Identification of metabolites of gardenin A in rats by combination of high-performance liquid chromatography with linear ion trap-Orbitrap mass spectrometer based on multiple data processing techniques

Biomedical Chromatography

Volumn 29, Issue 3, 2015, Pages 379-387

  Zhang, Jiayu ^a   Wang, Fang ^a   Cai, Wei ^a   Zhang, Qian ^a   Liu, Ying ^a   Li, Yun ^a   Liu, Rongrong ^a   Cao, Guangshang ^b  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b AFFILIATED HOSPITAL OF SHANDONG UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Gardenin A; HPLC ESI MS MS; Hydroxylated polymethoxyflavonoids (OH PMFs); Metabolite

Indexed keywords

ALKYLATION; BIOMOLECULES; DATA ACQUISITION; DATA HANDLING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; ION CHROMATOGRAPHY; IONS; MASS SPECTROMETERS; METABOLISM; SULFUR COMPOUNDS;

DATA PROCESSING TECHNIQUES; GARDENIN A; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HPLC-ESI-MS/MS; HPLC/ESI-MS/MS; HYDROXYLATED POLYMETHOXYFLAVONOID (ONE OF THE LESS ABUNDANT HYDROXYLATED POLYMETHOXYFLAVONOID); IN-VIVO; LINEAR ION TRAP; MULTIPLE DATA; ORBITRAP;

METABOLITES;

DRUG METABOLITE; FLAVONOID; GARDENIN A; UNCLASSIFIED DRUG; FLAVONE DERIVATIVE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DATA PROCESSING; DEMETHYLATION; DRUG CONJUGATION; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG TRANSFORMATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETER; MASS SPECTROMETRY; METHYLATION; NONHUMAN; RAT; ANIMAL; BIOTRANSFORMATION; CHEMISTRY; DEVICES; ELECTROSPRAY MASS SPECTROMETRY; INFORMATION PROCESSING; METABOLISM; MURRAYA; ORAL DRUG ADMINISTRATION; PROCEDURES; SPRAGUE DAWLEY RAT; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION;

RATTUS;

ADMINISTRATION, ORAL; ANIMALS; AUTOMATIC DATA PROCESSING; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLAVONES; MALE; MURRAYA; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION;

EID: 84920945097     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.3287     Document Type: Article

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