Proline affects brain function in 22q11DS children with the low activity COMT158 allele

Neuropsychopharmacology

Volumn 34, Issue 3, 2009, Pages 739-746

  Vorstman, Jacob A S ^a,b   Turetsky, Bruce I ^c   Sijmens Morcus, Monique E J ^a   De Sain, Monique G ^d   Dorland, Bert ^d   Sprong, Mirjam ^a   Rappaport, Eric F ^b   Beemer, Frits A ^d   Emanuel, Beverly S ^b,c   Kahn, René S ^a   Van Engeland, Herman ^a   Kemner, Chantal ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

22q11.2DS; Catechol O methyl transferase; Endophenotype; Prepulse inhibition; Proline; Smooth pursuit

Indexed keywords

CATECHOL METHYLTRANSFERASE; DOPAMINE; PROLINE; PROLINE DEHYDROGENASE;

ADOLESCENT; ADULT; ALLELE; ARTICLE; AUDITORY STIMULATION; BRAIN DYSFUNCTION; BRAIN FUNCTION; CHILD; CHROMOSOME 22Q; CHROMOSOME DELETION; COMT GENE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOPAMINE METABOLISM; EVOKED AUDITORY RESPONSE; FEMALE; FRONTAL CORTEX; GENE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; PREPULSE INHIBITION; PRIORITY JOURNAL; PRODH GENE; SCHOOL CHILD; SMOOTH PURSUIT EYE MOVEMENT; STARTLE REFLEX;

ADOLESCENT; ALLELES; CATECHOL O-METHYLTRANSFERASE; CHILD; DIGEORGE SYNDROME; DOPAMINE; ELECTROENCEPHALOGRAPHY; FEMALE; GENOTYPE; HUMANS; MALE; OCULAR MOTILITY DISORDERS; PREFRONTAL CORTEX; PROLINE; PROLINE OXIDASE; SENSORY GATING; STARTLE REACTION;

EID: 58149459988     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2008.132     Document Type: Article

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