Improved stability of Opalmon® tablets under humid conditions IV: Effect of polysaccharides and disintegrants on the stability and dissolution property of Opalmon® tablets

Chemical and Pharmaceutical Bulletin

Volumn 56, Issue 1, 2008, Pages 7-11

  Sekiya, Noboru ^a   Nishiwaki, Atsushi ^a   Nishiura, Akio ^a   Yamamoto, Masanobu ^a   Takeda, Kazuhisa ^a   Iohara, Daisuke ^b   Hirayama, Fumitoshi ^b   Arima, Hidetoshi ^c   Uekama, Kaneto ^b  

^a ONO PHARMACEUTICAL CO   (Japan)

^b SOJO UNIVERSITY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Dissolution; Formulation; Limaprost alfadex; Opalmon; Stability

Indexed keywords

ALPHA CYCLODEXTRIN; DEXTRAN; DEXTRIN; DISINTEGRATING AGENT; LACTOSE; LIMAPROST ALFADEX; OPALMON; PROSTAGLANDIN DERIVATIVE; UNCLASSIFIED DRUG; ALPHA CYCLODEXTRIN DERIVATIVE; DISINTEGRIN; DRUG DERIVATIVE; EXCIPIENT; LIMAPROST; LIMAPROST-ALFADEX; POLYSACCHARIDE; PROSTAGLANDIN E1;

ARTICLE; DRUG DEGRADATION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; HUMIDITY; SOLUBILITY; TABLET;

ALPHA-CYCLODEXTRINS; ALPROSTADIL; DEXTRANS; DEXTRINS; DISINTEGRINS; EXCIPIENTS; HUMIDITY; MOLECULAR STRUCTURE; POLYSACCHARIDES; SOLUBILITY; TABLETS;

EID: 38049123922     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.56.7     Document Type: Article

References (8)

1. Sekiya N., Yamamoto M., Nishiwaki A., Nishiura A., Takeda K., Yakuzaigaku, 66, 160-166 (2006).
2. Sekiya N., Abe N., Ishikawa H., Inoue Y., Yamamoto M., Takeda K., Jpn. J. Pharm. Health Care Sci., 32, 482-488 (2006).
3. "Guideline for Bioequivalence Studies for Formulation Changes of Oral Solid Dosage Forms," National Institute of Health Science, Japan, 2006.
4. Moribe K., Sekiya N., Fujito T., Yamamoto M., Higashi K., Yokohama C., Tozuka Y., Yamamoto K., Int. J. Pharm., 338, 1-6 (2007).
5. Yamamoto M., Hirayama F., Uekama K., Chem. Pharm. Bull., 40, 747-751 (1992).
6. Hirayama F., Uekama K., Koinuma H., Chem. Pharm. Bull., 28, 1975-1980 (1980).
7. Uekama K., Hirayama F., Chem. Pharm. Bull., 26, 1195-1200 (1978).
8. Uekama K., Hieda Y., Hirayama F., Arima H., Sudoh M., Yagi A., Terashima H., Pharm. Res., 18, 1578-1585 (2001).