Curcumin promotes apoptosis by activating the p53-miR-192-5p/215-XIAP pathway in non-small cell lung cancer

Cancer Letters

Volumn 357, Issue 1, 2015, Pages 196-205

  Ye, Mingxiang ^a,b   Zhang, Jin ^c   Zhang, Jiän ^b   Miao, Qing ^b,c   Yao, Libo ^b   Zhang, Jian ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c 401 Hospital of PLA   (China)

Author keywords

Curcumin; MiRNA; Non small cell lung cancer; P53; Tet on system; XIAP

Indexed keywords

ARGININE; CURCUMIN; HISTIDINE; MICRORNA; MICRORNA 192 5P; MICRORNA 215; MUTANT PROTEIN; PROTEIN P53; TETRACYCLINE; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; MIRN192 MICRORNA, HUMAN; MIRN212 MICRORNA, HUMAN; TP53 PROTEIN, HUMAN; XIAP PROTEIN, HUMAN;

A427 CELL LINE; A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FUNCTIONAL ASSESSMENT; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION SYSTEM; GENE INDUCTION; H460 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROARRAY ANALYSIS; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN RNA BINDING; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; RNA ANALYSIS; TREATMENT RESPONSE; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CARCINOMA, NON-SMALL-CELL LUNG; DRUG EFFECTS; GENETICS; LUNG NEOPLASMS; METABOLISM; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CURCUMIN; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84920478874     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.11.028     Document Type: Article

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