Changes in cerebral blood flow and cerebral oxygen metabolism during neural activation measured by positron emission tomography: Comparison with blood oxygenation level-dependent contrast measured by functional magnetic resonance imaging

Journal of Cerebral Blood Flow and Metabolism

Volumn 25, Issue 3, 2005, Pages 371-377

  Ito, Hiroshi ^a,b   Ibaraki, Masanobu ^a   Kanno, Iwao ^a   Fukuda, Hiroshi ^b   Miura, Shuichi ^a  

^a RESEARCH INSTITUTE FOR BRAIN AND BLOOD VESSELS AKITA   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

BOLD; CBF; CMRO2; MRI; PET

Indexed keywords

CARBON MONOXIDE; DEOXYHEMOGLOBIN; OXYGEN 15; WATER;

ADULT; ARTICLE; BLOOD OXYGENATION; BLOOD OXYGENATION LEVEL DEPENDENT CONTRAST; BRAIN BLOOD FLOW; BRAIN DEPTH STIMULATION; BRAIN OXYGEN CONSUMPTION; BRAIN REGION; CEREBELLUM; CINGULATE GYRUS; CORRELATION ANALYSIS; EXTRACTION; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HAND MOVEMENT; HUMAN; HUMAN EXPERIMENT; INTERMETHOD COMPARISON; MALE; MOTOR ACTIVITY; MOTOR CORTEX; NORMAL HUMAN; OXYGEN EXTRACTION FRACTION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; TASK PERFORMANCE; VENOUS BLOOD;

ADULT; BRAIN; CEREBROVASCULAR CIRCULATION; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEURONS; OXYGEN; POSITRON-EMISSION TOMOGRAPHY; REFERENCE VALUES;

EID: 14644430981     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600030     Document Type: Article

References (38)

1. Allison JD, Meador KJ, Loring DW, Figueroa RE, Wright JC (2000) Functional MRI cerebral activation and deactivation during finger movement. Neurology 54:135-42
2. Belliveau JW, Kennedy Jr DN, McKinstry RC, Buchbinder BR, Weisskoff RM, Cohen MS, Vevea JM, Brady TJ, Rosen BR (1991) Functional mapping of the human visual cortex by magnetic resonance imaging. Science 254:716-9
3. Boxerman JL, Hamberg LM, Rosen BR, Weisskoff RM (1995) MR contrast due to intravascular magnetic susceptibility perturbations. Magn Reson Med 34:555-566
4. Davis TL, Kwong KK, Weisskoff RM, Rosen BR (1998) Calibrated functional MRI: mapping the dynamics of oxidative metabolism. Proc Natl Acad Sci USA 95:1834-9
5. Fox PT, Raichle ME (1984) Stimulus rate dependence of regional cerebral blood flow in human striate cortex, demonstrated by positron emission tomography. J Neurophysiol 51:1109-20
6. Fox PT, Raichle ME (1985) Stimulus rate determines regional brain blood flow in striate cortex. Ann Neurol 17:303-5
7. Fox PT, Raichle ME (1986) Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc Natl Acad Sci USA 83:1140-4
8. Friston KJ, Frith CD, Liddle PF, Dolan RJ, Lammertsma AA, Frackowiak RS (1990) The relationship between global and local changes in PET scans. J Cereb Blood Flow Metab 10:458-66
9. Hathout GM, Gambhir SS, Gopi RK, Kirlew KA, Choi Y, So G, Gozal D, Harper R, Lufkin RB, Hawkins R (1995) A quantitative physiologic model of blood oxygenation for functional magnetic resonance imaging. Invest Radiol 30:669-82
10. Herscovitch P, Mintun MA, Raichle ME (1985) Brain oxygen utilization measured with oxygen-15radiotracers and positron emission tomography: generation of metabolic images. J Nucl Med 26:416-7
11. Hoge RD, Atkinson J, Gill B, Crelier GR, Marrett S, Pike GB (1999) Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: the deoxyhemoglobin dilution model. Magn Reson Med 42:849-63
12. 15O] water and dynamic positron emission tomography. J Cereb Blood Flow Metab 8:285-8
13. Iida H, Jones T, Miura S (1993) Modeling approach to eliminate the need to separate arterial plasma in oxygen-15 inhalation positron emission tomography. J Nucl Med 34:1333-40
14. 15O autoradiography and positron emission tomography, with respect to the dispersion of the input function. J Cereb Blood Flow Metab 6:536-45
15. Iida H, Miura S, Kanno I, Ogawa T, Uemura K (1996) A new PET camera for noninvasive quantitation of physiological functional parametric images: Headtome-V-dual. In: Quantification of Brain Function Using PET (Myers R, Cunningham V, Bailey D, et al, eds), San Diego: Academic Press, 57-61
16. Iida H, Miura S, Shoji Y, Ogawa T, Kado H, Narita Y, Hatazawa J, Eberl S, Kanno I, Uemura K (1998) Noninvasive quantitation of cerebral blood flow using oxygen-15-water and a dual-PET system. Journal of Nuclear Medicine 39:1789-98
17. Ito H, Kanno I, Iida H, Hatazawa J, Shimosegawa E, Tamura H, Okudera T (2001a) Arterial fraction of cerebral blood volume in humans measured by positron emission tomography. Ann Nucl Med 15:111-6
18. Ito H, Kanno I, Shimosegawa E, Tamura H, Okane K, Hatazawa J (2002) Hemodynamic changes during neural deactivation in human brain: a positron emission tomography study of crossed cerebellar diaschisis. Ann Nucl Med 16:249-54
19. Ito H, Takahashi K, Hatazawa J, Kim SG, Kanno I (2001b) Changes in human regional cerebral blood flow and cerebral blood volume during visual stimulation measured by positron emission tomography. J Cereb Blood Flow Metab 21:608-12
20. 15O autoradiographic method and positron emission tomography. J Cereb Blood Flow Metab 7: 143-153
21. Kawashima R, Yamada K, Kinomura S, Yamaguchi T, Matsui H, Yoshioka S, Fukuda H (1993) Regional cerebral blood flow changes of cortical motor areas and prefrontal areas in humans related to ipsilateral and contralateral hand movement. Brain Res 623:33-40
22. 2 from CBF and BOLD changes: significant increase of oxygen consumption rate during visual stimulation. Magn Reson Med 41:1152-61
23. Kim SG, Ugurbil K (1997) Comparison of blood oxygenation and cerebral blood flow effects in fMRI: estimation of relative oxygen consumption change. Magn Reson Med 38:59-65
24. Lammertsma AA, Jones T (1983) Correction for the presence of intravascular oxygen-15 in the steady-state technique for measuring regional oxygen extraction ratio in the brain: 1. Description of the method. J Cereb Blood Flow Metab 3:416-24
25. 15O and positron emission tomography. J Cereb Blood Flow Metab 7: 421-426
26. Mintun MA, Raichle ME, Martin WR, Herscovitch P (1984) Brain oxygen utilization measured with O-15 radiotracers and positron emission tomography. J Nucl Med 25:177-87
27. Ogawa S, Lee TM, Kay AR, Tank DW (1990) Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci USA 87:9868-9872
28. Ogawa S, Menon RS, Tank DW, Kim SG, Merkle H, Ellermann JM, Ugurbil K (1993) Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. A comparison of signal characteristics with a biophysical model. Biophys J 64:803-12
29. Ogawa S, Tank DW, Menon R, Ellermann JM, Kim SG, Merkle H, Ugurbil K (1992) Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci USA 89:5951-5
30. Oja JM, Gillen JS, Kauppinen RA, Kraut M, van Zijl PC (1999) Determination of oxygen extraction ratios by magnetic resonance imaging. J Cereb Blood Flow Metab 19:1289-95
31. Oldfield RC (1971) The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9:97-113
32. Raichle ME (1998) Behind the scenes of functional brain imaging: a historical and physiological perspective. Proc Natl Acad Sci USA 95:765-72
33. 15O. II. Implementation and validation. J Nucl Med 24:790-8
34. Schwarzbauer C, Heinke W (1999) Investigating the dependence of BOLD contrast on oxidative metabolism. Magn Reson Med 41:537-43
35. Seitz RJ, Roland PE (1992) Vibratory stimulation increases and decreases the regional cerebral blood flow and oxidative metabolism: a positron emission tomography (PET) study. Acta Neurol Scand 86:60-67
36. Talairach J, Tournoux P (1988) Co-planar Stereotaxic Atlas of the Human Brain. Stuttgart, Germany: Georg Thieme Verlag
37. Turner R, Howseman A, Rees GE, Josephs O, Friston K (1998) Functional magnetic resonance imaging of the human brain: data acquisition and analysis. Exp Brain Res 123:5-12
38. Vafaee MS, Gjedde A (2000) Model of blood-brain transfer of oxygen explains nonlinear flow-metabolism coupling during stimulation of visual cortex. J Cereb Blood Flow Metab 20:747-54