosis development in apolipoprotein E-deficient Mice. Arterioscler Thromb Vasc Biol. 2005; 25: 442-446.
20. Nagaoka T, Banskota AH, Tezuka Y, Midorikawa K, Matsushige K, Kadota S. Caffeic acid phenethyl ester (CAPE) analogues: potent nitric oxide inhibitors from the Netherlands propolis. Biol Pharm Bull. 2003; 26: 487-491.
21. Nagata S, Golstein P. The Fas death factor. Science. 1995; 267: 1449-1456.
22. Oyama T, Yamada Y, Hata K, Tomita H, Hirata A, Sheng H, et al. Further upregulation of beta-catenin/Tcf transcription is involved in the development of macroscopic tumors in the colon of ApcMin/+ mice. Carcinogenesis. 2008; 29: 666-672.
23. Chen CN, Weng MS, Wu CL, Lin JK. Comparison of radical scavenging activity, cytotoxic effects and apoptosis induction in human melanoma cells by Taiwanese propolis from different sources. Evid BasedComplement AlternatMed. 2004; 1: 175-185.
24. Chen CN, Wu CL, Lin JK. Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwanese propolis. Cancer Lett. 2007; 245: 218-231.