Chemoprevention of azoxymethane-initiated colon cancer in rat by using a novel polymeric nanocarrier-curcumin

European Journal of Pharmacology

Volumn 689, Issue 1-3, 2012, Pages 226-232

  Alizadeh, Ali Mohammad ^a   Khaniki, Mahmood ^b   Azizian, Saleh ^a   Mohaghgheghi, Mohammad Ali ^a   Sadeghizadeh, Majid ^c   Najafi, Farhood ^d,e  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TARBIAT MODARES UNIVERSITY   (Iran)

^d INSTITUTE FOR COLOR SCIENCE AND TECHNOLOGY   (Iran)

^e UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Colon cancer; Curcumin; Polymeric nanocarrier; Rat

Indexed keywords

AZOXYMETHANE; BETA CATENIN; CURCUMIN; NANOPARTICLE; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER PREVENTION; CELL NUCLEUS; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; COLON CANCER; CONTROLLED STUDY; CYTOPLASM; EXPERIMENTAL RAT; GOBLET CELL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TISSUE DISTRIBUTION; TUMOR LOCALIZATION; TUMOR VOLUME;

ANIMALS; ANTICARCINOGENIC AGENTS; AZOXYMETHANE; CHEMOPREVENTION; COLONIC NEOPLASMS; CURCUMIN; DRUG CARRIERS; MALE; NANOPARTICLES; POLYMERS; RATS; RATS, WISTAR;

EID: 84864280534     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.06.016     Document Type: Article

References (25)

1. B.B. Aggarwal, C. Sundaram, N. Malani, and H. Ichikawa Curcumin: the Indian solid gold Adv. Exp. Med. Biol. 595 2007 1 75
2. P. Anand, A.B. Kunnumakkara, R.A. Newman, and B.B. Aggarwal Bioavailability of curcumin: problems and promises Mol. Pharm. 4 2007 807 818
3. P. Anand, H.B. Nair, B. Sung, A.B. Kunnumakkara, V.R. Yadav, R.R. Tekmal, and B.B. Aggarwal Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo Biochem. Pharmacol. 79 2010 330 338
4. E. Babaei, M. Sadeghizadeh, Z.M. Hassan, M.A. Feizi, F. Najafi, and S.M. Hashemi Dendrosomal curcumin significantly suppresses cancer cell proliferation in vitro and in vivo Int. Immunopharmacol. 12 2012 226 234
5. J.B. Baell, and D.C. Huang Prospects for targeting Bcl-2 family of proteins to develop cytotoxic drugs Biochem. Pharmacol. 64 2002 851 863 (Pubitemid 35232259)
6. S. Bisht, G. Feldmann, S. Soni, R. Ravi, C. Karikar, A. Maitra, and A. Maitra Polymeric nanoparticle-encapsulated curcumin (nanocurcumin): a novel strategy for human cancer therapy J. Nanobiotechnol. 5 2007 3
7. F.A. Haggar, and R.P. Boushey Colorectal cancer epidemiology: incidence, mortality, survival, and risk factors Clin. Colon. Rectal. Surg. 22 2009 191 197
8. P.A. Hall, P.J. Coates, B. Ansari, and D. Hopwood Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis J. Cell. Sci. 107 1994 3569 3577
9. C. Ireson, S. Orr, D.J. Jones, R. Verschoyle, C.K. Lim, J.L. Luo, L. Howells, S. Plummer, R. Jukes, M. Williams, W.P. Steward, and A. Gescher Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production Cancer Res. 61 2001 1058 1064 (Pubitemid 32174425)
10. M. Jaattela Multiple cell death pathways as regulators of tumour initiation and progression Oncogene 23 2004 2746 2756 (Pubitemid 38638838)
11. T. Kawamori, R. Lubet, V.E. Steele, G.J. Kelloff, R.B. Kaskey, C.V. Rao, and B.S. Reddy Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer Cancer Res. 59 1999 597 601 (Pubitemid 29076056)
12. G.J. Kelloff, J.A. Crowell, V.E. Steele, R.A. Lubet, W.A. Malone, C.W. Boone, L. Kopelovich, E.T. Hawk, R. Lieberman, J.A. Lawrence, I. Ali, J.L. Viner, and C.C. Sigman Progress in cancer chemoprevention: development of diet-derived chemopreventive agents J. Nutr. 130 2000 467S 471S (Pubitemid 30073775)
13. Y. Kwon, and B.A. Magnuson Age-related differential responses to curcumin-induced apoptosis during the initiation of colon cancer in rats Food. Chem. Toxicol. 47 2009 377 385
14. F.D. Ledley Nonviral gene therapy: the promise of genes as pharmaceutical products Hum. Gene. Ther. 6 1995 1129 1144
15. K. Letchford, R. Liggins, and H. Burt Solubilization of hydrophobic drugs by methoxy poly(ethylene glycol)-block-polycaprolactone diblock copolymer micelles: theoretical and experimental data and correlations J. Pharm. Sci. 97 2008 1179 1190
16. C. Mohanty, S. Acharya, A.K. Mohanty, F. Dilnawaz, and S.K. Sahoo Curcumin-encapsulated MePEG/PCL diblock copolymeric micelles: a novel controlled delivery vehicle for cancer therapy Nanomedicine (Lond) 5 2010 433 449
17. T. Oyama, Y. Yamada, K. Hata, H. Tomita, A. Hirata, H. Sheng, A. Hara, H. Aoki, T. Kunisada, S. Yamashita, and H. Mori Further upregulation of beta-catenin/Tcf transcription is involved in the development of macroscopic tumors in the colon of ApcMin/ mice Carcinogenesis 29 2008 666 672 (Pubitemid 351404885)
18. P. Polakis Wnt signaling and cancer Genes. Dev. 14 2000 1837 1851 (Pubitemid 30639518)
19. F. Pourasgari, S. Ahmadian, A.H. Salmanian, M.N. Sarbolouki, and M. Massumi Low cytotoxicity effect of dendrosome as an efficient carrier for rotavirus VP2 gene transferring into a human lung cell line: dendrosome, as a novel intranasally gene porter Mol. Biol. Rep. 36 2009 105 109
20. C.V. Rao, T. Kawamori, R. Hamid, and B.S. Reddy Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor Carcinogenesis 20 1999 641 644 (Pubitemid 29151301)
21. G. Sa, and T. Das Anti cancer effects of curcumin: cycle of life and death Cell. Div. 3 2008 14
22. M. Sadeghizadeh, R. Ranjbar, M. Damaghi, L. Khaki, M.N. Sarbolouki, F. Najafi, S. Parsaee, A.A. Ziaee, M. Massumi, W. Lubitz, and P. Kudela Dendrosomes as novel gene porters - III J. Chem. Technol. Biotechnol. 83 2008 912 920 (Pubitemid 351771714)
23. M.N. Sarbolouki, M. Sadeghizadeh, M.M. Yaghoobi, A. Karami, and T. Lohrasbi Dendrosomes: a novel family of vehicles for transfection and therapy J. Chem. Technol. Biotechnol. 75 2000 919 922
24. J. Shaikh, D.D. Ankola, V. Beniwal, D. Singh, and M.N. Kumar Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. J Eur. J. Pharm. Sci. 37 2009 223 230
25. K. Sou, S. Inenaga, S. Takeoka, and E. Tsuchida Loading of curcumin into macrophages using lipid-based nanoparticles Int. J. Pharm. 352 2008 287 293