Determination of whole-brain oxygen extraction fractions by fast measurement of blood T2 in the jugular vein

Magnetic Resonance in Medicine

Volumn 65, Issue 2, 2011, Pages 471-479

  Qin, Qin ^a,b   Grgac, Ksenija ^a,b,c   Van Zijl, Peter C M ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Carr Purcell Meiboom Gill; internal jugular vein; oxygen extraction fraction

Indexed keywords

CALIBRATION; COMPUTERIZED TOMOGRAPHY; EXTRACTION; OXYGEN; OXYGENATION; SATURATION MAGNETIZATION; SIGNAL TO NOISE RATIO;

BLOOD OXYGEN LEVEL DEPENDENTS; CALIBRATION CURVES; CARR-PURCELL; HIGH SIGNAL-TO-NOISE RATIO; INTERNAL JUGULAR VEINS; LONGITUDINAL MAGNETIZATION; OXYGEN EXTRACTION FRACTIONS; PHYSIOLOGICAL HOMEOSTASIS;

BLOOD;

OXYGEN;

ADULT; ARTERIAL OXYGEN SATURATION; ARTICLE; BLOOD FLOW; BLOOD OXYGENATION; BOLD SIGNAL; BRAIN OXYGEN CONSUMPTION; CALIBRATION; CONTAMINATION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEMATOCRIT; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; INTERNAL JUGULAR VEIN; MAGNETISM; MALE; NORMAL HUMAN; OXYGEN BLOOD LEVEL; OXYGEN EXTRACTION FRACTION; PERFUSION; PHANTOM; SIGNAL NOISE RATIO; STEADY STATE;

EID: 79251575007     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.22556     Document Type: Article

References (44)

1. Kety SS, Schmidt CF,. The effects of altered arterial tensions of carbon dioxide and oxygen on cerebral blood flow and cerebral oxygen consumption of normal young men. J Clin Invest 1948; 27: 484-492.
2. Ogawa S, Menon RS, Tank DW, Kim SG, Merkle H, Ellermann JM, Ugurbil K,. Functional brain mapping by blood oxygenation level-dependent contrast magnetic-resonance-imagingâa comparison of signal characteristics with a biophysical model. Biophys J 1993; 64: 803-812.
3. van Zijl PCM, Eleff SM, Ulatowski JA, Oja JME, Ulug AM, Traystman RJ, Kauppinen RA,. Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging. Nat Med 1998; 4: 159-167.
4. Buxton RB, Frank LR,. A model for the coupling between cerebral blood flow and oxygen metabolism during neural stimulation. J Cereb Blood Flow Metab 1997; 17: 64-72.
5. Lu HZ, Zhao CG, Ge YL, Lewis-Amezcua K,. Baseline blood oxygenation modulates response amplitude: physiologic basis for intersubject variations in functional MRI signals. Magn Reson Med 2008; 60: 364-372.
6. Siesjo BK,. Cerebral-circulation and metabolism. J Neurosurg 1984; 60: 88-908.
7. Meyer ME, Yu O, Eclancher B, Grucker D, Chambron J,. NMR relaxation rates and blood oxygenation level. Magn Reson Med 1995; 34: 234-241.
8. Gillis P, Peto S, Moiny F, Mispelter J, Cuenod CA,. Proton transverse nuclear magnetic-relaxation in oxidized bloodâa numerical approach. Magn Reson Med 1995; 33: 93-100.
9. Bryant RG, Marill K, Blackmore C, Francis C,. Magnetic-relaxation in blood and blood-clots. Magn Reson Med 1990; 13: 133-144.
10. Gomori JM, Grossman RI, Yuip C, Asakura T,. NMR relaxation-times of blood-dependence on field-strength, oxidation-state, and cell integrity. J Comput Assist Tomogr 1987; 11: 684-690.
11. Brooks RA, Dichiro G,. Magnetic-resonance-imaging of stationary bloodâa review. Med Phys 1987; 14: 903-913.
12. Thulborn KR, Waterton JC, Matthews PM, Radda GK,. Oxygenation dependence of the transverse relaxation-time of water protons in whole-blood at high-field. Biochim Biophys Acta 1982; 714: 265-270.
13. Wright GA, Hu BS, Macovski A,. Estimating oxygen-saturation of blood invivo with MR imaging at 1.5 T. J Magn Reson Imaging 1991; 1: 275-283.
14. Foltz WD, Merchant N, Downar R, Stainsby TA, Wright GA,. Coronary venous oximetry using MRI. Magn Reson Med 1999; 42: 837-848.
15. Oja JME, Gillen JS, Kauppinen RA, Kraut M, van Zijl PCM,. Determination of oxygen extraction ratios by magnetic resonance imaging. J Cereb Blood Flow Metab 1999; 19: 1289-1295.
16. Golay X, Silvennoinen MJ, Zhou JY, Clingman CS, Kauppinen RA, Pekar JJ, van Zijl PCM,. Measurement of tissue oxygen extraction ratios from venous blood T-2: increased precision and validation of principle. Magn Reson Med 2001; 46: 282-291.
17. Xu F, Ge YL, Lu HZ,. Noninvasive quantification of whole-brain cerebral metabolic rate of oxygen (CMRO2) by MRI. Magn Reson Med 2009; 62: 141-148.
18. Brittain JH, Hu BS, Wright GA, Meyer CH, Macovski A, Nishimura DG,. Coronary angiography with magnetization-prepared T-2 contrast. Magn Reson Med 1995; 33: 689-696.
19. Lu HZ, Ge YL,. Quantitative evaluation of oxygenation in venous vessels using T2-relaxation-under-spin-tagging MRI. Magn Reson Med 2008; 60: 357-363.
20. Purves MJ,. The physiology of the cerebral circulation. Cambridge: Cambridge University Press; 1972.
21. Levitt MH, Freeman R, Frenkiel T,. Broad-band heteronuclear decoupling. J Magn Reson 1982; 47: 328-330.
22. Foltz WD, Stainsby JA, Wright GA,. T-2 accuracy on a whole-body imager. Magn Reson Med 1997; 38: 759-768.
23. Qin Q, Van Zijl PCM,. Measuring blood T1 in the jugular vein: juggling size, speed and precision. Proc Intl Soc Mag Reson Med (Honolulu) 2009; 17: 3624.
24. Garwood M, Yong K,. Symmetrical pulses to induce arbitrary flip angles with compensation for RF Inhomogeneity and resonance offsets. J Magn Reson 1991; 94: 511-525.
25. Pucheu A, Evans J, Thomas D, Scheuble C, Pucheu M,. Doppler ultrasonography of normal neck veins. J Clin Ultrasound 1994; 22: 367-373.
26. Zhao JM, Clingman CS, Narvainen MJ, Kauppinen RA, van Zijl PCM,. Oxygenation and Hematocrit dependence of transverse relaxation rates of blood at 3T. Magn Reson Med 2007; 58: 592-597.
27. Chen JJ, Pike GB,. Human whole blood T-2 relaxometry at 3 Tesla. Magn Reson Med 2009; 61: 249-254.
28. Stefanovic B, Pike GB,. Human whole-blood relaxometry at 1.5T: assessment of diffusion and exchange models. Magn Reson Med 2004; 52: 716-723.
29. Jensen JH, Chandra R,. NMR relaxation in tissues with weak magnetic inhomogeneities. Magn Reson Med 2000; 44: 144-156.
30. Brooks RA, Moiny F, Gillis P,. On T-2-shortening by weakly magnetized particles: the chemical exchange model. Magn Reson Med 2001; 45: 1014-1020.
31. Benga G, Borza T,. Diffusional water permeability of mammalian red blood cells. Comp Biochem Physiol B 1995; 112: 653-659.
32. Silvennoinen MJ, Clingman CS, Golay X, Kauppinen RA, van Zijl PCM,. Comparison of the dependence of blood R-2 and R (2) on oxygen saturation at 1.5 and 4.7 Tesla. Magn Reson Med 2003; 49: 47-60.
33. Blackshear WM, Phillips DJ, Chikos PM, Harley JD, Thiele BL, Strandness DE,. Carotid-artery velocity patterns in normal and stenotic vessels. Stroke 1980; 11: 67-71.
34. Nezafat R, Stuber M, Ouwerkerk R, Gharib AM, Desai MY, Pettigrew RI,. B-1-insensitive T-2 preparation for improved coronary magnetic resonance angiography at 3 T. Magn Reson Med 2006; 55: 858-864.
35. Chieregato A, Calzolari F, Trasforini G, Targa L, Latronico N,. Normal jugular bulb oxygen saturation. J Neurol Neurosurg Psychiatry 2003; 74: 784-786.
36. Leenders KL, Perani D, Lammertsma AA, Heather JD, Buckingham P, Healy MJR, Gibbs JM, Wise RJS, Hatazawa J, Herold S, Beaney RP, Brooks DJ, Spinks T, Rhodes C, Frackowiak RSJ, Jones T,. Cerebral blood-flow, blood-volume and oxygen utilizationânormal values and effect of age. Brain 1990; 113: 27-47.
37. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL,. A default mode of brain function. Proc Natl Acad Sci USA 2001; 98: 676-682.
38. Fox PT, Raichle ME, Mintun MA, Dence C,. Nonoxidative glucose consumption during focal physiologic neural activity. Science 1988; 241: 462-464.
39. An HY, Lin WL,. Quantitative measurements of cerebral blood oxygen saturation using magnetic resonance imaging. J Cereb Blood Flow Metab 2000; 20: 1225-1236.
40. He X, Yablonskiy DA,. Quantitative BOLD: mapping of human cerebral deoxygenated blood volume and oxygen extraction fraction: default state. Magn Reson Med 2007; 57: 115-126.
41. Fernandez-Seara MA, Techawiboonwong A, Detre JA, Wehrli FW,. MR susceptometry for measuring global brain oxygen extraction. Magn Reson Med 2006; 55: 967-973.
42. Chen JJ, Pike GB,. Global cerebral oxidative metabolism during hypercapnia and hypocapnia in humans: implications for BOLD fMRI. J Cereb Blood Flow Metabolism 2010; 30: 1094-1099.
43. He X, Zhu M, Yablonskiy DA,. Validation of oxygen extraction fraction measurement by qBOLD technique. Magn Reson Med 2008; 60: 882-888.
44. Chanarin I, Brozovic M, Tidmarsh E, Waters D,. Blood and its disease. New York: Churchill Livingstone; 1984.