Hyperhomocysteinemia and thrombotic vascular disease;Hyperhomozysteinamie: Risikofaktor fur arterielle und venose thrombotische erkrankungen

Vasa - Journal of Vascular Diseases

Volumn 28, Issue 3, 1999, Pages 151-155

  Wuillemin, W A ^a   Solenthaler, M ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Arterial thrombosis; Homocysteine metabolism; Hyperhomocysteinemia; Venous thrombosis

Indexed keywords

COBALAMIN; CYSTEINE; FOLIC ACID; HOMOCYSTEINE; METHIONINE; PYRIDOXINE; CYANOCOBALAMIN;

AMINO ACID METABOLISM; ATHEROGENESIS; ATHEROSCLEROSIS; CEREBROVASCULAR DISEASE; CORONARY ARTERY DISEASE; DEEP VEIN THROMBOSIS; HOMOCYSTINURIA; HUMAN; HYPERHOMOCYSTEINEMIA; LUNG EMBOLISM; PATHOGENESIS; PERIPHERAL OCCLUSIVE ARTERY DISEASE; REVIEW; RISK FACTOR; THROMBOEMBOLISM; THROMBOGENESIS; VASCULAR DISEASE; ARTERIOSCLEROSIS; BLOOD;

ARTERIOSCLEROSIS; FOLIC ACID; HOMOCYSTEINE; HUMANS; HYPERHOMOCYSTEINEMIA; PYRIDOXINE; RISK FACTORS; THROMBOEMBOLISM; VITAMIN B 12;

EID: 84920326391     PISSN: 03011526     EISSN: None     Source Type: Journal    
DOI: 10.1024/0301-1526.28.3.151     Document Type: Review

References (24)

1. Amundsen T, Ueland PM, Waage A. Plasma homocysteine levels in patients with deep venous thrombosis. Arterioscler Thromb Vasc Biol 1995; 15: 1321-3.
2. Andersson A, Isaksson A, Hultberg B. Homocysteine export from erythrocytes and its implication for plasma sampling. Clin Chem 1992; 38: 1311-5.
3. Bienvenu T, Ankri A, Chadefaux B, Montalescot G, Kamoun P. Elevated total plasma homocysteine a risk factor for thrombosis: relation to coagulation and fibrinolytic parameters. Thromb Res 1993; 70: 123-9.
4. Bostom AG, Jacques PF, Nadeau MR, Williams RR, Ellison RC, Selhub J. Post-methionine load hyperhomocysteinemia in persons with normal fasting total plasma homocysteine - initial results from the NHLBI family heart study. Atherosclerosis 1995; 116: 147-53.
5. Boushey CJ, Beresford SAA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. JAMA 1995; 274: 1049-57.
6. Brattström L, Tengborn L, Lagerstedt C, Israelsson B, Hultberg B. Plasma Homocysteine in venous thromboembolism. Haemostasis 1991; 21: 51-7.
7. D Angelo A, Selhub J. Homocysteine and thromboticdisease. Blood 1997; 90: 1-11.
8. den Heijer M, Blom HJ, Gerrits WBJ, Rosendaal FR, Haak HL, Wijermans PW, Bos GMJ. Is hyperhomocysteinaemia a risk factor for recurrent venous thrombosis? Lancet 1995; 345: 882-5.
9. den Heijer M, Brouwer IA, Bos GMJ, Blom HJ, van der Put NMJ, Spaans AP Rosendaal FR, Thomas CMG, Haak HL, Wijermans PW, Gerrits WBJ. Vitamin supplementation reduces blood homocysteine levels. A controlled trial in patients with venous thrombosis and healthy volunteers. Arterioscler Thromb Vasc Biol 1998; 18: 356-61.
10. den Heijer M, Koster T, Blom HJ, Bos GMJ, Briet E, Reitsma PH, Vandenbroucke JP, Rosendaal FR. Hyperhomocysteinemia as a risk factor for deep-vein thrombosis. N Engl J Med 1996; 334: 759-62.
11. Falcon CR, Cattaneo M, Panzeri D, Martinelli I, Mannucci PM. High prevalence of hyperhomocyst(e)inemia in patients with juvenile venous thrombosis. Arterioscler Thromb 1994; 14: 1080-3.
12. Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJH, den Heijer M, Kluijtmans LAJ, van den Heuvel LP, Rozen R. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nature Gen 1995; 10: 111-3.
13. Graham IM. for the European concerted Action Project. Plasma homocysteine as a risk factor for vascular disease. JAMA 1997; 277: 1775-81.
14. Kang S-S, Zhou J, Wong PWK, Kowalisyn J, Strokosch G. Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet 1988; 43: 414-21.
15. Malinow MR. Plasma homocyst(e)ine: a risk factor for arterial occlusive diseases. J Nutr 1996; 126: 1238S-43S.
16. Perry IJ, Refsum H, Morris RW, Ebrahim SB, Ueland PM, Shaper AG. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet 1995; 346: 1395-8.
17. 6 from diet and supplements in relation to risk of coronary heart disease among women. JAMA 1998; 279: 359-64.
18. Selhub J, Jacques PF, Bostom AG, DAgostino RB, Wilson PWF, Belanger AJ, O'Leary DH, Wolf PA, Schaefer EJ, Rosenberg IH. Association between plasma homocysteine concentration and extracranial carotid-artery stenosis. N Engl J Med 1995; 332: 286-91.
19. Selhub J, Jaques PF, Wilson PWF, Rush D, Rosenberg JH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993; 270: 2693-8.
20. Simioni P, Prandoni P, Burlina A, Tormene D, Sardella C, Ferrari V, Benedetti L, Girolami A. Hyperhomocysteinemia and deep-vein thrombosis. A case-control study. Thromb Haemost 1996; 76: 883-6.
21. Stein JH, McBride PE. Hyperhomocysteinemia and atherosclerotic vascular disease. Arch Intern Med 1998; 158: 1301-6.
22. Trialist'Collaboration HL. Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials. BMJ 1998; 316: 894-8.
23. Welch GN, Loscalzo J. Homocysteine and atherothrombosis. N Engl J Med 1998; 338: 1042-50.
24. Wilcken DE, Wilcken B. The pathogenesis of coronary artery disease. A possible role for methionine metabolism. J Clin Invest 1976; 57: 1079-82.