Patient selection for stroke endovascular therapy-DWI-ASPECTS thresholds should vary among age groups:Insights from the RECOST study

American Journal of Neuroradiology

Volumn 36, Issue 1, 2015, Pages 32-39

  Daniere F ^a   Lobotesis, K ^b   Machi, P ^a   Eker, O ^a   Mourand, I ^a   Riquelme, C ^a   Ayrignac, X ^a   Vendrell, J F ^a   Gascou, G ^a   Fendeleur, J ^a   Dargazanli, C ^a   Schaub, R ^c   Brunel, H ^d   Arquizan, C ^a   Bonafe A ^a   Costalat, Vincent ^a  

^a MONTPELLIER UNIVERSITY HOSPITAL   (France)

^b CHARING CROSS HOSPITAL   (United Kingdom)

^c UNIV MONTPELLIER   (France)

^d TIMONE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOLYTIC AGENT; GADOLINIUM PENTETATE;

ADULT; AGED; ARTERY DISSECTION; ARTERY INJURY; ARTERY SPASM; ARTICLE; BLOOD VESSEL OCCLUSION; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CLINICAL EVALUATION; CLINICAL PROTOCOL; DIFFUSION WEIGHTED IMAGING; EMBOLISM; ENDOVASCULAR SURGERY; FEMALE; FIBRINOLYTIC THERAPY; GROUPS BY AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MECHANICAL THROMBECTOMY; MEMBRANE DAMAGE; MIDDLE AGED; MORTALITY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PATIENT SELECTION; PERCUTANEOUS THROMBECTOMY; PROGNOSIS; PROSPECTIVE STUDY; STENT RETRIEVER; STROKE PATIENT; TREATMENT OUTCOME; VERY ELDERLY; PROCEDURES; STROKE; THROMBECTOMY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ENDOVASCULAR PROCEDURES; FEMALE; HUMANS; MALE; MIDDLE AGED; PATIENT SELECTION; PROGNOSIS; STROKE; THROMBECTOMY; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84920983008     PISSN: 01956108     EISSN: 1936959X     Source Type: Journal    
DOI: 10.3174/ajnr.A4104     Document Type: Article

References (48)

1. Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics: 2011 update: A report from the American Heart Association. Circulation 2011;123:e18-e209
2. Miniño AM, Murphy SL, Xu J, et al. Deaths: Final data for 2008. Natl Vital Stat Rep 2011;59:1-126
3. Kelly-Hayes M, Beiser A, Kase CS, et al. The influence of gender and age on disability following ischemic stroke: The Framingham study. J Stroke Cerebrovasc Dis 2003;12:119-26
4. Truelsen T, Piechowski-Jozwiak B, Bonita R, et al. Stroke incidence and prevalence in Europe: A review of available data. Eur J Neurol 2006;13:581-98
5. Hacke W, Kaste M, Bluhmki E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008;359:1317-29
6. Tissue plasminogen activator for acute ischemic stroke: The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med 1995;333:1581-87
7. Longstreth WT Jr, Katz R, Tirschwell DL, et al. Intravenous tissue plasminogen activator and stroke in the elderly. Am J Emerg Med 2010;28:359-63
8. Berrouschot J, Rother J, Glahn J, et al. Outcome and severe hemorrhagic complications of intravenous thrombolysis with tissue plasminogen activator in very old (>or =80 years) stroke patients. Stroke 2005;36:2421-25
9. Engelter ST, Bonati LH, Lyrer PA. Intravenous thrombolysis in stroke patients of > or =80 versus < 80 years of age: a systematic review across cohort studies. Age Ageing 2006;35:572-80
10. Heuschmann PU, Kolominsky-Rabas PL, Misselwitz B, et al. Predictors of in-hospital mortality and attributable risks of death after ischemic stroke: The German Stroke Registers Study Group. Arch Intern Med 2004;164:1761-68
11. Wardlaw JM, Murray V, Berge E, et al. Recombinant tissue plasminogen activator for acute ischaemic stroke: An updated systematic review and meta-analysis. Lancet 2012;379:2364-72
12. García-Caldentey J, Alonso de Lecinana M, Simal P, et al. Intravenous thrombolytic treatment in the oldest old. Stroke Res Treat 2012;2012:923676
13. Smith WS, Sung G, Saver J, et al. Mechanical thrombectomy for acute ischemic stroke: Final results of the Multi MERCI trial. Stroke 2008;39:1205-12
14. Rha JH, Saver JL. The impact of recanalization on ischemic stroke outcome: A meta-analysis. Stroke 2007;38:967-73
15. Mazighi M, Serfaty JM, Labreuche J, et al. Comparison of intravenous alteplase with a combined intravenous-endovascular approach in patients with stroke and confirmed arterial occlusion (RECANALISE study): A prospective cohort study. Lancet Neurol 2009;8:802-09
16. Roth C, Papanagiotou P, Behnke S, et al. Stent-assisted mechanical recanalization for treatment of acute intracerebral artery occlusions. Stroke 2010;41:2559-67
17. Penumbra Pivotal Stroke Trial Investigators. The Penumbra Pivotal Stroke Trial: Safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke 2009;40:2761-68
18. Saver JL, Jahan R, Levy EI, et al. Solitaire flow restoration device versus the Merci retriever in patients with acute ischaemic stroke (SWIFT): A randomised, parallel-group, non-inferiority trial. Lancet 2012;380:1241-49
19. Castaño C, Dorado L, Guerrero C, et al. Mechanical thrombectomy with the Solitaire AB device in large artery occlusions of the anterior circulation: A pilot study. Stroke 2010;41:1836-40
20. Costalat V, Machi P, Lobotesis K, et al. Rescue, combined, and stand-alone thrombectomy in the management of large vessel occlusion stroke using the Solitaire device: A prospective 50-patient single-center study: Timing, safety, and efficacy. Stroke 2011;42:1929 -35
21. Machi P, Costalat V, Lobotesis K, et al. Solitaire FR thrombectomy system: Immediate results in 56 consecutive acute ischemic stroke patients. J Neurointerv Surg 2012;4:62-66
22. Pexman JH, Barber PA, Hill MD, et al. Use of the Alberta Stroke Program Early CT Score (ASPECTS) for assessing CT scans in patients with acute stroke. AJNR Am J Neuroradiol 2001;22:1534-42
23. Barber PA, Demchuk AM, Zhang J, et al. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy: ASPECTS Study Group-Alberta Stroke Programme Early CT Score. Lancet 2000; 355:1670-74
24. Butcher KS, Parsons M, MacGregor L, et al. Refining the perfusiondiffusion mismatch hypothesis. Stroke 2005;36:1153-59
25. Wittsack HJ, Ritzl A, Fink GR, et al. MR imaging in acute stroke: Diffusion-weighted and perfusion imaging parameters for predicting infarct size. Radiology 2002;222:397-403
26. Hacke W, Kaste M, Fieschi C, et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: The European Cooperative Acute Stroke Study (ECASS). JAMA 1995;274:1017-25
27. Hacke W, Kaste M, Fieschi C, et al. Randomised double-blind placebo- controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II): Second European- Australasian Acute Stroke Study Investigators. Lancet 1998;352: 1245-51
28. Furlan A, Higashida R, Wechsler L, et al. Intra-arterial prourokinase for acute ischemic stroke: The PROACT II study-A randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. JAMA 1999;282:2003-11
29. IMS II Trial Investigators. The Interventional Management of Stroke (IMS) II study. Stroke 2007;38:2127-35
30. Rankin J. Cerebral vascular accidents in patients over the age of 60 II. Prognosis. Scott Med J 1957;2:200-15
31. van Swieten JC, Koudstaal PJ, Visser MC, et al. Interobserver agreement for the assessment of handicap in stroke patients. Stroke 1988;19:604-07
32. Saqqur M, Uchino K, Demchuk AM, et al. Site of arterial occlusion identified by transcranial Doppler predicts the response to intravenous thrombolysis for stroke. Stroke 2007;38:948-54
33. Linfante I, Llinas RH, Selim M, et al. Clinical and vascular outcome in internal carotid artery versus middle cerebral artery occlusions after intravenous tissue plasminogen activator. Stroke 2002;33: 2066-71
34. Molina CA, Alexandrov AV, Demchuk AM, et al. Improving the predictive accuracy of recanalization on stroke outcome in patients treated with tissue plasminogen activator. Stroke 2004;35:151-56
35. Pereira VM, Gralla J, Davalos A, et al. Prospective, multicenter, single- arm study of mechanical thrombectomy using Solitaire flow restoration in acute ischemic stroke. Stroke 2013;44:2802-07
36. Loh Y, Kim D, Shi ZS, et al. Higher rates of mortality but not morbidity follow intracranial mechanical thrombectomy in the elderly. AJNR Am J Neuroradiol 2010;31:1181-85
37. Adams HP Jr, Davis PH, Leira EC, et al. Baseline NIH Stroke Scale score strongly predicts outcome after stroke: A report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST). Neurology 1999;53: 126-31
38. Costalat V, Lobotesis K, Machi P, et al. Prognostic factors related to clinical outcome following thrombectomy in ischemic stroke (RECOST study): 50 patients prospective study. Eur J Radiol 2012; 81:4075-82
39. Dávalos A, Pereira VM, Chapot R, et al. Retrospective multicenter study of Solitaire FR for revascularization in the treatment of acute ischemic stroke. Stroke 2012;43:2699-705
40. Epstein SE, Lassance-Soares RM, Faber JE, et al. Effects of aging on the collateral circulation, and therapeutic implications. Circulation 2012;125:3211-19
41. Hecht N, He J, Kremenetskaia I, et al. Cerebral hemodynamic reserve and vascular remodeling in C57/BL6 mice are influenced by age. Stroke 2012;43:3052-62
42. Di Carlo A, Lamassa M, Pracucci G, et al. Stroke in the very old: Clinical presentation and determinants of 3-month functional outcome: A European perspective-European BIOMED Study of Stroke Care Group. Stroke 1999;30:2313-19
43. Denti L, Scoditti U, Tonelli C, et al. The poor outcome of ischemic stroke in very old people: A cohort study of its determinants. J Am Geriatr Soc 2010;58:12-17
44. Yoo AJ, Chaudhry ZA, Nogueira RG, et al. Infarct volume is a pivotal biomarker after intra-arterial stroke therapy. Stroke 2012;43: 1323-30
45. Yoo AJ, Verduzco LA, Schaefer PW, et al. MRI-based selection for intra-arterial stroke therapy: Value of pretreatment diffusionweighted imaging lesion volume in selecting patients with acute stroke who will benefit from early recanalization. Stroke 2009; 40:2046-54
46. Sanák D, Nosal V, Horak D, et al. Impact of diffusion-weighted MRI-measured initial cerebral infarction volume on clinical outcome in acute stroke patients with middle cerebral artery occlusion treated by thrombolysis. Neuroradiology 2006;48: 632-39
47. Nezu T, Koga M, Kimura K, et al. Pretreatment ASPECTS on DWI predicts 3-month outcome following rt-PA: SAMURAI rt-PA Registry. Neurology 2010;75:555-61
48. de Margerie-Mellon C, Turc G, Tisserand M, et al. Can DWIASPECTS substitute for lesion volume in acute stroke? Stroke 2013; 44:3565-67