Impact of admission glucose and diabetes on recanalization and outcome after intra-arterial thrombolysis for ischaemic stroke

International Journal of Stroke

Volumn 9, Issue 8, 2014, Pages 985-991

  Arnold, Marcel ^a   Mattle, Selina ^a   Galimanis, Aekaterini ^a   Kappeler, Liliane ^a   Fischer, Urs ^a   Jung, Simon ^a   De Marchis, Gian Marco ^a   Gralla, Jan ^b   Mono, Marie Luise ^a   Brekenfeld, Caspar ^b   Meier, Niklaus ^a   Nedeltchev, Krassen ^a   Schroth, Gerhard ^b   Mattle, Heinrich P ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Acute stroke therapy; Diabetes; Glucose; Intra arterial thrombolysis; Outcome; Recanalization

Indexed keywords

GLUCOSE;

AGED; BRAIN ISCHEMIA; COMPLICATION; DIABETES MELLITUS; FEMALE; FIBRINOLYTIC THERAPY; HUMAN; INTRAARTERIAL DRUG ADMINISTRATION; INTRACRANIAL HEMORRHAGES; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE AGED; MORTALITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PROCEDURES; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; STROKE; TREATMENT OUTCOME;

AGED; BRAIN ISCHEMIA; DIABETES MELLITUS; FEMALE; GLUCOSE; HUMANS; INJECTIONS, INTRA-ARTERIAL; INTRACRANIAL HEMORRHAGES; MAGNETIC RESONANCE ANGIOGRAPHY; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; STROKE; THROMBOLYTIC THERAPY; TREATMENT OUTCOME;

EID: 84920269415     PISSN: 17474930     EISSN: 17474949     Source Type: Journal    
DOI: 10.1111/j.1747-4949.2012.00879.x     Document Type: Article

References (39)

1. Bruno A, Biller J, Adams HP Jr etal. Acute blood glucose level and outcome from ischemic stroke. Neurology 1999; 52:280-284.
2. Gisselsson L, Smith ML, Siesjö BK. Hyperglycemia and focal brain ischemia. J Cereb Blood Flow Metab 1999; 19:288-297.
3. Mayer RE, Yamaguchi S. Nervous system effects of cardiac arrest in monkeys. Arch Neurol 1977; 34:65-74.
4. Kagansky N, Levy S, Knobler H. The role of hyperglycemia in acute stroke. Arch Neurol 2001; 58:1209-1212.
5. Kruyt ND, Biessels GJ, DeVries JH, Roos YB. Hyperglycemia in acute ischemic stroke: pathophysiology and clinical management. Nat Rev Neurol 2010; 6:145-155.
6. Ribo M, Molina C, Montaner J etal. Acute hyperglycemia state is associated with lower tPA-induced recanalization rates in stroke patients. Stroke 2005; 36:1705-1709.
7. Bruno A, Levine SR, Frankel MR etal.; NINDS rt-PA Stroke Study Group. Admission glucose levels and clinical outcomes in the NINDS rt-PA Stroke Trial. Neurology 2002; 59:669-674.
8. Ahmed N, Dávalos A, Eriksson N etal.; for the SITS Investigators. Association of admission blood glucose and outcome in patients treated with intravenous thrombolysis. Arch Neurol 2010; 67:1123-1130.
9. Oppenheimer SM, Hoffbrand BI, Oswald GA, Yudkin JS. Diabetes mellitus and early mortality from stroke. BMJ 1985; 291:1014-1015.
10. Kiers L, Davis SM, Larkins R etal. Stroke topography and outcome in relation to hyperglycemia and diabetes. J Neurol Neurosurg Psychiatry 1992; 55:263-270.
11. Zangerle A, Kiechl S, Spiegel M etal. Recanalisation after thrombolysis in stroke patients. Neurology 2007; 68:39-44.
12. De Silva DA, Ebinger M, Christensen S etal.; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators. Baseline diabetic status and admission blood glucose were poor prognostic factors in the EPITHET Trial. Cerebrovasc Dis 2010; 29:14-21.
13. Demchuk AM, Morgenstern LB, Krieger DW etal. Serum glucose level and diabetes predict tissue plasminogen activator-related intracerebral hemorrhage in acute ischemic stroke. Stroke 1999; 30:34-39.
14. Kase CS, Furlan AJ, Wechsler LR etal. Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke: the PROACT II trial. Neurology 2001; 57:1603-1610.
15. Arnold M, Schroth G, Nedeltchev K etal. Intra-arterial thrombolysis in 100 patients with acute stroke due to middle cerebral artery occlusion. Stroke 2002; 33:1828-1833.
16. Arnold M, Nedeltchev K, Schroth G etal. Clinical and radiological predictors of recanalization and outcome of 40 patients with acute basilar artery occlusion treated with intra-arterial thrombolysis. J Neurol Neurosurg Psychiatry 2004; 75:857-862.
17. Nedeltchev K, Fischer U, Arnold M etal. Long-term effect of intra-arterial thrombolysis in stroke. Stroke 2006; 37:3002-3007.
18. Brekenfeld C, Remonda L, Nedeltchev K etal. Symptomatic intracranial haemorrhage after intra-arterial thrombolysis in acute ischaemic stroke: assessment of 294 patients treated with urokinase. J Neurol Neurosurg Psychiatry 2007; 78:280-285.
19. Arnold M, Halpern M, Meier N etal. Age-dependent differences in demographics, risk factors, co-morbidity, etiology, management, and clinical outcome of acute ischemic stroke. J Neurol 2008; 255:1503-1507.
20. TIMI Study Group. The Thrombolysis in Myocardial Infarction (TIMI) trial. Phase I findings. N Engl J Med 1985; 312:932-936.
21. Adams HP Jr, Bendixen BH, Kappelle LJ etal. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993; 24:35-41.
22. van Swieten JC, Koudstaal PJ, Visser MC, Schouten HJ, van Gijn J. Interobserver agreement for the assessment of handicap in stroke patients. Stroke 1988; 19:604-607.
23. Davis SM, Donnan GA. Basilar artery thrombosis: recanalization is the key. Stroke 2006; 37:2440.
24. Tomsick T, Broderick J, Carrozella J etal. Revascularization results in the Interventional Management of Stroke II trial. AJNR Am J Neuroradiol 2008; 29:582-587.
25. Pandolfi A, Giaccari A, Cilli C etal. Acute hyperglycemia and acute hyperinsulinemia decrease plasma fibrinolytic activity and increase plasminogen activator inhibitor type 1 in the rat. Acta Diabetol 2001; 38:71-76.
26. Vague P, Juhan-Vague I, Aillaud MF etal. Correlation between blood fibrinolytic activity, plasminogen activator inhibitor level, plasma insulin level, and relative body weight in normal and obese subjects. Metabolism 1986; 35:250-253.
27. Wechsler LR, Roberts R, Furlan AJ etal. Factors influencing outcome and treatment effect in PROACT II. Stroke 2003; 34:1224-1229.
28. Hallevi H, Barreto AD, Liebeskind DS etal. Identifying patients at high risk for poor outcome after intra-arterial therapy for acute ischemic stroke. Stroke 2009; 40:1780-1785.
29. Zairis MN, Lyras AG, Makrygiannis SS etal. Type 2 diabetes and intravenous thrombolysis outcome in the setting of ST elevation myocardial infarction. Diabetes Care 2004; 27:967-971.
30. Madsen MM, Busk M, Søndergaard HM etal.; DANAMI-2 Investigators. Does diabetes mellitus abolish the beneficial effect of primary coronary angioplasty on long-term risk of reinfarction after acute ST-segment elevation myocardial infarction compared with fibrinolysis? (A DANAMI-2 substudy). Am J Cardiol 2005; 96:1469-1475.
31. The NINDS t-PA Stroke Study Group. Generalized efficacy of t-PA for acute stroke. Subgroup analysis of the NINDS t-PA Stroke Trial. Stroke 1997; 28:2119-2125.
32. Parsons MW, Barber PA, Desmond PM etal. Acute hyperglycemia adversely affects stroke outcome: a magnetic resonance imaging and spectroscopy study. Ann Neurol 2002; 52:20-24.
33. Li PA, Shuaib A, Miyashita H, He QP, Siesjö BK, Warner DS. Hyperglycemia enhances extracellular glutamate accumulation in rats subjected to forebrain ischemia. Stroke 2000; 31:183-192.
34. Dietrich WD, Alonso O, Busto R. Moderate hyperglycemia worsens acute blood-brain barrier injury after forebrain ischemia in rats. Stroke 1993; 24:111-116.
35. Pulsinelli WA, Waldman S, Rawlinson D, Plum F. Moderate hyperglycemia augments ischemic brain damage: a neuropathologic study in the rat. Neurology 1982; 32:1239-1246.
36. Gray CS, Hildreth AJ, Sandercock PA, O'Connell JE, Johnston DE, Cartlidge NE, GIST Trialists Collaboration. Glucose-potassium-insulin infusions in the management of post-stroke hyperglycaemia: the UK Glucose Insulin in Stroke Trial (GIST-UK). Lancet Neurol 2007; 6:397-406.
37. Katzan IL, Furlan AJ, Lloyd LE etal. Use of tissue-type plasminogen activator for acute ischemic stroke: the Cleveland area experience. JAMA 2000; 283:1151-1158.
38. De Courten-Myers GM, Kleinholz M, Holm P etal. Hemorrhagic infarct conversion in experimental stroke. Ann Emerg Med 1992; 21:120-126.
39. Fuentes B, Ortega-Casarrubios MA, Sanjosé B etal. Persistent hyperglycemia >155mg/dl in acute ischemic stroke patients: how well are we correcting it? Implications for outcome. Stroke 2010; 41:2362-2365.