Pesticide exposure during pregnancy, like nicotine, affects the brainstem α7 nicotinic acetylcholine receptor expression, increasing the risk of sudden unexplained perinatal death

Journal of the Neurological Sciences

Volumn 348, Issue 1-2, 2015, Pages 94-100

  Lavezzi, Anna Maria ^a   Cappiello, Achille ^b   Pusiol, Teresa ^c   Corna, Melissa Felicita ^a   Termopoli, Veronica ^b   Matturri, Luigi ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF URBINO   (Italy)

^c Institute of Anatomic Pathology S Maria   (Italy)

Author keywords

Neuropathology; Nicotine; Nicotinic receptors; Pesticides; SIDS; SIUDS

Indexed keywords

BUNGAROTOXIN RECEPTOR; CIGARETTE SMOKE; NICOTINE; PESTICIDE; CHLORINATED HYDROCARBON; ORGANOPHOSPHATE;

ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; BRAIN FUNCTION; BRAIN LEVEL; BRAIN STEM; CLINICAL ARTICLE; FEMALE; FETUS; FETUS DEATH; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFANT; MATERNAL SMOKING; NEUROTOXICITY; NEWBORN; PERINATAL DEATH; PERINATAL PERIOD; PREGNANCY; PREGNANT WOMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SMOKING; SMOKING HABIT; SUDDEN INFANT DEATH SYNDROME; ADVERSE EFFECTS; DRUG EFFECTS; MALE; RURAL POPULATION; SUDDEN INFANT DEATH;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; BRAIN STEM; FEMALE; FETAL DEATH; GESTATIONAL AGE; HUMANS; HYDROCARBONS, CHLORINATED; INFANT; INFANT, NEWBORN; MALE; NICOTINE; ORGANOPHOSPHATES; PERINATAL DEATH; PESTICIDES; PREGNANCY; RURAL POPULATION; SMOKING; SUDDEN INFANT DEATH;

EID: 84920973159     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2014.11.014     Document Type: Article

References (46)

1. J. Lumley, S. Oliver, and E. Waters Interventions for promoting smoking cessation during pregnancy Cochrane Database Syst Rev 2 2000 (CD001055)
2. I.T. Agaku, B.A. King, and S.R. Dube Centers for Disease Control and Prevention (CDC). Current cigarette smoking among adults - United States, 2005-2012 MMWR Morb. Mortal. Wkly Rep. 63 2014 29 34
3. K.N. Polen, P.K. Sandhu, M.A. Honein, K.K. Green, J.M. Berkowitz, J. Pace, and S.A. Rasmussen Knowledge and attitudes of adults towards smoking in pregnancy: results from the HealthStyles© 2008 survey Matern Child Health J 2014 10.1007/s10995-014-1505-0
4. J.M. Rogers Tobacco and pregnancy Reprod Toxicol 28 2009 152 160
5. A. Muhammad, R. Mychasiuk, A. Nakahashi, S.R. Hossain, R. Gibb, and B. Kolb Prenatal nicotine exposure alters neuroanatomical organization of the developing brain Synapse 66 2012 950 954
6. J.B. Dwyer, R.S. Broide, and F.M. Leslie Nicotine and brain development Birth Defects Res C Embryo Today 84 2008 30 44
7. J.M. Lauder, and U.B. Schambra Morphogenetic roles of acetylcholine Environ Health Perspect 107 1999 65 69
8. M.R. Picciotto, M.J. Higley, and Y.S. Mineur Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior Neuron 76 2012 116 129
9. R.T. Boyd The molecular biology of neuronal nicotinic acetylcholine receptors Crit Rev Toxicol 27 1997 299 318
10. J.P. Changeux, D. Bertrand, P.J. Corringer, S. Dehaene, S. Edelstein, C. Lena, N. Le Novere, L. Marubio, M. Picciotto, and M. Zoli Brain nicotinic receptors: structure and regulation, role in learning and reinforcement Brain Res Rev 26 1998 198 216
11. R. Hurst, H. Rollema, and D. Bertrand Nicotinic acetylcholine receptors: from basic science to therapeutics Pharmacol Ther 137 2013 22 54
12. E. Hellström-Lindahl, Å. Seiger, A. Kjaeldgaard, and A. Nordberg Nicotine-induced alterations in the expression of nicotinic receptors in primary cultures from human prenatal brain Neuroscience 105 2001 527 534
13. R.S. Broide, and F.M. Leslie The alpha7 nicotinic acetylcoline receptor in neuronal plasticity Mol Neurobiol 20 1999 1 16
14. L. Falk, A. Nordberg, A. Seiger, A. Kjaeldgaard, and E. Hellström-Lindahl The alpha7 nicotinic receptors in human fetal brain and spinal cord J Neurochem 80 2002 457 465
15. T.A. Slotkin Developmental cholinotoxicants: nicotine and chlorpyrifos Environ Health Perspect 107 1999 71 80 (Review)
16. T.A. Slotkin Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates Toxicol Appl Pharmacol 198 2004 132 151
17. T.A. Slotkin, M.C. Southard, S.J. Adam, M.M. Cousins, and F.J. Seidler Alpha7 nicotinic acetylcholine receptors targeted by cholinergic developmental neurotoxicants: nicotine and chlorpyrifos Brain Res Bull 64 2004 227 235
18. J.D. Bancroft, and M. Gamble Theory and practice of histological techniques 5th ed. 2002 Churchill Livingstone 79 82
19. J. Olszewski, and D. Baxter Cytoarchitecture of the human brainstem J.A. Büttner-Ennever, A.K.E. Horn, 3rd ed. 2014 Karger, Basel
20. A.M. Lavezzi, G. Ottaviani, G.M. Ballabio, L. Rossi, and L. Matturri Preliminary study on the cytoarchitecture of the human parabrachial/Kölliker-Fuse complex with reference to sudden infant death syndrome and sudden intrauterine unexplained death Pediatr Dev Pathol 72 2004 171 179
21. A.M. Lavezzi, and L. Matturri Functional neuroanatomy of the human pre-Bötzinger complex with particular reference to sudden unexplained perinatal and infant death Neuropathology 28 2008 10 16
22. A.M. Lavezzi, D.E. Weese-Mayer, M.Y. Yu, L.J. Jennings, M.F. Corna, V. Casale, R. Oneda, and L. Matturri Developmental alterations of the respiratory human retrotrapezoid nucleus in sudden unexplained fetal and infant death Auton Neurosci 170 2012 12 19
23. R.J. Landis, and G.G. Koch The measurement of observer agreement for categorical data Biometrics 33 1977 159 174
24. A. Cappiello, G. Famiglini, P. Palma, V. Termopoli, A.M. Lavezzi, and L. Matturri Determination of selected endocrine disrupting compounds in human fetal and newborn tissues by GC-MS Anal Bioanal Chem 406 2014 2779 2788
25. L. Falk, A. Nordberg, A. Seiger, A. Kjaeldgaard, and E. Hellström-Lindahl The alpha7 nicotinic receptors in human fetal brain and spinal cord J. Neurochem. 80 2002 457 465
26. L. Role, and D.K. Berg Nicotinic receptors in the development and modulation of CNS synapses Neuron 16 1996 1077 1085
27. 3H]nicotine binding sites in human brain J Neurochem 50 1988 1243 1247
28. D.C. Perry, M.I. Davila-Garcia, C.A. Stockmeier, and K.J. Kellar Increased nicotinic receptors in brains from smokers: membrane binding and autoradiography studies J Pharmacol Exp Ther 289 1999 1545 1552
29. 3H]nicotine binding in the human brainstem Neuroscience 55 1993 1127 1138
30. A.M. Lavezzi, V. Casale, R. Oneda, D.E. Weese-Mayer, and L. Matturri Sudden infant death syndrome and sudden intrauterine unexplained death: correlation between hypoplasia of raphé nuclei and serotonin transporter gene promoter polymorphism Pediatr Res 66 2009 22 27
31. A.M. Lavezzi, and L. Matturri Hypoplasia of the parafacial/facial complex: a very frequent finding in sudden unexplained fetal death Open Neurosci J 2 2008 1 5
32. P. Atluri, M.W. Fleck, Q. Shen, S.J. Mah, D. Stadfelt, W. Barnes, S.K. Goderie, S. Temple, and A.S. Schneider Functional nicotinic acetylcholine receptor expression in stem and progenitor cells of the early embryonic mouse cerebral cortex Dev Biol 240 2001 143 156
33. T.S. Roy, J.E. Andrews, F.J. Seidler, and T.A. Slotkin Nicotine evokes cell death in embryonic rat brain during neurulation J Pharmacol Exp Ther 287 1998 1135 1144
34. S.M. Gospe Jr., J.A. Joyce, J.R. Siebert, R.M. Jack, and K.E. Pinkerton Exposure to environmental tobacco smoke during pregnancy in rats yields less effect on indices of brain cell number and size than does postnatal exposure Reprod Toxicol 27 2009 22 27
35. S.M. Gospe Jr., S.S. Zhou, and K.E. Pinkerton Effects of environmental tobacco smoke exposure in utero and/or postnatally on brain development Pediatr Res 39 1996 494 498
36. T.A. Slotkin, L. Orband-Miller, K.L. Queen, W.L. Whitmore, and F.J. Seidler Effects of prenatal nicotine exposure on biochemical development of rat brain regions: maternal drug infusions via osmotic minipumps J Pharmacol Exp Ther 240 1987 602 611
37. J.R. Duncan, T.K. Welty, S. Iyasu, and H.C. Kinney The effect of maternal smoking and drinking during pregnancy upon (3)H-nicotine receptor brainstem binding in infants dying of the sudden infant death syndrome: initial observations in a high risk population Brain Pathol 18 2008 21 31
38. 3H-nicotine receptor binding in the sudden infant death syndrome J Neuropathol Exp Neurol 57 1998 1018 1025
39. R. Machaalani, M. Say, and K.A. Waters Effects of cigarette smoke exposure on nicotinic acetylcholine receptor subunits α7 and β2 in the sudden infant death syndrome (SIDS) brainstem Toxicol Appl Pharmacol 257 2011 396 404
40. EU Council Directive 98/83/EC of 3 November 1998 on the quality of water intended for human consumption Off J Eur Communities L330 1998 32 54
41. P. Myllynen, M. Pasanen, and O. Pelkonen Human placenta: a human organ for developmental toxicology research and biomonitoring Placenta 26 2005 361 371
42. D.B. Barr, A. Bishop, and L.L. Needham Concentrations of xenobiotic chemicals in the maternal-fetal unit Reprod Toxicol 23 2007 260 266
43. J. Tan, A. Loganath, Y.S. Chong, and J.P. Obbard Exposure to persistent organic pollutants in utero and related maternal characteristics on birth outcomes: a multivariate data analysis approach Chemosphere 74 2009 428 433
44. B. Eskenazi, K. Harley, A. Bradman, E. Weltzien, N.P. Jewell, D.B. Barr, C.E. Furlong, and N.T. Holland Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population Environ Health Perspect 112 2004 1116 1124
45. S. Mary, M.S. Wolff, S. Engel, G. Berkowitz, S. Teitelbaum, J. Siskind, D.B. Barr, and J. Wetmur Prenatal pesticide and PCB exposures and birth outcomes Pediatr Res 61 2007 243 250
46. D. Qiao, F.J. Seidler, J.D. Violin, and T.A. Slotkin Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos Brain Res Dev Brain Res 147 2003 183 190