Plasma microRNAs are associated with atrial fibrillation and change after catheter ablation (the miRhythm study)

Heart Rhythm

Volumn 12, Issue 1, 2015, Pages 3-10

  McManus, David D ^a,b   Tanriverdi, Kahraman ^a   Lin, Honghuang ^b,c   Esa, Nada ^a   Kinno, Menhel ^a   Mandapati, Divakar ^a   Tam, Stanley ^a   Okike, Okike N ^a   Ellinor, Patrick T ^d   Keaney, John F ^a   Donahue, J Kevin ^a   Benjamin, Emelia J ^b,e   Freedman, Jane E ^a,b  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b FRAMINGHAM HEART STUDY   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Arial fibrillation; Circulation; Epidemiology; MicroRNA; Risk factor

Indexed keywords

MICRORNA; MICRORNA 1; MICRORNA 100; MICRORNA 106B; MICRORNA 10B; MICRORNA 122; MICRORNA 125A; MICRORNA 125B; MICRORNA 126; MICRORNA 141; MICRORNA 146A; MICRORNA 150; MICRORNA 155; MICRORNA 19A; MICRORNA 206; MICRORNA 20A; MICRORNA 21; MICRORNA 24; MICRORNA 25; MICRORNA 26A; MICRORNA 29A; MICRORNA 29B; MICRORNA 30A; MICRORNA 30C; MICRORNA 31; MICRORNA 375; MICRORNA 7; MICRORNA 92A; MICRORNA 92B; MIR-106B; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CARDIAC PATIENT; CATHETER ABLATION; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEART ATRIUM FIBRILLATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; AGED; ATRIAL FIBRILLATION; BLOOD; CASE CONTROL STUDY; COHORT ANALYSIS; GENE EXPRESSION REGULATION; HEART ATRIUM; METABOLISM;

ADULT; AGED; ATRIAL FIBRILLATION; CASE-CONTROL STUDIES; CATHETER ABLATION; COHORT STUDIES; FEMALE; GENE EXPRESSION REGULATION; HEART ATRIA; HUMANS; MALE; MICRORNAS; MIDDLE AGED; PROSPECTIVE STUDIES;

EID: 84920678438     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2014.09.050     Document Type: Article

References (35)

1. Benjamin EJ, Wolf PA, D'Agostino RB, Silbershatz H, Kannel WB, Levy D. Impact of atrial fibrillation on the risk of death: the Framingham Heart Study. Circulation 1998;98:946-952.
2. Colilla S, Crow A, Petkun W, Singer DE, Simon T, Liu X. Estimates of current and future incidence and prevalence of atrial fibrillation in the U.S. adult population. Am J Cardiol 2013;112:1142-1147.
3. Alonso A, Krijthe BP, Aspelund T, et al. Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium. J Am Heart Assoc 2013;2:e000102.
4. Fichtlscherer S, De Rosa S, Fox H, et al. Circulating microRNAs in patients with coronary artery disease. Circ Res 2010;107:677-684.
5. Ji X, Takahashi R, Hiura Y, Hirokawa G, Fukushima Y, Iwai N. Plasma mir-208 as a biomarker of myocardial injury. Clin Chem 2009;55:1944-1949.
6. Oliveira-Carvalho V, Silva MM, Guimaraes GV, Bacal F, Bocchi EA. MicroRNAs: new players in heart failure. Mol Biol Rep 2013;40:2663-2670.
7. Girmatsion Z, Biliczki P, Bonauer A, et al. Changes in microRNA-1 expression and ik1 up-regulation in human atrial fibrillation. Heart Rhythm 2009;6:1802-1809.
8. Luo X, Pan Z, Shan H, Xiao J, et al. MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation. J Clin Invest 2013;123:1939-1951.
9. McManus DD, Lin H, Tanriverdi K, Quercio M, Yin X, Larson MG, Ellinor PT, Levy D, Freedman JE, Benjamin EJ. Relations between circulating microRNAs and atrial fibrillation: data from the Framingham Offspring Study. Heart Rhythm 2014;11:663-669.
10. Wang R, Li N, Zhang Y, Ran Y, Pu J. Circulating microRNAs are promising novel biomarkers of acute myocardial infarction. Intern Med 2011;50:1789-1795.
11. Cardin S, Guasch E, Luo X, Naud P, Le Quang K, Shi Y, Tardif JC, Comtois P, Nattel S. Role for microRNA-21 in atrial profibrillatory fibrotic remodeling associated with experimental postinfarction heart failure. Circ Arrhythm Electrophysiol 2012;5:1027-1035.
12. Matkovich SJ, Wang W, Tu Y, Eschenbacher WH, Dorn LE, Condorelli G, Diwan A, Nerbonne JM, Dorn GW. MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res 2010;106:166-175.
13. van Rooij E, Sutherland LB, Thatcher JE, DiMaio JM, Naseem RH, Marshall WS, Hill JA, Olson EN. Dysregulation of microRNAs after myocardial infarction reveals a role of mir-29 in cardiac fibrosis. Proc Natl Acad Sci U S A 2008;105:13027-13032.
14. De Rosa S, Fichtlscherer S, Lehmann R, Assmus B, Dimmeler S, Zeiher AM. Transcoronary concentration gradients of circulating microRNAs. Circulation 2011;124:1936-1944.
15. Dong S, Cheng Y, Yang J, Li J, Liu X, Wang X, Wang D, Krall TJ, Delphin ES, Zhang C. MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction. J Biol Chem 2009;284:29514-29525.
16. Dawson K, Wakili R, Ordog B, et al. MicroRNA29: a mechanistic contributor and potential biomarker in atrial fibrillation. Circulation 2013;127:1466-1475.
17. Nattel S, Harada M. Atrial remodeling and atrial fibrillation: recent advances and translational perspectives. J Am Coll Cardiol 2014;63:2335-2345.
18. Barth AS, Merk S, Arnoldi E, et al. Reprogramming of the human atrial transcriptome in permanent atrial fibrillation: expression of a ventricular-like genomic signature. Circ Res 2005;96:1022-1029.
19. Liu Z, Zhou C, Liu Y, Wang S, Ye P, Miao X, Xia J. The expression levels of plasma micoRNAs in atrial fibrillation patients. PloS One 2012;7:e44906.
20. Adam O, Lohfelm B, Thum T, Gupta SK, Puhl SL, Schafers HJ, Bohm M, Laufs U. Role of mir-21 in the pathogenesis of atrial fibrosis. Basic Res Cardiol 2012;107:278.
21. Lu Y, Zhang Y, Wang N, et al. MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation. Circulation 2010;122:2378-2387.
22. Goren Y, Meiri E, Hogan C, Mitchell H, Lebanony D, Salman N, Schliamser JE, Amir O. Relation of reduced expression of mir-150 in platelets to atrial fibrillation in patients with chronic systolic heart failure. Am J Cardiol 2014;113:976-981.
23. de Boer HC, van Solingen C, Prins J, Duijs JM, Huisman MV, Rabelink TJ, van Zonneveld AJ. Aspirin treatment hampers the use of plasma microRNA-126 as a biomarker for the progression of vascular disease. Eur Heart J 2013;34:3451-3457.
24. Markides V, Schilling RJ. Atrial fibrillation: classification, pathophysiology, mechanisms and drug treatment. Heart 2003;89:939-943.
25. Small EM, Olson EN. Pervasive roles of microRNAs in cardiovascular biology. Nature 2011;469:336-342.
26. van Rooij E, Sutherland LB, Liu N, Williams AH, McAnally J, Gerard RD, Richardson JA, Olson EN. A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci U S A 2006;103:18255-18260.
27. Jang JS, Simon VA, Feddersen RM, Rakhshan F, Schultz DA, Zschunke MA, Lingle WL, Kolbert CP, Jen J. Quantitative miRNA expression analysis using fluidigm microfluidics dynamic arrays. BMC Genomics 2011;12:144.
28. Wang GK, Zhu JQ, Zhang JT, Li Q, Li Y, He J, Qin YW, Jing Q. Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans. Eur Heart J. 2010;31:659-666.
29. D'Haene B, Mestdagh P, Hellemans J, Vandesompele J. MiRNA expression profiling: from reference genes to global mean normalization. Methods Mol Biol 2012;822:261-272.
30. Zuo ML, Liu S, Chan KH, et al. The CHADS 2 and CHA 2DS 2-VASc scores predict new occurrence of atrial fibrillation and ischemic stroke. J Interv Card Electrophysiol 2013;37:47-54.
31. Yao Y, Zhou X, Wang XB, Duan XX, Zhang CX, Shi XL, Chen Z, Fan ZC. Changes in cardiac specific microRNA-208a level in peripheral blood in st segment elevation acute myocardial infarction patients. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2012;24:717-720.
32. Reddy ST, Belden W, Doyle M, Thompson DV, Williams R, Yamrozik J, Shah M, Biederman RW. Mitral regurgitation recovery and atrial reverse remodeling following pulmonary vein isolation procedure in patients with atrial fibrillation: a clinical observation proof-of-concept cardiac mri study. J Interv Card Electrophysiol 2013;37:307-315.
33. Liebetrau C, Mollmann H, Dorr O, et al. Release kinetics of circulating muscle-enriched microRNAs in patients undergoing transcoronary ablation of septal hypertrophy. J Am Coll Cardiol 2013;62:992-998.
34. Kumarswamy R, Volkmann I, Thum T. Regulation and function of miRNA-21 in health and disease. RNA Biol 2011;8:706-713.
35. Adam O, Lavall D, Theobald K, et al. Rac1-induced connective tissue growth factor regulates connexin 43 and n-cadherin expression in atrial fibrillation. J Am Coll Cardiol 2010;55:469-480.