메뉴 건너뛰기




Volumn 35, Issue 2, 2015, Pages 442-456

The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150

Author keywords

A kinase anchoring protein; AMPAR; LTP; Palmitoylation; Recycling endosome; Trafficking

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; ENZYME; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PALMITOYL ACYLTRANSFERASE; UNCLASSIFIED DRUG; ACYLTRANSFERASE; DHHC2 PROTEIN, RAT;

EID: 84920997601     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2243-14.2015     Document Type: Article
Times cited : (56)

References (54)
  • 1
    • 84862325147 scopus 로고    scopus 로고
    • Regulation of AMPA receptor trafficking and synaptic plasticity
    • CrossRef Medline
    • Anggono V, Huganir RL (2012) Regulation of AMPA receptor trafficking and synaptic plasticity. Curr Opin Neurobiol 22:461-469. CrossRef Medline
    • (2012) Curr Opin Neurobiol , vol.22 , pp. 461-469
    • Anggono, V.1    Huganir, R.L.2
  • 2
    • 58849099053 scopus 로고    scopus 로고
    • A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors
    • CrossRef Medline
    • Bhattacharyya S, Biou V, Xu W, Schlüter O, Malenka RC (2009) A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors. Nat Neurosci 12:172-181. CrossRef Medline
    • (2009) Nat Neurosci , vol.12 , pp. 172-181
    • Bhattacharyya, S.1    Biou, V.2    Xu, W.3    Schlüter, O.4    Malenka, R.C.5
  • 4
    • 36849089658 scopus 로고    scopus 로고
    • Functional compartmentalization of endosomal trafficking for the synaptic delivery ofAMPA receptors during long-term potentiation
    • CrossRef Medline
    • Brown TC, Correia SS, Petrok CN, Esteban JA (2007) Functional compartmentalization of endosomal trafficking for the synaptic delivery ofAMPA receptors during long-term potentiation. J Neurosci 27:13311-13315. CrossRef Medline
    • (2007) J Neurosci , vol.27 , pp. 13311-13315
    • Brown, T.C.1    Correia, S.S.2    Petrok, C.N.3    Esteban, J.A.4
  • 5
  • 6
    • 80053007224 scopus 로고    scopus 로고
    • Palmitoylation targets AKAP79 to lipid rafts and promotes its regulation of the calcium sensitive adenylyl cyclase type 8
    • CrossRef Medline
    • Delint-Martinez I, Willoughby D, Hammond GV, Ayling LJ, Cooper DM (2011) Palmitoylation targets AKAP79 to lipid rafts and promotes its regulation of the calcium sensitive adenylyl cyclase type 8. J Biol Chem 286:32962-32975. CrossRef Medline
    • (2011) J Biol Chem , vol.286 , pp. 32962-32975
    • Delint-Martinez, I.1    Willoughby, D.2    Hammond, G.V.3    Ayling, L.J.4    Cooper, D.M.5
  • 7
    • 0032522719 scopus 로고    scopus 로고
    • Membrane-targeting sequences on AKAP79 bind phosphatidylinositol-4, 5-bisphosphate
    • CrossRef Medline
    • Dell’Acqua ML, Faux MC, Thorburn J, Thorburn A, Scott JD (1998) Membrane-targeting sequences on AKAP79 bind phosphatidylinositol-4, 5-bisphosphate. EMBO J 17:2246-2260. CrossRef Medline
    • (1998) EMBO J , vol.17 , pp. 2246-2260
    • Dell’Acqua, M.L.1    Faux, M.C.2    Thorburn, J.3    Thorburn, A.4    Scott, J.D.5
  • 8
    • 0033639083 scopus 로고    scopus 로고
    • Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting
    • CrossRef Medline
    • Ehlers MD (2000) Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting. Neuron 28:511-525. CrossRef Medline
    • (2000) Neuron , vol.28 , pp. 511-525
    • Ehlers, M.D.1
  • 9
    • 0037374587 scopus 로고    scopus 로고
    • Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system
    • EhlersMD, CrossRef Medline
    • EhlersMD (2003) Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system. Nat Neurosci 6:231-242. CrossRef Medline
    • (2003) Nat Neurosci , vol.6 , pp. 231-242
  • 10
    • 0034627757 scopus 로고    scopus 로고
    • Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering
    • CrossRef Medline
    • El-Husseini AE, Craven SE, Chetkovich DM, Firestein BL, Schnell E, Aoki C, Bredt DS (2000) Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering. J Cell Biol 148:159-172. CrossRef Medline
    • (2000) J Cell Biol , vol.148 , pp. 159-172
    • El-Husseini, A.E.1    Craven, S.E.2    Chetkovich, D.M.3    Firestein, B.L.4    Schnell, E.5    Aoki, C.6    Bredt, D.S.7
  • 12
    • 84866411994 scopus 로고    scopus 로고
    • The balance between receptor recycling and trafficking toward lysosomes determines synaptic strength during long-term depression
    • CrossRef Medline
    • Fernández-Monreal M, Brown TC, Royo M, Esteban JA (2012) The balance between receptor recycling and trafficking toward lysosomes determines synaptic strength during long-term depression. J Neurosci 32:13200-13205. CrossRef Medline
    • (2012) J Neurosci , vol.32 , pp. 13200-13205
    • Fernández-Monreal, M.1    Brown, T.C.2    Royo, M.3    Esteban, J.A.4
  • 13
    • 33746217840 scopus 로고    scopus 로고
    • Ionic mechanisms of autorhythmic firing in rat cerebellar Golgi cells
    • CrossRef Medline
    • Forti L, Cesana E, Mapelli J, D’Angelo E (2006) Ionic mechanisms of autorhythmic firing in rat cerebellar Golgi cells. J Physiol 574:711-729. CrossRef Medline
    • (2006) J Physiol , vol.574 , pp. 711-729
    • Forti, L.1    Cesana, E.2    Mapelli, J.3    D’Angelo, E.4
  • 14
    • 77956247700 scopus 로고    scopus 로고
    • Long-term potentiation-dependent spine enlargement requires synaptic Ca2_-permeable AMPA receptors recruited by CaM-kinase I
    • CrossRef Medline
    • Fortin DA, Davare MA, Srivastava T, Brady JD, Nygaard S, Derkach VA, Soderling TR (2010) Long-term potentiation-dependent spine enlargement requires synaptic Ca2_-permeable AMPA receptors recruited by CaM-kinase I. J Neurosci 30:11565-11575. CrossRef Medline
    • (2010) J Neurosci , vol.30 , pp. 11565-11575
    • Fortin, D.A.1    Davare, M.A.2    Srivastava, T.3    Brady, J.D.4    Nygaard, S.5    Derkach, V.A.6    Soderling, T.R.7
  • 15
    • 10444253304 scopus 로고    scopus 로고
    • Identification of PSD-95 palmitoylating enzymes
    • CrossRef Medline
    • Fukata M, Fukata Y, Adesnik H, Nicoll RA, Bredt DS (2004) Identification of PSD-95 palmitoylating enzymes. Neuron 44:987-996. CrossRef Medline
    • (2004) Neuron , vol.44 , pp. 987-996
    • Fukata, M.1    Fukata, Y.2    Adesnik, H.3    Nicoll, R.A.4    Bredt, D.S.5
  • 16
    • 77249134163 scopus 로고    scopus 로고
    • Protein palmitoylation in neuronal development and synaptic plasticity
    • CrossRef Medline
    • Fukata Y, Fukata M (2010) Protein palmitoylation in neuronal development and synaptic plasticity. Nat Rev Neurosci 11:161-175. CrossRef Medline
    • (2010) Nat Rev Neurosci , vol.11 , pp. 161-175
    • Fukata, Y.1    Fukata, M.2
  • 17
    • 84880590079 scopus 로고    scopus 로고
    • Local palmitoylation cycles define activity-regulated postsynaptic subdomains
    • CrossRef Medline
    • Fukata Y, Dimitrov A, Boncompain G, Vielemeyer O, Perez F, Fukata M (2013) Local palmitoylation cycles define activity-regulated postsynaptic subdomains. J Cell Biol 202:145-161. CrossRef Medline
    • (2013) J Cell Biol , vol.202 , pp. 145-161
    • Fukata, Y.1    Dimitrov, A.2    Boncompain, G.3    Vielemeyer, O.4    Perez, F.5    Fukata, M.6
  • 18
    • 0037104782 scopus 로고    scopus 로고
    • Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin
    • Medline
    • Gomez LL, Alam S, Smith KE, Horne E, Dell’Acqua ML (2002) Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin. J Neurosci 22:7027-7044. Medline
    • (2002) J Neurosci , vol.22 , pp. 7027-7044
    • Gomez, L.L.1    Alam, S.2    Smith, K.E.3    Horne, E.4    Dell’Acqua, M.L.5
  • 19
    • 79957617680 scopus 로고    scopus 로고
    • The palmitoyl transferase DHHC2 targets a dynamic membrane cycling pathway: Regulation by a C-terminal domain
    • CrossRef Medline
    • Greaves J, Carmichael JA, Chamberlain LH (2011) The palmitoyl transferase DHHC2 targets a dynamic membrane cycling pathway: regulation by a C-terminal domain. Mol Biol Cell 22:1887-1895. CrossRef Medline
    • (2011) Mol Biol Cell , vol.22 , pp. 1887-1895
    • Greaves, J.1    Carmichael, J.A.2    Chamberlain, L.H.3
  • 20
    • 34047178403 scopus 로고    scopus 로고
    • Phospholipase C is required for changes in postsynaptic structure and function associated with NMDA receptordependent long-term depression
    • CrossRef Medline
    • Horne EA, Dell’Acqua ML (2007) Phospholipase C is required for changes in postsynaptic structure and function associated with NMDA receptordependent long-term depression. J Neurosci 27:3523-3534. CrossRef Medline
    • (2007) J Neurosci , vol.27 , pp. 3523-3534
    • Horne, E.A.1    Dell’Acqua, M.L.2
  • 22
    • 77956190591 scopus 로고    scopus 로고
    • A calcineurin/AKAP complex is required for NMDA receptor-dependent long-term depression
    • CrossRef Medline
    • Jurado S, Biou V, Malenka RC (2010) A calcineurin/AKAP complex is required for NMDA receptor-dependent long-term depression. Nat Neurosci 13:1053-1055. CrossRef Medline
    • (2010) Nat Neurosci , vol.13 , pp. 1053-1055
    • Jurado, S.1    Biou, V.2    Malenka, R.C.3
  • 25
    • 79952209617 scopus 로고    scopus 로고
    • Mechanisms and function of dendritic exocytosis
    • CrossRef Medline
    • Kennedy MJ, Ehlers MD (2011) Mechanisms and function of dendritic exocytosis. Neuron 69:856-875. CrossRef Medline
    • (2011) Neuron , vol.69 , pp. 856-875
    • Kennedy, M.J.1    Ehlers, M.D.2
  • 26
    • 77951913551 scopus 로고    scopus 로고
    • Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines
    • CrossRef Medline
    • Kennedy MJ, Davison IG, Robinson CG, Ehlers MD (2010) Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines. Cell 141:524-535. CrossRef Medline
    • (2010) Cell , vol.141 , pp. 524-535
    • Kennedy, M.J.1    Davison, I.G.2    Robinson, C.G.3    Ehlers, M.D.4
  • 27
    • 59649114125 scopus 로고    scopus 로고
    • Synaptic AMPA receptor plasticity and behavior
    • CrossRef Medline
    • Kessels HW, Malinow R (2009) Synaptic AMPA receptor plasticity and behavior. Neuron 61:340-350. CrossRef Medline
    • (2009) Neuron , vol.61 , pp. 340-350
    • Kessels, H.W.1    Malinow, R.2
  • 28
    • 33644560354 scopus 로고    scopus 로고
    • Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation
    • CrossRef Medline
    • Kopec CD, Li B, Wei W, Boehm J, Malinow R (2006) Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation. J Neurosci 26:2000-2009. CrossRef Medline
    • (2006) J Neurosci , vol.26 , pp. 2000-2009
    • Kopec, C.D.1    Li, B.2    Wei, W.3    Boehm, J.4    Malinow, R.5
  • 29
    • 77951225186 scopus 로고    scopus 로고
    • DHHC5 interacts with PDZ domain 3 of postsynaptic density-95 (PSD-95) protein and plays a role in learning and memory
    • CrossRef Medline
    • Li Y, Hu J, Höfer K, Wong AM, Cooper JD, Birnbaum SG, Hammer RE, Hofmann SL (2010) DHHC5 interacts with PDZ domain 3 of postsynaptic density-95 (PSD-95) protein and plays a role in learning and memory. J Biol Chem 285:13022-13031. CrossRef Medline
    • (2010) J Biol Chem , vol.285 , pp. 13022-13031
    • Li, Y.1    Hu, J.2    Höfer, K.3    Wong, A.M.4    Cooper, J.D.5    Birnbaum, S.G.6    Hammer, R.E.7    Hofmann, S.L.8
  • 30
    • 33845794047 scopus 로고    scopus 로고
    • Palmitoylation: Policing protein stability and traffic
    • CrossRef Medline
    • Linder ME, Deschenes RJ (2007) Palmitoylation: policing protein stability and traffic. Nat Rev Mol Cell Biol 8:74-84. CrossRef Medline
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 74-84
    • Linder, M.E.1    Deschenes, R.J.2
  • 31
    • 84873142329 scopus 로고    scopus 로고
    • Mechanism and function of DHHC S-acyltransferases
    • CrossRef Medline
    • Linder ME, Jennings BC (2013) Mechanism and function of DHHC S-acyltransferases. Biochem Soc Trans 41:29-34. CrossRef Medline
    • (2013) Biochem Soc Trans , vol.41 , pp. 29-34
    • Linder, M.E.1    Jennings, B.C.2
  • 32
    • 0035132869 scopus 로고    scopus 로고
    • Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons
    • CrossRef Medline
    • Lu W, Man H, Ju W, Trimble WS, MacDonald JF, Wang YT (2001) Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons. Neuron 29:243-254. CrossRef Medline
    • (2001) Neuron , vol.29 , pp. 243-254
    • Lu, W.1    Man, H.2    Ju, W.3    Trimble, W.S.4    Macdonald, J.F.5    Wang, Y.T.6
  • 34
    • 70350752569 scopus 로고    scopus 로고
    • AMPA receptor incorporation into synapses during LTP: The role of lateral movement and exocytosis
    • CrossRef Medline
    • Makino H, Malinow R (2009) AMPA receptor incorporation into synapses during LTP: the role of lateral movement and exocytosis. Neuron 64:381-390. CrossRef Medline
    • (2009) Neuron , vol.64 , pp. 381-390
    • Makino, H.1    Malinow, R.2
  • 35
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: An embarrassment of riches
    • CrossRef Medline
    • Malenka RC, Bear MF (2004) LTP and LTD: an embarrassment of riches. Neuron 44:5-21. CrossRef Medline
    • (2004) Neuron , vol.44 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 36
    • 0035708355 scopus 로고    scopus 로고
    • Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons
    • CrossRef Medline
    • Matsuzaki M, Ellis-Davies GC, Nemoto T, Miyashita Y, Iino M, Kasai H (2001) Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons. Nat Neurosci 4:1086-1092. CrossRef Medline
    • (2001) Nat Neurosci , vol.4 , pp. 1086-1092
    • Matsuzaki, M.1    Ellis-Davies, G.C.2    Nemoto, T.3    Miyashita, Y.4    Iino, M.5    Kasai, H.6
  • 38
    • 33646830442 scopus 로고    scopus 로고
    • Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins
    • CrossRef Medline
    • Ohno Y, Kihara A, Sano T, Igarashi Y (2006) Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. Biochim Biophys Acta 1761:474-483. CrossRef Medline
    • (2006) Biochim Biophys Acta , vol.1761 , pp. 474-483
    • Ohno, Y.1    Kihara, A.2    Sano, T.3    Igarashi, Y.4
  • 39
    • 7044267351 scopus 로고    scopus 로고
    • Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity
    • CrossRef Medline
    • Okamoto K, Nagai T, Miyawaki A, Hayashi Y (2004) Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Nat Neurosci 7:1104-1112. CrossRef Medline
    • (2004) Nat Neurosci , vol.7 , pp. 1104-1112
    • Okamoto, K.1    Nagai, T.2    Miyawaki, A.3    Hayashi, Y.4
  • 40
    • 77955478311 scopus 로고    scopus 로고
    • CaMKII triggers the diffusional trapping of surface AMPARs through phosphorylation of Stargazin
    • CrossRef Medline
    • Opazo P, Labrecque S, Tigaret CM, Frouin A, Wiseman PW, De Koninck P, Choquet D (2010) CaMKII triggers the diffusional trapping of surface AMPARs through phosphorylation of Stargazin. Neuron 67:239-252. CrossRef Medline
    • (2010) Neuron , vol.67 , pp. 239-252
    • Opazo, P.1    Labrecque, S.2    Tigaret, C.M.3    Frouin, A.4    Wiseman, P.W.5    De Koninck, P.6    Choquet, D.7
  • 41
    • 4644287672 scopus 로고    scopus 로고
    • Recycling endosomes supply AMPA receptors for LTP
    • CrossRef Medline
    • Park M, Penick EC, Edwards JG, Kauer JA, Ehlers MD (2004) Recycling endosomes supply AMPA receptors for LTP. Science 305:1972-1975. CrossRef Medline
    • (2004) Science , vol.305 , pp. 1972-1975
    • Park, M.1    Penick, E.C.2    Edwards, J.G.3    Kauer, J.A.4    Ehlers, M.D.5
  • 42
    • 33845396840 scopus 로고    scopus 로고
    • Plasticity-induced growth of dendritic spines by exocytic trafficking from recycling endosomes
    • CrossRef Medline
    • Park M, Salgado JM, Ostroff L, Helton TD, Robinson CG, Harris KM, Ehlers MD (2006) Plasticity-induced growth of dendritic spines by exocytic trafficking from recycling endosomes. Neuron 52:817-830. CrossRef Medline
    • (2006) Neuron , vol.52 , pp. 817-830
    • Park, M.1    Salgado, J.M.2    Ostroff, L.3    Helton, T.D.4    Robinson, C.G.5    Harris, K.M.6    Ehlers, M.D.7
  • 43
    • 68349117289 scopus 로고    scopus 로고
    • Endocytic trafficking and recycling maintain a pool of mobile surface AMPA receptors required for synaptic potentiation
    • CrossRef Medline
    • Petrini EM, Lu J, Cognet L, Lounis B, Ehlers MD, Choquet D (2009) Endocytic trafficking and recycling maintain a pool of mobile surface AMPA receptors required for synaptic potentiation. Neuron 63:92-105. CrossRef Medline
    • (2009) Neuron , vol.63 , pp. 92-105
    • Petrini, E.M.1    Lu, J.2    Cognet, L.3    Lounis, B.4    Ehlers, M.D.5    Choquet, D.6
  • 44
    • 67449113568 scopus 로고    scopus 로고
    • Regulation of postsynaptic structure and function by an A-kinase anchoring proteinmembrane-associated guanylate kinase scaffolding complex
    • CrossRef Medline
    • Robertson HR, Gibson ES, Benke TA, Dell’Acqua ML (2009) Regulation of postsynaptic structure and function by an A-kinase anchoring proteinmembrane-associated guanylate kinase scaffolding complex. J Neurosci 29:7929-7943. CrossRef Medline
    • (2009) J Neurosci , vol.29 , pp. 7929-7943
    • Robertson, H.R.1    Gibson, E.S.2    Benke, T.A.3    Dell’Acqua, M.L.4
  • 46
    • 79956131603 scopus 로고    scopus 로고
    • AKAP signaling complexes in regulation of excitatory synaptic plasticity
    • CrossRef Medline
    • Sanderson JL, Dell’Acqua ML (2011) AKAP signaling complexes in regulation of excitatory synaptic plasticity. Neuroscientist 17:321-336. CrossRef Medline
    • (2011) Neuroscientist , vol.17 , pp. 321-336
    • Sanderson, J.L.1    Dell’Acqua, M.L.2
  • 47
    • 84867758439 scopus 로고    scopus 로고
    • AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors
    • CrossRef Medline
    • Sanderson JL, Gorski JA, Gibson ES, Lam P, Freund RK, Chick WS, Dell’Acqua ML (2012) AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors. J Neurosci 32:15036-15052. CrossRef Medline
    • (2012) J Neurosci , vol.32 , pp. 15036-15052
    • Sanderson, J.L.1    Gorski, J.A.2    Gibson, E.S.3    Lam, P.4    Freund, R.K.5    Chick, W.S.6    Dell’Acqua, M.L.7
  • 48
    • 34548436564 scopus 로고    scopus 로고
    • The postsynaptic architecture of excitatory synapses: A more quantitative view
    • CrossRef Medline
    • Sheng M, Hoogenraad CC (2007) The postsynaptic architecture of excitatory synapses: a more quantitative view. Annu Rev Biochem 76:823-847. CrossRef Medline
    • (2007) Annu Rev Biochem , vol.76 , pp. 823-847
    • Sheng, M.1    Hoogenraad, C.C.2
  • 49
    • 0037092436 scopus 로고    scopus 로고
    • Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression
    • Medline
    • Tavalin SJ, Colledge M, Hell JW, Langeberg LK, Huganir RL, Scott JD (2002) Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression. J Neurosci 22:3044-3051. Medline
    • (2002) J Neurosci , vol.22 , pp. 3044-3051
    • Tavalin, S.J.1    Colledge, M.2    Hell, J.W.3    Langeberg, L.K.4    Huganir, R.L.5    Scott, J.D.6
  • 50
    • 84873167786 scopus 로고    scopus 로고
    • Palmitoylation-dependent regulation of glutamate receptors and their PDZ domain-containing partners
    • CrossRef Medline
    • Thomas GM, Huganir RL (2013) Palmitoylation-dependent regulation of glutamate receptors and their PDZ domain-containing partners. Biochem Soc Trans 41:72-78. CrossRef Medline
    • (2013) Biochem Soc Trans , vol.41 , pp. 72-78
    • Thomas, G.M.1    Huganir, R.L.2
  • 51
    • 84863012668 scopus 로고    scopus 로고
    • Palmitoylation by DHHC5/8 targets GRIP1 to dendritic endosomes to regulate AMPA-R trafficking
    • CrossRef Medline
    • Thomas GM, Hayashi T, Chiu SL, Chen CM, Huganir RL (2012) Palmitoylation by DHHC5/8 targets GRIP1 to dendritic endosomes to regulate AMPA-R trafficking. Neuron 73:482-496. CrossRef Medline
    • (2012) Neuron , vol.73 , pp. 482-496
    • Thomas, G.M.1    Hayashi, T.2    Chiu, S.L.3    Chen, C.M.4    Huganir, R.L.5
  • 52
    • 84884547415 scopus 로고    scopus 로고
    • DHHC8-dependent PICK1 palmitoylation is required for induction of cerebellar long-term synaptic depression
    • CrossRef Medline
    • Thomas GM, Hayashi T, Huganir RL, Linden DJ (2013) DHHC8-dependent PICK1 palmitoylation is required for induction of cerebellar long-term synaptic depression. J Neurosci 33:15401-15407. CrossRef Medline
    • (2013) J Neurosci , vol.33 , pp. 15401-15407
    • Thomas, G.M.1    Hayashi, T.2    Huganir, R.L.3    Linden, D.J.4
  • 53
    • 84863888017 scopus 로고    scopus 로고
    • Homeostatic synaptic plasticity: Local and global mechanisms for stabilizing neuronal function
    • CrossRef Medline
    • Turrigiano G (2012) Homeostatic synaptic plasticity: local and global mechanisms for stabilizing neuronal function. Cold Spring Harb Perspect Biol 4:a005736. CrossRef Medline
    • (2012) Cold Spring Harb Perspect Biol , vol.4
    • Turrigiano, G.1
  • 54
    • 61449242763 scopus 로고    scopus 로고
    • Protein acyl thioesterases (Review)
    • CrossRef Medline
    • Zeidman R, Jackson CS, Magee AI (2009) Protein acyl thioesterases (review). Mol Membr Biol 26:32-41. CrossRef Medline
    • (2009) Mol Membr Biol , vol.26 , pp. 32-41
    • Zeidman, R.1    Jackson, C.S.2    Magee, A.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.