-
1
-
-
33745919520
-
Epidemiology of Parkinson's disease
-
de Lau, L. M.; Breteler, M. M. Epidemiology of Parkinson's disease Lancet Neurol. 2006, 5 (6) 525-535
-
(2006)
Lancet Neurol.
, vol.5
, Issue.6
, pp. 525-535
-
-
De Lau, L.M.1
Breteler, M.M.2
-
2
-
-
19344378419
-
Prevalence of Parkinson's disease in China
-
Rocca, W. A. Prevalence of Parkinson's disease in China Lancet Neurol. 2005, 4 (6) 328-329
-
(2005)
Lancet Neurol.
, vol.4
, Issue.6
, pp. 328-329
-
-
Rocca, W.A.1
-
3
-
-
33846572874
-
Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030
-
Dorsey, E.; Constantinescu, R.; Thompson, J.; Biglan, K.; Holloway, R.; Kieburtz, K.; Marshall, F.; Ravina, B.; Schifitto, G.; Siderowf, A. Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030 Neurology 2007, 68 (5) 384-386
-
(2007)
Neurology
, vol.68
, Issue.5
, pp. 384-386
-
-
Dorsey, E.1
Constantinescu, R.2
Thompson, J.3
Biglan, K.4
Holloway, R.5
Kieburtz, K.6
Marshall, F.7
Ravina, B.8
Schifitto, G.9
Siderowf, A.10
-
4
-
-
84880229894
-
Parkinson's disease - The debate on the clinical phenomenology, aetiology, pathology and pathogenesis
-
Jenner, P.; Morris, H. R.; Robbins, T. W.; Goedert, M.; Hardy, J.; Ben-Shlomo, Y.; Bolam, P.; Burn, D.; Hindle, J. V.; Brooks, D. Parkinson's disease - the debate on the clinical phenomenology, aetiology, pathology and pathogenesis J. Parkinson's Dis. 2013, 3 (1) 1-11
-
(2013)
J. Parkinson's Dis.
, vol.3
, Issue.1
, pp. 1-11
-
-
Jenner, P.1
Morris, H.R.2
Robbins, T.W.3
Goedert, M.4
Hardy, J.5
Ben-Shlomo, Y.6
Bolam, P.7
Burn, D.8
Hindle, J.V.9
Brooks, D.10
-
5
-
-
84878253190
-
Management of motor and non-motor symptoms in Parkinson's disease
-
Sprenger, F.; Poewe, W. Management of motor and non-motor symptoms in Parkinson's disease CNS Drugs 2013, 27 (4) 259-272
-
(2013)
CNS Drugs
, vol.27
, Issue.4
, pp. 259-272
-
-
Sprenger, F.1
Poewe, W.2
-
6
-
-
84863578451
-
Crosstalk between metabolic and neuropsychiatric disorders
-
Kaidanovich-Beilin, O.; Cha, D. S.; McIntyre, R. S. Crosstalk between metabolic and neuropsychiatric disorders F1000 Biol. Repl 2012, 4, 14
-
(2012)
F1000 Biol. Repl
, vol.4
, pp. 14
-
-
Kaidanovich-Beilin, O.1
Cha, D.S.2
McIntyre, R.S.3
-
7
-
-
55849122639
-
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
-
Henchcliffe, C.; Beal, M. F. Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis Nat. Clin. Pract. Neurol. 2008, 4 (11) 600-609
-
(2008)
Nat. Clin. Pract. Neurol.
, vol.4
, Issue.11
, pp. 600-609
-
-
Henchcliffe, C.1
Beal, M.F.2
-
8
-
-
67049134827
-
Metabolomics tools for identifying biomarkers for neuropsychiatric diseases
-
Quinones, M. P.; Kaddurah-Daouk, R. Metabolomics tools for identifying biomarkers for neuropsychiatric diseases Neurobiol. Dis. 2009, 35 (2) 165-176
-
(2009)
Neurobiol. Dis.
, vol.35
, Issue.2
, pp. 165-176
-
-
Quinones, M.P.1
Kaddurah-Daouk, R.2
-
9
-
-
84905027580
-
NMR Metabolomics Analysis of Parkinson's Disease
-
Lei, S.; Powers, R. NMR Metabolomics Analysis of Parkinson's Disease Curr. Metabolomics 2013, 1 (3) 191-209
-
(2013)
Curr. Metabolomics
, vol.1
, Issue.3
, pp. 191-209
-
-
Lei, S.1
Powers, R.2
-
11
-
-
84886413067
-
3-hydroxykynurenine and other Parkinson's disease biomarkers discovered by metabolomic analysis
-
Lewitt, P. A.; Li, J.; Lu, M.; Beach, T. G.; Adler, C. H.; Guo, L. 3-hydroxykynurenine and other Parkinson's disease biomarkers discovered by metabolomic analysis Mov. Disord. 2013, 28 (12) 1653-1660
-
(2013)
Mov. Disord.
, vol.28
, Issue.12
, pp. 1653-1660
-
-
Lewitt, P.A.1
Li, J.2
Lu, M.3
Beach, T.G.4
Adler, C.H.5
Guo, L.6
-
12
-
-
51649116593
-
Metabolomic analysis of urine and serum in Parkinson's disease
-
Michell, A. W.; Mosedale, D.; Grainger, D. J.; Barker, R. A. Metabolomic analysis of urine and serum in Parkinson's disease Metabolomics 2008, 4 (3) 191-201
-
(2008)
Metabolomics
, vol.4
, Issue.3
, pp. 191-201
-
-
Michell, A.W.1
Mosedale, D.2
Grainger, D.J.3
Barker, R.A.4
-
13
-
-
38849159145
-
Metabolomic profiling to develop blood biomarkers for Parkinson's disease
-
Bogdanov, M.; Matson, W. R.; Wang, L.; Matson, T.; Saunders-Pullman, R.; Bressman, S. S.; Flint Beal, M. Metabolomic profiling to develop blood biomarkers for Parkinson's disease Brain 2008, 131 (Pt 2) 389-396
-
(2008)
Brain
, vol.131
, pp. 389-396
-
-
Bogdanov, M.1
Matson, W.R.2
Wang, L.3
Matson, T.4
Saunders-Pullman, R.5
Bressman, S.S.6
Flint Beal, M.7
-
14
-
-
84880708061
-
Metabolomics and In-Silico Analysis Reveal Critical Energy Deregulations in Animal Models of Parkinson's Disease
-
Poliquin, P. O.; Chen, J.; Cloutier, M.; Trudeau, L.-é.; Jolicoeur, M. Metabolomics and In-Silico Analysis Reveal Critical Energy Deregulations in Animal Models of Parkinson's Disease PLoS One 2013, 8 (7) e69146
-
(2013)
PLoS One
, vol.8
, Issue.7
, pp. 69146
-
-
Poliquin, P.O.1
Chen, J.2
Cloutier, M.3
Jolicoeur, M.4
-
15
-
-
84892483066
-
The metabolomics of alpha-synuclein (SNCA) gene deletion and mutation in mouse brain
-
Musgrove, R.; Horne, J.; Wilson, R.; King, A.; Edwards, L.; Dickson, T. The metabolomics of alpha-synuclein (SNCA) gene deletion and mutation in mouse brain Metabolomics 2014, 10 (1) 114-122
-
(2014)
Metabolomics
, vol.10
, Issue.1
, pp. 114-122
-
-
Musgrove, R.1
Horne, J.2
Wilson, R.3
King, A.4
Edwards, L.5
Dickson, T.6
-
16
-
-
70449552850
-
Metabolomic profiling in LRRK2-related Parkinson's disease
-
Johansen, K. K.; Wang, L.; Aasly, J. O.; White, L. R.; Matson, W. R.; Henchcliffe, C.; Beal, M. F.; Bogdanov, M. Metabolomic profiling in LRRK2-related Parkinson's disease PLoS One 2009, 4 (10) e7551
-
(2009)
PLoS One
, vol.4
, Issue.10
, pp. 7551
-
-
Johansen, K.K.1
Wang, L.2
Aasly, J.O.3
White, L.R.4
Matson, W.R.5
Henchcliffe, C.6
Beal, M.F.7
Bogdanov, M.8
-
17
-
-
84886066926
-
Serum metabolomics of slow vs. Rapid motor progression Parkinson's disease: A pilot study
-
Roede, J. R.; Uppal, K.; Park, Y.; Lee, K.; Tran, V.; Walker, D.; Strobel, F. H.; Rhodes, S. L.; Ritz, B.; Jones, D. P. Serum metabolomics of slow vs. rapid motor progression Parkinson's disease: a pilot study PLoS One 2013, 8 (10) e77629
-
(2013)
PLoS One
, vol.8
, Issue.10
, pp. 77629
-
-
Roede, J.R.1
Uppal, K.2
Park, Y.3
Lee, K.4
Tran, V.5
Walker, D.6
Strobel, F.H.7
Rhodes, S.L.8
Ritz, B.9
Jones, D.P.10
-
18
-
-
34447633928
-
Evolution of cognitive dysfunction in an incident Parkinson's disease cohort
-
Williams-Gray, C. H.; Foltynie, T.; Brayne, C. E.; Robbins, T. W.; Barker, R. A. Evolution of cognitive dysfunction in an incident Parkinson's disease cohort Brain 2007, 130 (Pt 7) 1787-1798
-
(2007)
Brain
, vol.130
, pp. 1787-1798
-
-
Williams-Gray, C.H.1
Foltynie, T.2
Brayne, C.E.3
Robbins, T.W.4
Barker, R.A.5
-
19
-
-
84864828304
-
Urine Metabolomics Analysis for Biomarker Discovery and Detection of Jaundice Syndrome in Patients with Liver Disease
-
Wang, X. J.; Zhang, A. H.; Han, Y.; Wang, P.; Sun, H.; Song, G. C.; Dong, T. W.; Yuan, Y.; Yuan, X. X.; Zhang, M.; Xie, N.; Zhang, H.; Dong, H.; Dong, W. Urine Metabolomics Analysis for Biomarker Discovery and Detection of Jaundice Syndrome in Patients With Liver Disease Mol. Cell. Proteomics 2012, 11 (8) 370-380
-
(2012)
Mol. Cell. Proteomics
, vol.11
, Issue.8
, pp. 370-380
-
-
Wang, X.J.1
Zhang, A.H.2
Han, Y.3
Wang, P.4
Sun, H.5
Song, G.C.6
Dong, T.W.7
Yuan, Y.8
Yuan, X.X.9
Zhang, M.10
Xie, N.11
Zhang, H.12
Dong, H.13
Dong, W.14
-
20
-
-
84863024905
-
Distinct urinary metabolic profile of human colorectal cancer
-
Cheng, Y.; Xie, G.; Chen, T.; Qiu, Y.; Zou, X.; Zheng, M.; Tan, B.; Feng, B.; Dong, T.; He, P.; Zhao, L.; Zhao, A.; Xu, L. X.; Zhang, Y.; Jia, W. Distinct urinary metabolic profile of human colorectal cancer J. Proteome Res. 2012, 11 (2) 1354-1363
-
(2012)
J. Proteome Res.
, vol.11
, Issue.2
, pp. 1354-1363
-
-
Cheng, Y.1
Xie, G.2
Chen, T.3
Qiu, Y.4
Zou, X.5
Zheng, M.6
Tan, B.7
Feng, B.8
Dong, T.9
He, P.10
Zhao, L.11
Zhao, A.12
Xu, L.X.13
Zhang, Y.14
Jia, W.15
-
21
-
-
79959913950
-
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
-
Dunn, W. B.; Broadhurst, D.; Begley, P.; Zelena, E.; Francis-McIntyre, S.; Anderson, N.; Brown, M.; Knowles, J. D.; Halsall, A.; Haselden, J. N.; Nicholls, A. W.; Wilson, I. D.; Kell, D. B.; Goodacre, R. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry Nat. Protoc. 2011, 6 (7) 1060-1083
-
(2011)
Nat. Protoc.
, vol.6
, Issue.7
, pp. 1060-1083
-
-
Dunn, W.B.1
Broadhurst, D.2
Begley, P.3
Zelena, E.4
Francis-Mcintyre, S.5
Anderson, N.6
Brown, M.7
Knowles, J.D.8
Halsall, A.9
Haselden, J.N.10
Nicholls, A.W.11
Wilson, I.D.12
Kell, D.B.13
Goodacre, R.14
-
22
-
-
84878122042
-
Serum metabolomics reveals lipid metabolism variation between coronary artery disease and congestive heart failure: A pilot study
-
Luan, H.; Chen, X.; Zhong, S.; Yuan, X.; Meng, N.; Zhang, J.; Fu, J.; Xu, R.; Lee, C.; Song, S.; Jiang, H.; Xu, X. Serum metabolomics reveals lipid metabolism variation between coronary artery disease and congestive heart failure: a pilot study Biomarkers 2013, 18 (4) 314-321
-
(2013)
Biomarkers
, vol.18
, Issue.4
, pp. 314-321
-
-
Luan, H.1
Chen, X.2
Zhong, S.3
Yuan, X.4
Meng, N.5
Zhang, J.6
Fu, J.7
Xu, R.8
Lee, C.9
Song, S.10
Jiang, H.11
Xu, X.12
-
23
-
-
84896772976
-
Pregnancy-Induced Metabolic Phenotype Variations in Maternal Plasma
-
Luan, H.; Meng, N.; Liu, P.; Feng, Q.; Lin, S.; Fu, J.; Davidson, R.; Chen, X.; Rao, W.; Chen, F.; Jiang, H.; Xu, X.; Cai, Z.; Wang, J. Pregnancy-Induced Metabolic Phenotype Variations in Maternal Plasma J. Proteome Res. 2014, 13 (3) 1527-1536
-
(2014)
J. Proteome Res.
, vol.13
, Issue.3
, pp. 1527-1536
-
-
Luan, H.1
Meng, N.2
Liu, P.3
Feng, Q.4
Lin, S.5
Fu, J.6
Davidson, R.7
Chen, X.8
Rao, W.9
Chen, F.10
Jiang, H.11
Xu, X.12
Cai, Z.13
Wang, J.14
-
24
-
-
84855402302
-
CAMERA: An integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets
-
Kuhl, C.; Tautenhahn, R.; Bottcher, C.; Larson, T. R.; Neumann, S. CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets Anal. Chem. 2012, 84 (1) 283-289
-
(2012)
Anal. Chem.
, vol.84
, Issue.1
, pp. 283-289
-
-
Kuhl, C.1
Tautenhahn, R.2
Bottcher, C.3
Larson, T.R.4
Neumann, S.5
-
25
-
-
32444446805
-
XCMS: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification
-
Smith, C. A.; Want, E. J.; O'Maille, G.; Abagyan, R.; Siuzdak, G. XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification Anal. Chem. 2006, 78 (3) 779-787
-
(2006)
Anal. Chem.
, vol.78
, Issue.3
, pp. 779-787
-
-
Smith, C.A.1
Want, E.J.2
O'Maille, G.3
Abagyan, R.4
Siuzdak, G.5
-
26
-
-
77952205557
-
Global metabolic profiling procedures for urine using UPLC-MS
-
Want, E. J.; Wilson, I. D.; Gika, H.; Theodoridis, G.; Plumb, R. S.; Shockcor, J.; Holmes, E.; Nicholson, J. K. Global metabolic profiling procedures for urine using UPLC-MS Nat. Protoc. 2010, 5 (6) 1005-1018
-
(2010)
Nat. Protoc.
, vol.5
, Issue.6
, pp. 1005-1018
-
-
Want, E.J.1
Wilson, I.D.2
Gika, H.3
Theodoridis, G.4
Plumb, R.S.5
Shockcor, J.6
Holmes, E.7
Nicholson, J.K.8
-
27
-
-
84859568041
-
The metabolic footprint of aging in mice
-
Houtkooper, R. H.; Argmann, C.; Houten, S. M.; Canto, C.; Jeninga, E. H.; Andreux, P. A.; Thomas, C.; Doenlen, R.; Schoonjans, K.; Auwerx, J. The metabolic footprint of aging in mice Sci. Rep. 2011, 1
-
(2011)
Sci. Rep.
, pp. 1
-
-
Houtkooper, R.H.1
Argmann, C.2
Houten, S.M.3
Canto, C.4
Jeninga, E.H.5
Andreux, P.A.6
Thomas, C.7
Doenlen, R.8
Schoonjans, K.9
Auwerx, J.10
-
28
-
-
84884774681
-
Parkinson disease: New guidelines for diagnosis of Parkinson disease
-
Marti, M. J.; Tolosa, E. Parkinson disease: New guidelines for diagnosis of Parkinson disease Nat. Rev. Neurol. 2013, 9 (4) 190-191
-
(2013)
Nat. Rev. Neurol.
, vol.9
, Issue.4
, pp. 190-191
-
-
Marti, M.J.1
Tolosa, E.2
-
29
-
-
84864479791
-
MetaboAnalyst 2.0 - A comprehensive server for metabolomic data analysis
-
Web Server Issue
-
Xia, J.; Mandal, R.; Sinelnikov, I. V.; Broadhurst, D.; Wishart, D. S. MetaboAnalyst 2.0 - a comprehensive server for metabolomic data analysis Nucleic Acids Res. 2012, 40 (Web Server issue) W127-W133
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 127-W133
-
-
Xia, J.1
Mandal, R.2
Sinelnikov, I.V.3
Broadhurst, D.4
Wishart, D.S.5
-
30
-
-
79958044624
-
The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease
-
Campesan, S.; Green, E. W.; Breda, C.; Sathyasaikumar, K. V.; Muchowski, P. J.; Schwarcz, R.; Kyriacou, C. P.; Giorgini, F. The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease Curr. Biol. 2011, 21 (11) 961-966
-
(2011)
Curr. Biol.
, vol.21
, Issue.11
, pp. 961-966
-
-
Campesan, S.1
Green, E.W.2
Breda, C.3
Sathyasaikumar, K.V.4
Muchowski, P.J.5
Schwarcz, R.6
Kyriacou, C.P.7
Giorgini, F.8
-
31
-
-
79955749505
-
Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery
-
Pandey, U. B.; Nichols, C. D. Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery Pharmacol. Rev. 2011, 63 (2) 411-436
-
(2011)
Pharmacol. Rev.
, vol.63
, Issue.2
, pp. 411-436
-
-
Pandey, U.B.1
Nichols, C.D.2
-
32
-
-
70349731404
-
Biological fluid biomarkers in neurodegenerative parkinsonism
-
Eller, M.; Williams, D. R. Biological fluid biomarkers in neurodegenerative parkinsonism Nat. Rev. Neurol. 2009, 5 (10) 561-570
-
(2009)
Nat. Rev. Neurol.
, vol.5
, Issue.10
, pp. 561-570
-
-
Eller, M.1
Williams, D.R.2
-
33
-
-
83455217978
-
Plasma and urinary HPLC-ED determination of the ratio of 8-OHdG/2-dG in Parkinson's disease
-
Bolner, A.; Pilleri, M.; De Riva, V.; Nordera, G. P. Plasma and urinary HPLC-ED determination of the ratio of 8-OHdG/2-dG in Parkinson's disease Clin. Lab. 2011, 57 (11-12) 859-866
-
(2011)
Clin. Lab.
, vol.57
, Issue.1112
, pp. 859-866
-
-
Bolner, A.1
Pilleri, M.2
De Riva, V.3
Nordera, G.P.4
-
34
-
-
0031882472
-
Cortisol is higher in parkinsonism and associated with gait deficit
-
Charlett, A.; Dobbs, R. J.; Purkiss, A. G.; Wright, D. J.; Peterson, D. W.; Weller, C.; Dobbs, S. M. Cortisol is higher in parkinsonism and associated with gait deficit Acta Neurol. Scand. 1998, 97 (2) 77-85
-
(1998)
Acta Neurol. Scand.
, vol.97
, Issue.2
, pp. 77-85
-
-
Charlett, A.1
Dobbs, R.J.2
Purkiss, A.G.3
Wright, D.J.4
Peterson, D.W.5
Weller, C.6
Dobbs, S.M.7
-
35
-
-
80052620519
-
Salivary cortisol levels in Parkinson' disease and its correlation to risk behaviour
-
Djamshidian, A.; O'Sullivan, S. S.; Papadopoulos, A.; Bassett, P.; Shaw, K.; Averbeck, B. B.; Lees, A. Salivary cortisol levels in Parkinson' disease and its correlation to risk behaviour J. Neurol., Neurosurg. Psychiatry 2011, 82 (10) 1107-1111
-
(2011)
J. Neurol., Neurosurg. Psychiatry
, vol.82
, Issue.10
, pp. 1107-1111
-
-
Djamshidian, A.1
O'Sullivan, S.S.2
Papadopoulos, A.3
Bassett, P.4
Shaw, K.5
Averbeck, B.B.6
Lees, A.7
-
36
-
-
0030739052
-
Twenty-four hour cortisol release profiles in patients with Alzheimer's and Parkinson's disease compared to normal controls: Ultradian secretory pulsatility and diurnal variation
-
Hartmann, A.; Veldhuis, J. D.; Deuschle, M.; Standhardt, H.; Heuser, I. Twenty-four hour cortisol release profiles in patients with Alzheimer's and Parkinson's disease compared to normal controls: Ultradian secretory pulsatility and diurnal variation Neurobiol. Aging 1997, 18 (3) 285-289
-
(1997)
Neurobiol. Aging
, vol.18
, Issue.3
, pp. 285-289
-
-
Hartmann, A.1
Veldhuis, J.D.2
Deuschle, M.3
Standhardt, H.4
Heuser, I.5
-
37
-
-
79955599480
-
Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism
-
Ros-Bernal, F.; Hunot, S.; Herrero, M. T.; Parnadeau, S.; Corvol, J. C.; Lu, L. X.; Alvarez-Fischer, D.; Carrillo-de Sauvage, M. A.; Saurini, F.; Coussieu, C.; Kinugawa, K.; Prigent, A.; Hoglinger, G.; Hamon, M.; Tronche, F.; Hirsch, E. C.; Vyas, S. Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism Proc. Natl. Acad. Sci. U.S.A. 2011, 108 (16) 6632-6637
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, Issue.16
, pp. 6632-6637
-
-
Ros-Bernal, F.1
Hunot, S.2
Herrero, M.T.3
Parnadeau, S.4
Corvol, J.C.5
Lu, L.X.6
Alvarez-Fischer, D.7
Carrillo-De Sauvage, M.A.8
Saurini, F.9
Coussieu, C.10
Kinugawa, K.11
Prigent, A.12
Hoglinger, G.13
Hamon, M.14
Tronche, F.15
Hirsch, E.C.16
Vyas, S.17
-
38
-
-
42049088743
-
Stress accelerates neural degeneration and exaggerates motor symptoms in a rat model of Parkinson's disease
-
Smith, L. K.; Jadavji, N. M.; Colwell, K. L.; Perehudoff, S. K.; Metz, G. A. Stress accelerates neural degeneration and exaggerates motor symptoms in a rat model of Parkinson's disease Eur. J. Neurosci. 2008, 27 (8) 2133-2146
-
(2008)
Eur. J. Neurosci.
, vol.27
, Issue.8
, pp. 2133-2146
-
-
Smith, L.K.1
Jadavji, N.M.2
Colwell, K.L.3
Perehudoff, S.K.4
Metz, G.A.5
-
39
-
-
54049147675
-
Impact of glucocorticoids and chronic stress on progression of Parkinson's disease
-
Kibel, A.; Drenjancevic-Peric, I. Impact of glucocorticoids and chronic stress on progression of Parkinson's disease Med. Hypotheses 2008, 71 (6) 952-956
-
(2008)
Med. Hypotheses
, vol.71
, Issue.6
, pp. 952-956
-
-
Kibel, A.1
Drenjancevic-Peric, I.2
-
40
-
-
84920287413
-
Oxidative stress in the pathogenesis of Parkinson's disease
-
Bagieva, G. K.; Fedorova, T. N.; Stvolinsky, S. L.; Boldyrev, A. A.; Ivanova-Smolenskaya, I. A.; Illarioshkin, S. N. Oxidative stress in the pathogenesis of Parkinson's disease Mov. Disord. 2004, 19, S266-S266
-
(2004)
Mov. Disord.
, vol.19
, pp. 266-S266
-
-
Bagieva, G.K.1
Fedorova, T.N.2
Stvolinsky, S.L.3
Boldyrev, A.A.4
Ivanova-Smolenskaya, I.A.5
Illarioshkin, S.N.6
-
41
-
-
79958150863
-
Association between Urinary Excretion of Cortisol and Markers of Oxidatively Damaged DNA and RNA in Humans
-
Joergensen, A.; Broedbaek, K.; Weimann, A.; Semba, R. D.; Ferrucci, L.; Joergensen, M. B.; Poulsen, H. E., Association between Urinary Excretion of Cortisol and Markers of Oxidatively Damaged DNA and RNA in Humans. PLoS One 2011, 6, (6).
-
(2011)
PLoS One
, vol.6
, Issue.6
-
-
Joergensen, A.1
Broedbaek, K.2
Weimann, A.3
Semba, R.D.4
Ferrucci, L.5
Joergensen, M.B.6
Poulsen, H.E.7
-
42
-
-
33644543761
-
Expanding insights of mitochondrial dysfunction in Parkinson's disease
-
Abou-Sleiman, P. M.; Muqit, M. M. K.; Wood, N. W. Expanding insights of mitochondrial dysfunction in Parkinson's disease Nat. Rev. Neurosci. 2006, 7 (3) 207-219
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, Issue.3
, pp. 207-219
-
-
Abou-Sleiman, P.M.1
Muqit, M.M.K.2
Wood, N.W.3
-
43
-
-
0026584524
-
Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?
-
Beal, M. F. Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann. Neurol. 1992, 31 (2) 119-130
-
(1992)
Ann. Neurol.
, vol.31
, Issue.2
, pp. 119-130
-
-
Beal, M.F.1
-
44
-
-
84881532044
-
Reduction of Brain Mitochondrial beta-Oxidation Impairs Complex i and v in Chronic Alcohol Intake: The Underlying Mechanism for Neurodegeneration
-
Haorah, J.; Rump, T. J.; Xiong, H. G., Reduction of Brain Mitochondrial beta-Oxidation Impairs Complex I and V in Chronic Alcohol Intake: The Underlying Mechanism for Neurodegeneration. PLoS One 2013, 8, (8).
-
(2013)
PLoS One
, vol.8
, Issue.8
-
-
Haorah, J.1
Rump, T.J.2
Xiong, H.G.3
-
45
-
-
0034467745
-
Rapid diagnosis of organic acidemias and fatty-acid oxidation defects by quantitative electrospray tandem-MS acyl-carnitine analysis in plasma
-
Vreken, P.; van Lint, A. E.; Bootsma, A. H.; Overmars, H.; Wanders, R. J.; van Gennip, A. H. Rapid diagnosis of organic acidemias and fatty-acid oxidation defects by quantitative electrospray tandem-MS acyl-carnitine analysis in plasma Adv. Exp. Med. Biol. 1999, 466, 327-337
-
(1999)
Adv. Exp. Med. Biol.
, vol.466
, pp. 327-337
-
-
Vreken, P.1
Van Lint, A.E.2
Bootsma, A.H.3
Overmars, H.4
Wanders, R.J.5
Van Gennip, A.H.6
-
46
-
-
84864773894
-
Carnitine and Acylcarnitines Pharmacokinetic, Pharmacological and Clinical Aspects
-
Reuter, S. E.; Evans, A. M. Carnitine and Acylcarnitines Pharmacokinetic, Pharmacological and Clinical Aspects Clin. Pharmacokinet. 2012, 51 (9) 553-572
-
(2012)
Clin. Pharmacokinet.
, vol.51
, Issue.9
, pp. 553-572
-
-
Reuter, S.E.1
Evans, A.M.2
-
47
-
-
82355169156
-
Histamine pharmacology and new CNS drug targets
-
Tiligada, E.; Kyriakidis, K.; Chazot, P. L.; Passani, M. B. Histamine pharmacology and new CNS drug targets CNS Neurosci. Ther. 2011, 17 (6) 620-628
-
(2011)
CNS Neurosci. Ther.
, vol.17
, Issue.6
, pp. 620-628
-
-
Tiligada, E.1
Kyriakidis, K.2
Chazot, P.L.3
Passani, M.B.4
-
48
-
-
0025743723
-
Histamine metabolites and pros-methylimidazoleacetic acid in human cerebrospinal fluid
-
Prell, G. D.; Green, J. P. Histamine metabolites and pros-methylimidazoleacetic acid in human cerebrospinal fluid Agents Actions Suppl 1991, 33, 343-363
-
(1991)
Agents Actions Suppl
, vol.33
, pp. 343-363
-
-
Prell, G.D.1
Green, J.P.2
-
49
-
-
0036319037
-
Increased brain histamine levels in Parkinson's disease but not in multiple system atrophy
-
Rinne, J. O.; Anichtchik, O. V.; Eriksson, K. S.; Kaslin, J.; Tuomisto, L.; Kalimo, H.; Roytta, M.; Panula, P. Increased brain histamine levels in Parkinson's disease but not in multiple system atrophy J. Neurochem. 2002, 81 (5) 954-960
-
(2002)
J. Neurochem.
, vol.81
, Issue.5
, pp. 954-960
-
-
Rinne, J.O.1
Anichtchik, O.V.2
Eriksson, K.S.3
Kaslin, J.4
Tuomisto, L.5
Kalimo, H.6
Roytta, M.7
Panula, P.8
-
50
-
-
33751222269
-
Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor
-
Walterscheid, J. P.; Nghiem, D. X.; Kazimi, N.; Nutt, L. K.; McConkey, D. J.; Norval, M.; Ullrich, S. E. Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor Proc. Natl. Acad. Sci. U.S.A. 2006, 103 (46) 17420-17425
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, Issue.46
, pp. 17420-17425
-
-
Walterscheid, J.P.1
Nghiem, D.X.2
Kazimi, N.3
Nutt, L.K.4
McConkey, D.J.5
Norval, M.6
Ullrich, S.E.7
-
51
-
-
0024334021
-
High-affinity uptake of L-kynurenine by a Na+-independent transporter of neutral amino acids in astrocytes
-
Speciale, C.; Hares, K.; Schwarcz, R.; Brookes, N. High-affinity uptake of L-kynurenine by a Na+-independent transporter of neutral amino acids in astrocytes J. Neurosci. 1989, 9 (6) 2066-2072
-
(1989)
J. Neurosci.
, vol.9
, Issue.6
, pp. 2066-2072
-
-
Speciale, C.1
Hares, K.2
Schwarcz, R.3
Brookes, N.4
-
52
-
-
0026076136
-
Blood-brain barrier transport of kynurenines: Implications for brain synthesis and metabolism
-
Fukui, S.; Schwarcz, R.; Rapoport, S. I.; Takada, Y.; Smith, Q. R. Blood-brain barrier transport of kynurenines: implications for brain synthesis and metabolism J. Neurochem. 1991, 56 (6) 2007-2017
-
(1991)
J. Neurochem.
, vol.56
, Issue.6
, pp. 2007-2017
-
-
Fukui, S.1
Schwarcz, R.2
Rapoport, S.I.3
Takada, Y.4
Smith, Q.R.5
-
53
-
-
0033056044
-
Tryptophan metabolism and brain function: Focus on kynurenine and other indole metabolites
-
Moroni, F. Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites Eur. J. Pharmacol. 1999, 375 (1-3) 87-100
-
(1999)
Eur. J. Pharmacol.
, vol.375
, Issue.13
, pp. 87-100
-
-
Moroni, F.1
-
54
-
-
34249788738
-
Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders
-
Sas, K.; Robotka, H.; Toldi, J.; Vecsei, L. Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders J. Neurol. Sci. 2007, 257 (1-2) 221-239
-
(2007)
J. Neurol. Sci.
, vol.257
, Issue.12
, pp. 221-239
-
-
Sas, K.1
Robotka, H.2
Toldi, J.3
Vecsei, L.4
-
55
-
-
33846509169
-
Kynurenines impair energy metabolism in rat cerebral cortex
-
Schuck, P. F.; Tonin, A.; Ferreira, G. D.; Viegas, C. M.; Latini, A.; Wannmacher, C. M. D.; Wyse, A. T. D.; Dutra, C. S.; Wajner, M. Kynurenines impair energy metabolism in rat cerebral cortex Cell. Mol. Neurobiol. 2007, 27 (1) 147-160
-
(2007)
Cell. Mol. Neurobiol.
, vol.27
, Issue.1
, pp. 147-160
-
-
Schuck, P.F.1
Tonin, A.2
Ferreira, G.D.3
Viegas, C.M.4
Latini, A.5
Wannmacher, C.M.D.6
Wyse, A.T.D.7
Dutra, C.S.8
Wajner, M.9
-
56
-
-
84871925048
-
Kynurenines in the CNS: Recent advances and new questions
-
Vecsei, L.; Szalardy, L.; Fulop, F.; Toldi, J. Kynurenines in the CNS: recent advances and new questions Nat. Rev. Drug Discovery 2013, 12 (1) 64-82
-
(2013)
Nat. Rev. Drug Discovery
, vol.12
, Issue.1
, pp. 64-82
-
-
Vecsei, L.1
Szalardy, L.2
Fulop, F.3
Toldi, J.4
-
57
-
-
0027162932
-
Concentrations of serotonin and its related substances in the cerebrospinal fluid of parkinsonian patients and their relations to the severity of symptoms
-
Tohgi, H.; Abe, T.; Takahashi, S.; Takahashi, J.; Hamato, H. Concentrations of serotonin and its related substances in the cerebrospinal fluid of parkinsonian patients and their relations to the severity of symptoms Neurosci. Lett. 1993, 150 (1) 71-74
-
(1993)
Neurosci. Lett.
, vol.150
, Issue.1
, pp. 71-74
-
-
Tohgi, H.1
Abe, T.2
Takahashi, S.3
Takahashi, J.4
Hamato, H.5
-
58
-
-
27744509130
-
Kynurenine metabolism in plasma and in red blood cells in Parkinson's disease
-
Hartai, Z.; Klivenyi, P.; Janaky, T.; Penke, B.; Dux, L.; Vecsei, L. Kynurenine metabolism in plasma and in red blood cells in Parkinson's disease J. Neurol. Sci. 2005, 239 (1) 31-35
-
(2005)
J. Neurol. Sci.
, vol.239
, Issue.1
, pp. 31-35
-
-
Hartai, Z.1
Klivenyi, P.2
Janaky, T.3
Penke, B.4
Dux, L.5
Vecsei, L.6
-
59
-
-
0021357276
-
Altered serotonin metabolism in depressed patients with parkinson's disease
-
Mayeux, R.; Stern, Y.; Cote, L.; Williams, J. B. Altered serotonin metabolism in depressed patients with parkinson's disease Neurology 1984, 34 (5) 642-646
-
(1984)
Neurology
, vol.34
, Issue.5
, pp. 642-646
-
-
Mayeux, R.1
Stern, Y.2
Cote, L.3
Williams, J.B.4
-
60
-
-
0023718087
-
Changes in the blood level of serotonin in Parkinson disease
-
Karimova, M.; Aleuov, Sh. A. Changes in the blood level of serotonin in Parkinson disease Vopr. Med. Khim. 1988, 34 (1) 45-47
-
(1988)
Vopr. Med. Khim.
, vol.34
, Issue.1
, pp. 45-47
-
-
Karimova, M.1
Aleuov, Sh.A.2
-
61
-
-
84867901846
-
Urinary phenylacetylglutamine as dosing biomarker for patients with urea cycle disorders
-
Mokhtarani, M.; Diaz, G. A.; Rhead, W.; Lichter-Konecki, U.; Bartley, J.; Feigenbaum, A.; Longo, N.; Berquist, W.; Berry, S. A.; Gallagher, R.; Bartholomew, D.; Harding, C. O.; Korson, M. S.; McCandless, S. E.; Smith, W.; Vockley, J.; Bart, P. S.; Kronn, D.; Zori, R.; Cederbaum, S.; Dorrani, N.; Merritt, J. L.; Sreenath-Nagamani, S.; Summar, M.; LeMons, C.; Dickinson, K.; Coakley, D. F.; Moors, T. L.; Lee, B.; Scharschmidt, B. F. Urinary phenylacetylglutamine as dosing biomarker for patients with urea cycle disorders Mol. Genet. Metab. 2012, 107 (3) 308-314
-
(2012)
Mol. Genet. Metab.
, vol.107
, Issue.3
, pp. 308-314
-
-
Mokhtarani, M.1
Diaz, G.A.2
Rhead, W.3
Lichter-Konecki, U.4
Bartley, J.5
Feigenbaum, A.6
Longo, N.7
Berquist, W.8
Berry, S.A.9
Gallagher, R.10
Bartholomew, D.11
Harding, C.O.12
Korson, M.S.13
McCandless, S.E.14
Smith, W.15
Vockley, J.16
Bart, P.S.17
Kronn, D.18
Zori, R.19
Cederbaum, S.20
Dorrani, N.21
Merritt, J.L.22
Sreenath-Nagamani, S.23
Summar, M.24
Lemons, C.25
Dickinson, K.26
Coakley, D.F.27
Moors, T.L.28
Lee, B.29
Scharschmidt, B.F.30
more..
-
62
-
-
84897089628
-
Elevated phenylacetic acid levels do not correlate with adverse events in patients with urea cycle disorders or hepatic encephalopathy and can be predicted based on the plasma PAA to PAGN ratio
-
Mokhtarani, M.; Diaz, G. A.; Rhead, W.; Berry, S. A.; Lichter-Konecki, U.; Feigenbaum, A.; Schulze, A.; Longo, N.; Bartley, J.; Berquist, W.; Gallagher, R.; Smith, W.; McCandless, S. E.; Harding, C.; Rockey, D. C.; Vierling, J. M.; Mantry, P.; Ghabril, M.; Brown, R. S.; Dickinson, K.; Moors, T.; Norris, C.; Coakley, D.; Milikien, D. A.; Nagamani, S. C.; LeMons, C.; Lee, B.; Scharschmidt, B. F. Elevated phenylacetic acid levels do not correlate with adverse events in patients with urea cycle disorders or hepatic encephalopathy and can be predicted based on the plasma PAA to PAGN ratio Mol. Genet. Metab. 2013, 110 (4) 446-453
-
(2013)
Mol. Genet. Metab.
, vol.110
, Issue.4
, pp. 446-453
-
-
Mokhtarani, M.1
Diaz, G.A.2
Rhead, W.3
Berry, S.A.4
Lichter-Konecki, U.5
Feigenbaum, A.6
Schulze, A.7
Longo, N.8
Bartley, J.9
Berquist, W.10
Gallagher, R.11
Smith, W.12
McCandless, S.E.13
Harding, C.14
Rockey, D.C.15
Vierling, J.M.16
Mantry, P.17
Ghabril, M.18
Brown, R.S.19
Dickinson, K.20
Moors, T.21
Norris, C.22
Coakley, D.23
Milikien, D.A.24
Nagamani, S.C.25
Lemons, C.26
Lee, B.27
Scharschmidt, B.F.28
more..
-
63
-
-
0020322864
-
P-hydroxyphenylacetic acid concentrations in cerebrospinal fluid
-
Kobayashi, K.; Koide, Y.; Yoshino, K.; Shohmori, T. P-hydroxyphenylacetic acid concentrations in cerebrospinal fluid No to Shinkei 1982, 34 (8) 769-774
-
(1982)
No to Shinkei
, vol.34
, Issue.8
, pp. 769-774
-
-
Kobayashi, K.1
Koide, Y.2
Yoshino, K.3
Shohmori, T.4
-
64
-
-
0014673111
-
M-Hydroxyphenylacetic acid formation from L-dopa in man: Suppression by neomycin
-
Sandler, M.; Karoum, F.; Ruthven, C. R.; Calne, D. B. m-Hydroxyphenylacetic acid formation from L-dopa in man: suppression by neomycin Science 1969, 166 (3911) 1417-1418
-
(1969)
Science
, vol.166
, Issue.3911
, pp. 1417-1418
-
-
Sandler, M.1
Karoum, F.2
Ruthven, C.R.3
Calne, D.B.4
-
65
-
-
0035976814
-
Trimethylamine-N-oxide-induced folding of alpha-synuclein
-
Uversky, V. N.; Li, J.; Fink, A. L. Trimethylamine-N-oxide-induced folding of alpha-synuclein FEBS Lett. 2001, 509 (1) 31-35
-
(2001)
FEBS Lett.
, vol.509
, Issue.1
, pp. 31-35
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
66
-
-
79952601424
-
Normal gut microbiota modulates brain development and behavior
-
Heijtza, R. D.; Wang, S. G.; Anuar, F.; Qian, Y.; Bjorkholm, B.; Samuelsson, A.; Hibberd, M. L.; Forssberg, H.; Pettersson, S. Normal gut microbiota modulates brain development and behavior Proc. Natl. Acad. Sci. U.S.A. 2011, 108 (7) 3047-3052
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, Issue.7
, pp. 3047-3052
-
-
Heijtza, R.D.1
Wang, S.G.2
Anuar, F.3
Qian, Y.4
Bjorkholm, B.5
Samuelsson, A.6
Hibberd, M.L.7
Forssberg, H.8
Pettersson, S.9
-
67
-
-
41149099000
-
Symbiotic gut microbes modulate human metabolic phenotypes
-
Li, M.; Wang, B. H.; Zhang, M. H.; Rantalainen, M.; Wang, S. Y.; Zhou, H. K.; Zhang, Y.; Shen, J.; Pang, X. Y.; Zhang, M. L.; Wei, H.; Chen, Y.; Lu, H. F.; Zuo, J.; Su, M. M.; Qiu, Y. P.; Jia, W.; Xiao, C. N.; Smith, L. M.; Yang, S. L.; Holmes, E.; Tang, H. R.; Zhao, G. P.; Nicholson, J. K.; Li, L. J.; Zhao, L. P. Symbiotic gut microbes modulate human metabolic phenotypes Proc. Natl. Acad. Sci. U.S.A. 2008, 105 (6) 2117-2122
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, Issue.6
, pp. 2117-2122
-
-
Li, M.1
Wang, B.H.2
Zhang, M.H.3
Rantalainen, M.4
Wang, S.Y.5
Zhou, H.K.6
Zhang, Y.7
Shen, J.8
Pang, X.Y.9
Zhang, M.L.10
Wei, H.11
Chen, Y.12
Lu, H.F.13
Zuo, J.14
Su, M.M.15
Qiu, Y.P.16
Jia, W.17
Xiao, C.N.18
Smith, L.M.19
Yang, S.L.20
Holmes, E.21
Tang, H.R.22
Zhao, G.P.23
Nicholson, J.K.24
Li, L.J.25
Zhao, L.P.26
more..
-
68
-
-
84884671077
-
A metabolomic view of how the human gut microbiota impacts the host metabolome using humanized and gnotobiotic mice
-
Marcobal, A.; Kashyap, P. C.; Nelson, T. A.; Aronov, P. A.; Donia, M. S.; Spormann, A.; Fischbach, M. A.; Sonnenburg, J. L. A metabolomic view of how the human gut microbiota impacts the host metabolome using humanized and gnotobiotic mice ISME J. 2013, 7 (10) 1933-1943
-
(2013)
ISME J.
, vol.7
, Issue.10
, pp. 1933-1943
-
-
Marcobal, A.1
Kashyap, P.C.2
Nelson, T.A.3
Aronov, P.A.4
Donia, M.S.5
Spormann, A.6
Fischbach, M.A.7
Sonnenburg, J.L.8
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