Hypothalamic-pituitary-adrenal axis activity in older persons with and without a depressive disorder

Psychoneuroendocrinology

Volumn 51, Issue , 2015, Pages 341-350

  Rhebergen, D ^a   Korten, N C M ^a   Penninx, B W J H ^a   Stek, M L ^a   van der Mast, R C ^b   Oude Voshaar, R ^c,d   Comijs, H C ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cortisol; Depression; HPA axis; Older persons

Indexed keywords

ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; HYDROCORTISONE; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; AGED; ANALYSIS OF COVARIANCE; ANXIETY; AROUSAL; ARTICLE; BRAIN FUNCTION; CHEMILUMINESCENCE IMMUNOASSAY; CIRCADIAN RHYTHM; CONTROLLED STUDY; DEXAMETHASONE SUPPRESSION TEST; DISEASE ASSOCIATION; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPERCORTISOLISM; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LIFESTYLE; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MENTAL DISEASE; MENTAL HEALTH CARE; MINI MENTAL STATE EXAMINATION; NETHERLANDS; PHYSICAL ACTIVITY; SALIVA ANALYSIS; SYMPTOMATOLOGY; CHEMISTRY; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; SALIVA;

AGED; CIRCADIAN RHYTHM; DEPRESSIVE DISORDER, MAJOR; FEMALE; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MIDDLE AGED; NETHERLANDS; PITUITARY-ADRENAL SYSTEM; SALIVA;

EID: 84920606466     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2014.10.005     Document Type: Article

References (35)

1. American Psychiatric Association The dexamethasone suppression test: an overview of its current status in psychiatry. The APA task force on laboratory tests in psychiatry. Am. J. Psychiatry 1987, 144:1256-1262.
2. Balardin J.B., Vedana G., Luz C., Bromberg E. Subjective mild depressive symptoms are associated with abnormal diurnal cycle of salivary cortisol in older adults. J. Geriatr. Psychiatry Neurol. 2011, 24:19-22.
3. Belvederi Murri M., Pariante C., Mondelli V., Masotti M., Atti A.R., Mellacqua Z., Antonioli M., Ghio L., Menchetti M., Zanetidou S., Innamorati M., Amore M. HPA axis and aging in depression: systematic review and meta-analysis. Psychoneuroendocrinology 2014, 41:46-62.
4. Bhattacharyya M.R., Molloy G.J., Steptoe A. Depression is associated with flatter cortisol rhythms in patients with coronary artery disease. J. Psychosom. Res. 2008, 65:107-113.
5. Bremmer M.A., Deeg D.J.H., Beekman A.T.F., Penninx B.W.J.H., Lips P., Hoogendijk W.J.G. Major depression in late life is associated with both hypo- and hypercortisolemia. Biol. Psychiatry 2007, 62:479-486.
6. Brown E.S., Varghese F.P., McEwen B.S. Association of depression with medical illness: does cortisol play a role?. Biol. Psychiatry 2004, 55:1-9.
7. Comijs H.C., van Marwijk H.W., van der Mast R.C., Naarding P., Oude Voshaar R.C., Beekman A.T., Boshuisen M., Dekker J., Kok R., de Waal M.W., Penninx B.W., Stek M.L., Smit J.H. The Netherlands study of depression in older persons (NESDO); a prospective cohort study. BMC Res. Notes 2011, 4:524.
8. Craig C.L., Marshall A.L., Sjostrom M., Bauman A.E., Booth M.L., Ainsworth B.E., Pratt M., Ekelund U., Yngve A., Sallis J.F., Oja P. International physical activity questionnaire: 12-country reliability and validity. Med. Sci. Sports Exerc. 2003, 35:1381-1395.
9. Edwards S., Clow A., Evans P., Hucklebridge F. Exploration of the awakening cortisol response in relation to diurnal cortisol secretory activity. Life Sci. 2001, 68:2093-2103.
10. Fekedulegn D.B., Andrew M.E., Burchfiel C.M., Violanti J.M., Hartley T.A., Charles L.E., Miller D.B. Area under the curve and other summary indicators of repeated waking cortisol measurements. Psychosom. Med. 2007, 69:651-659.
11. Fiocco A.J., Wan N., Weekes N., Pim H., Lupien S.J. Diurnal cycle of salivary cortisol in older adult men and women with subjective complaints of memory deficits and/or depressive symptoms: relation to cognitive functioning. Stress 2006, 9:143-152.
12. Heaney J.L., Phillips A.C., Carroll D. Ageing, depression, anxiety, social support and the diurnal rhythm and awakening response of salivary cortisol. Int. J. Psychophysiol. 2010, 78:201-208.
13. Johar H., Emeny R.T., Bidlingmaier M., Reincke M., Thorand B., Peters A., Heier M., Ladwig K.H. Blunted diurnal cortisol pattern is associated with frailty: a cross-sectional study of 745 participants aged 65 to 90 years. J. Clin. Endocrinol. Metab. 2014, 99:E464-E468.
14. Kohler S., Thomas A.J., Lloyd A., Barber R., Almeida O.P., O'Brien J.T. White matter hyperintensities, cortisol levels, brain atrophy and continuing cognitive deficits in late-life depression. Br. J. Psychiatry 2010, 196:143-149.
15. Kriegsman D.M., Penninx B.W., van Eijk J.T., Boeke A.J., Deeg D.J. Self-reports and general practitioner information on the presence of chronic diseases in community dwelling elderly. A study on the accuracy of patients' self-reports and on determinants of inaccuracy. J. Clin. Epidemiol. 1996, 49:1407-1417.
16. Lamers F., Vogelzangs N., Merikangas K.R., De Jonge P., Beekman A.T.F., Penninx B.W.J.H. Evidence for a differential role of HPA-axis function, inflammation and metabolic syndrome in melancholic versus atypical depression. Mol. Psychiatry 2013, 18:692-699.
17. Mannie Z.N., Harmer C.J., Cowen P.J. Increased waking salivary cortisol levels in young people at familial risk of depression. Am. J. Psychiatry 2007, 164:617-621.
18. Miller G.E., Chen E., Zhou E.S. If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans. Psychol. Bull. 2007, 133:25-45.
19. Morrison M.F., Redei E., TenHave T., Parmelee P., Boyce A.A., Sinha P.S., Katz I.R. Dehydroepiandrosterone sulfate and psychiatric measures in a frail, elderly residential care population. Biol. Psychiatry 2000, 47:144-150.
20. Nelson J.C., Davis J.M. DST studies in psychotic depression: a meta-analysis. Am. J. Psychiatry 1997, 154:1497-1503.
21. O'Brien J.T., Lloyd A., McKeith I., Gholkar A., Ferrier N. A longitudinal study of hippocampal volume, cortisol levels, and cognition in older depressed subjects. Am. J. Psychiatry 2004, 161:2081-2090.
22. Oldehinkel A.J., van D.B., Flentge F., Bouhuys A.L., ter Horst G.J., Ormel J. Urinary free cortisol excretion in elderly persons with minor and major depression. Psychiatry Res. 2001, 104:39-47.
23. Penninx B.W.J.H., Beekman A.T.F., Bandinelli S., Corsi A.M., Bremmer M., Hoogendijk W.J., Guralnik J.M., Ferrucci L. Late-life depressive symptoms are associated with both hyperactivity and hypoactivity of the hypothalamo-pituitary-adrenal axis. Am. J. Geriatr. Psychiatry 2007, 15:522-529.
24. Pruessner J.C., Kirschbaum C., Meinlschmid G., Hellhammer D.H. Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change. Psychoneuroendocrinology 2003, 28:916-931.
25. Rush A.J., Gullion C.M., Basco M.R., Jarrett R.B., Trivedi M.H. The inventory of depressive symptomatology (IDS): psychometric properties. Psychol. Med. 1996, 26:477-486.
26. Schmidt-Reinwald A., Pruessner J.C., Hellhammer D.H., Federenko I., Rohleder N., Schurmeyer T.H., Kirschbaum C. The cortisol response to awakening in relation to different challenge tests and a 12-hour cortisol rhythm. Life Sci. 1999, 64:1653-1660.
27. Stetler C., Miller G.E. Depression and hypothalamic-pituitary-adrenal activation: a quantitative summary of four decades of research. Psychosom. Med. 2011, 73:114-126.
28. Terzidis K., Panoutsopoulos A., Mantzou A., Tourli P., Papageorgiou G., Saltiki K., Tsagalis G., Mara C., Alevizaki M. Cortisol levels and metabolic parameters in middle- and advanced- age subjects: associations with age. J. Endocrinol. Invest. 2011, 34:e398-e402.
29. Varadhan R., Walston J., Cappola A.R., Carlson M.C., Wand G.S., Fried L.P. Higher levels and blunted diurnal variation of cortisol in frail older women. J. Gerontol. A: Biol. Sci. Med. Sci. 2008, 63:190-195.
30. Vreeburg S.A., Hoogendijk W.J., van P.J., Derijk R.H., Verhagen J.C., van D.R., Smit J.H., Zitman F.G., Penninx B.W. Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study. Arch. Gen. Psychiatry 2009, 66:617-626.
31. Vreeburg S.A., Kruijtzer B.P., van P.J., van D.R., Derijk R.H., Hoogendijk W.J., Smit J.H., Zitman F.G., Penninx B.W. Associations between sociodemographic, sampling and health factors and various salivary cortisol indicators in a large sample without psychopathology. Psychoneuroendocrinology 2009, 34:1109-1120.
32. Wikgren M., Maripuu M., Karlsson T., Nordfjall K., Bergdahl J., Hultdin J., Del-Favero J., Roos G., Nilsson L.G., Adolfsson R., Norrback K.F. Short telomeres in depression and the general population are associated with a hypocortisolemic state. Biol. Psychiatry 2012, 71:294-300.
33. Wittchen H.U. Reliability and validity studies of the WHO-composite international diagnostic interview (CIDI): a critical review. J. Psychiatr. Res. 1994, 28:57-84.
34. Wittchen H.U., Robins L.N., Cottler L.B., Sartorius N., Burke J.D., Regier D. Cross-cultural feasibility, reliability and sources of variance of the composite international diagnostic interview (CIDI). The multicentre WHO/ADAMHA field trials. Br. J. Psychiatry 1991, 159:645-653. 658.
35. World Health Organization Collaborating Centre for Drug Statistics Methodology Anatomical therapeutic chemical (ATC) classification 2010.