Transfusion of fresh-frozen plasma in critically ill patients with a coagulopathy before invasive procedures: A randomized clinical trial (CME)

Transfusion

Volumn 55, Issue 1, 2015, Pages 26-35

  Müller, Marcella C ^a   Arbous, M Sesmu ^b   Spoelstra De Man, Angelique M ^c   Vink, Roel ^d   Karakus, Atilla ^e   Straat, Marleen ^a   Binnekade, Jan M ^a   De Jonge, Evert ^b   Vroom, Margreeth B ^a   Juffermans, Nicole P ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d Department of Intensive Care Medicine Tergooiziekenhuizen ^*  (Netherlands)

^e DEPARTMENT OF SURGERY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

FRESH FROZEN PLASMA;

ABSCESS DRAINAGE; ADULT; AGED; ANTICOAGULATION; ARTICLE; ARTIFICIAL VENTILATION; BLEEDING; BLOOD CLOTTING DISORDER; CENTRAL VENOUS CATHETERIZATION; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DISSEMINATED INTRAVASCULAR CLOTTING; FEMALE; HEART FAILURE; HUMAN; INTENSIVE CARE UNIT; INTERNATIONAL NORMALIZED RATIO; INVASIVE PROCEDURE; LENGTH OF STAY; LIVER DISEASE; LUNG DISEASE; LUNG INJURY; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; OPEN STUDY; PARTIAL THROMBOPLASTIN TIME; PLASMA TRANSFUSION; PROPHYLAXIS; PROTHROMBIN TIME; RANDOMIZED CONTROLLED TRIAL; SEPSIS; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; TRACHEOSTOMY; VENTILATOR ASSOCIATED PNEUMONIA; ABSCESS; ACUTE LUNG INJURY; ADVERSE EFFECTS; CHEST TUBE; CLINICAL TRIAL; COMPARATIVE STUDY; CRITICAL ILLNESS; DRAINAGE; HEMORRHAGE; HEMORRHAGIC DISORDERS; MIDDLE AGED; PLASMA; PREOPERATIVE CARE; PROCEDURES; PUNCTURE; SEVERITY OF ILLNESS INDEX; SINGLE BLIND PROCEDURE; STATISTICS AND NUMERICAL DATA; TREATMENT OUTCOME; UNNECESSARY PROCEDURE;

ABSCESS; ACUTE LUNG INJURY; AGED; CATHETERIZATION, CENTRAL VENOUS; CHEST TUBES; CRITICAL ILLNESS; DRAINAGE; FEMALE; HEMORRHAGE; HEMORRHAGIC DISORDERS; HUMANS; INTENSIVE CARE UNITS; INTERNATIONAL NORMALIZED RATIO; LENGTH OF STAY; MALE; MIDDLE AGED; PLASMA; PREOPERATIVE CARE; PUNCTURES; RESPIRATION, ARTIFICIAL; SEVERITY OF ILLNESS INDEX; SINGLE-BLIND METHOD; TRACHEOSTOMY; TREATMENT OUTCOME; UNNECESSARY PROCEDURES;

EID: 84920806825     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/trf.12750     Document Type: Article

References (49)

1. O'Shaughnessy DF, Atterbury C, Bolton MP, et al. Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant. Br J Haematol 2004; 126: 11-28.
2. De Backer D, Vandekerckhove B, Stanworth S, et al. Guidelines for the use of fresh frozen plasma. Acta Clin Belg 2008; 63: 381-390.
3. Wallis JP, Dzik S,. Is fresh frozen plasma overtransfused in the United States? Transfusion 2004; 44: 1674-1675.
4. Serious Hazards of Transfusion Steering Committee. Serious hazards of transfusion: annual report. 2012. [cited 2013 Nov 5]. Available from: http://www.shotuk.org/
5. Walsh TS, Stanworth SJ, Prescott RJ, et al. Prevalence, management, and outcomes of critically ill patients with prothrombin time prolongation in United Kingdom intensive care units. Crit Care Med 2010; 38: 1939-1946.
6. Lauzier F, Cook D, Griffith L, et al. Fresh frozen plasma transfusion in critically ill patients. Crit Care Med 2007; 35: 1655-1659.
7. Stanworth SJ, Walsh TS, Prescott RJ, et al. A national study of plasma use in critical care: clinical indications, dose and effect on prothrombin time. Crit Care 2011; 15: R108.
8. Stanworth SJ, Grant-Casey J, Lowe D, et al. The use of fresh-frozen plasma in England: high levels of inappropriate use in adults and children. Transfusion 2011; 51: 62-70.
9. Tinmouth A, Thompson T, Arnold DM, et al. Utilization of frozen plasma in Ontario: a provincewide audit reveals a high rate of inappropriate transfusions. Transfusion 2013; 53: 2222-2229.
10. Abdel-Wahab OI, Healy B, Dzik WH,. Effect of fresh-frozen plasma transfusion on prothrombin time and bleeding in patients with mild coagulation abnormalities. Transfusion 2006; 46: 1279-1285.
11. Watson DM, Stanworth SJ, Wyncoll D, et al. A national clinical scenario-based survey of clinicians' attitudes towards fresh frozen plasma transfusion for critically ill patients. Transfus Med 2011; 21: 124-129.
12. Chowdhury P, Saayman AG, Paulus U, et al. Efficacy of standard dose and 30 ml/kg fresh frozen plasma in correcting laboratory parameters of haemostasis in critically ill patients. Br J Haematol 2004; 125: 69-73.
13. Segal JB, Dzik WH,. Paucity of studies to support that abnormal coagulation test results predict bleeding in the setting of invasive procedures: an evidence-based review. Transfusion 2005; 45: 1413-1425.
14. Hibbert RM, Atwell TD, Lekah A, et al. Safety of ultrasound-guided thoracentesis in patients with abnormal preprocedural coagulation parameters. Chest 2013; 144: 456-463.
15. Rosseland LA, Laake JH, Stubhaug A,. Percutaneous dilatational tracheotomy in intensive care unit patients with increased bleeding risk or obesity. A prospective analysis of 1000 procedures. Acta Anaesthesiol Scand 2011; 55: 835-841.
16. Carino GP, Tsapenko AV, Sweeney JD,. Central line placement in patients with and without prophylactic plasma. J Crit Care 2012; 27: 529 e9-13.
17. Stanworth SJ, Brunskill SJ, Hyde CJ, et al. Is fresh frozen plasma clinically effective? A systematic review of randomized controlled trials. Br J Haematol 2004; 126: 139-152.
18. Yang L, Stanworth S, Hopewell S, et al. Is fresh-frozen plasma clinically effective? An update of a systematic review of randomized controlled trials. Transfusion 2012; 52: 1673-1686.
19. Dara SI, Rana R, Afessa B, et al. Fresh frozen plasma transfusion in critically ill medical patients with coagulopathy. Crit Care Med 2005; 33: 2667-2671.
20. Vlaar AP, Binnekade JM, Prins D, et al. Risk factors and outcome of transfusion-related acute lung injury in the critically ill: a nested case-control study. Crit Care Med 2010; 38: 771-778.
21. Sarani B, Dunkman WJ, Dean L, et al. Transfusion of fresh frozen plasma in critically ill surgical patients is associated with an increased risk of infection. Crit Care Med 2008; 36: 1114-1118.
22. Westbrook A, Pettila V, Nichol A, et al. Transfusion practice and guidelines in Australian and New Zealand intensive care units. Intensive Care Med 2010; 36: 1138-1146.
23. Reiter N, Wesche N, Perner A,. The majority of patients in septic shock are transfused with fresh-frozen plasma. Dan Med J 2013; 60: A4606.
24. Muller MC, de Jonge E, Arbous MS, et al. Transfusion of fresh frozen plasma in non-bleeding ICU patients-TOPIC trial: study protocol for a randomized controlled trial. Trials 2011; 12: 266.
25. Arnold DM, Donahoe L, Clarke FJ, et al. Bleeding during critical illness: a prospective cohort study using a new measurement tool. Clin Invest Med 2007; 30: E93-102.
26. Murray JF, Matthay MA, Luce JM, et al. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 1988; 138: 720-723.
27. Dunnett CW, Gent M,. Significance testing to establish equivalence between treatments, with special reference to data in the form of 2X2 tables. Biometrics 1977; 33: 593-602.
28. Holland LL, Brooks JP,. Toward rational fresh frozen plasma transfusion: the effect of plasma transfusion on coagulation test results. Am J Clin Pathol 2006; 126: 133-139.
29. Mumtaz H, Williams V, Hauer-Jensen M, et al. Central venous catheter placement in patients with disorders of hemostasis. Am J Surg 2000; 180: 503-505.
30. Fisher NC, Mutimer DJ,. Central venous cannulation in patients with liver disease and coagulopathy-a prospective audit. Intensive Care Med 1999; 25: 481-485.
31. Goldfarb G, Lebrec D,. Percutaneous cannulation of the internal jugular vein in patients with coagulopathies: an experience based on 1,000 attempts. Anesthesiology 1982; 56: 321-323.
32. Doerfler ME, Kaufman B, Goldenberg AS,. Central venous catheter placement in patients with disorders of hemostasis. Chest 1996; 110: 185-188.
33. Foster PF, Moore LR, Sankary HN, et al. Central venous catheterization in patients with coagulopathy. Arch Surg 1992; 127: 273-275.
34. McVay PA, Toy PT,. Lack of increased bleeding after paracentesis and thoracentesis in patients with mild coagulation abnormalities. Transfusion 1991; 31: 164-171.
35. Hansson L, Hedner T, Dahlof B,. Prospective randomized open blinded end-point (PROBE) study. A novel design for intervention trials. Prospective Randomized Open Blinded End-Point. Blood Press 1992; 1: 113-119.
36. Smith DH, Neutel JM, Lacourciere Y, et al. Prospective, randomized, open-label, blinded-endpoint (PROBE) designed trials yield the same results as double-blind, placebo-controlled trials with respect to ABPM measurements. J Hypertens 2003; 21: 1291-1298.
37. Miller AB, Hoogstraten B, Staquet M, et al. Reporting results of cancer treatment. Cancer 1981; 47: 207-214.
38. Tinmouth A, Chatelain E, Fergusson D, et al. A randomized controlled trial of high and standard dose fresh frozen plasma transfusions in critically ill patients. Transfusion 2008; 48: 26A-27.
39. Holland LL, Foster TM, Marlar RA, et al. Fresh frozen plasma is ineffective for correcting minimally elevated international normalized ratios. Transfusion 2005; 45: 1234-1235.
40. Hall DP, Lone NI, Watson DM, et al. Factors associated with prophylactic plasma transfusion before vascular catheterization in non-bleeding critically ill adults with prolonged prothrombin time: a case-control study. Br J Anaesth 2012; 109: 919-927.
41. Vlaar AP, in der Maur AL, Binnekade JM, et al. A survey of physicians' reasons to transfuse plasma and platelets in the critically ill: a prospective single-centre cohort study. Transfus Med 2009; 19: 207-212.
42. Khan H, Belsher J, Yilmaz M, et al. Fresh-frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients. Chest 2007; 131: 1308-1314.
43. Gajic O, Rana R, Winters JL, et al. Transfusion-related acute lung injury in the critically ill: prospective nested case-control study. Am J Respir Crit Care Med 2007; 176: 886-891.
44. Wright SE, Snowden CP, Athey SC, et al. Acute lung injury after ruptured abdominal aortic aneurysm repair: the effect of excluding donations from females from the production of fresh frozen plasma. Crit Care Med 2008; 36: 1796-1802.
45. Rana R, Fernandez-Perez ER, Khan SA, et al. Transfusion-related acute lung injury and pulmonary edema in critically ill patients: a retrospective study. Transfusion 2006; 46: 1478-1483.
46. Gajic O, Rana R, Mendez JL, et al. Acute lung injury after blood transfusion in mechanically ventilated patients. Transfusion 2004; 44: 1468-1474.
47. Bochicchio GV, Napolitano L, Joshi M, et al. Blood product transfusion and ventilator-associated pneumonia in trauma patients. Surg Infect 2008; 9: 415-422.
48. Vamvakas EC,. Pneumonia as a complication of blood product transfusion in the critically ill: transfusion-related immunomodulation (TRIM). Crit Care Med 2006; 34: S151-159.
49. Vamvakas EC, Carven JH,. Exposure to allogeneic plasma and risk of postoperative pneumonia and/or wound infection in coronary artery bypass graft surgery. Transfusion 2002; 42: 107-113.