Rapid T2- and susceptometry-based CMRO2 quantification with interleaved TRUST (iTRUST)

NeuroImage

Volumn 106, Issue , 2015, Pages 441-450

  Rodgers, Zachary B ^a   Englund, Erin K ^a   Langham, Michael C ^a   Magland, Jeremy F ^a   Wehrli, Felix W ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Blood oxygen saturation; CMRO2; Hypercapnia; MR susceptometry; Phase contrast MRI; TRUST

Indexed keywords

ADULT; ARTICLE; BRAIN BLOOD FLOW; BRAIN MAPPING; CAPNOMETRY; CEREBRAL METABOLIC RATE OF OXYGEN; CEREBROSPINAL FLUID; DEOXYGENATION; ERYTHROCYTE; FEMALE; GRAY MATTER; HUMAN; HUMAN EXPERIMENT; HYPERCAPNIA; IMAGE ANALYSIS; IMAGE RECONSTRUCTION; INTERLEAVED T2 RELAXATION UNDER SPIN TAGGING; MALE; METHODOLOGY; NEUROIMAGING; NORMAL HUMAN; OXIMETRY; OXYGEN SATURATION; PULSE OXIMETRY; SIGNAL NOISE RATIO; SUPERIOR SAGITTAL SINUS; SUSCEPTOMETRY BASED OXIMETRY; VALIDATION PROCESS; WHITE MATTER; BIOLOGICAL MODEL; BRAIN CORTEX; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PROCEDURES; VALIDATION STUDY; VASCULARIZATION; YOUNG ADULT;

OXYGEN;

ADULT; CEREBRAL CORTEX; FEMALE; HUMANS; HYPERCAPNIA; MAGNETIC RESONANCE IMAGING; MALE; MODELS, NEUROLOGICAL; OXIMETRY; OXYGEN; YOUNG ADULT;

EID: 84920157763     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2014.10.061     Document Type: Article

References (60)

1. An H.Y., Lin W.L. Quantitative measurements of cerebral blood oxygen saturation using magnetic resonance imaging. J. Cereb. Blood Flow Metab. 2000, 20(8):1225-1236.
2. Barhoum S., Rodgers Z.B., Langham M., Magland J.F., Li C., Wehrli F.W. Comparison of MRI methods for measuring whole-brain venous oxygen saturation. Magn. Reson. Med. 2014.
3. Blockley N.P., Griffeth V.E., Simon A.B., Buxton R.B. A review of calibrated blood oxygenation level-dependent (BOLD) methods for the measurement of task-induced changes in brain oxygen metabolism. NMR Biomed. 2013, 26(8):987-1003.
4. Bolar D.S., Rosen B.R., Sorensen A.G., Adalsteinsson E. QUantitative Imaging of eXtraction of oxygen and TIssue consumption (QUIXOTIC) using venular-targeted velocity-selective spin labeling. Magn. Reson. Med. 2011, 66(6):1550-1562.
5. Borghammer P., Chakravarty M., Jonsdottir K.Y., Sato N., Matsuda H., Ito K., Arahata Y., Kato T., Gjedde A. Cortical hypometabolism and hypoperfusion in Parkinson's disease is extensive: probably even at early disease stages. Brain Struct. Funct. 2010, 214(4):303-317.
6. Bulte D.P., Kelly M., Germuska M., Xie J., Chappell M.A., Okell T.W., Bright M.G., Jezzard P. Quantitative measurement of cerebral physiology using respiratory-calibrated MRI. NeuroImage 2012, 60(1):582-591.
7. Chen J.J., Pike G.B. Human whole blood T2 relaxometry at 3Tesla. Magn. Reson. Med. 2009, 61(2):249-254.
8. Chen J.J., Pike G.B. Global cerebral oxidative metabolism during hypercapnia and hypocapnia in humans: implications for BOLD fMRI. J. Cereb. Blood Flow Metab. 2010, 30(6):1094-1099.
9. Davis T.L., Kwong K.K., Weisskoff R.M., Rosen B.R. Calibrated functional MRI: mapping the dynamics of oxidative metabolism. Proc. Natl. Acad. Sci. 1998, 95(4):1834-1839.
10. Doyle M., Walsh E.G., Blackwell G.G., Pohost G.M. Block regional interpolation scheme for k-space (BRISK): a rapid cardiac imaging technique. Magn. Reson. Med. 1995, 33(2):163-170.
11. Driver I.D., Hall E.L., Wharton S.J., Pritchard S.E., Francis S.T., Gowland P.A. Calibrated BOLD using direct measurement of changes in venous oxygenation. NeuroImage 2012, 63(3):1178-1187.
12. Englund E.K., Langham M.C., Li C., Rodgers Z.B., Floyd T.F., Mohler E.R., Wehrli F.W. Combined measurement of perfusion, venous oxygen saturation, and skeletal muscle T2* during reactive hyperemia in the leg. J. Cardiovasc. Magn. Reson. 2013, 15:70.
13. Fan A.P., Benner T., Bolar D.S., Rosen B.R., Adalsteinsson E. Phase-based regional oxygen metabolism (PROM) using MRI. Magn. Reson. Med. 2012, 67(3):669-678.
14. Fan A.P., Bilgic B., Gagnon L., Witzel T., Bhat H., Rosen B.R., Adalsteinsson E. Quantitative oxygenation venography from MRI phase. Magn. Reson. Med. 2014, 72(1):149-159.
15. Fernandez-Seara M.A., Techawiboonwong A., Detre J.A., Wehrli F.W. MR susceptometry for measuring global brain oxygen extraction. Magn. Reson. Med. 2006, 55(5):967-973.
16. Gardener A.G., Francis S.T., Prior M., Peters A., Gowland P.A. Dependence of blood R2 relaxivity on CPMG echo-spacing at 2.35 and 7T. Magn. Reson. Med. 2010, 64(4):967-974.
17. Gauthier C.J., Desjardins-Crepeau L., Madjar C., Bherer L., Hoge R.D. Absolute quantification of resting oxygen metabolism and metabolic reactivity during functional activation using QUO2 MRI. NeuroImage 2012, 63(3):1353-1363.
18. Ge Y., Zhang Z., Lu H., Tang L., Jaggi H., Herbert J., Babb J.S., Rusinek H., Grossman R.I. Characterizing brain oxygen metabolism in patients with multiple sclerosis with T2-relaxation-under-spin-tagging MRI. J. Cereb. Blood Flow Metab. 2012, 32(3):403-412.
19. Golay X., Silvennoinen M.J., Zhou J., Clingman C.S., Kauppinen R.A., Pekar J.J., van Zij P.C. Measurement of tissue oxygen extraction ratios from venous blood T(2): increased precision and validation of principle. Magn. Reson. Med. 2001, 46(2):282-291.
20. Guo J., Wong E.C. Venous oxygenation mapping using velocity-selective excitation and arterial nulling. Magn. Reson. Med. 2012, 68(5):1458-1471.
21. Gupta A., Chazen J.L., Hartman M., Delgado D., Anumula N., Shao H., Mazumdar M., Segal A.Z., Kamel H., Leifer D., Sanelli P.C. Cerebrovascular reserve and stroke risk in patients with carotid stenosis or occlusion: a systematic review and meta-analysis. Stroke 2012, 43(11):2884-2891.
22. Haacke E.M., Lai S., Reichenbach J.R., Kuppusamy K., Hoogenraad F.G.C., Takeichi H., Lin W.L. In vivo measurement of blood oxygen saturation using magnetic resonance imaging: a direct validation of the blood oxygen level-dependent concept in functional brain imaging. Hum. Brain Mapp. 1997, 5(5):341-346.
23. He X., Yablonskiy D.A. Quantitative BOLD: mapping of human cerebral deoxygenated blood volume and oxygen extraction fraction: default state. Magn. Reson. Med. 2007, 57(1):115-126.
24. Herscovitch P., Raichle M.E. What is the correct value for the brain-blood partition coefficient for water?. J. Cereb. Blood Flow Metab. 1985, 5(1):65-69.
25. Ishii K., Kitagaki H., Kono M., Mori E. Decreased medial temporal oxygen metabolism in Alzheimer's disease shown by PET. J. Nucl. Med. 1996, 37(7):1159-1165.
26. Ito H., Ibaraki M., Kanno I., Fukuda H., Miura S. Changes in cerebral blood flow and cerebral oxygen metabolism during neural activation measured by positron emission tomography: comparison with blood oxygenation level-dependent contrast measured by functional magnetic resonance imaging. J. Cereb. Blood Flow Metab. 2005, 25(3):371-377.
27. Jain V., Langham M.C., Wehrli F.W. MRI estimation of global brain oxygen consumption rate. J. Cereb. Blood Flow Metab. 2010, 30(9):1598-1607.
28. Jain V., Langham M.C., Floyd T.F., Jain G., Magland J.F., Wehrli F.W. Rapid magnetic resonance measurement of global cerebral metabolic rate of oxygen consumption in humans during rest and hypercapnia. J. Cereb. Blood Flow Metab. 2011, 31(7):1504-1512.
29. Jain V., Abdulmalik O., Propert K.J., Wehrli F.W. Investigating the magnetic susceptibility properties of fresh human blood for noninvasive oxygen saturation quantification. Magn. Reson. Med. 2012, 68(3):863-867.
30. Jain V., Magland J., Langham M., Wehrli F.W. High temporal resolution in vivo blood oximetry via projection-based T(2) measurement. Magn. Reson. Med. 2014, 70:785-790.
31. Kety S.S., Schmidt C.F. The effects of altered arterial tensions of carbon dioxide and oxygen on cerebral blood flow and cerebral oxygen consumption of normal young men. J. Clin. Investig. 1948, 27(4):484-492.
32. Kim S.G., Ogawa S. Biophysical and physiological origins of blood oxygenation level-dependent fMRI signals. J. Cereb. Blood Flow Metab. 2012, 32(7):1188-1206.
33. Krishnamurthy L.C., Liu P., Ge Y., Lu H. Vessel-specific quantification of blood oxygenation with T -relaxation-under-phase-contrast MRI. Magn. Reson. Med. 2013, 71:978-989.
34. Krishnamurthy L.C., Liu P., Xu F., Uh J., Dimitrov I., Lu H. Dependence of blood T(2) on oxygenation at 7T: in vitro calibration and in vivo application. Magn. Reson. Med. 2014, 71(6):2035-2042.
35. Langham M.C., Magland J.F., Floyd T.F., Wehrli F.W. Retrospective correction for induced magnetic field inhomogeneity in measurements of large-vessel hemoglobin oxygen saturation by MR susceptometry. Magn. Reson. Med. 2009, 61(3):626-633.
36. Li C., Langham M.C., Epstein C.L., Magland J.F., Wu J., Gee J., Wehrli F.W. Accuracy of the cylinder approximation for susceptometric measurement of intravascular oxygen saturation. Magn. Reson. Med. 2012, 67(3):808-813.
37. Liu P., Xu F., Lu H. Test-retest reproducibility of a rapid method to measure brain oxygen metabolism. Magn. Reson. Med. 2013, 69(3):675-681.
38. 2) in neonates using MRI. NMR Biomed. 2014, 27(3):332-340.
39. Liu J., Zhu Y.S., Khan M.A., Brunk E., Martin-Cook K., Weiner M.F., Cullum C.M., Lu H., Levine B.D., Diaz-Arrastia R., Zhang R. Global brain hypoperfusion and oxygenation in amnestic mild cognitive impairment. Alzheimers Dement. 2014, 10(2):162-170.
40. Lu H., Ge Y. Quantitative evaluation of oxygenation in venous vessels using T2-relaxation-under-spin-tagging MRI. Magn. Reson. Med. 2008, 60(2):357-363.
41. Lu H., Xu F., Grgac K., Liu P., Qin Q., van Zijl P. Calibration and validation of TRUST MRI for the estimation of cerebral blood oxygenation. Magn. Reson. Med. 2012, 67(1):42-49.
42. Magland J., Wehrli F.W. Pulse sequence programming in a dynamic visual environment. Proceedings of the 14th Annual Meeting of ISMRM, Seattle, Washington, USA 2006, 3032.
43. Matthews P.M., Honey G.D., Bullmore E.T. Applications of fMRI in translational medicine and clinical practice. Nat. Rev. Neurosci. 2006, 7(9):732-744.
44. Mugler J.P., Brookeman J.R. Three-dimensional magnetization-prepared rapid gradient-echo imaging (3D MP RAGE). Magn. Reson. Med. 1990, 15(1):152-157.
45. Peng S.L., Dumas J.A., Park D.C., Liu P., Filbey F.M., McAdams C.J., Pinkham A.E., Adinoff B., Zhang R., Lu H. Age-related increase of resting metabolic rate in the human brain. NeuroImage 2014, 98:176-183.
46. Qin Q., Grgac K., van Zijl P.C. Determination of whole-brain oxygen extraction fractions by fast measurement of blood T(2) in the jugular vein. Magn. Reson. Med. 2011, 65(2):471-479.
47. Richiardi J., Monsch A.U., Haas T., Barkhof F., Van de Ville D., Radu E.W., Kressig R.W., Haller S. Altered cerebrovascular reactivity velocity in mild cognitive impairment and Alzheimer's disease. Neurobiol. Aging 2014.
48. Rodgers Z.B., Jain V., Englund E.K., Langham M.C., Wehrli F.W. High temporal resolution MRI quantification of global cerebral metabolic rate of oxygen consumption in response to apneic challenge. J. Cereb. Blood Flow Metab. 2013, 33(10):1514-1522.
49. Rodgers Z.B., Kini L., Langham M., Magland J., Wehrli F.W. High temporal resolution, simultaneous quantification of intravascular blood flow and oxygen saturation with BRISK k-space sampling. Proceedings of 21st Annual Meeting of ISMRM, Salt Lake City, Utah, USA 2013, 1351.
50. Rolfe D.F., Brown G.C. Cellular energy utilization and molecular origin of standard metabolic rate in mammals. Physiol. Rev. 1997, 77(3):731-758.
51. Smith S.M. Fast robust automated brain extraction. Hum. Brain Mapp. 2002, 17(3):143-155.
52. Spees W.M., Yablonskiy D.A., Oswood M.C., Ackerman J.J. Water proton MR properties of human blood at 1.5Tesla: magnetic susceptibility, T(1), T(2), T*(2), and non-Lorentzian signal behavior. Magn. Reson. Med. 2001, 45(4):533-542.
53. Van Vaals J.J., Brummer M.E., Thomas Dixon W., Tuithof H.H., Engels H., Nelson R.C., Gerety B.M., Chezmar J.L., Den Boer J.A. "Keyhole" method for accelerating imaging of contrast agent uptake. J. Magn. Reson. Imaging 1993, 3(4):671-675.
54. Wright G.A., Hu B.S., Macovski A. Estimating oxygen saturation of blood in vivo with MR imaging at 1.5T. J. Magn. Reson. Imaging 1991, 1(3):275-283.
55. 2) by MRI. Magn. Reson. Med. 2009, 62(1):141-148.
56. Xu F., Uh J., Brier M.R., Hart J., Yezhuvath U.S., Gu H., Yang Y., Lu H. The influence of carbon dioxide on brain activity and metabolism in conscious humans. J. Cereb. Blood Flow Metab. 2011, 31(1):58-67.
57. Xu F., Liu P., Pascual J.M., Xiao G., Lu H. Effect of hypoxia and hyperoxia on cerebral blood flow, blood oxygenation, and oxidative metabolism. J. Cereb. Blood Flow Metab. 2012, 32(10):1909-1918.
58. Xu F., Uh J., Liu P., Lu H. On improving the speed and reliability of T2-relaxation-under-spin-tagging (TRUST) MRI. Magn. Reson. Med. 2012, 68(1):198-204.
59. Xu B., Liu T., Spincemaille P., Prince M., Wang Y. Flow compensated quantitative susceptibility mapping for venous oxygenation imaging. Magn. Reson. Med. 2014, 72(2):438-445.
60. Yablonskiy D.A. Cerebral metabolic rate in hypercapnia: controversy continues. J. Cereb. Blood Flow Metab. 2011, 31(7):1502-1503.