Dextran and its potential use as tablet excipient

Powder Technology

Volumn 273, Issue , 2015, Pages 125-132

  Casettari, Luca ^a   Bonacucina, Giulia ^b   Morris, Gordon A ^c   Perinelli, Diego R ^b   Lucaioli, Paolo ^b   Cespi, Marco ^b   Palmieri, Giovanni Filippo ^b  

^a UNIVERSITY OF URBINO   (Italy)

^b UNIVERSITY OF CAMERINO   (Italy)

^c UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

Author keywords

Dextran; Drug release; Swelling; Tabletability; Tramadol

Indexed keywords

DISSOLUTION; DRUG DELIVERY; DRUG PRODUCTS; MOLECULAR WEIGHT; PARTICLE SIZE; SWELLING;

CARBOHYDRATE POLYMERS; DRUG DELIVERY SYSTEM; DRUG RELEASE; GEL-FORMING ABILITY; HYDROPHILIC MATRIX; PHARMACEUTICAL APPLICATIONS; TABLETABILITY; TRAMADOL;

DEXTRAN;

DEXTRAN; HYDROXYPROPYLMETHYLCELLULOSE; TRAMADOL;

ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG STABILITY; MOLECULAR WEIGHT; PARTICLE SIZE; TABLET; TABLET FORMULATION; WETTABILITY;

EID: 84920672586     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2014.12.030     Document Type: Article

References (41)

1. Morris G., Harding S. Polysaccharides, microbial. Encyclopedia of Microbiology 2009, 482-494. Academic Press, Oxford. Third edition. M. Schaechter (Ed.).
2. Khalikova E., Susi P., Korpela T. Microbial dextran-hydrolyzing enzymes: fundamentals and applications. Microbiol. Mol. Biol. Rev. 2005, 69:306-325.
3. Mehvar R. Dextrans for targeted and sustained delivery of therapeutic and imaging agents. J. Control. Release 2000, 69:1-25.
4. Lin C., Song Y., Lou B., Zhao P. Dextranation of bioreducible cationic polyamide for systemic gene delivery. Biomed. Mater. Eng. 2014, 24:673-682.
5. Li F., Pei D., Huang Q., Shi T., Zhang G. Synthesis and properties of novel biomimetic and thermo-responsive dextran-based biohybrids. Carbohydr. Polym. 2014, 99:728-735.
6. Varshosaz J. Dextran conjugates in drug delivery. Expert Opin. Drug Deliv. 2012, 9:509-523.
7. Chalasani K.B., Russell-Jones G.J., Jain A.K., Diwan P.V., Jain S.K. Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles. J. Control. Release 2007, 122:141-150.
8. Chalasani K.B., Russell-Jones G.J., Yandrapu S.K., Diwan P.V., Jain S.K. A novel vitamin B12-nanosphere conjugate carrier system for peroral delivery of insulin. J. Control. Release 2007, 117:421-429.
9. Larsen C. Dextran prodrugs - structure and stability in relation to therapeutic activity. Adv. Drug Deliv. Rev. 1989, 3:103-154.
10. Moriyama K., Yui N. Regulated insulin release from biodegradable dextran hydrogels containing poly(ethylene glycol). J. Control. Release 1996, 42:237-248.
11. Fülöp Z., Nielsen T.T., Larsen K.L., Loftsson T. Dextran-based cyclodextrin polymers: their solubilizing effect and self-association. Carbohydr. Polym. 2013, 97:635-642.
12. Basan H., Gümüşderelioğlu M., Tevfik Orbey M. Release characteristics of salmon calcitonin from dextran hydrogels for colon-specific delivery. Eur. J. Pharm. Biopharm. 2007, 65:39-46.
13. Hovgaard L., Brøndsted H. Dextran hydrogels for colon-specific drug delivery. J. Control. Release 1995, 36:159-166.
14. Varshosaz J., Ahmadi F., Emami J., Tavakoli N., Minaiyan M., Mahzouni P., Dorkoosh F. Colon delivery of budesonide using solid dispersion in Dextran for the treatment and secondary prevention of ulcerative colitis in Rat. Int. J. Prev. Med. 2010, 1:115-123.
15. Varshosaz J., Emami J., Tavakoli N., Fassihi A., Minaiyan M., Ahmadi F., Dorkoosh F. Synthesis and evaluation of dextran-budesonide conjugates as colon specific prodrugs for treatment of ulcerative colitis. Int. J. Pharm. 2009, 365:69-76.
16. Nakade S., Komaba J., Ohno T., Kitagawa J., Furukawa K., Miyata Y. Bioequivalence study of two limaprost alfadex 5μg tablets in healthy subjects: moisture-resistant tablet (dextran formulation) versus standard tablet (lactose formulation). Int. J. Clin. Pharmacol. Ther. 2008, 46:42-47.
17. Sekiya N., Abe N., Yamamoto M., Takeda K. Improved stability of OPALMON® tablets under humid conditions. III: application of the rotary vacuum drying method to dry opalmon tablets. Chem. Pharm. Bull. 2007, 55:546-550.
18. Sekiya N., Nishiwaki A., Nishiura A., Yamamoto M., Takeda K., Iohara D., Hirayama F., Arima H., Uekama K. Improved stability of Opalmon® tablets under humid conditions IV: effect of polysaccharides and disintegrants on the stability and dissolution property of Opalmon® tablets. Chem. Pharm. Bull. 2008, 56:7-11.
19. Gil E.C., Colarte A.I., Bataille B., Pedraz J.L., Rodríguez F., Heinämäki J. Development and optimization of a novel sustained-release dextran tablet formulation for propranolol hydrochloride. Int. J. Pharm. 2006, 317:32-39.
20. Gil E.C., Colarte A.I., Bataille B., Caraballo I. Estimation of the percolation thresholds in lobenzarit disodium native dextran matrix tablets. AAPS PharmSciTech 2007, 8.
21. Gil E.C., Colarte A.I., El Ghzaoui A., Durand D., Delarbre J.L., Bataille B. A sugar cane native dextran as an innovative functional excipient for the development of pharmaceutical tablets. Eur. J. Pharm. Biopharm. 2008, 68:319-329.
22. Efentakis M., Atsidakos G. Design and evaluation of oral delivery formulations based on dextran with theophylline. Int. J. Drug Deliv. 2012, 4:515-522.
23. Körner A., Piculell L., Iselau F., Wittgren B., Larsson A. Influence of different polymer types on the overall release mechanism in hydrophilic matrix tablets. Molecules 2009, 14:2699-2716.
24. Cespi M., Misici-Falzi M., Bonacucina G., Ronchi S., Palmieri G.F. The effect of punch tilting in evaluating powder densification in a rotary tablet machine. J. Pharm. Sci. 2008, 97:1277-1284.
25. Palmieri G.F., Joiris E., Bonacucina G., Cespi M., Mercuri A. Differences between eccentric and rotary tablet machines in the evaluation of powder densification behaviour. Int. J. Pharm. 2005, 298:164-175.
26. Traynor M.J., Brown M.B., Pannala A., Beck P., Martin G.P. Influence of alcohol on the release of tramadol from 24-h controlled-release formulations during in vitro dissolution experiments. Drug Dev. Ind. Pharm. 2008, 34:885-889.
27. Selvaraj B., Malarvizhi P., Shanmugapandiyan P. Development and in vitro characterization of Tramadol Hydrochloride sustained release tablets. Int. J. PharmTech Res. 2013, 5:492-500.
28. Roberts M., Cespi M., Ford J.L., Dyas A.M., Downing J., Martini L.G., Crowley P.J. Influence of ethanol on aspirin release from hypromellose matrices. Int. J. Pharm. 2007, 332:31-37.
29. Elversson J., Millqvist-Fureby A. Particle size and density in spray drying-effects of carbohydrate properties. J. Pharm. Sci. 2005, 94:2049-2060.
30. Kho K., Hadinoto K. Aqueous re-dispersibility characterization of spray-dried hollow spherical silica nano-aggregates. Powder Technol. 2010, 198:354-363.
31. Learoyd T.P., Burrows J.L., French E., Seville P.C. Chitosan-based spray-dried respirable powders for sustained delivery of terbutaline sulfate. Eur. J. Pharm. Biopharm. 2008, 68:224-234.
32. Zografi G., Kontny M.J. The interactions of water with cellulose- and starch-derived pharmaceutical excipients. Pharm. Res. 1986, 3:187-194.
33. Amidon G.E., Houghton M.E. The effect of moisture on the mechanical and powder flow properties of microcrystalline cellulose. Pharm. Res. 1995, 12:923-929.
34. Hancock B.C., Shamblin S.L. Water vapour sorption by pharmaceutical sugars. Pharm. Sci. Technol. Today 1998, 1:345-351.
35. Cespi M., Bonacucina G., Roberts M., Hanson S., Jones S., Makevica E., Casettari L., Palmieri G.F. Evaluation of citrus fibres as a tablet excipient. AAPS PharmSciTech 2014, 15:279-286.
36. Cespi M., Bonacucina G., Casettari L., Ronchi S., Palmieri G.F. Effect of temperature increase during the tableting of pharmaceutical materials. Int. J. Pharm. 2013, 448:320-326.
37. Rees J.E., Tsardaka K.D. Some effects of moisture on the viscoelastic behaviour of modified starch during powder compaction. Eur. J. Pharm. Biopharm. 1994, 40:193-197.
38. Van der Voort Maarschalk K., Vromans H., Groenendijk W., Bolhuis G.K., Lerk C.F. Effect of water on deformation and bonding of pregelatinized starch compacts. Eur. J. Pharm. Biopharm. 1997, 44:253-260.
39. Cespi M., Bonacucina G., Misici-Falzi M., Golzi R., Boltri L., Palmieri G.F. Stress relaxation test for the characterization of the viscoelasticity of pellets. Eur. J. Pharm. Biopharm. 2007, 67:476-484.
40. Rajabi-Siahboomi A.R. Structure and behaviour in hydrophilic matrix sustained release dosage forms: 2. NMR-imaging studies of dimensional changes in the gel layer and core of HPMC tablets undergoing hydration. J. Control. Release 1994, 31:121-128.
41. Colombo P., Conte U., Gazzaniga A., Maggi L., Sangalli M.E., Peppas N.A., La Manna A. Drug release modulation by physical restrictions of matrix swelling. Int. J. Pharm. 1990, 63:43-48.