-
1
-
-
0030696675
-
The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC
-
Berglund JA, Chua K, Abovich N, Reed R, Rosbash M. 1997. The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC. Cell 89: 781–787.
-
(1997)
Cell
, vol.89
, pp. 781-787
-
-
Berglund, J.A.1
Chua, K.2
Abovich, N.3
Reed, R.4
Rosbash, M.5
-
2
-
-
0032521186
-
A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition
-
Berglund JA, Abovich N, Rosbash M. 1998. A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition. Genes Dev 13: 858–867.
-
(1998)
Genes Dev
, vol.13
, pp. 858-867
-
-
Berglund, J.A.1
Abovich, N.2
Rosbash, M.3
-
3
-
-
0036948420
-
Allosteric cascade of spliceosome activation
-
Brow DA. 2002. Allosteric cascade of spliceosome activation. Annu Rev Genet 36: 333–360.
-
(2002)
Annu Rev Genet
, vol.36
, pp. 333-360
-
-
Brow, D.A.1
-
4
-
-
0027287852
-
A mechanism to enhance mRNA splicing fidelity: The RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates
-
Burgess SM, Guthrie C. 1993a. A mechanism to enhance mRNA splicing fidelity: the RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates. Cell 73: 1377–1392.
-
(1993)
Cell
, vol.73
, pp. 1377-1392
-
-
Burgess, S.M.1
Guthrie, C.2
-
5
-
-
0027361712
-
Beat the clock: Paradigms for NTPases in the maintenance of biological fidelity
-
Burgess SM, Guthrie C. 1993b. Beat the clock: paradigms for NTPases in the maintenance of biological fidelity. Trends Biochem Sci 18: 381–384.
-
(1993)
Trends Biochem Sci
, vol.18
, pp. 381-384
-
-
Burgess, S.M.1
Guthrie, C.2
-
6
-
-
0025233806
-
A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing
-
Burgess S, Couto JR, Guthrie C. 1990. A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing. Cell 60: 705–717.
-
(1990)
Cell
, vol.60
, pp. 705-717
-
-
Burgess, S.1
Couto, J.R.2
Guthrie, C.3
-
7
-
-
24744465409
-
The Prp19-associated complex is required for specifying interactions of U5 and U6 with PremRNA during spliceosome activation
-
Chan S-P, Cheng S-C. 2005. The Prp19-associated complex is required for specifying interactions of U5 and U6 with PremRNA during spliceosome activation. J Biol Chem 280: 31190–31199.
-
(2005)
J Biol Chem
, vol.280
, pp. 31190-31199
-
-
Chan, S.-P.1
Cheng, S.-C.2
-
8
-
-
0141924550
-
The Prp19passociated complex in spliceosome activation
-
Chan S-P, Kao D-I, Tsai W-Y, Cheng S-C. 2003. The Prp19passociated complex in spliceosome activation. Science 302: 279–282.
-
(2003)
Science
, vol.302
, pp. 279-282
-
-
Chan, S.-P.1
Kao, D.-I.2
Tsai, W.-Y.3
Cheng, S.-C.4
-
9
-
-
0023449728
-
Spliceosome assembly in yeast
-
Cheng S-C, Abelson J. 1987. Spliceosome assembly in yeast. Genes Dev 1: 1014–1027.
-
(1987)
Genes Dev
, vol.1
, pp. 1014-1027
-
-
Cheng, S.-C.1
Abelson, J.2
-
10
-
-
0025375233
-
Preparation and fractionation of yeast splicing extract
-
Cheng S-C, Newman A, Lin R-J, McFarland GD, Abelson JN. 1990. Preparation and fractionation of yeast splicing extract. Methods Enzymol 181: 89–96.
-
(1990)
Methods Enzymol
, vol.181
, pp. 89-96
-
-
Cheng, S.-C.1
Newman, A.2
Lin, R.-J.3
McFarland, G.D.4
Abelson, J.N.5
-
11
-
-
84876441548
-
A weak spliceosome-binding domain of Yju2 functions in first step and bypasses Prp16 in second step of splicing
-
Chiang T-W, Cheng S-C. 2013. A weak spliceosome-binding domain of Yju2 functions in first step and bypasses Prp16 in second step of splicing. Mol Cell Biol 33: 1746–1755.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 1746-1755
-
-
Chiang, T.-W.1
Cheng, S.-C.2
-
12
-
-
70449625597
-
The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome
-
Fabrizio P, Dannenberg J, Dube P, Kastner B, Stark H, Urlaub H, Luhrmann R. 2009. The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell 36: 593–608.
-
(2009)
Mol Cell
, vol.36
, pp. 593-608
-
-
Fabrizio, P.1
Dannenberg, J.2
Dube, P.3
Kastner, B.4
Stark, H.5
Urlaub, H.6
Luhrmann, R.7
-
13
-
-
0031878108
-
A potential role for U2AF SAP155 interactions in recruiting U2 snRNP to the branch site
-
Gozani O, Potashkin J, Reed R. 1998. A potential role for U2AF SAP155 interactions in recruiting U2 snRNP to the branch site. Mol Cell Biol 18: 4752–4760.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4752-4760
-
-
Gozani, O.1
Potashkin, J.2
Reed, R.3
-
14
-
-
34147179830
-
U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicing
-
Hilliker AK, Mefford MA, Staley JP. 2007. U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicing. Genes Dev 21: 821–834.
-
(2007)
Genes Dev
, vol.21
, pp. 821-834
-
-
Hilliker, A.K.1
Mefford, M.A.2
Staley, J.P.3
-
15
-
-
84891417744
-
Sad1 counteracts Brr2-mediated dissociation of U4/U6.U5 in tri-snRNP homeostasis
-
Huang Y-H, Chung C-S, Kao D-I, Kao T-C, Cheng S-C. 2014. Sad1 counteracts Brr2-mediated dissociation of U4/U6.U5 in tri-snRNP homeostasis. Mol Cell Biol 34: 210–220.
-
(2014)
Mol Cell Biol
, vol.34
, pp. 210-220
-
-
Huang, Y.-H.1
Chung, C.-S.2
Kao, D.-I.3
Kao, T.-C.4
Cheng, S.-C.5
-
16
-
-
0035177309
-
Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomal ATPase
-
Kistler AL, Guthrie C. 2001. Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomal ATPase. Genes Dev 15: 42–49.
-
(2001)
Genes Dev
, vol.15
, pp. 42-49
-
-
Kistler, A.L.1
Guthrie, C.2
-
17
-
-
77955488349
-
The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 59 splice site cleavage during pre-mRNA splicing
-
Koodathingal P, Novak T, Piccirilli JA, Staley JP. 2010. The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 59 splice site cleavage during pre-mRNA splicing. Mol Cell 39: 385–395.
-
(2010)
Mol Cell
, vol.39
, pp. 385-395
-
-
Koodathingal, P.1
Novak, T.2
Piccirilli, J.A.3
Staley, J.P.4
-
18
-
-
67649337263
-
DExD/H-box Prp5 protein is in the spliceosome during most of the splicing cycle
-
Kosowski TR, Keys HR, Quan TK, Ruby SW. 2009. DExD/H-box Prp5 protein is in the spliceosome during most of the splicing cycle. RNA 15: 1345–1362.
-
(2009)
RNA
, vol.15
, pp. 1345-1362
-
-
Kosowski, T.R.1
Keys, H.R.2
Quan, T.K.3
Ruby, S.W.4
-
20
-
-
33744937919
-
Exon ligation is proofread by the DExD/H-box ATPase Prp22p
-
Mayas RM, Maita H, Staley JP. 2006. Exon ligation is proofread by the DExD/H-box ATPase Prp22p. Nat Struct Mol Biol 13: 482–490.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 482-490
-
-
Mayas, R.M.1
Maita, H.2
Staley, J.P.3
-
21
-
-
0037980050
-
Spatial organization of protein–RNA interactions in the branch site–39 splice site region during pre-mRNA splicing in yeast
-
McPheeters DS, Muhlenkamp P. 2003. Spatial organization of protein–RNA interactions in the branch site–39 splice site region during pre-mRNA splicing in yeast. Mol Cell Biol 23: 4174–4186.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4174-4186
-
-
McPheeters, D.S.1
Muhlenkamp, P.2
-
22
-
-
0030475009
-
The Saccharomyces cerevisiae Prp5 protein has RNA-dependent ATPase activity with specificity for U2 small nuclear RNA
-
O’Day CL, Dalbadie-McFarland G, Abelson J. 1996. The Saccharomyces cerevisiae Prp5 protein has RNA-dependent ATPase activity with specificity for U2 small nuclear RNA. J Biol Chem 271: 33261–33267.
-
(1996)
J Biol Chem
, vol.271
, pp. 33261-33267
-
-
O’Day, C.L.1
Dalbadie-McFarland, G.2
Abelson, J.3
-
23
-
-
0023663370
-
Recognition of the TACTAAC box during mRNA splicing in yeast involves base-pairing to the U2-like snRNA
-
Parker R, Siliciano P, Guthrie C. 1987. Recognition of the TACTAAC box during mRNA splicing in yeast involves base-pairing to the U2-like snRNA. Cell 49: 229–239.
-
(1987)
Cell
, vol.49
, pp. 229-239
-
-
Parker, R.1
Siliciano, P.2
Guthrie, C.3
-
24
-
-
0343851620
-
ATP can be dispensable for prespliceosome formation in yeast
-
Perriman R, Ares M Jr. 2000. ATP can be dispensable for prespliceosome formation in yeast. Genes Dev 14: 97–107.
-
(2000)
Genes Dev
, vol.14
, pp. 97-107
-
-
Perriman, R.1
Ares, M.2
-
25
-
-
34147174235
-
Rearrangement of competing U2 RNA helices within the spliceosome promotes multiple steps in splicing
-
Perriman R, Ares M Jr. 2007. Rearrangement of competing U2 RNA helices within the spliceosome promotes multiple steps in splicing. Genes Dev 21: 821–834.
-
(2007)
Genes Dev
, vol.21
, pp. 821-834
-
-
Perriman, R.1
Ares, M.2
-
26
-
-
77951956596
-
Invariant U2 snRNA nucleotides form a stem loop to recognize the intron early in splicing
-
Perriman R, Ares M Jr. 2010. Invariant U2 snRNA nucleotides form a stem loop to recognize the intron early in splicing. Mol Cell 38: 416–427.
-
(2010)
Mol Cell
, vol.38
, pp. 416-427
-
-
Perriman, R.1
Ares, M.2
-
27
-
-
0345564842
-
ATP requirement for Prp5p function is determined by Cus2p and the structure of U2 small nuclear RNA
-
Perriman R, Barta I, Voeltz GK, Abelson J, Ares M Jr. 2003. ATP requirement for Prp5p function is determined by Cus2p and the structure of U2 small nuclear RNA. Proc Natl Acad Sci 100: 13857–13862.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 13857-13862
-
-
Perriman, R.1
Barta, I.2
Voeltz, G.K.3
Abelson, J.4
Ares, M.5
-
28
-
-
2342522014
-
Suppression of multiple substrate mutations by spliceosomal prp8 alleles suggests functional correlations with ribosomal ambiguity mutants
-
Query CC, Konarska MM. 2004. Suppression of multiple substrate mutations by spliceosomal prp8 alleles suggests functional correlations with ribosomal ambiguity mutants. Mol Cell 14: 343–353.
-
(2004)
Mol Cell
, vol.14
, pp. 343-353
-
-
Query, C.C.1
Konarska, M.M.2
-
29
-
-
0027428138
-
Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA
-
Ruby SW, Chang T-H, Abelson J. 1993. Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA. Genes Dev 7: 1909–1925.
-
(1993)
Genes Dev
, vol.7
, pp. 1909-1925
-
-
Ruby, S.W.1
Chang, T.-H.2
Abelson, J.3
-
30
-
-
0027065506
-
A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis
-
Schwer B, Guthrie C. 1992. A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis. EMBO J 11: 5033–5040.
-
(1992)
EMBO J
, vol.11
, pp. 5033-5040
-
-
Schwer, B.1
Guthrie, C.2
-
31
-
-
84863022278
-
A U1–U2 snRNP interaction network during intron definition
-
Shao W, Kim H-S, Cao Y, Xu Y-Z, Query CC. 2012. A U1–U2 snRNP interaction network during intron definition. Mol Cell Biol 32: 470–478.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 470-478
-
-
Shao, W.1
Kim, H.-S.2
Cao, Y.3
Xu, Y.-Z.4
Query, C.C.5
-
32
-
-
65549090941
-
Insights into branch nucleophile positioning and activation from an orthogonal pre-mRNA splicing system in yeast
-
Smith DJ, Konarska MM, Query CC. 2009. Insights into branch nucleophile positioning and activation from an orthogonal pre-mRNA splicing system in yeast. Mol Cell 34: 333–343.
-
(2009)
Mol Cell
, vol.34
, pp. 333-343
-
-
Smith, D.J.1
Konarska, M.M.2
Query, C.C.3
-
33
-
-
0032489021
-
Mechanical devices of the spliceosome: Motors, clocks, springs, and things
-
Staley JP, Guthrie C. 1998. Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell 92: 315–326.
-
(1998)
Cell
, vol.92
, pp. 315-326
-
-
Staley, J.P.1
Guthrie, C.2
-
34
-
-
34548842257
-
Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosome
-
Tanaka N, Aronova A, Schwer B. 2007. Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosome. Genes Dev 21: 2312–2325.
-
(2007)
Genes Dev
, vol.21
, pp. 2312-2325
-
-
Tanaka, N.1
Aronova, A.2
Schwer, B.3
-
35
-
-
0027534562
-
The yeast PRP19 protein is not tightly associated with small nuclear RNAs, but appears to associate with the spliceosome after binding of U2 to the pre-mRNA and prior to formation of the functional spliceosome
-
Tarn W-Y, Lee K-R, Cheng S-C. 1993. The yeast PRP19 protein is not tightly associated with small nuclear RNAs, but appears to associate with the spliceosome after binding of U2 to the pre-mRNA and prior to formation of the functional spliceosome. Mol Cell Biol 13: 1883–1891.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 1883-1891
-
-
Tarn, W.-Y.1
Lee, K.-R.2
Cheng, S.-C.3
-
36
-
-
0028365538
-
Functional association of essential splicing factor(S) with PRP19 in a protein complex
-
Tarn W-Y, Hsu C-H, Huang K-T, Chen H-R, Kao H-Y, Lee K-R, Cheng S-C. 1994. Functional association of essential splicing factor(s) with PRP19 in a protein complex. EMBO J 13: 2421–2431.
-
(1994)
EMBO J
, vol.13
, pp. 2421-2431
-
-
Tarn, W.-Y.1
Hsu, C.-H.2
Huang, K.-T.3
Chen, H.-R.4
Kao, H.-Y.5
Lee, K.-R.6
Cheng, S.-C.7
-
37
-
-
78650446117
-
DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps
-
Tseng C-K, Liu H-L, Cheng S-C. 2011. DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps. RNA 17: 145–154.
-
(2011)
RNA
, vol.17
, pp. 145-154
-
-
Tseng, C.-K.1
Liu, H.-L.2
Cheng, S.-C.3
-
38
-
-
60349104299
-
The spliceosome: Design principles of a dynamic RNP machine
-
Wahl MC, Will CL, Lü hrmann RL. 2009. The spliceosome: design principles of a dynamic RNP machine. Cell 136: 701–718.
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Lü Hrmann, R.L.3
-
39
-
-
43349094305
-
A BBP-Mud2p heterodimer mediates branchpoint recognition and influences splicing substrate abundance in budding yeast
-
Wang Q, Zhang L, Lynn B, Rymond BC. 2008. A BBP-Mud2p heterodimer mediates branchpoint recognition and influences splicing substrate abundance in budding yeast. Nucleic Acids Res 36: 2787–2798.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 2787-2798
-
-
Wang, Q.1
Zhang, L.2
Lynn, B.3
Rymond, B.C.4
-
40
-
-
71449119694
-
Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components
-
Warkocki Z, Odenwälder P, Schmitzová J, Platzmann F, Stark H, Urlaub H, Ficner R, Fabrizio P, Lü hrmann R. 2009. Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components. Nat Struct Mol Biol 16: 1237–1243.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 1237-1243
-
-
Warkocki, Z.1
Odenwälder, P.2
Schmitzová, J.3
Platzmann, F.4
Stark, H.5
Urlaub, H.6
Ficner, R.7
Fabrizio, P.8
Lü Hrmann, R.9
-
41
-
-
0027981641
-
Interactions between highly conserved U2 small nuclear RNA structures and Prp5p, Prp9p, Prp11p, and Prp21p proteins are required to ensure integrity of the U2 small nuclear ribonucleoprotein in Saccharomyces cerevisiae
-
Wells SE, Ares M Jr. 1994. Interactions between highly conserved U2 small nuclear RNA structures and Prp5p, Prp9p, Prp11p, and Prp21p proteins are required to ensure integrity of the U2 small nuclear ribonucleoprotein in Saccharomyces cerevisiae. Mol Cell Biol 14: 6337–6349.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6337-6349
-
-
Wells, S.E.1
Ares, M.2
-
43
-
-
0037119975
-
Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein
-
Will CL, Urlauh H, Achsel T, Gentzel M, Wilm M, Lü hrmann R. 2002. Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. EMBO J 21: 4978–4988.
-
(2002)
EMBO J
, vol.21
, pp. 4978-4988
-
-
Will, C.L.1
Urlauh, H.2
Achsel, T.3
Gentzel, M.4
Wilm, M.5
Lü Hrmann, R.6
-
44
-
-
36749080450
-
Competition between the ATPase Prp5 and branch region-U2 snRNA pairing modulates the fidelity of spliceosome assembly
-
Xu Y-Z, Query CC. 2007. Competition between the ATPase Prp5 and branch region-U2 snRNA pairing modulates the fidelity of spliceosome assembly. Mol Cell 28: 838–849.
-
(2007)
Mol Cell
, vol.28
, pp. 838-849
-
-
Xu, Y.-Z.1
Query, C.C.2
-
45
-
-
1542380571
-
Prp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA
-
Xu Y-Z, Newnham CM, Kameoka S, Huang T, Konarska MM, Query CC. 2004. Prp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA. EMBO J 23: 376–385.
-
(2004)
EMBO J
, vol.23
, pp. 376-385
-
-
Xu, Y.-Z.1
Newnham, C.M.2
Kameoka, S.3
Huang, T.4
Konarska, M.M.5
Query, C.C.6
-
46
-
-
0031865048
-
CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif
-
Yan D, Perriman R, Igel H, Howe KJ, Neville M, AresMJr. 1998. CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif. Mol Cell Biol 18: 5000–5009.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5000-5009
-
-
Yan, D.1
Perriman, R.2
Igel, H.3
Howe, K.J.4
Neville, M.5
-
47
-
-
84877265326
-
Splicing proofreading at 59 splice sites by ATPase Prp28p
-
Yang F, Wang X-Y, Zhang Z-M, Pu J, Fan Y-J, Zhou J, Query CC, Xu Y-Z. 2013. Splicing proofreading at 59 splice sites by ATPase Prp28p. Nucleic Acids Res 41: 4660–4670.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 4660-4670
-
-
Yang, F.1
Wang, X.-Y.2
Zhang, Z.-M.3
Pu, J.4
Fan, Y.-J.5
Zhou, J.6
Query, C.C.7
Xu, Y.-Z.8
-
48
-
-
84890154131
-
Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly
-
Zhang ZM, Yang F, Zhang J, Tang Q, Li J, Gu J, Zhou J, Xu YZ. 2013. Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly. Cell Rep 5: 1269–1278.
-
(2013)
Cell Rep
, vol.5
, pp. 1269-1278
-
-
Zhang, Z.M.1
Yang, F.2
Zhang, J.3
Tang, Q.4
Li, J.5
Gu, J.6
Zhou, J.7
Xu, Y.Z.8
|