TNF-alpha-308G>A polymorphism and the risk of familial CAD in a Pakistani population

Human Immunology

Volumn 76, Issue 1, 2015, Pages 13-18

  Hussain, Sabir ^a   Iqbal, Tahir ^b   Javed, Qamar ^c  

^a Department of Biosciences COMSATS Institute of Information Technology ^*  (Pakistan)

^b SHIFA INTERNATIONAL HOSPITAL   (Pakistan)

^c QUAID I AZAM UNIVERSITY   (Pakistan)

Author keywords

Association; Familial CAD; Polymorphism; TDT; TNF alpha

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ALLELE; ARTICLE; CASE CONTROL STUDY; CHEMICAL ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY RISK; DISEASE TRANSMISSION; ENZYME LINKED IMMUNOSORBENT ASSAY; FAMILIAL DISEASE; FAMILY STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HERITABILITY; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PAKISTANI; PARENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; PROTEIN BLOOD LEVEL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; SPECTROPHOTOMETRY; BLOOD; GENE EXPRESSION; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PAKISTAN; PATHOLOGY; PEDIGREE; RISK;

ADULT; ALLELES; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; ODDS RATIO; PAKISTAN; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RISK; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84920778589     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2014.12.010     Document Type: Article

References (42)

1. Roberts R., Stewart A.F. The genetics of coronary artery disease. Curr Opin Cardiol 2012, 27(3):221-227.
2. Mayer B., Erdmann J., Schunkert H. Genetics and heritability of coronary artery disease and myocardial infarction. Clin Res Cardiol 2007, 96:1-7.
3. Kazeem G.R., Farrall M. Integrating case-control and TDT studies. Ann Hum Genet 2005, 69(Pt3):329-335.
4. Hussain S., Bibi S., Javed Q. Heritability of genetic variants of resistin gene in patients with coronary artery disease: a family-based study. Clin Biochem 2011, 44:618-622.
5. Di Somma C., Charron D., Deichmann K., Buono C., Ruffilli A. Atopic asthma and TNF-308 alleles: linkage disequilibrium and association analyses. Hum Immunol 2003, 64(3):359-365.
6. Spielman R.S., McGinnis R.E., Ewens W.J. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 1993, 52:506-516.
7. Herrmann S.M., Ricard S., Nicaud V., Mallet C., Arveiler D., Evans A., et al. Polymorphisms of the tumour necrosis factor-alpha gene, coronary heart disease and obesity. Eur J Clin Invest 1998, 28:59-66.
8. Mira J.P., Cariou A., Grall F., Delclaux C., Losser M.R., Heshmati F., et al. Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study. JAMA 1999, 282:561-568.
9. Hajeer A.H., Hutchinson I.V. TNF-alpha gene polymorphism: clinical and biological implications. Microsc Res Tech 2000, 50:216-228.
10. Shen Y.C., Yang T., Wan C., Wang T., Chen L., Wen F.Q. Tumor necrosis factor-alpha polymorphisms and rheumatic heart disease risk: a meta-analysis. Int J Cardiol 2013, 168(3):2878-2880.
11. Vendrell J., Fernandez-Real J.M., Cutierrez C., Zamora A., Simon I., Bardaji A., et al. A polymorphism in the promoter of the tumor necrosis factor-alpha gene (-308) is associated with coronary heart disease in type 2 diabetic patients. Atherosclerosis 2003, 167:257-264.
12. Elahi M.M., Gilmour A., Matata B.M., Mastana S.S. A variant of position -308 of the tumour necrosis factor alpha gene promoter and the risk of coronary heart disease. Heart Lung Circ 2008, 17:14-18.
13. Cho H.C., Yu G., Lee M.Y., Kim H.S., Shin D.H., Kim Y.N. TNF-a polymorphisms and coronary artery disease: association study in the Korean population. Cytokine 2013, 62:104-109.
14. Allen R.A., Lee E.M., Roberts D.H., Park B.K., Pirmohamed M. Polymorphisms in the TNF-alpha and TNF-receptor genes in patients with coronary artery disease. Eur J Clin Invest 2001, 31:843-851.
15. Chu H., Yang J., Mi S., Bhuyan S.S., Li J., Zhong L., Liu S., Tao Z., Li J., Chen H. Tumor necrosis factor-alpha G-308 A polymorphism and risk of coronary heart disease and myocardial infarction: a case-control study and meta-analysis. J Cardiovasc Dis Res 2012, 3:84-90.
16. Ledru F., Ducimetière P., Battaglia S., Courbon D., Beverelli F., Guize L., et al. New diagnostic criteria for diabetes and coronary artery disease: insights from an angiographic study. J Am Coll Cardiol 2001, 37:1543-1550.
17. Kleemann R., Zadelaar S., Kooistra T. Cytokines and atherosclerosis: a comprehensive review of studies in mice. Cardiovasc Res 2008, 79:360-376.
18. Tedgui A., Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev 2006, 86:515-581.
19. Fernandez-Real J.M., Ricart W. Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr Rev 2003, 24:278-301.
20. Pai J.K., Pischon T., Ma J., Manson J.E., Hankinson S.E., Joshipura K., et al. Inflammatory markers and the risk of coronary heart disease in men and women. N Engl J Med 2004, 351:2599-2610.
21. Tuomisto K., Jousilahti P., Sundvall J., Pajunen P., Salomaa V. C-reactive protein, interleukin-6 and tumor necrosis factor alpha as predictors of incident coronary and cardiovascular events and total mortality. A population-based, prospective study. Thromb Haemost 2006, 95:511-518.
22. McMurray J., Abdullah I., Dargie H.J., Shapiro D. Increased concentrations of tumor necrosis factor in "cachectic" patients with severe heart failure. Br Heart J 1999, 66:356-358.
23. Ueland T., Sikkeland L.I., Yndestad A., Eiken H.G., Holm T., Guevara C., et al. Myocardial gene expression of inflammatory cytokines after heart transplantation in relation to the development of transplant coronary artery disease. Am J Cardiol 2003, 92:715-717.
24. Gotsman I., Stabholz A., Planer D., Pugatsch T., Lapidus L., Novikov Y., et al. Serum cytokine tumor necrosis factor-alpha and interleukin-6 associated with the severity of coronary artery disease: indicators of an active inflammatory burden?. Isr Med Assoc J 2008, 10(7):494-498.
25. Bernard V., Pillois X., Dubus I., Benchimol D., Labouyrie J.P., Couffinhal T., et al. The -308 G/A tumor necrosis factor-alpha gene dimorphism: a risk factor for unstable angina. Clin Chem Lab Med 2003, 41(4):511-516.
26. Sbarsi I., Falcone C., Boiocchi C., Campo I., Zorzetto M., De Silvestri A., et al. Inflammation and atherosclerosis: the role of TNF and TNF receptors polymorphisms in coronary artery disease. Int J Immunopathol Pharmacol 2007, 20(1):145-154.
27. Chang W.T., Wang Y.C., Chen C.C., Zhang S.K., Liu C.H., Chang F.H., et al. The -308G/A of tumor necrosis factor (TNF)-α and 825C/T of guanidine nucleotide binding protein 3 (GNB3) are associated with the onset of acute myocardial infarction and obesity in Taiwan. Int J Mol Sci 2012, 13(2):1856-1857.
28. Li Y.Y. Tumor necrosis factor-alpha g308α gene polymorphism and essential hypertension: a meta-analysis involving 2244 participants. PLoS One 2012, 7:e35408.
29. Rehman S., Akhtar N., Saba N., Munir S., Ahmed W., Mohyuddin A., et al. A study on the association of TNF-a-308, IL-6-174, IL-10-1082 and IL-1RaVNTR gene polymorphisms with rheumatic heart disease in Pakistani patients. Cytokine 2013, 61(2):527-531.
30. Wang X.L., Oosterhof J. Tumour necrosis factor a G-308? A polymorphism and risk for coronary artery disease. Clin Sci (Lond) 2000, 98:435-437.
31. Ghazouani L., Khalifa S.B., Abboud N., Addad F., Khalfallah A.B., Brahim N., et al. 308G>A and -1031T>C tumor necrosis factor gene polymorphisms in Tunisian patients with coronary artery disease. Clin Chem Lab Med 2009, 47:1247-1251.
32. Lee Y.H., Harley J.B., Nath S.K. Meta-analysis of TNF-alpha promoter -308 A/G polymorphism and SLE susceptibility. Eur J Hum Genet 2006, 14(3):364-371.
33. Bayley J.P., Ottenhoff T.H., Verweij C.L. Is there a future for TNF promoter polymorphisms?. Genes Immun 2004, 5:315-329.
34. Heijmans B.T., Westendorp R.G., Droog S., Kluft C., Knook D.L., Slagboom P.E. Association of the tumour necrosis factor alpha -308G/A polymorphism with the risk of diabetes in an elderly population-based cohort. Genes Immun 2002, 3:225-228.
35. Wilson A.G., Symons J.A., McDowell T.L., McDevitt H.O., Duff G.W. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA 1997, 94:3195-3199.
36. Abraham L.J., Kroeger K.M. Impact of the -308 TNF promoter polymorphism on the transcriptional regulation of the TNF gene: relevance to disease. J Leukoc Biol 1999, 66:562-566.
37. Lakka H.M., Lakka T.A., Rankinen T., Rice T., Rao D.C., Leon A.S., et al. The TNF-α G-308A polymorphism is associated with C-reactive protein levels: the HERITAGE family study. Vascul Pharmacol 2006, 44(5):377-383.
38. Vatay A., Bene L., Kovács A., Prohászka Z., Szalai C., Romics L., et al. Relationship between the tumor necrosis factor alpha polymorphism and the serum C-reactive protein levels in inflammatory bowel disease. Immunogenetics 2003, 55(4):247-252.
39. Bittles A.H. Population stratification and genetic association studies in South Asia. J Mol Genet Med 2005, 1:43-48.
40. Risch N., Merikangas K. The future of genetic studies of complex human diseases. Science 1996, 273:1516-1517.
41. The PROCARDIS Consortium A trio family study showing association of the lymphotoxin-alpha N26 (804A) allele with coronary artery disease. Eur J Hum Genet 2004, 12:770-774.
42. Shen G.Q., Li L., Girelli D., Seidelmann S.B., Rao S., Fan C., et al. An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction. Am J Hum Genet 2007, 81:780-791.