Research on the efficacy of Celastrus Orbiculatus in suppressing TGF-β1-induced epithelial-mesenchymal transition by inhibiting HSP27 and TNF-α-induced NF-κB/Snail signaling pathway in human gastric adenocarcinoma

BMC Complementary and Alternative Medicine

Volumn 14, Issue 1, 2014, Pages

  Zhu, Yaodong ^a,b   Liu, Yanqing ^a,b   Qian, Yayun ^a,b   Dai, Xiaojun ^a,b   Yang, Ling ^a,b   Chen, Jue ^a,b   Guo, Shiyu ^c   Hisamitsu, Tadashi ^c  

^a YANGZHOU UNIVERSITY   (China)

^b Jiangsu Key Laboratory of Integrated Traditional Chinese   (China)

^c SHOWA UNIVERSITY   (Japan)

Author keywords

Celastrus orbiculatus; Epithelial mesenchymal transition; Gastric cancer; HSP27; NF B

Indexed keywords

ANTINEOPLASTIC AGENT; CAPECITABINE; CELASTRUS ORBICULATUS EXTRACT; CELL PROTEIN; HEAT SHOCK PROTEIN 27; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NERVE CELL ADHESION MOLECULE; PLANT EXTRACT; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; CADHERIN; HERBACEOUS AGENT; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CANCER MODEL; CELASTRUS; CELASTRUS ORBICULATUS; CELL INVASION; CELL MIGRATION; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSTASIS; DOWN REGULATION; DRUG EFFICACY; DRUG ISOLATION; DRUG MEGADOSE; DRUG TARGETING; EPITHELIAL MESENCHYMAL TRANSITION; GASTRIC CANCER CELL LINE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; PERITONEUM CANCER; PLASMID; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; RETROVIRIDAE; SGC 7901 CELL; SIGNAL TRANSDUCTION; STOMACH ADENOCARCINOMA; TRANSCRIPTION INITIATION; TUMOR XENOGRAFT; VIRUS RECOMBINANT; ADENOCARCINOMA; ANIMAL; CELL MOTION; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NUDE MOUSE; PATHOPHYSIOLOGY; STOMACH NEOPLASMS; TUMOR CELL LINE;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CADHERINS; CELASTRUS; CELL LINE, TUMOR; CELL MOVEMENT; DRUGS, CHINESE HERBAL; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HSP27 HEAT-SHOCK PROTEINS; HUMANS; MALE; MICE; MICE, NUDE; NF-KAPPA B; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84920850760     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-433     Document Type: Article

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