Combined NADPH oxidase 1 and interleukin 10 deficiency induces chronic endoplasmic reticulum stress and causes ulcerative colitis-like disease in mice

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Tréton, Xavier ^a,b,c,d   Pedruzzi, Eric ^a,b,d   Guichard, Cécile ^b,e   Ladeiro, Yannick ^a,b,d   Sedghi, Shirin ^a,b,d   Vallée, Mélissa ^a,b,d   Fernandez, Neike ^a,b,d   Bruyère, Emilie ^f   Woerther, Paul Louis ^g   Ducroc, Robert ^a,b,d   Montcuquet, Nicolas ^b,e   Freund, Jean Noel ^e   Van Seuningen, Isabelle ^f   Barreau, Frédérick ^b,d,e   Marah, Assiya ^a,b,c,d   Hugot, Jean Pierre ^b,d,e   Cazals Hatem, Dominique ^a,b,c,d   Bouhnik, Yoram ^a,b,c,d   Daniel, Fanny ^a,b,d   Ogier Denis, Eric ^a,b,d  

^a CENTRE DE RECHERCHE SUR L INFLAMMATION   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c BEAUJON HOSPITAL   (France)

^d Laboratory of Excellence Labex INFLAMEX   (France)

^e INSERM   (France)

^f JEAN PIERRE AUBERT RESEARCH CENTER   (France)

^g BICHAT HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; INITIATION FACTOR 2ALPHA; INTERLEUKIN 10; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN PP1R15A; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; MESSENGER RNA; OXIDOREDUCTASE; PPP1R15A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME DEFICIENCY; GOBLET CELL; HUMAN; HUMAN TISSUE; IMMUNOPATHOLOGY; INFLAMMATION; MOUSE; MOUSE MODEL; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PROTEIN DEFICIENCY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REMISSION; SIGNAL TRANSDUCTION; ULCERATIVE COLITIS; ANIMAL; C57BL MOUSE; CASE CONTROL STUDY; CELL CULTURE; CELL PROLIFERATION; COLITIS, ULCERATIVE; COLON; COMPARATIVE STUDY; DISEASE MODEL; ENDOPLASMIC RETICULUM; ENZYME IMMUNOASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; KNOCKOUT MOUSE; MALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CELL PROLIFERATION; CELLS, CULTURED; COLITIS, ULCERATIVE; COLON; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; INFLAMMATION; INTERLEUKIN-10; INTESTINAL MUCOSA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NADH, NADPH OXIDOREDUCTASES; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UNFOLDED PROTEIN RESPONSE;

EID: 84920484402     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0101669     Document Type: Article

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