P16 expression in patients with cervical cancer and its prognostic significance: Meta-analysis of published literature

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 183, Issue , 2014, Pages 64-69

  Huang, K ^a   Li, L A ^a   Meng, Y G ^a   Fu, X Y ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Meta analysis; p16 Immunohistochemistry; Survival

Indexed keywords

PROTEIN P16; P16 PROTEIN, HUMAN; TUMOR MARKER; TUMOR PROTEIN;

ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; DISEASE FREE SURVIVAL; HUMAN; META ANALYSIS; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTEMATIC REVIEW; UTERINE CERVIX CANCER; BIOPSY; CANCER STAGING; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MORTALITY; PATHOLOGY; PREDICTIVE VALUE; PROGNOSIS; SURVIVAL RATE; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX TUMOR;

BIOPSY; CERVICAL INTRAEPITHELIAL NEOPLASIA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM PROTEINS; NEOPLASM STAGING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS;

EID: 84920649700     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2014.10.016     Document Type: Article

References (27)

1. INK4A immunohistochemical staining and predictive value for progression of cervical intraepithelial neoplasia grade 1: a prospective study in China Int J Cancer 134 2014 1715 1724
2. INK4A is necessary for survival of cervical carcinoma cell lines Proc Natl Acad Sci U S A 110 2013 16175 16180
3. P. Agarwal, F.M.L. Kabir, P. Deinnocentes, and R.C. Bird Tumor suppressor gene p16/INK4A/CDKN2A and its role in cell cycle exit, differentiation, and determination of cell fate Tumor suppressor genes 2012 InTech Open Access Publisher Rijeka 1 34
4. INK4a , pRb, p53 and Ki-67 expression in cervical squamous neoplasia J Biomed Res 13 2012 209 217
5. D.G. Altman Systematic reviews of evaluations of prognostic variables Br Med J 323 2001 224 228
6. M.K. Parmar, V. Torri, and L. Stewart Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints Stat Med 17 1998 2815 2834
7. R. DerSimonian, and N. Laird Meta-analysis in clinical trials Control Clin Trials 7 1986 177 188
8. J.P. Higgins, S.G. Thompson, J.J. Deeks, and D.G. Altman Measuring inconsistency in meta-analyses Br Med J 327 2003 557
9. M. Egger, and G.D. Smith Bias in location and selection of studies Br Med J 316 1998 61 66
10. INK4/MTS1 in adenocarcinomas of the uterine cervix Cancer 98 2003 1880 1889
11. G. Van de Putte, R. Holm, A.K. Lie, C.G. Trop, and G.B. Kristensen Expression of p27, p21, and p16 protein in early squamous cervical cancer and its relation to prognosis Gynecol Oncol 89 2003 140 147
12. H. Masoudi, D. Van Niekerk, and C. Gilks Loss of p16 INK4 expression in invasive squamous cell carcinoma of the uterine cervix is an adverse prognostic marker Histopathology 49 2006 542 545
13. K. Bodner, P. Laubichler, O. Kimberger, K. Czerwenka, R. Zeillinger, and B. Bodner-Adler Expression of p16 protein and epidermal growth factor receptor in patients with adenocarcinoma of the uterine cervix: an immunohistochemical analysis Arch Gynecol Obstet 283 2011 611 616
14. J.K. Schwarz, J.S. Lewis Jr., J. Pfeifer, P. Huettner, and P. Grigsby Prognostic significance of p16 expression in advanced cervical cancer treated with definitive radiotherapy Int J Radiat Oncol Biol Phys 84 2012 153 157
15. INK4A overexpression predicts lymph node metastasis in cervical carcinomas J Clin Pathol 65 2012 117 121
16. X. Li The prognostic value of p16 expression in cervical cancer centre Chin Med J 24 2000 85 86
17. C.R. Han, Z.Q. Li, and J.B. Yu The expression and clincal significance of p16 and p15 in cervical carcinoma J Mudanjiang Med Coll 25 2004 1 5
18. INK4a in cervical cancer Hainan Med 18 2007 44 45
19. T. Jiang, L.Y. Li, M. Pan, S.Y. Zeng, Z.Q. Qiao, and W.Y. Wu The prognostic impact of p16 in cervical cancer Pract J Cancer 20 2005 581 583
20. G.E. Konecny, B. Winterhoff, and T. Kolarova Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer Clin Cancer Res 17 2011 1591 1602
21. INK4A overexpression in precancerous and cancerous lesions of the uterine cervix in Tunisian women Pathol Res Pract 206 2010 550 555
22. M. Helbig, T. Andl, and T. Kahn The role of oncogenic human papillomaviruses in tonsillar squamous cell carcinomas with functional inactivation of the retinoblastoma protein HNO 47 1999 796 803
23. INK4a -positive cells in cervical cytology samples Acta Cytol 48 2011 771 782
24. INK4a immunostaining in cytological and histological specimens from the uterine cervix: a systematic review and meta-analysis Cancer Treat Rev 35 2009 210 220
25. S. de Sanjose, W.G. Quint, and L. Alemany Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study Lancet Oncol 11 2010 1048 1056
26. Ink4a overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors Oncogene 30 2011 2087 2097
27. F. Zhao, Y. Chen, Q. Wu, Z. Wang, and J. Lu Prognostic value of CD117 in cancer: a meta-analysis Int J Clin Exp Pathol 7 2014 1012 1021