Effects of adjunctive daily phototherapy on chronic periodontitis: A randomized single-blind controlled trial

Journal of Periodontal and Implant Science

Volumn 44, Issue 6, 2014, Pages 280-287

  Jung, Gyu Un ^a   Kim, Jin Woo ^b   Kim, Sun Jong ^b   Pang, Eun Kyoung ^a,c  

^a Ewha Womans University   (South Korea)

^b Ewha Womans University   (South Korea)

^c Ewha Womans University School of Medicine   (South Korea)

Author keywords

Dental scaling; Periodontal index; Periodontitis; Photochemotherapy; Photosensitizing agents

Indexed keywords

EID: 84920589053     PISSN: 20932278     EISSN: 20932286     Source Type: Journal    
DOI: 10.5051/jpis.2014.44.6.280     Document Type: Article

References (35)

1. Renvert S, Dahlen G, Wikstrom M. Treatment of periodontal disease based on microbiological diagnosis: relation between microbiological and clinical parameters during 5 years. J Periodontol 1996;67:562-71.
2. Haffajee AD. Systemic antibiotics: to use or not to use in the treatment of periodontal infections: that is the question. J Clin Periodontol 2006;33:359-61.
3. Darveau RP, Tanner A, Page RC. The microbial challenge in periodontitis. Periodontol 2000 1997;14:12-32.
4. Soukos NS, Goodson JM. Photodynamic therapy in the control of oral biofilms. Periodontol 2000 2011;55:143-66.
5. Diamond I, Granelli SG, McDonagh AF, Nielsen S, Wilson CB, Jaenicke R. Photodynamic therapy of malignant tumours. Lancet 1972; 2:1175-7.
6. Braun A, Dehn C, Krause F, Jepsen S. Short-term clinical effects of adjunctive antimicrobial photodynamic therapy in periodontal treatment: a randomized clinical trial. J Clin Periodontol 2008; 35:877-84.
7. Ge L, Shu R, Li Y, Li C, Luo L, Song Z, et al. Adjunctive effect of photodynamic therapy to scaling and root planing in the treatment of chronic periodontitis. Photomed Laser Surg 2011;29:33-7.
8. Sigusch BW, Pfitzner A, Albrecht V, Glockmann E. Efficacy of photodynamic therapy on inflammatory signs and two selected periodontopathogenic species in a beagle dog model. J Periodontol 2005;76:1100-5.
9. O'Neill JF, Hope CK, Wilson M. Oral bacteria in multi-species biofilms can be killed by red light in the presence of toluidine blue. Lasers Surg Med 2002;31:86-90.
10. Soukos NS, Socransky SS, Mulholland SE, Lee S, Doukas AG. Photomechanical drug delivery into bacterial biofilms. Pharm Res 2000;17:405-9.
11. Balata ML, Andrade LP, Santos DB, Cavalcanti AN, Tunes Uda R, Ribeiro Edel P, et al. Photodynamic therapy associated with full-mouth ultrasonic debridement in the treatment of severe chronic periodontitis: a randomized-controlled clinical trial. J Appl Oral Sci 2013;21:208-14.
12. Andersen R, Loebel N, Hammond D, Wilson M. Treatment of periodontal disease by photodisinfection compared to scaling and root planing. J Clin Dent 2007;18:34-8.
13. Betsy J, Prasanth CS, Baiju KV, Prasanthila J, Subhash N. Efficacy of antimicrobial photodynamic therapy in the management of chronic periodontitis: a randomized controlled clinical trial. J Clin Periodontol 2014;41:573-81.
14. Fukui M, Yoshioka M, Satomura K, Nakanishi H, Nagayama M. Specific-wavelength visible light irradiation inhibits bacterial growth of Porphyromonas gingivalis. J Periodontal Res 2008; 43:174-8.
15. de Almeida JM, Theodoro LH, Bosco AF, Nagata MJ, Oshiiwa M, Garcia VG. Influence of photodynamic therapy on the development of ligature-induced periodontitis in rats. J Periodontol 2007; 78:566-75.
16. Smalley JW, Birss AJ, Withnall R, Silver J. Interactions of Porphyromonas gingivalis with oxyhaemoglobin and deoxyhaemoglobin. Biochem J 2002;362(Pt 1):239-45.
17. Soukos NS, Som S, Abernethy AD, Ruggiero K, Dunham J, Lee C, et al. Phototargeting oral black-pigmented bacteria. Antimicrob Agents Chemother 2005;49:1391-6.
18. Silness J, Loe H. Periodontal disease in pregnancy. II: correlation between oral hygiene and periodontal condtion. Acta Odontol Scand 1964;22:121-35.
19. Loe H. The gingival index, the plaque index and the retention index systems. J Periodontol 1967;38:Suppl:610-6.
20. Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J 1975;25:229-35.
21. de Almeida JM, Theodoro LH, Bosco AF, Nagata MJ, Bonfante S, Garcia VG. Treatment of experimental periodontal disease by photodynamic therapy in rats with diabetes. J Periodontol 2008;79: 2156-65.
22. Christodoulides N, Nikolidakis D, Chondros P, Becker J, Schwarz F, Rössler R, et al. Photodynamic therapy as an adjunct to non-surgical periodontal treatment: a randomized, controlled clinical trial. J Periodontol 2008;79:1638-44.
23. Polansky R, Haas M, Heschl A, Wimmer G. Clinical effectiveness of photodynamic therapy in the treatment of periodontitis. J Clin Periodontol 2009;36:575-80.
24. Theodoro LH, Silva SP, Pires JR, Soares GH, Pontes AE, Zuza EP, et al. Clinical and microbiological effects of photodynamic therapy associated with nonsurgical periodontal treatment. A 6-month follow-up. Lasers Med Sci 2012;27:687-93.
25. Pourabbas R, Kashefimehr A, Rahmanpour N, Babaloo Z, Kishen A, Tenenbaum HC, et al. Effects of photodynamic therapy on clinical and gingival crevicular fluid inflammatory biomarkers in chronic periodontitis: a split-mouth randomized clinical trial. J Periodontol 2014;85:1222-9.
26. Bassir SH, Moslemi N, Jamali R, Mashmouly S, Fekrazad R, Chiniforush N, et al. Photoactivated disinfection using light-emitting diode as an adjunct in the management of chronic periodontitis: a pilot double-blind split-mouth randomized clinical trial. J Clin Periodontol 2013;40:65-72.
27. Wainwright M. Photodynamic therapy: the development of new photosensitisers. Anticancer Agents Med Chem 2008;8:280-91.
28. Robinson DJ, de Bruijn HS, van der Veen N, Stringer MR, Brown SB, Star WM. Fluorescence photobleaching of ALA-induced protoporphyrin IX during photodynamic therapy of normal hairless mouse skin: the effect of light dose and irradiance and the resulting biological effect. Photochem Photobiol 1998;67:140-9.
29. Pfitzner A, Sigusch BW, Albrecht V, Glockmann E. Killing of periodontopathogenic bacteria by photodynamic therapy. J Periodontol 2004;75:1343-9.
30. Sorkhdini P, Moslemi N, Jamshidi S, Jamali R, Amirzargar AA, Fekrazad R. Effect of hydrosoluble chlorine-mediated antimicrobial photodynamic therapy on clinical parameters and cytokine profile in ligature-induced periodontitis in dogs. J Periodontol 2013; 84:793-800.
31. Nagahara A, Mitani A, Fukuda M, Yamamoto H, Tahara K, Morita I, et al. Antimicrobial photodynamic therapy using a diode laser with a potential new photosensitizer, indocyanine green-loaded nanospheres, may be effective for the clearance of Porphyromonas gingivalis. J Periodontal Res 2013;48:591-9.
32. Minnock A, Vernon DI, Schofield J, Griffiths J, Parish JH, Brown ST. Photoinactivation of bacteria. Use of a cationic water-soluble zinc phthalocyanine to photoinactivate both gram-negative and gram-positive bacteria. J Photochem Photobiol B 1996;32:159-64.
33. Soukos NS, Mulholland SE, Socransky SS, Doukas AG. Photodestruction of human dental plaque bacteria: enhancement of the photodynamic effect by photomechanical waves in an oral biofilm model. Lasers Surg Med 2003;33:161-8.
34. Komerik N, Wilson M, Poole S. The effect of photodynamic action on two virulence factors of gram-negative bacteria. Photochem Photobiol 2000;72:676-80.
35. Chui C, Aoki A, Takeuchi Y, Sasaki Y, Hiratsuka K, Abiko Y, et al. Antimicrobial effect of photodynamic therapy using high-power blue light-emitting diode and red-dye agent on Porphyromonas gingivalis. J Periodontal Res 2013;48:696-705.