Blood product transfusion and ventilator-associated pneumonia in trauma patients

Surgical Infections

Volumn 9, Issue 4, 2008, Pages 415-422

  Bochicchio, Grant V ^a,b   Napolitano, Lena ^a   Joshi, Manjari ^a   Bochicchio, Kelly ^a   Shih, Diane ^a   Meyer, Walter ^a   Scalea, Thomas M ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b R ADAMS COWLEY SHOCK TRAUMA CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRESH FROZEN PLASMA;

ADULT; ARTICLE; ARTIFICIAL VENTILATION; BLOOD TRANSFUSION; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; FEMALE; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; LOGISTIC REGRESSION ANALYSIS; MALE; PRIORITY JOURNAL; RISK FACTOR; UNIVARIATE ANALYSIS; VENTILATOR ASSOCIATED PNEUMONIA;

ADULT; BLOOD COMPONENT TRANSFUSION; CRITICAL ILLNESS; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED; RISK FACTORS; TRAUMA CENTERS; VENTILATORS, MECHANICAL; WOUNDS AND INJURIES;

EID: 50849116390     PISSN: 10962964     EISSN: None     Source Type: Journal    
DOI: 10.1089/sur.2006.069     Document Type: Article

References (36)

1. Rodriguez G, Gibbons K, Bitzer L, et al. Pneumonia: Incidence, risk factors, and outcome in injured patients. J Trauma 1991;31:3:907-914.
2. Brown D, Hungness E, Campbell R. Ventilator-associated pneumonia in the surgical intensive care unit. J Trauma 2001;51:1207-1216.
3. Bochicchio G, Joshi M, Knorr K, et al. Impact of community acquired infection (CA) on acquisition of nosocomial infection, length of stay, and mortality in blunt trauma patients. Surg Infect 2002;3:1-10.
4. Bochicchio G, Joshi M, Bochicchio K, et al. A time dependent diagnosis of pneumonia. J Trauma 2004;56:296-303.
5. From www.cdc.gov/ncidod/hip/NNIS/members/2001NNIS_report.pdf
6. National Nosocomial Infections Surveillance (NNIS) System Report. Data summary from January 1992 through June 2004; issued October 2004. Am J Infect Control 2004;32:470-485.
7. Gannon CJ, Pasquale M, Tracy JK, et al. Male gender is associated with increased risk for postinjury pneumonia. Shock 2004;21:410-414.
8. Fagon JY, Chastre J, Hance AJ et al. Nosocomial pneumonia in ventilated patients. Am J Med 1993;94:281-288.
9. Craven DE, Kunches LM, Lichtenberg DA, et al. Nosocomial pneumonia and fatality in medical and surgical intensive care patients. Arch Intern Med 1988;148:1161-1168.
10. Leu HS, Kaiser DL, Mori M, et al. Hospital-acquired pneumonia: Attributable mortality and morbidity. Am J Epidemiol 1989;129:1258-1267.
11. Napolitano LM. Hospital-acquired and ventilator-associated pneumonia: What's new in diagnosis and treatment? Am J Surg 2003;186(5A):4S-14S.
12. Genuit T, Bochicchio G, Napolitano LM, et al. Prophylactic chlorhexidine oral rinse decreases ventilator-associated pneumonia in surgical ICU patients. Surg Infect 2001;2:5-18.
13. Taylor RW, Manganaro L, O'Brien J, et al. Impact of allogeneic packed red blood cell transfusion on nosocomial infection rates in the critically ill patient. Crit Care Med 2002;30:2249-2254.
14. Hughes MG, Evans HL, Lightfoot L, et al. Does prior transfusion worsen outcomes from infection in surgical patients? Surg Infect 2003;4:35-43.
15. Shorr A, Duh MS, Kelly KM, Kollef MH; CRIT Study Group. Red blood cell transfusion and ventilator-associated pneumonia: A potential link? Crit Care Med 2004;32:666-674.
16. Cook DJ, Walter SD, Cook RJ, et al. Incidence and risk factors for ventilator-associated pneumonia in critically ill patients. Ann Intern Med 1998;129:433-440.
17. Magnotti LJ, Croce MA, Fabian TC. Is ventilator-associated pneumonia in trauma patients an epiphenomenon or a cause of death? Surg Infect 2004;5:237-242.
18. Osborn TM, Tracy JK, Dunne JR, et al. Epidemiology of sepsis in patients with traumatic injury. Crit Care Med 2004;32:2234-2240.
19. Dunne JR, Malone DL, Tracy JK, Napolitano LM. Allogeneic blood transfusion in the first 24 hours after trauma is associated with increased systemic inflammatory response syndrome (SIRS) and death. Surg Infect 2004;5:395-404.
20. Malone DL, Dunne J, Tracy JK, et al. Blood transfusion, independent of shock severity, is associated with worse outcome in trauma. J Trauma 2003;54:898-905.
21. Robinson WP, Ahn J, Stiffler A, et al. Blood transfusion is an independent predictor of increased mortality in nonoperatively managed blunt hepatic and splenic injuries. J Trauma 2005;58:437-444.
22. Hill GE, Frawley WH, Griffith KE, et al. Allogeneic blood transfusion increases the risk of postoperative bacterial infection: A meta-analysis. J Trauma 2003;54:908-914.
23. Moore FA, Moore EE, Sauaia A. Blood transfusion: An independent risk factor for postinjury multiple organ failure. Arch Surg 1997;132:620-624.
24. Claridge JA, Sawyer RG, Schulman AM, et al. Blood transfusions correlate with infections in trauma patients in a dose-dependent manner. Am Surg 2002;68:566-572.
25. Rosemurgy AS, Hart MB, Murphy CG, et al. Infection after injury: Association with blood transfusion. Am Surg 1992;58:104-107.
26. Offner PJ, More EE, Biffl WL, et al. Increased rate of infection associated with transfusion of old blood after severe injury. Arch Surg 2002;137:711-716.
27. Papia G, McLellan BA, El-Helou P, et al. Infection in hospitalized trauma patients: Incidence, risk factors and complications. J Trauma 1999;47:923-927.
28. Shapiro MJ, Gettinger A, Corwin HL, et al. Anemia and blood transfusion in trauma patients admitted to the intensive care unit. J Trauma 2003;55:269-273.
29. Jeschke MG, Chinkes DL, Finnerty CC, et al. Blood transfusions are associated with increased risk for development of sepsis in severely burned pediatric patients. Crit Care Med 2007;35:579-583.
30. Falagas ME, Rosmarakis ES, Rellos K, et al. Microbiologically documented infections after coronary artery bypass surgery without cardiopulmonary bypass. J Thorac Cardiovasc Surg 2006;132:481-490.
31. Sreeram GM, Welsby IJ, Sharma AD, et al. Infectious complications after cardiac surgery: Lack of association with fresh frozen plasma or platelet transfusion. J Cardiothorac Vasc Anesth 2005;19:430-434.
32. Available at http://www.ihi.org/IHI/Topics/CriticalCare/IntensiveCare/ Changes/ImplementtheVentilatorBundle. htm
33. Shorr AF, Sherner JH, Jackson WL, Kollef MH. Invasive approaches to the diagnosis of ventilator-associated pneumonia: A meta-analysis. Crit Care Med 2005;33:46-53.
34. Canadian Critical Care Trials Group. A randomized trial of diagnostic techniques for ventilator-associated pneumonia. N Engl J Med 2006;355:2619-2630.
35. Croce MA, Tolley EA, Fabian TC. Transfusions result in pulmonary morbidity and death following moderate degree of injury [abstract]. J Trauma 2004;57:437.
36. McIntyre L, Hebert PC, Wells G, et al; Canadian Critical Care Trials Group. Is a restrictive transfusion strategy safe for resuscitated and critically ill trauma patients? J Trauma 2004;57:563-568.