Tuning riboswitch-mediated gene regulation by rational control of aptamer ligand binding properties

Angewandte Chemie - International Edition

Volumn 54, Issue 3, 2015, Pages 905-909

  Rode, Ambadas B ^a   Endoh, Tamaki ^a   Sugimoto, Naoki ^a  

^a KONAN UNIVERSITY   (Japan)

Author keywords

Aptamers; Flavin mononucleotides; Gene regulation; Kinetics; Riboswitches

Indexed keywords

BINDING ENERGY; DISSOCIATION; ENZYME KINETICS; GENES; KINETICS; LIGANDS; RATIONAL FUNCTIONS;

APTAMERS; CONTROL OF GENE EXPRESSION; DISSOCIATION CONSTANT; EFFECTIVE CONCENTRATION; FLAVIN MONO NUCLEOTIDES (FMN); FLAVIN MONONUCLEOTIDES; LIGAND BINDING PROPERTIES; RIBOSWITCHES;

GENE EXPRESSION;

APTAMER; FLAVINE MONONUCLEOTIDE; LIGAND; RIBOSWITCH;

BACILLUS SUBTILIS; CHEMISTRY; CONFORMATION; GENE EXPRESSION REGULATION; KINETICS; METABOLISM; PSEUDOMONAS FLUORESCENS; RIBOSWITCH;

APTAMERS, NUCLEOTIDE; BACILLUS SUBTILIS; FLAVIN MONONUCLEOTIDE; GENE EXPRESSION REGULATION, BACTERIAL; KINETICS; LIGANDS; NUCLEIC ACID CONFORMATION; PSEUDOMONAS FLUORESCENS; RIBOSWITCH;

EID: 84920816915     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201407385     Document Type: Article

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