The development of cognitive control in children with chromosome 22q11.2 deletion syndrome

Frontiers in Psychology

Volumn 5, Issue JUN, 2014, Pages

  Shapiro, Heather M ^a   Tassone, Flora ^a,b   Choudhary, Nimrah S ^b   Simon, Tony J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

22q11.2 deletion syndrome; Catechol O methyltransferase (COMT); Childhood cognitive development; Cognitive control; Developmental disorders; Executive function

Indexed keywords

EID: 84920535522     PISSN: None     EISSN: 16641078     Source Type: Journal    
DOI: 10.3389/fpsyg.2014.00566     Document Type: Article

References (68)

1. Alexander, G. E., DeLong, M. R., and Strick, P. L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu. Rev. Neurosci. 9, 357-381. doi: 10.1146/annurev.ne.09.030186.002041
2. Angkustsiri, K., Leckliter, I., Tartaglia, N., Beaton, E. A., Enriquez, J., and Simon, T. J. (2012). An examination of the relationship of anxiety and intelligence to adaptive functioning in children with chromosome 22q11.2 deletion syndrome. J. Dev. Behav. Pediatr. 33, 713-720. doi: 10.1097/DBP.0b013e3182 72dd24
3. Baker, K., Baldeweg, T., Sivagnanasundaram, S., Scambler, P., and Skuse, D. (2005). COMT Val108/158 Met modifies mismatch negativity and cognitive function in 22q11 deletion syndrome. Biol. Psychiatry 58, 23-31. doi: 10.1016/j.biopsych.2005.03.020
4. Bassett, A. S., Chow, E. W. C., AbdelMalik, P., Gheorghiu, M., Husted, J., and Weksberg, R. (2003). The schizophrenia phenotype in 22q11 deletion syndrome. Am. J. Psychiatry 160, 1580-1586. doi: 10.1176/appi.ajp.160.9.1580
5. Bearden, C. E., Jawad, A. F., Lynch, D. R., Sokol, S., Kanes, S. J., McDonald-McGinn, D. M., et al. (2004). Effects of a functional COMT polymorphism on prefrontal cognitive function in patients with 22q11.2 deletion syndrome. Am. J. Psychiatry 161, 1700-1702. doi: 10.1176/appi.ajp.161.9.1700
6. Bearden, C. E., van Erp, T. G. M., Dutton, R. A., Lee, A. D., Simon, T. J., Cannon, T. D., et al. (2009). Alterations in midline cortical thickness and gyrification patterns mapped in children with 22q11.2 deletions. Cereb. Cortex 19, 115-126. doi: 10.1093/cercor/bhn064
7. Beaton, E. A., and Simon, T. J. (2011). How might stress contribute to increased risk for schizophrenia in children with chromosome 22q11.2 deletion syndrome? J. Neurodev. Disord. 3, 68-75. doi: 10.1007/s11689-010-9069-9
8. Berman, K. F., Ostrem, J. L., Randolph, C., Gold, J., Goldberg, T. E., Coppola, R., et al. (1995). Physiological activation of a cortical network during performance of the Wisconsin Card Sorting Test: a positron emission tomography study. Neuropsychologia 33, 1027-1046. doi: 10.1016/0028-3932(95)00035-2
9. Best, J. R., and Miller, P. H. (2010). A developmental perspective on executive function. Child Dev. 81, 1641-1660. doi: 10.1111/j.1467-8624.2010.01499.x
10. Bish, J. P., Ferrante, S. M., McDonald-McGinn, D., Zackai, E., and Simon, T. J. (2005). Maladaptive conflict monitoring as evidence for executive dysfunction in children with chromosome 22q11.2 deletion syndrome. Dev. Sci. 8, 36-43. doi: 10.1111/j.1467-7687.2005.00391.x
11. Brewer, W. J., Francey, S. M., Wood, S. J., Jackson, H. J., Pantelis, C., Phillips, L. J., et al. (2005). Memory impairments identified in people at ultra-high risk for psychosis who later develop first-episode psychosis. Am. J. Psychiatry 162, 71-78. doi: 10.1176/appi.ajp.162.1.71
12. Campbell, L. E., Azuma, R., Ambery, F., Stevens, A., Smith, A., Morris, R. G., et al. (2010). Executive functions and memory abilities in children with 22q11.2 deletion syndrome. Aust. N. Z. J. Psychiatry 44, 364-371. doi: 10.3109/00048670903489882
13. Cannon, T. D., van Erp, T. G. M., Bearden, C. E., Loewy, R., Thompson, P., Toga, A. W., et al. (2003). Early and late neurodevelopmental influences in the prodrome to schizophrenia: contributions of genes, environment, and their interactions. Schizophr. Bull. 29, 653-669. doi: 10.1093/oxfordjournals.schbul.a007037
14. Carlson, C., Sirotkin, H., Pandita, R., Goldberg, R., McKie, J., Wadey, R., et al. (1997). Molecular definition of 22q11 deletions in 151 velo-cardio-facial syndrome patients. Am. J. Hum. Genet. 61, 620-629. doi: 10.1086/515508
15. Carter, C. S., and Barch, D. M. (2007). Cognitive neuroscience-based approaches to measuring and improving treatment effects on cognition in schizophrenia: the CNTRICS initiative. Schizophr. Bull. 33, 1131-1137. doi: 10.1093/schbul/sbm081
16. Casey, B. J., Trainor, R. J., Orendi, J. L., Schubert, A. B., Nystrom, L. E., Giedd, J. N., et al. (1997). A developmental functional MRI study of prefrontal activation during performance of a Go-No-Go task. J. Cogn. Neurosci. 9, 835-847. doi: 10.1162/jocn.1997.9.6.835
17. Collins, P., Roberts, A. C., Dias, R., Everitt, B. J., and Robbins, T. W. (1998). Perseveration and strategy in a novel spatial self-ordered sequencing task for nonhuman primates: effects of excitotoxic lesions and dopamine depletions of the prefrontal cortex. J. Cogn. Neurosci. 10, 332-354. doi: 10.1162/089892998562771
18. Dennis, M., Francis, D. J., Cirino, P. T., Schachar, R., Barnes, M. A., and Fletcher, J. M. (2009). Why IQ is not a covariate in cognitive studies of neurodevelopmental disorders. J. Int. Neuropsychol. Soc. 15, 331-343. doi: 10.1017/S1355617709090481
19. Diamond, A., Prevor, M. B., Callender, G., and Druin, D. P. (1997). Prefrontal cortex cognitive deficits in children treated early and continuously for PKU. Monogr. Soc. Res. Child Dev. 62, i-v, 1-208. doi: 10.2307/1166208
20. Dias, R., Robbins, T. W., and Roberts, A. C. (1996). Primate analogue of the Wisconsin Card Sorting Test: effects of excitotoxic lesions of the prefrontal cortex in the marmoset. Behav. Neurosci. 110, 872-886. doi: 10.1037/0735- 7044.110.5.872
21. Duncan, J., Burgess, P., and Emslie, H. (1995). Fluid intelligence after frontal lobe lesions. Neuropsychologia 33, 261-268. doi: 10.1016/0028-3932(94)00124-8
22. Eliez, S., Barnea-Goraly, N., Schmitt, J. E., Liu, Y., and Reiss, A. L. (2002). Increased basal ganglia volumes in velo-cardio-facial syndrome (deletion 22q11.2). Biol. Psychiatry 52, 68-70. doi: 10.1016/S0006-3223(02)01361-6
23. Friedman, N. P., and Miyake, A. (2004). The relations among inhibition and interference control functions: a latent-variable analysis. J. Exp. Psychol. Gen. 133, 101-135. doi: 10.1037/0096-3445.133.1.101
24. Friedman, N. P., Miyake, A., Corley, R. P., Young, S. E., Defries, J. C., and Hewitt, J. K. (2006). Not all executive functions are related to intelligence. Psychol. Sci. 17, 172-179. doi: 10.1111/j.1467-9280.2006.01681.x
25. Glaser, B., Debbané, M., Hinard, C., Morris, M. A., Dahoun, S. P., Antonarakis, S. E., et al. (2006). No evidence for an effect of COMT Val158Met genotype on executive function in patients with 22q11 deletion syndrome. Am. J. Psychiatry 163, 537-539. doi: 10.1176/appi.ajp.163.3.537
26. Gothelf, D., Hoeft, F., Hinard, C., Hallmayer, J. F., Stoecker, J. V. D., Antonarakis, S. E., et al. (2007a). Abnormal cortical activation during response inhibition in 22q11.2 deletion syndrome. Hum. Brain Mapp. 28, 533-542. doi: 10.1002/hbm.20405
27. Gothelf, D., Penniman, L., Gu, E., Eliez, S., and Reiss, A. L. (2007b). Developmental trajectories of brain structure in adolescents with 22q11.2 deletion syndrome: a longitudinal study. Schizophr. Res. 96, 72-81. doi: 10.1016/j.schres.2007. 07.021
28. Huizinga, M., Dolan, C. V., and van der Molen, M. W. (2006). Age-related change in executive function: developmental trends and a latent variable analysis. Neuropsychologia 44, 2017-2036. doi: 10.1016/j.neuropsychologia.2006.01.010
29. Iversen, S. D., and Mishkin, M. (1970). Perseverative interference in monkeys following selective lesions of the inferior prefrontal convexity. Exp. Brain Res. 11, 376-386. doi: 10.1007/BF00237911
30. Kates, W. R., Antshel, K. M., Abdulsabur, N., Colgan, D., Funke, B., Fremont, W., et al. (2006). A gender-moderated effect of a functional COMT polymorphism on prefrontal brain morphology and function in velo-cardio-facial syndrome (22q11.2 deletion syndrome). Am. J. Med. Genet. B Neuropsychiatr. Genet. 141B, 274-280. doi: 10.1002/ajmg.b.30284
31. Kates, W. R., Antshel, K. M., Faraone, S. V., Fremont, W. P., Higgins, A. M., Shprintzen, R. J., et al. (2011). Neuroanatomic predictors to prodromal psychosis in velocardiofacial syndrome (22q11.2 deletion syndrome): a longitudinal study. Biol. Psychiatry 69, 945-952. doi: 10.1016/j.biopsych.2010.10.027
32. Kates, W. R., Krauss, B. R., Abdulsabur, N., Colgan, D., Antshel, K. M., Higgins, A. M., et al. (2007). The neural correlates of non-spatial working memory in velocardiofacial syndrome (22q11.2 deletion syndrome). Neuropsychologia 45, 2863-2873. doi: 10.1016/j.neuropsychologia.2007.05.007
33. Kimberg, D. Y., and D'Esposito, M. (2003). Cognitive effects of the dopamine receptor agonist pergolide. Neuropsychologia 41, 1020-1027. doi: 10.1016/S0028- 3932(02)00317-2
34. Kunwar, A., Ramanathan, S., Nelson, J., Antshel, K. M., Fremont, W., Higgins, A. M., et al. (2012). Cortical gyrification in velo-cardio-facial (22q11.2 deletion) syndrome: a longitudinal study. Schizophr. Res. 137, 20-25. doi: 10.1016/j.schres.2012.01.032
35. Lencz, T., Smith, C. W., McLaughlin, D., Auther, A., Nakayama, E., Hovey, L., et al. (2006). Generalized and specific neurocognitive deficits in prodromal schizophrenia. Biol. Psychiatry 59, 863-871. doi: 10.1016/j.biopsych.2005.09.005
36. Lewandowski, K. E., Shashi, V., Berry, P. M., and Kwapil, T. R. (2007). Schizophrenic-like neurocognitive deficits in children and adolescents with 22q11 deletion syndrome. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B, 27-36. doi: 10.1002/ajmg.b.30379
37. Miyake, A., and Friedman, N. P. (2012). The nature and organization of individual differences in executive functions: four general conclusions. Curr. Dir. Psychol. Sci. 21, 8-14. doi: 10.1177/0963721411429458
38. Miyake, A., Friedman, N. P., Emerson, M. J., Witzki, A. H., Howerter, A., and Wager, T. D. (2000). The unity and diversity of executive functions and their contributions to complex "Frontal Lobe" tasks: a latent variable analysis. Cogn. Psychol. 41, 49-100. doi: 10.1006/cogp.1999.0734
39. Murphy, K. C., Jones, L. A., and Owen, M. J. (1999). High rates of schizophrenia in adults with velo-cardio-facial syndrome. Arch. Gen. Psychiatry 56, 940-945. doi: 10.1001/archpsyc.56.10.940
40. Oskarsdóttir, S., Vujic, M., and Fasth, A. (2004). Incidence and prevalence of the 22q11 deletion syndrome: a population-based study in Western Sweden. Arch. Dis. Child. 89, 148-151. doi: 10.1136/adc.2003.026880
41. Passingham, R. E. (1972). Non-reversal shifts after selective prefrontal ablations in monkeys (Macaca mulatta). Neuropsychologia 10, 41-46. doi: 10.1016/0028- 3932(72)90041-3
42. Petrides, M. (1991). Functional specialization within the dorsolateral frontal cortex for serial order memory. Proc. Biol. Sci. 246, 299-306. doi: 10.1098/rspb.1991.0158
43. Petrides, M., Alivisatos, B., Evans, A. C., and Meyer, E. (1993). Dissociation of human mid-dorsolateral from posterior dorsolateral frontal cortex in memory processing. Proc. Natl. Acad. Sci. U.S.A. 90, 873-877. doi: 10.1073/pnas.90.3.873
44. Petrides, M., and Milner, B. (1982). Deficits on subject-ordered tasks after frontal- and temporal-lobe lesions in man. Neuropsychologia 20, 249-262. doi: 10.1016/0028-3932(82)90100-2
45. Roca, M., Parr, A., Thompson, R., Woolgar, A., Torralva, T., Antoun, N., et al. (2010). Executive function and fluid intelligence after frontal lobe lesions. Brain 133, 234-247. doi: 10.1093/brain/awp269
46. Scambler, P. J. (2000). The 22q11 deletion syndromes. Hum. Mol. Genet. 9, 2421-2426. doi: 10.1093/hmg/9.16.2421
47. Schaer, M., Debbané, M., Bach Cuadra, M., Ottet, M.-C., Glaser, B., Thiran, J.- P., et al. (2009). Deviant trajectories of cortical maturation in 22q11.2 deletion syndrome (22q11DS): a cross-sectional and longitudinal study. Schizophr. Res. 115, 182-190. doi: 10.1016/j.schres.2009.09.016
48. Shapiro, H. M., Takarae, Y., Harvey, D., Cabaral, M., and Simon, T. J. (2012). A cross-sectional study of the development of volitional control of spatial attention in children with chromosome 22q11.2 deletion syndrome. J. Neurodev. Disord. 4:5. doi: 10.1186/1866-1955-4-5
49. Shapiro, H. M., Wong, L. M., and Simon, T. J. (2013). A cross-sectional analysis of the development of response inhibition in children with chromosome 22q11.2 deletion syndrome. Front. Psychiatry 4:81. doi: 10.3389/fpsyt.2013.00081
50. Shashi, V., Keshavan, M. S., Howard, T. D., Berry, M. N., Basehore, M. J., Lewandowski, E., et al. (2006). Cognitive correlates of a functional COMT polymorphism in children with 22q11.2 deletion syndrome. Clin. Genet. 69, 234-238. doi: 10.1111/j.1399-0004.2006.00569.x
51. Shashi, V., Kwapil, T. R., Kaczorowski, J., Berry, M. N., Santos, C. S., Howard, T. D., et al. (2010). Evidence of gray matter reduction and dysfunction in chromosome 22q11.2 deletion syndrome. Psychiatry Res. 181, 1-8. doi: 10.1016/j.pscychresns.2009.07.003
52. Shaw, P., Gogtay, N., and Rapoport, J. (2010). Childhood psychiatric disorders as anomalies in neurodevelopmental trajectories. Hum. Brain Mapp. 31, 917-925. doi: 10.1002/hbm.21028
53. Shprintzen, R. J. (2008). Velo-cardio-facial syndrome: 30 Years of study. Dev. Disabil. Res. Rev. 14, 3-10. doi: 10.1002/ddrr.2
54. Simon, T. J. (2008). A new account of the neurocognitive foundations of impairments in space, time and number processing in children with chromosome 22q11.2 deletion syndrome. Dev. Disabil. Res. Rev. 14, 52-58. doi: 10.1002/ddrr.8
55. Simon, T. J., Bish, J. P., Bearden, C. E., Ding, L., Ferrante, S., Nguyen, V., et al. (2005). A multilevel analysis of cognitive dysfunction and psychopathology associated with chromosome 22q11.2 deletion syndrome in children. Dev. Psychopathol. 17, 753-784. doi: 10.1017/S0954579405050364
56. Simon, T. J., and Luck, S. J. (2011). Attentional Impairments in Children with Chromosome 22q11.2 Deletion Syndrome, 2nd Edn. New York, NY: Guilford Press.
57. Simon, T. J., Wu, Z., Avants, B., Zhang, H., Gee, J. C., and Stebbins, G. T. (2008). Atypical cortical connectivity and visuospatial cognitive impairments are related in children with chromosome 22q11.2 deletion syndrome. Behav. Brain Funct. 4:25. doi: 10.1186/1744-9081-4-25
58. Snitz, B. E., MacDonald, A. W., and Carter, C. S. (2006). Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of putative endophenotypes. Schizophr. Bull. 32, 179-194. doi: 10.1093/schbul/sbi048
59. Sobin, C., Kiley-Brabeck, K., and Karayiorgou, M. (2005). Lower prepulse inhibition in children with the 22q11 deletion syndrome. Am. J. Psychiatry 162, 1090-1099. doi: 10.1176/appi.ajp.162.6.1090
60. Srivastava, S., Buonocore, M. H., and Simon, T. J. (2011). Atypical developmental trajectory of functionally significant cortical areas in children with chromosome 22q11.2 deletion syndrome. Hum. Brain Mapp. 33, 213-223. doi: 10.1002/hbm.21206
61. Stoddard, J., Beckett, L., and Simon, T. J. (2011). Atypical development of the executive attention network in children with chromosome 22q11.2 deletion syndrome. J. Neurodev. Disord. 3, 76-85. doi: 10.1007/s11689-010-9070-3
62. Stroop, J. R. (1935). Studies of interference in serial verbal reactions. J. Exp. Psychol. Gen. 6, 643-666. doi: 10.1037/h0054651
63. Sugama, S., Bingham, P. M., Wang, P. P., Moss, E. M., Kobayashi, H., and Eto, Y. (2000). Morphometry of the head of the caudate nucleus in patients with velocardiofacial syndrome (del 22q11.2). Acta Paediatr. 89, 546-549. doi: 10.1080/080352500750027826
64. Takarae, Y., Schmidt, L., Tassone, F., and Simon, T. J. (2009). Catechol-Omethyltransferase polymorphism modulates cognitive control in children with chromosome 22q11.2 deletion syndrome. Cogn. Affect. Behav. Neurosci. 9, 83-90. doi: 10.3758/CABN.9.1.83
65. Vorstman, J. A. S., Turetsky, B. I., Sijmens-Morcus, M. E. J., de Sain, M. G., Dorland, B., Sprong, M., et al. (2009). Proline affects brain function in 22q11DS children with the low activity COMT 158 allele. Neuropsychopharmacology 34, 739-746. doi: 10.1038/npp.2008.132
66. Wechsler, D. (1999). Wechsler Abbreviated Scale of Intelligence (WASI). San Antonio, TX: Psychological Corp.
67. Wechsler, D. (2003). WISC-IV Technical and Interpretive Manual. San Antonio, TX: Psychological Corp.
68. Zelazo, P. D., Craik, F. I. M., and Booth, L. (2004). Executive function across the life span. Acta Psychol. 115, 167-183. doi: 10.1016/j.actpsy.2003. 12.005