-
1
-
-
0036359548
-
Hypoxia-A key regulatory factor in tumour growth
-
Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
2
-
-
44349157832
-
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
-
Dewhirst MW, Cao Y, Moeller B. Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response. Nat Rev Cancer 2008;8:425-37.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 425-437
-
-
Dewhirst, M.W.1
Cao, Y.2
Moeller, B.3
-
3
-
-
0035925098
-
Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
-
Hockel M, Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 2001;93:266-76.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 266-276
-
-
Hockel, M.1
Vaupel, P.2
-
4
-
-
68049105076
-
Role of hypoxia in the hallmarks of human cancer
-
Ruan K, Song G, Ouyang G. Role of hypoxia in the hallmarks of human cancer. J Cell Biochem 2009;107:1053-62.
-
(2009)
J Cell Biochem
, vol.107
, pp. 1053-1062
-
-
Ruan, K.1
Song, G.2
Ouyang, G.3
-
5
-
-
77953767072
-
Hypoxia and the malignant glioma microenvironment: Regulation and implications for therapy
-
Oliver L, Olivier C, Marhuenda FB, Campone M, Vallette FM. Hypoxia and the malignant glioma microenvironment: regulation and implications for therapy. Curr Mol Pharmacol 2009;2:263-84.
-
(2009)
Curr Mol Pharmacol
, vol.2
, pp. 263-284
-
-
Oliver, L.1
Olivier, C.2
Marhuenda, F.B.3
Campone, M.4
Vallette, F.M.5
-
6
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
7
-
-
0036547417
-
Death and anti-death: Tumour resistance to apoptosis
-
Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2002;2:277-88.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 277-288
-
-
Igney, F.H.1
Krammer, P.H.2
-
8
-
-
58149296552
-
Tumor resistance to apoptosis
-
Fulda S. Tumor resistance to apoptosis. Int J Cancer 2009;124:511-5.
-
(2009)
Int J Cancer
, vol.124
, pp. 511-515
-
-
Fulda, S.1
-
9
-
-
0033082995
-
IAP family proteins-suppressors of apoptosis
-
Deveraux QL, Reed JC. IAP family proteins-suppressors of apoptosis. Genes Dev 1999;13:239-52.
-
(1999)
Genes Dev
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
10
-
-
42449152756
-
Inhibitor of apoptosis proteins and apoptosis
-
Wei Y, Fan T, Yu M. Inhibitor of apoptosis proteins and apoptosis. Acta Biochim Biophys Sin 2008;40:278-88.
-
(2008)
Acta Biochim Biophys Sin
, vol.40
, pp. 278-288
-
-
Wei, Y.1
Fan, T.2
Yu, M.3
-
11
-
-
0034597630
-
ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas
-
Vucic D, Stennicke HR, Pisabarro MT, Salvesen GS, Dixit VM. ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas. Curr Biol 2000;10:1359-66.
-
(2000)
Curr Biol
, vol.10
, pp. 1359-1366
-
-
Vucic, D.1
Stennicke, H.R.2
Pisabarro, M.T.3
Salvesen, G.S.4
Dixit, V.M.5
-
12
-
-
0034731359
-
KIAP, a novelmember of the inhibitor of apoptosis protein family
-
Lin JH, Deng G, Huang Q, Morser J. KIAP, a novelmember of the inhibitor of apoptosis protein family. Biochem Biophys Res Commun 2000;279: 820-31.
-
(2000)
Biochem Biophys Res Commun
, vol.279
, pp. 820-831
-
-
Lin, J.H.1
Deng, G.2
Huang, Q.3
Morser, J.4
-
13
-
-
0035793557
-
Livin, a novel inhibitor of apoptosis protein family member
-
Kasof GM, Gomes BC. Livin, a novel inhibitor of apoptosis protein family member. J Biol Chem 2001;276:3238-46.
-
(2001)
J Biol Chem
, vol.276
, pp. 3238-3246
-
-
Kasof, G.M.1
Gomes, B.C.2
-
14
-
-
34047100316
-
Livin/ML-IAP as a new target for cancer treatment
-
Liu B, Han M, Wen JK, Wang L. Livin/ML-IAP as a new target for cancer treatment. Cancer Lett 2007;250:168-76.
-
(2007)
Cancer Lett
, vol.250
, pp. 168-176
-
-
Liu, B.1
Han, M.2
Wen, J.K.3
Wang, L.4
-
15
-
-
33646228168
-
Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response
-
Sarkaria JN, Carlson BL, Schroeder MA, Grogan P, Brown PD, Giannini C, et al. Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response. Clin Cancer Res 2006;12:2264-71.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2264-2271
-
-
Sarkaria, J.N.1
Carlson, B.L.2
Schroeder, M.A.3
Grogan, P.4
Brown, P.D.5
Giannini, C.6
-
16
-
-
80052831432
-
NADPH oxidase subunit 4-mediated reactive oxygen species contribute to cycling hypoxia-promoted tumor progression in glioblastoma multiforme
-
Hsieh CH, Shyu WC, Chiang CY, Kuo JW, Shen WC, Liu RS. NADPH oxidase subunit 4-mediated reactive oxygen species contribute to cycling hypoxia-promoted tumor progression in glioblastoma multiforme. PLoS ONE 2011;6:e23945.
-
(2011)
PLoS ONE
, vol.6
, pp. e23945
-
-
Hsieh, C.H.1
Shyu, W.C.2
Chiang, C.Y.3
Kuo, J.W.4
Shen, W.C.5
Liu, R.S.6
-
17
-
-
84864404681
-
NADPHoxidase subunit 4mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme
-
Hsieh CH, WuCP, Lee HT, Liang JA, Yu CY, Lin YJ. NADPHoxidase subunit 4mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme. Free Radic Biol Med 2012;53:649-58.
-
(2012)
Free Radic Biol Med
, vol.53
, pp. 649-658
-
-
Hsieh, C.H.1
Wu, C.P.2
Lee, H.T.3
Liang, J.A.4
Yu, C.Y.5
Lin, Y.J.6
-
18
-
-
84866920135
-
Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1
-
Chou CW, Wang CC, WuCP, Lin YJ, Lee YC, Cheng YW, et al. Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1. Neuro-oncology 2012;14: 1227-38.
-
(2012)
Neuro-oncology
, vol.14
, pp. 1227-1238
-
-
Chou, C.W.1
Wang, C.C.2
Wu, C.P.3
Lin, Y.J.4
Lee, Y.C.5
Cheng, Y.W.6
-
19
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987-96.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
-
20
-
-
77952562129
-
Isolation of peptides blocking the function of anti-apoptotic Livin protein
-
Crnkovic-Mertens I, Bulkescher J, Mensger C, Hoppe-Seyler F, Hoppe-Seyler K. Isolation of peptides blocking the function of anti-apoptotic Livin protein. Cell Mol Life Sci 2010;67:1895-905.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 1895-1905
-
-
Crnkovic-Mertens, I.1
Bulkescher, J.2
Mensger, C.3
Hoppe-Seyler, F.4
Hoppe-Seyler, K.5
-
21
-
-
84865523103
-
Imaging the impact of Nox4 in cycling hypoxia-mediated U87 glioblastoma invasion and infiltration
-
Hsieh CH, Chang HT, Shen WC, Shyu WC, Liu RS. Imaging the impact of Nox4 in cycling hypoxia-mediated U87 glioblastoma invasion and infiltration. Mol Imaging Biol 2012;14:489-99.
-
(2012)
Mol Imaging Biol
, vol.14
, pp. 489-499
-
-
Hsieh, C.H.1
Chang, H.T.2
Shen, W.C.3
Shyu, W.C.4
Liu, R.S.5
-
22
-
-
65649115060
-
Hypoxia helps glioma to fight therapy
-
Amberger-Murphy V. Hypoxia helps glioma to fight therapy. Curr Cancer Drug Targets 2009;9:381-90.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 381-390
-
-
Amberger-Murphy, V.1
-
23
-
-
0032917709
-
Expression and biological activity of X-linked inhibitor of apoptosis (XIAP) in human malignant glioma
-
Wagenknecht B, Glaser T, Naumann U, Kugler S, Isenmann S, Bahr M, et al. Expression and biological activity of X-linked inhibitor of apoptosis (XIAP) in human malignant glioma. Cell Death Differ 1999; 6:370-6.
-
(1999)
Cell Death Differ
, vol.6
, pp. 370-376
-
-
Wagenknecht, B.1
Glaser, T.2
Naumann, U.3
Kugler, S.4
Isenmann, S.5
Bahr, M.6
-
24
-
-
0033517839
-
A human IAPfamily gene, apollon, expressed in human brain cancer cells
-
Chen Z, Naito M, Hori S, Mashima T, Yamori T, Tsuruo T. A human IAPfamily gene, apollon, expressed in human brain cancer cells. Biochem Biophys Res Commun 1999;264:847-54.
-
(1999)
Biochem Biophys Res Commun
, vol.264
, pp. 847-854
-
-
Chen, Z.1
Naito, M.2
Hori, S.3
Mashima, T.4
Yamori, T.5
Tsuruo, T.6
-
25
-
-
0037083317
-
Quantitatively determined survivin expression levels are of prognostic value in human gliomas
-
Chakravarti A, Noll E, Black PM, Finkelstein DF, Finkelstein DM, Dyson NJ, et al. Quantitatively determined survivin expression levels are of prognostic value in human gliomas. J Clin Oncol 2002;20: 1063-8.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1063-1068
-
-
Chakravarti, A.1
Noll, E.2
Black, P.M.3
Finkelstein, D.F.4
Finkelstein, D.M.5
Dyson, N.J.6
-
26
-
-
46549084099
-
Comparison between cells and cancer stem-like cells isolated from glioblastomaand astrocytoma on expression of anti-apoptotic and multidrug resistance-associated protein genes
-
Jin F, Zhao L, ZhaoHY, Guo SG, Feng J, Jiang XB, et al. Comparison between cells and cancer stem-like cells isolated from glioblastomaand astrocytoma on expression of anti-apoptotic and multidrug resistance-associated protein genes. Neuroscience 2008;154:541-50.
-
(2008)
Neuroscience
, vol.154
, pp. 541-550
-
-
Jin, F.1
Zhao, L.2
Zhao, H.Y.3
Guo, S.G.4
Feng, J.5
Jiang, X.B.6
-
27
-
-
77953125390
-
Influence of Etoposide on anti-apoptotic and multidrug resistance-associated protein genes in CD133 positive U251 glioblastoma stem-like cells
-
Jin F, Zhao L, Guo YJ, Zhao WJ, Zhang H, Wang HT, et al. Influence of Etoposide on anti-apoptotic and multidrug resistance-associated protein genes in CD133 positive U251 glioblastoma stem-like cells. Brain Res 2010;1336:103-11.
-
(2010)
Brain Res
, vol.1336
, pp. 103-111
-
-
Jin, F.1
Zhao, L.2
Guo, Y.J.3
Zhao, W.J.4
Zhang, H.5
Wang, H.T.6
-
28
-
-
84857434415
-
Research progress on Livin protein: An inhibitor of apoptosis
-
Yan B. Research progress on Livin protein: an inhibitor of apoptosis. Mol Cell Biochem 2011;357:39-45.
-
(2011)
Mol Cell Biochem
, vol.357
, pp. 39-45
-
-
Yan, B.1
-
29
-
-
0035378480
-
Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms
-
Dong Z, Venkatachalam MA, Wang J, Patel Y, Saikumar P, Semenza GL, et al. Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms. J Biol Chem 2001;276: 18702-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 18702-18709
-
-
Dong, Z.1
Venkatachalam, M.A.2
Wang, J.3
Patel, Y.4
Saikumar, P.5
Semenza, G.L.6
-
30
-
-
63849178889
-
Effect of hypoxia-inducible factor-1alpha on transcription of survivin in non-small cell lung cancer
-
Chen YQ, Zhao CL, Li W. Effect of hypoxia-inducible factor-1alpha on transcription of survivin in non-small cell lung cancer. J Exp Clin Cancer Res 2009;28:29.
-
(2009)
J Exp Clin Cancer Res
, vol.28
, pp. 29
-
-
Chen, Y.Q.1
Zhao, C.L.2
Li, W.3
-
31
-
-
84876321398
-
Livin promotes progression of breast cancer through induction of epithelial-mesenchymal transition and activation of AKT signaling
-
Li F, Yin X, Luo X, Li HY, Su X, Wang XY, et al. Livin promotes progression of breast cancer through induction of epithelial-mesenchymal transition and activation of AKT signaling. Cell Signal 2013;25: 1413-22.
-
(2013)
Cell Signal
, vol.25
, pp. 1413-1422
-
-
Li, F.1
Yin, X.2
Luo, X.3
Li, H.Y.4
Su, X.5
Wang, X.Y.6
-
32
-
-
0344873763
-
Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene
-
Crnkovic-Mertens I, Hoppe-Seyler F, Butz K. Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene. Oncogene 2003;22:8330-6.
-
(2003)
Oncogene
, vol.22
, pp. 8330-8336
-
-
Crnkovic-Mertens, I.1
Hoppe-Seyler, F.2
Butz, K.3
-
33
-
-
84861690493
-
SiRNA directed against Livin inhibits tumor growth and induces apoptosis in human glioma cells
-
Yuan B, Ran B, Wang S, Liu Z, Zheng Z, Chen H. siRNA directed against Livin inhibits tumor growth and induces apoptosis in human glioma cells. J Neurooncol 2012;107:81-7.
-
(2012)
J Neurooncol
, vol.107
, pp. 81-87
-
-
Yuan, B.1
Ran, B.2
Wang, S.3
Liu, Z.4
Zheng, Z.5
Chen, H.6
-
34
-
-
78651314500
-
Potential clinical applications of siRNA technique: Benefits and limitations
-
Chen SH, Zhaori G. Potential clinical applications of siRNA technique: benefits and limitations. Eur J Clin Invest 2011;41:221-32.
-
(2011)
Eur J Clin Invest
, vol.41
, pp. 221-232
-
-
Chen, S.H.1
Zhaori, G.2
-
35
-
-
84884254106
-
IAP proteins as targets for drug development in oncology
-
Dubrez L, Berthelet J, Glorian V. IAP proteins as targets for drug development in oncology. Onco Targets Ther 2013;9:1285-304.
-
(2013)
Onco Targets Ther
, vol.9
, pp. 1285-1304
-
-
Dubrez, L.1
Berthelet, J.2
Glorian, V.3
-
36
-
-
79960224920
-
Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2
-
Darding M, Feltham R, Tenev T, Bianchi K, Benetatos C, Silke J, et al. Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2. Cell Death Differ 2011;18:1376-86.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1376-1386
-
-
Darding, M.1
Feltham, R.2
Tenev, T.3
Bianchi, K.4
Benetatos, C.5
Silke, J.6
|