Efficacy of antimicrobial photodynamic therapy in the management of chronic periodontitis: A randomized controlled clinical trial

Journal of Clinical Periodontology

Volumn 41, Issue 6, 2014, Pages 573-581

  Betsy, Joseph ^a   Prasanth, Chandra S ^b   Baiju, Kamalasanan V ^c   Prasanthila, Janam ^a   Subhash, Narayanan ^b,d  

^a GOVERNMENT DENTAL COLLEGE   (India)

^b CENTRE FOR EARTH SCIENCE STUDIES   (India)

^c Government College for Women   (India)

^d Vinvish Technologies Pvt Ltd   (India)

Author keywords

adjunctive periodontal treatment; halitosis; methylene blue; periodontal disease; photodynamic therapy; randomized controlled trial

Indexed keywords

METHYLENE BLUE; PHOTOSENSITIZING AGENT;

ADULT; CHRONIC PERIODONTITIS; COMPARATIVE STUDY; CONTROLLED STUDY; DIODE LASER; FEMALE; FOLLOW UP; GINGIVAL RECESSION; HALITOSIS; HUMAN; MALE; MULTIMODALITY CANCER THERAPY; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL POCKET; PERIODONTICS; PHOTOCHEMOTHERAPY; PREVENTIVE DENTISTRY; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; THERAPEUTIC USE; TOOTH PLAQUE;

ADULT; CHRONIC PERIODONTITIS; COMBINED MODALITY THERAPY; DENTAL PLAQUE INDEX; DENTAL SCALING; FEMALE; FOLLOW-UP STUDIES; GINGIVAL RECESSION; HALITOSIS; HUMANS; LASERS, SEMICONDUCTOR; MALE; METHYLENE BLUE; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL INDEX; PERIODONTAL POCKET; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; ROOT PLANING;

EID: 84900867850     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/jcpe.12249     Document Type: Article

References (37)

1. Adriaens, P. A., &, Adriaens, L. M., (2004) Effects of nonsurgical periodontal therapy on hard and soft tissues. Periodontology 2000 36, 121-145.
2. Ainamo, J., &, Bay, I., (1975) Problems and proposals for recording gingivitis and plaque. International Dental Journal 25, 229-235.
3. Alwaeli, H. A., Al-Khateeb, S. N., &, Al-Sadi, A., (2013) Long-term clinical effect of adjunctive antimicrobial photodynamic therapy in periodontal treatment: a randomized clinical trial. Lasers in Medical Science. doi: 10.1007/s10103-1426-y.
4. Andersen, R., Loebel, N., Hammond, D., &, Wilson, M., (2007) Treatment of periodontal disease by photo disinfection compared to scaling and root planing. The Journal of Clinical Dentistry 18, 34-38.
5. Arweiler, N. B., Pietruska, M., Skurska, A., Dolińska, E., Auschill, T. M., &, Sculean, A., (2013) Nonsurgical treatment of aggressive periodontitis with photodynamic therapy or systemic antibiotics. Schweizer Monatsschrift für Zahnmedizin 123, 532-544.
6. Atieh, M. A., (2010) Photodynamic therapy as an adjunctive treatment for chronic periodontitis: meta-analysis. Lasers in Medical Science 25, 605-613.
7. Azarpazhooh, A., Prakesh, S., Tenenbaum, H., &, Goldberg, M., (2010) The effect of photodynamic therapy for periodontitis: a systematic review and meta-analysis. Journal of Periodontology 81, 4-14.
8. Balata, M. L., de Andrade, L. P., Santos, D. B., Cavalcanti, A. N., Ribeiro, E. D., &, Bittencourt, S., (2013) Photodynamic therapy associated with full-mouth ultrasonic debridement in the treatment of severe chronic periodontitis: randomized-controlled clinical trial. Journal of Applied Oral Science 21, 208-214.
9. Braham, P., Herron, C., Street, C., &, Darveau, R., (2009) Antimicrobial photodynamic therapy may promote periodontal healing through multiple mechanisms. Journal of Periodontology 80, 1790-1798.
10. Berakdar, M., Callaway, A., Eddin, M. F., Ross, A., &, Willershausen, B., (2012) Comparison between scaling-root-planing (SRP) and SRP/photodynamic therapy: six-month study. Head & Face Medicine 8, 12.
11. Braun, A., Dehn, C., Krause, F., &, Jepsen, S., (2008) Short-term clinical effects of adjunctive antimicrobial photodynamic therapy in periodontal treatment: a randomized clinical trial. Journal of Clinical Periodontology 35, 877-884.
12. Campanile, V. S. M., Giannopoulou, C., Campanile, G., José, A., &, Mombelli, A., (2013) A Single or repeated antimicrobial photodynamic therapy as adjunct to ultrasonic debridement in residual periodontal pockets: clinical, microbiological, and local biological effects. Lasers in Medical Science. doi: 10.1007/s10103-013-1337-y.
13. Campos, G. N., Pimentel, S. P., Ribeiro, F. V., Casarin, R. C. V., Fabiano, C. R., &, Márcio, C. Z., (2013) The adjunctive effect of photodynamic therapy for residual pockets in single-rooted teeth: a randomized controlled clinical trial. Lasers in Medical Science 28, 317-324.
14. Christodoulides, N., Nikolidakis, D., &, Chondros, P., (2008) Photodynamic therapy as an adjunct to non-surgical periodontal treatment: a randomized, controlled clinical trial. Journal of Periodontology 79, 1638-1644.
15. Fernando, O. C., Alessandra, N. G., Luís, O. M. C., André, L. P., Takeshi, K. S., Sheila, C. C., &, José, E. C., (2009) Impact of different periodontitis case definitions on periodontal research. Journal of Oral Science 51, 199-206.
16. Ge, L., Shu, R., Li, Y., Li, C., Luo, L., Song, Z., Xie, Y., &, Liu, D., (2011) Adjunctive effect of photodynamic therapy to scaling and root planing in the treatment of chronic periodontitis. Photomedicine and Laser Surgery 29, 33-37.
17. Herrera, D., Sanz, M., Jepsen, S., Needleman, I., &, Roldan, S., (2002) A systematic review on the effect of systemic antimicrobials as an adjunct to scaling and root planing in periodontitis patients. Journal of Clinical Periodontology 29 (Suppl. 3), 136-159.
18. Katie, O., Akilov, O. E., &, Hasan, T., (2005) The potential for photodynamic therapy in the treatment of localized infections. Photodiagnosis and Photodynamic Therapy 2, 247-262.
19. Komerik, N., Nakanishi, H., MacRobert, A. J., Henderson, B., Speight, P., &, Wilson, M., (2003) In vivo killing of Porphyromonas gingivalis by toluidine blue-mediated photosensitization in an animal model. Antimicrobial Agents and Chemotherapy 47, 932-940.
20. Lawson, A., (1983) Rank analysis of covariance: alternative approaches. Journal of the Royal Statistical Society. Series D (The Statistician) 32, 331-337.
21. Löe, H., (1967) The gingival index, the plaque index and the retention index systems. Journal of Periodontology 38, 610-616. (Supplement).
22. Malik, Z., Hanania, J., &, Nitzan, Y., (1990) Bactericidal effects of photoactivated porphyrins-an alternative approach to antimicrobial drugs. Journal of Photochemistry and Photobiology. B, Biology 5, 281-293.
23. Noro Filho, G. A., Casarin, R. C., Casati, M. Z., &, Giovani, E. M., (2012) PDT in non-surgical treatment of periodontitis in HIV patients: a split-mouth, randomized clinical trial. Lasers in Surgery and Medicine 44, 296-302.
24. Novaes, A. B. Jr, Schwartz-Filho, H. O., de Oliveira, R. R., Feres, M., Sato, S., &, Figueiredo, L. C., (2012) Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: microbiological profile. Lasers in Medical Science 27, 389-395.
25. de Oliveira, R. R., Schwartz-Filho, H., &, Novaes, A. Jr, (2009) Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: cytokine profile in gingival crevicular fluid, preliminary results. Journal of Periodontology 80, 98-105.
26. de Oliveira, R. R., Schwartz-Filho, H. O., Novaes, A. B. Jr, &, Taba, M. Jr, (2007) Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: a preliminary randomized controlled clinical study. Journal of Periodontology 78, 965-973.
27. Pfitzner, A., Sigush, B. W., Albrecht, V., &, Glockmann, E., (2004) Killing of periodonto-pathogenic bacteria by photodynamic therapy. Journal of Periodontology 75, 1343-1349.
28. Pinheiro, S. L., Donegá, J. M., Seabra, L. M. S., Adabo, M. D., Lopes, T., do Carmo, T. H. D., Riberio, M. C., &, Bertolini, P. F. R., (2010) Capacity of photodynamic therapy for microbial reduction in periodontal pockets. Lasers in Medical Science 25, 87-91.
29. Puri, M. L., &, Sen, P. K., (1969) Analysis of covariance based on general rank scores. Annals of Mathematical Statistics 40, 610-618.
30. Quade, D., (1967) Rank analysis of covariance. Journal of the American Statistical Association 62, 1187-1200.
31. Schneider, M., Kirfel, G., Berthold, M., Frentzen, M., Krause, F., &, Braun, A., (2012) The impact of antimicrobial photodynamic therapy in an artificial biofilm model. Lasers in Medical Science 27, 615-620.
32. Sgolastra, F., Petrucci, A., Gatto, R., Marzo, G., &, Monaco, A., (2013) Photodynamic therapy in the treatment of chronic periodontitis: a systematic review and meta-analysis. Lasers in Medical Science 28, 669-682.
33. Silness, J., &, Loe, H., (1964) Periodontal disease in pregnancy II. Correlation between oral hygiene and periodontal condition. Acta Odontologica Scandinavica 22, 112-135.
34. Song, H. H., Lee, J. K., Um, H. S., Chang, B. S., Lee, S. Y., &, Lee, M. K., (2013) Phototoxic effect of blue light on the planktonic and biofilm state of anaerobic periodontal pathogens. Journal of Periodontal & Implant Science 43, 72-78.
35. Umeda, M., Takeuchi, Y., Noguchi, K., Huang, Y., Koshy, G., &, Ishikawa, I., (2004) Effects of nonsurgical periodontal therapy on the microbiota. Periodontology 2000 36, 98-120.
36. Wilson, M., (2004) Lethal photosensitisation of oral bacteria and its potential application in the photodynamic therapy of oral infections. Photochemical and Photobiological Sciences 3, 412-418.
37. Yilmaz, S., Kuru, B., Kuru, L., Noyan, U., Argun, D., &, Kadir, T., (2002) Effect of gallium arsenide diode laser on human periodontal disease: a microbiological and clinical study. Lasers in Surgery and Medicine 30, 60-66.